Clinical trials: PERIPHERAL VASCULAR DISEASE
Aortoiliac Atherosclerosis, Aortoiliac Occlusive Disease
IUA Committee Research Project on the Management of TASC C and D Aortoiliac Lesions
This study aims to evaluate the clinical, imaging results of endovascular revascularization of the aorto-iliac sector in comparison with aortobifemoral bypass and the hybrid approach, in patients with atherosclerotic disease of…
- Conditions
- Aortoiliac Atherosclerosis, Aortoiliac Occlusive Disease, Aortoiliac Atherosclerosis With Gangrene, Aortoiliac Atherosclerosis Without Gangrene
- Trial name
- NCT06260475
- Testing
- Aortobifemoral bypass, aortoiliac stenting
- Where
- 2 sites in Portugal
- Volunteers
- 500 people
- Sponsor
- Universidade do Porto
Cancer, Chemotherapy
Comparing of Sesame Oil, Nitroglycerin Ointment, and Aloe Vera Gel
compare the effectiveness sesame oil, aloe Vera gel, and nitroglycerin ointment prevention of phlebitis.
- Trial name
- NCT07346677
- Testing
- Sesame Oil, Aloe vera gel, Control
- Volunteers
- 190 people
- Sponsor
- University of Basrah
Brain and Central Nervous System Tumors, Kidney Cancer
Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors
RATIONALE: Tubefeeding may help maintain good nutrition and lessen weight loss in younger patients receiving chemotherapy for cancer.
- Conditions
- Brain and Central Nervous System Tumors, Kidney Cancer, Leukemia, Liver Cancer
- Trial name
- NCT00624962
- Testing
- nutritional intervention, therapeutic nutritional supplementation
- Sponsor
- Vanderbilt University
Brain and Central Nervous System Tumors, Metastatic Cancer
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Tumors
RATIONALE: Radiolabeled monoclonal antibodies can locate tumor cells and deliver radioactive tumor-killing substances to them without harming normal cells. This may be effective treatment for primary or metastatic brain tumors.
- Conditions
- Brain and Central Nervous System Tumors, Metastatic Cancer, Neuroblastoma
- Trial name
- NCT00003461
- Testing
- surgical procedure, astatine At 211 monoclonal antibody 81C6
- Where
- United States
- Sponsor
- Duke University
Other Diseases of Veins and Lymphatics
ACCUvein Measure Before ULtrasound as A facilitataTION Tool for Venous Marking
Ultrasound marking of saphenous veins before varicose vein surgery or for saphenectomy for vascular or coronary artery bypass grafting is a long, tedious, low-grading examination, generating overconsumption of many consumables…
- Trial name
- ACCUMULATION (NCT03538080)
- Testing
- ACCUVEIN plus ultrasound, Ultrasound only
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Femoral Neck Fracture, Trochanteric Pain
Hip Abductor Strengths, Limping and Trochanteric Tenderness After Hip Arthroplasty Due to Femoral Neck Fracture
A prospective cohort study to compare the direct lateral and poster-lateral approach concerning abductor function. Patients admitted with a femoral neck fracture operated with a hemiarthroplasty through a direct lateral or a…
- Trial name
- HASAP (NCT02247661)
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Sundsvall Hospital
Extravasation, Intensive Care Units (ICUs)
Prevention of Phlebitis, Infiltration and Extravasation With Infusion Monitoring System
Peripheral venous catheter complications are conditions that are frequently seen in intensive care clinics and require nursing care. The most common complications are phlebitis, infiltration and extravasation.
- Conditions
- Extravasation, Intensive Care Units (ICUs), Phlebitis, Infiltration
- Trial name
- NCT07046624
- Testing
- Infusion monitoring system developed for use by nurses in patient care
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ordu University
Peripheral Vascular Diseases
Plaque Removal Versus Open Bypass Surgery For Critical Limb Ischemia
To compare the outcome of bypass surgery and plaque excision for treatment of critical limb ischemia in the lower limbs
- Trial name
- PROOF (NCT00504088)
- Testing
- Bypass, Silverhawk Plaque Excision
- Where
- 31 sites in United States
- Sponsor
- FoxHollow Technologies
Multiple Myeloma and Plasma Cell Neoplasm
High-Dose Melphalan Followed by Peripheral Stem Cell Transplant in Treating Patients With Amyloidosis
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of plasma cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00002810
- Testing
- filgrastim, melphalan, bone marrow ablation with stem cell support
- Where
- United States
- Sponsor
- Temple University
Chronic Myeloproliferative Disorders, Graft Versus Host Disease
Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic Cancer
RATIONALE: Giving low doses of chemotherapy, such as fludarabine, and radiation therapy before a donor bone marrow or stem cell transplant helps stop the growth of cancer cells.
