Clinical trials: PERIPHERAL VASCULAR DISEASE
Stroke, Foot Drop
Effect of FES Interventions on Gait Dynamics in Stroke Population
Our proposal quantitatively analyzes gait dynamics of hemiplegic individuals in response to the Function Electrical Stimulation (FES) intervention and identifies the responders to the intervention.
- Trial name
- NCT01952613
- Testing
- FES
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Stroke, Complex Regional Pain Syndrome
Contrast Compression Therapy for Post-Stroke Complex Regional Pain Syndrome
This study aims to evaluate the effectiveness of contrast compression therapy as an adjunct to conventional rehabilitation in patients diagnosed with complex regional pain syndrome (CRPS) following stroke.
- Conditions
- Stroke, Complex Regional Pain Syndrome, Hemiplegia
- Trial name
- NCT07062913
- Testing
- Conventional Rehabilitation, Contrast Compression Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Meltem Gunes Akinci
Dementia, Alzheimer Disease
Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling
To develop a model to predict disease progression in a large cohort of patients across a variety of neurodegenerative diseases, including Mild Cognitive Impairment (MCI) and dementia due to any neurodegenerative disease…
- Conditions
- Dementia, Alzheimer Disease, Dementia With Lewy Bodies, Vascular Dementia
- Trial name
- CRND TorCA (NCT06529744)
- Where
- 4 sites in Canada
- Volunteers
- 500 people
- Sponsor
- University Health Network, Toronto
COVID-19, Vaccine Adverse Reaction
National Vaccine Adverse Event Reporting Survey and Etiology
If your serious vaccine-induced adverse event has been entered in the CDC Vaccine Adverse Event Reporting System (VAERS) we are interested in enrolling you for this study in order to log your symptoms.
- Conditions
- COVID-19, Vaccine Adverse Reaction, Vaccine Reaction, Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use
- Trial name
- NVAERS (NCT05095844)
- Testing
- vaccinated
- Where
- United States
- Volunteers
- 100,000 people
- Sponsor
- Neuroganics LLC
Vertigo, Peripheral, Vertigo, Brain Stem
Copeptin and the S-100b Protein in Stroke
This study evaluated the value of using copetin and protein S 100 b to eliminate the diagnosis of stroke in patients presenting with vertigo in emergency departments.
- Conditions
- Vertigo, Peripheral, Vertigo, Brain Stem, Vertigo; Central, Vertigo; Cerebral
- Trial name
- NCT03974464
- Testing
- copeptin, PS100
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Critical Limb Ischemia (CLI)
Initial Feasibility Study of the STENTiT Resorbable Fibrillated Scaffold (RFS). The RFS is Intended to Restore Lumen Patency and Blood Flow to Infrapopliteal Arteries. The RFS is a Fully Electrospun Tubular Device With a Fibrillated Microarchitecture and Designed for Transcatheter Delivery
This is the First-In-Human feasibility study of the RFS for below the knee lesions in subjects who experience critical limb ischemia due to the peripheral artery disease.
- Trial name
- VITAL-IT 1 (NCT07006467)
- Testing
- Implantation of RFS
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Stentit
Peripheral Arterial Disease, Intermittent Claudication
Non-Contrast Enhanced Peripheral Magnetic Resonance Angiography
To systematically develop, test, and refine peripheral vascular electrocardiography-gated fast spin echo magnetic resonance imaging for the accurate diagnosis of peripheral arterial disease without gadolinium contrast.
- Conditions
- Peripheral Arterial Disease, Intermittent Claudication, Peripheral Vascular Disease
- Trial name
- NCT02823444
- Testing
- Magnetic Resonance Angiography
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Critical Limb Ischemia
Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients.
This study will evaluate the efficacy and safety of apixaban 2.5 mg twice daily plus aspirin compared to the standard treatment (clopidogrel plus aspirin) in patients with critical limb ischemia undergoing infrapopliteal arterial…
- Trial name
- AGRIPPA (NCT04229264)
- Testing
- Apixaban, ASA, Clopidogrel 75mg
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Science Valley Research Institute
Diabetic Foot Ulcer, Diabetic Neuropathy Peripheral
Patients With Diabetic Neuropathy Who Receive Physiotherapy Treatment Will Have a Decrease in Diabetic Foot Ulcers
This study evaluates the effects of a physiotherapy protocol (manual therapy and exercise) in the prevention of diabetic foot ulcers in patients with diabetic neuropathy.
