Clinical trials: PERIPHERAL VASCULAR DISEASE
Major Depressive Disorder
Linking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age Adults
The objective of this proposal is to determine whether heightened negative affective responsivity (NA-R) to daily stressors is related to blunted nitric oxide (NO)-mediated endothelium-dependent dilation (EDD) in working age…
- Trial name
- NCT06860724
- Testing
- NG-nitro-L-arginine methyl ester (L-NAME)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Coronary Heart Disease
Association Between Mitochondrial DNA Content and Risk of Coronary Heart Disease
Compelling epidemiological evidence indicates that alterations of mitochondrial DNA, including mutations and abnormal content of mitochondrial DNA (mtDNA), are associated with the initiation and development of cardiovascular…
- Trial name
- NCT02500823
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Diabetic Foot
Effect of Subtalar and Talocrural Joint Mobilization on Foot Ranges and Posture in Diabetic Patients
The aim of this research is to determine the Effects of mobilizations on foot ranges and posture in people with Type 2 Diabetes Mellitus. Randomized controlled trials will be done at Dr.
- Trial name
- NCT05922280
- Testing
- subtalar and talo-crural mobilization, International Working Group of the Diabetic Foot care guidelines
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Riphah International University
Angioplasty, Peripheral Arterial Disease
European All-comers' Multicentric Prospective REGISTRY on LUMINOR© Drug Eluting Balloon in the Superficial Femoral Artery and Popliteal Artery With 5 Years Follow-up.
The objective of this all-comers registry is to explore the safety, efficacy, and cost-efficiency of the LUMINOR© DEB in de-novo and restenotic-FP lesions.
- Conditions
- Angioplasty, Peripheral Arterial Disease, Drug-eluting Balloon, Femoral Artery
- Trial name
- LUMIFOLLOW (NCT04743180)
- Testing
- LUMINOR© Paclitaxel eluting balloon
- Where
- 15 sites in France
- Volunteers
- 500 people
- Sponsor
- iVascular S.L.U.
Arteriosclerosis, Peripheral Artery Disease
Durg Coated Balloon Angioplasty in Infrapopliteal Lesions
This study is a multicenter observational study designed to evaluate the the effectiveness and safety of drug-coated balloon (DCB) angioplasty for below the knee arterial lesions in patients critical with Limb Threatening…
- Conditions
- Arteriosclerosis, Peripheral Artery Disease, Chronic Limb Threatening Ischemia
- Trial name
- Act (NCT05620095)
- Testing
- drug-coated balloon
- Where
- 10 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology
Peripheral Vascular Disease, Peripheral Artery Disease
Prehabilitation for PAD Revascularization Patients
Patients undergoing elective revascularization of their peripheral artery disease will be randomized to a prehabilitation program or usual care prior to their scheduled procedure.
- Trial name
- NCT02767895
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Michigan
Peripheral Vascular Disease, Intermittent Claudication
Evaluation of Cilostazol in Combination With L-Carnitine
The purpose of this study is to see how safe and effective L carnitine taken with cilostazol is compared to placebo taken with cilostazol for people with intermittent claudication.
- Conditions
- Peripheral Vascular Disease, Intermittent Claudication, Peripheral Arterial Disease
- Trial name
- ECLECTIC (NCT00822172)
- Testing
- Levocarnitine tartrate, cilostazol
- Where
- 24 sites in United States
- Volunteers
- 164 people
- Sponsor
- Colorado Prevention Center
Peripheral Arterial Disease
SAFE (Sarpogrelate Anplone in Femoro-popliteal Artery Intervention Efficacy) Study
After endovascular treatment (EVT) for peripheral artery disease (PAD), dual antiplatelet therapy (DAAT) of aspirin (ASA) and clopidogrel are currently drug of choice to prevent occlusion.
- Trial name
- NCT02959606
- Testing
- Sarpogrelate SR 300mg, Clopidogrel
- Where
- South Korea
- Volunteers
- 272 people
- Sponsor
- Seoul National University Hospital
Diabetes, Type 1 Diabetes
The Role of South Asian vs European Origins on Circulating Regenerative Cell Exhaustion
ORIGINS-RCE is an observational, cross-sectional, two-arm study aimed at determining if an individual's ethnic origin influences the number of blood vessel-forming stem cells in the bloodstream.
- Conditions
- Diabetes, Type 1 Diabetes, Type 2 Diabetes, Ischemic Heart Disease
- Trial name
- ORIGINS-RCE (NCT05253521)
- Where
- 3 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Myocardial Infarction, Diabetes Mellitus, Type 2
Aerobic Training in Post-MI Patients With DPN
Cardiac rehabilitation (CR) is categorized by the American College of Cardiology "class IA recommendation" in the management of patients with cardiovascular disease (CVD) including post-myocardial infarction (MI) patients, who…
- Conditions
- Myocardial Infarction, Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
- Trial name
- NCT03913793
- Testing
- Exercise based-cardiac rehabilitation (EB-CR) program
- Volunteers
- 37 people
- Sponsor
- Yousra Hisham Abdel Fattah
Breast Cancer, Chronic Myeloproliferative Disorders
Blood Samples From Patients on a Clinical Trial to CINV During HSCT
RATIONALE: Studying samples of blood in the laboratory from patients with cancer may help doctors learn more about nausea and vomiting caused by cancer treatment.