- Conditions
- Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma
- Trial name
- NCT00255710
- Testing
- filgrastim, cyclophosphamide, fludarabine phosphate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Raynaud's Phenomenon
Dose Response to Topical Glyceryl Trinitrate in Patients With Raynaud's Phenomenon
The purpose of this study is to evaluate the blood flow response to topical Glyceryl Trinitrate when applied to the skin of patient's fingers with Raynaud's Phenomenon.
- Trial name
- NCT00700518
- Testing
- Glyceryl Trinitrate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Procris Pharmaceuticals
Cancer
Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections
RATIONALE: White blood cells that have been treated in the laboratory may kill cells that are infected with cytomegalovirus. PURPOSE: This phase I trial is studying how well cytotoxic T cells work in treating patients who have…
- Trial name
- NCT00769613
- Testing
- cytomegalovirus IE-1-specific cytotoxic T lymphocytes, cytomegalovirus pp65-specific cytotoxic T lymphocytes, therapeutic allogeneic lymphocytes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Peripheral Arterial Disease
Clinical Evaluation of the BlueDop Vascular Expert for Assessing Peripheral Arterial Disease
This is a BlueDop Vascular Expert System (BVE) Post-Market Clinical Follow-Up (PMCF) study. The primary objective of the study is to assess the clinical applicability and diagnostic accuracy of the BVE device in subjects who…
- Trial name
- NCT05073510
- Testing
- BVE
- Where
- 4 sites in Spain
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- BlueDop Medical LTD
Chronic Myeloproliferative Disorders, Fatigue
St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer
RATIONALE: Giving St. John's wort may be effective in relieving fatigue in patients with cancer who are undergoing chemotherapy or hormone therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of St.
- Conditions
- Chronic Myeloproliferative Disorders, Fatigue, Leukemia, Lymphoma
- Trial name
- NCT00005805
- Testing
- St. John's wort
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Peripheral Arterial Disease, Flow-mediated Dilation
Vascular Effects Through Sirolimus vs. Paclitaxel DCB Implantation
Endovascular treatment of symptomatic atherosclerotic peripheral artery disease (PAD) is recommended as the primary revascularization strategy.
- Conditions
- Peripheral Arterial Disease, Flow-mediated Dilation, Drug Eluting Balloon, Infrainguinal Peripheral Arterial Disease
- Trial name
- NCT05450042
- Testing
- SELUTION SLR DCB, Paclitaxel DCB
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University Hospital, Essen
Peripheral Artery Disease
The Future of Revascularization Using a Bioprotec Graft
The main purpose of this study is the rate assessment of rescued limbs, one year after a BIOPROTEC vascular graft.
- Trial name
- REVATEC (NCT04018846)
- Testing
- Revascularization using a BIOPROTEC Graft
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Hôpital NOVO
Raynaud Disease, Hyperemia
PORH and Response to Cold in Raynaud's Phenomenon.
The main objective of the study is to determine if implication of epoxy-eicosatriénoïc acids (EETs) and NO during cutaneous post-occlusive hyperemia differs between patients with Raynaud phenomena and healthy volunteers, by…
- Conditions
- Raynaud Disease, Hyperemia, Cold
- Trial name
- REFRAIN (NCT02183779)
- Testing
- post-occlusive hyperemia, cooling box, L-NMMA and Fluconazole dermic injection
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Peripheral Arterial Disease
Randomized Clinical Trial for Ewing Amputation in the VA
This study follows the Pilot Investigation of Ewing Amputation for Veterans with PAD Undergoing a Below Knee Amputation. The 2 year pilot feasibility phase has concluded recruitment and enrollment.
- Trial name
- NCT05437562
- Testing
- Ewing Below Knee Amputation, Standard Below Knee Amputation
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Intermittent Claudication
Resistance to Aspirin and/or Clopidogrel Among Patients With PAD.
263 patients with peripheral atherosclerosis were examined to evaluate the activity of the platelets during the standard treatment, including aspirin.
- Trial name
- NCT00262561
- Testing
- Aspirin
- Where
- Denmark
- Volunteers
- 263 people
- Sponsor
- Aalborg University Hospital
Artery Disease, Peripheral
Simplified and Easy Detection of Arterial Disease in Nursing Homes
Peripheral artery disease (PAD) affects mainly elderly patients. The ankle brachial index (ABI) and ultrasound imaging are the standard diagnostic tools in PAD diagnostic and severity estimation.
- Trial name
- First-SEDAN (NCT03362710)
- Testing
- simplified tools
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Angers
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