- Trial name
- NCT03725917
- Testing
- Physiotherapy protocol
- Where
- Spain
- Volunteers
- 143 people
- Sponsor
- Universidad Complutense de Madrid
Peripheral Arterial Disease
Dexamethasone Infusion to the Adventitia to Enhance Clinical Efficacy After Femoropopliteal Revascularization
The purpose of this study is to test if dexamethasone, an anti-inflammatory medication approved by the US Food and Drug Administration (FDA), can be injected safely into the tissue around the blood vessel wall at the time of an…
- Trial name
- DANCE (NCT01507558)
- Testing
- Administration of dexamethasone to SFA/popliteal adventitia
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Critical Limb Ischemia, Diabetes
Trial to Assess Chelation Therapy in Critical Limb Ischemia
TACT3a is a double blind, placebo-controlled, randomized trial to test a novel therapy, edetate disodium-based chelation of environmentally acquired toxic metals, to reduce cardiovascular events including amputation in high-risk…
- Trial name
- TACT3a (NCT03982693)
- Testing
- Edetate Disodium
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mt. Sinai Medical Center, Miami
Lymphoma
S9805, High-Dose Melphalan Plus Peripheral Stem Cell Transplantation Followed by Interferon Alfa in Treating Patients With Waldenstrom's Macroglobulinemia
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00003416
- Testing
- filgrastim, recombinant interferon alfa, dexamethasone
- Where
- 84 sites in United States
- Volunteers
- 9 people
- Sponsor
- SWOG Cancer Research Network
Peripheral Arterial Disease
Advance® 18PTX® Balloon Catheter Study
The Advance® 18 PTX® Balloon Catheter study is a clinical trial to study the safety and effectiveness of the Advance 18® PTX® Balloon Catheter in the treatment of lesions in the superficial femoral artery and popliteal artery.
- Trial name
- NCT00776906
- Testing
- Advance® 18PTX® Balloon Catheter, Advance® 18LP Balloon Catheter
- Where
- 4 sites in Germany, Russia
- Volunteers
- 150 people
- Sponsor
- Cook Group Incorporated
Leukemia, Lymphoma
Peripheral Blood Lymphocyte Therapy to Prevent Lymphoproliferative Disorders Caused by Epstein-Barr Virus in Patients Who Have Undergone Transplantation
RATIONALE: Peripheral blood lymphocyte therapy may be effective in the treatment and prevention of Epstein-Barr virus infection following transplantation.
- Conditions
- Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00005606
- Testing
- allogeneic Epstein-Barr virus-specific cytotoxic T lymphocytes, autologous Epstein-Barr virus-specific cytotoxic T lymphocytes
- Where
- United States
- Sponsor
- Northwestern University
Preeclampsia, Small for Gestational Age at Delivery
Early Vascular Adjustments to Prevent Preeclampsia
Women destined to develop gestational hypertensive complications often exhibit deviant hemodynamic adaptation patterns before overt clinical disease.
- Conditions
- Preeclampsia, Small for Gestational Age at Delivery, HELLP Syndrome
- Trial name
- NCT04216706
- Testing
- tailored pharmaceutical treatment
- Where
- Netherlands
- Volunteers
- 314 people
- Sponsor
- Maastricht University Medical Center
Chronic Limb-Threatening Ischemia, Diabetic Foot
Observational Study Regarding the Necessity of Inclusion of Foot Arch State Together With the Angiosome Theory Within the Wound, Ischemia and Foot Infection Classification (WIfI) to Enhance the Predictability of Wound Healing and Decision Making
This study aims to assess the complete healing or healing progress of foot ulcer within 1 year Where the patients will be classified according to foot arch state together with the angiosome theory and the WIFI clinical stage to…
- Conditions
- Chronic Limb-Threatening Ischemia, Diabetic Foot, Vascular Diseases
- Trial name
- NCT06542523
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Peripheral Artery Disease
Telehealth Delivered Home-based Walking for Vets With Peripheral Artery Disease
Walking is beneficial for adults with peripheral arterial disease. Benefits include the ability to walk for longer periods and general well being (quality of life).
- Trial name
- TREK-PAD (NCT06033924)
- Testing
- Walking Program: Internet-based, Walking Program: Telehealth-based
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Arterial Occlusive Disease, Ischemia
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1)
To evaluate the safety and efficacy of recombinant human hepatocyte growth factor (HGF) bare plasmid injection for local intramuscular injection in the treatment of patients with severe lower limb hemorrhagic disease (Rutherford…
- Conditions
- Arterial Occlusive Disease, Ischemia, Ulcers, Peripheral Vascular Disease
- Trial name
- NCT04275323
- Testing
- NL003, Normal Saline
- Where
- 13 sites in China
- Volunteers
- 302 people
- Sponsor
- Beijing Northland Biotech. Co., Ltd.
Peripheral Arterial Disease
Physical Activity Daily - An Internet-Based Walking Program for Patients With Peripheral Arterial Disease
Peripheral arterial disease (PAD) is a significant vascular condition affecting millions of adults. Exercise such as walking is highly effective for reducing PAD symptoms such as claudication (pain with walking) and improving…
- Trial name
- PAD (NCT02022423)
- Testing
- Telephone counseling, Internet-based walking program
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- University of Alabama at Birmingham
Arterial Occlusive Diseases
Thunder Trial - Local Taxan With Short Time Contact for Reduction of Restenosis in Distal Arteries
The Thunder Trail is a randomized , double-blinded, placebo controlled German multi-centre study on the efficacy of local paclitaxel for prevention of restenosis in the superficial and popliteal artery.
- Trial name
- NCT00156624
- Testing
- Balloon Angioplasty with or without drug administration
- Where
- Germany
- Volunteers
- 135 people
- Sponsor
- University Hospital Tuebingen
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