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Leukemia
- Trial name
- NCT00900068
- Testing
- immunoenzyme technique, laboratory biomarker analysis, medical chart review
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- OHSU Knight Cancer Institute
Peripheral Artery Disease
BEETroot Juice to Reverse Functional Impairment in PAD
The BEET PAD Trial is a multi-centered double-blind randomized clinical trial designed to determine whether beetroot juice, compared to placebo, improves six-minute walk distance at four month follow-up in people with lower…
- Trial name
- BEET PAD (NCT05624125)
- Testing
- Beetroot juice
- Where
- 4 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Coronary Arteriosclerosis, Diabetes Mellitus, Type 2
Benefits Of Using Various Starting Doses Of Atorvastatin On Achievement Of Cholesterol Targets
European physicians tend to always use the lowest dose of statins to initiate therapy even in subjects who require large reductions in cholesterol.
- Conditions
- Coronary Arteriosclerosis, Diabetes Mellitus, Type 2, Cerebrovascular Accident, Dyslipidemia
- Trial name
- ACTFAST 2 (NCT00442325)
- Testing
- Atorvastatin (Lipitor)
- Where
- 32 sites in Greece, Hungary and 6 more
- Volunteers
- 595 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Peripheral Artery Disease
Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease
The investigators are doing this research study to find out if taking Metformin improves walking ability in patients with peripheral arterial disease (PAD).
- Trial name
- NCT01901224
- Testing
- Metformin 1000 mg
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Cancer
Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation.
- Trial name
- NCT00008359
- Testing
- caspofungin acetate, liposomal amphotericin B
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Drug Coated Balloon, Peripheral Arterial Disease
A Single Arm Trial to Evaluate the Safety and Efficacy of the Long (> 150mm) PasseoTM-18 LuxTM Drug-coated Balloon in the Treatment of Subjects With Infrainguinal Stenotic, Restenotic or Occlusive Lesions
This clinical trial will evaluate the study device, Passeo®-18 Lux® paclitaxel-releasing percutaneous transluminal angioplasty (PTA) balloon catheter for the treatment of new or recurring cholesterol-related blockages in the…
- Trial name
- LUX-PAD (NCT07385573)
- Testing
- Percutaneous Transluminal Angioplasty with the use of Passeo-18 Lux DCB
- Where
- 4 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- KANDO Research
Systemic Inflammatory Response Syndrome, Distributive Shock
Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status
The aim of this study is to determine the effects of fluid alternations, hemodynamic changes, mechanical ventilation, pharmacologic agents, positional changes, and comorbidities on the Peripheral Intravenous waveform Analysis…
- Conditions
- Systemic Inflammatory Response Syndrome, Distributive Shock, Hypotension and Shock, Decompensated Congestive Heart Failure
- Trial name
- PIVA (NCT03407287)
- Testing
- Peripheral Intravenous Analysis (PIVA), Standard of care invasive vascular monitoring, Standard noninvasive vascular monitoring
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Vanderbilt University Medical Center
Peripheral Arterial Disease, Venous Thormboembolism
VTE Incidence After Rivaroxaban + Aspirin or SAPT After Lower-limb Revascularization
Venous thromboembolism (VTE) has a high prevalence in patients with multiple comorbidities undergoing complex surgical procedures.
- Conditions
- Peripheral Arterial Disease, Venous Thormboembolism, Cardiovascular Diseases, Vascular Surgery Patient with PAD / Carotid Stenosis
- Trial name
- RESOLUTION (NCT06873321)
- Testing
- rivaroxaban 2.5 mg bid + aspirin 100 mg, clopidogrel 75 mg od for 3 months followed by aspirin 100 mg od for endovascular procedures or aspirin for open procedures
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Science Valley Research Institute
Vascular Diseases, Carotid Artery Diseases
Frailty in Vascular Patients Undergoing Surgery
An observational cohort study of the frailty of vascular surgery patients undergoing intervention and their outcomes.
- Conditions
- Vascular Diseases, Carotid Artery Diseases, Aneurysmal Disease, Peripheral Artery Disease
- Trial name
- NCT03668821
- Testing
- Questionnaire
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Imperial College London
Peripheral Vascular Disease
Tack Optimized Balloon Angioplasty (TOBA) Study
A multi-center, post-CE Mark study designed to evaluate the performance of the Intact Vascular Tack-IT Endovascular Stapler™ in subjects with vascular flaps (e.g.; post-angioplasty dissection) resulting from percutaneous…
- Trial name
- TOBA (NCT01663818)
- Testing
- Tack-It Endovascular Stapler
- Where
- Belgium
- Volunteers
- 138 people
- Sponsor
- Philips Clinical & Medical Affairs Global
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.