Clinical trials: PERIPHERAL VASCULAR DISEASE
Peripheral Vascular Diseases, Thrombosis
A Prospective Observational Registry of Peripheral Use of AngioJet Rheolytic Thrombectomy With Mid-Length Catheters
This registry collects observational data about how mid-length AngioJet catheters (ie XPEEDIOR and DVX models) are used in routine clinical practice.
- Conditions
- Peripheral Vascular Diseases, Thrombosis, Venous Thrombosis
- Trial name
- NCT00778336
- Volunteers
- 452 people
- Sponsor
- Boston Scientific Corporation
Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission
High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma
RATIONALE: Giving high doses of chemotherapy drugs, such as busulfan and cyclophosphamide, before a donor bone marrow transplant helps stop the growth of cancer cells.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a)
- Trial name
- NCT01177371
- Testing
- busulfan, cyclophosphamide, allogeneic bone marrow transplantation
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
Peripheral Arterial Disease, Endovascular Procedures
Short vs Long Duration Dual Antiplatelet Therapy in Patients Undergoing Lower Extremity Endovascular Revascularization
The primary objective of the trial is to evaluate short versus long duration dual antiplatelet therapy in patients undergoing lower extremity endovascular revascularization.
- Trial name
- NCT02433587
- Testing
- Aspirin, Clopidogrel
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Type 2 Diabetes Mellitus
Prevalence of Macrovascular Disease in Type 2 Diabetes Mellitus
The study aim is to establish a consecutive population of newly referred type 2 diabetes mellitus patients and among these to describe the degree of macrovascular disease by evaluating left ventricular systolic and diastolic…
- Trial name
- NCT00298844
- Where
- Denmark
- Volunteers
- 350 people
- Sponsor
- Odense University Hospital
Childhood Malignant Fibrous Histiocytoma of Bone, Sarcoma
Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery
RATIONALE: Celecoxib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Trial name
- NCT00450736
- Testing
- celecoxib, adjuvant therapy, radiation therapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
Femoropopliteal Artery Disease
Korean Multicenter Registry of INNOVA Stent for Femoropopliteal Artery Disease: (K-INNOVA Registry)
Prospective, single-arm, multi-center registry study A total of 150 subjects with femoropopliteal artery disease who meet all inclusion and exclusion criteria will be included.
- Trial name
- NCT02701816
- Testing
- innova stent (Boston scientific)
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
Peripheral Arterial Disease
DURABILITY+ : a Prospective, Multi-center, Controlled Study With the Everflex+ Stent in SFA Lesions
The objective of this study is to evaluate the immediate and long-term (up to 12 months) safety and effectiveness of primary stenting with the Protégé Everflex+ stent system for the treatment of superficial femoral artery (SFA)…
- Trial name
- DURABILITY+ (NCT01412463)
- Testing
- stent placement
- Where
- 3 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Flanders Medical Research Program
Vascular Diseases, Peripheral, Venous Insufficiency of Leg
The Study of Reducing Adverse Effects After Radiofrequency Ablation Combined With Sclerotherapy
The purpose of this study is to evaluate whether adding sulodexide to the patients with varicose veins who received radiofrequency ablation combined with sclerotherapy can reduce or improve the impact of adverse events。
- Conditions
- Vascular Diseases, Peripheral, Venous Insufficiency of Leg, Varicose Veins of Lower Limb
- Trial name
- NCT05654233
- Testing
- Sulodexide
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Foot Ulcers, Diabetic, Plantar Foot Pressure
Plantar Load Analysis of Neuropathic and Neuroischaemic Diabetes-Related Foot Ulceration
This single-centre observational case-control study investigates how peripheral arterial disease influences plantar load in people with diabetes who have recently healed a plantar foot ulcer.
- Conditions
- Foot Ulcers, Diabetic, Plantar Foot Pressure, Fat Pad Atrophy, Peripheral Arterial Disease
- Trial name
- PLANE-DFU (NCT07901478)
- Testing
- Pedar™ In-Shoe Plantar Pressure Measurement System, STAMPS 3D Digital Image Correlation System, Weight-Bearing Ultrasound of the Plantar Fat Pad
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Peripheral Vascular Disease
Atrium iCAST Iliac Stent Pivotal Study
Prospective, multicenter, non-randomized, single-arm registry to evaluate the safety and effectiveness of the iCAST Covered Stent System in the treatment of patients with symptomatic claudication or rest pain and angiographic…
- Trial name
- iCARUS (NCT00593385)
- Testing
- iCAST covered stent
- Where
- 25 sites in United States, Germany
- Volunteers
- 165 people
- Sponsor
- Atrium Medical Corporation
Peripheral Arterial Disease (PAD), Ankle Brachial Index
Automated ABPI in Peripheral Arterial Disease a Pilot Study
The aim of this pilot study is to investigate the diagnostic accuracy of two automated ABPI devices across the spectrum of PAD (asymptomatic PAD, suspected symptomatic PAD [IC; including mild moderate and severe IC based on the…
- Conditions
- Peripheral Arterial Disease (PAD), Ankle Brachial Index, Diagnostic Accuracy, Feasibility Studies
- Trial name
- AUTO-PAD (NCT07850349)
- Testing
- MESI mTablet, BlueDop vascular Expert (BlueDopVE)
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Sarpogrelate, Blood Viscosity
A Study to Compare the Effects of Sarpogrelate Sustained Release /Aspirin Combination Therapy Versus Aspirin on Blood Viscosity in the Patients With Peripheral Arterial Disease and Coronary Artery Disease
This study is to compare the effects of sarpogrelate sustained release /aspirin combination therapy versus aspirin on blood viscosity in the patients with peripheral arterial disease and coronary artery disease
- Conditions
- Sarpogrelate, Blood Viscosity, Peripheral Arterial Disease, Coronary Artery Disease
- Trial name
- NCT05730621
- Testing
- Sarpogrelate Sustained Release/Aspirin, Aspirin
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Yuhan Corporation
Peripheral Arterial Disease
Effect of a Hybrid Rehabilitation Program on Walking, Quality of Life & Cardiovascular Risk in People With PAD
Peripheral arterial disease (PAD), a disabling condition, affects 800,000 Canadians. People with PAD suffer from poor quality of life due to leg pain, which makes walking difficult. They also have a high risk of heart disease.
- Trial name
- HY-PAD (NCT03649204)
- Testing
- HY-PAD
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Drug/Agent Toxicity by Tissue/Organ, Leukemia
Growth Factor to Prevent Oral Mucositis in Patients With Hematologic Cancer
RATIONALE: Keratinocyte growth factor may prevent symptoms of mucositis in patients receiving radiation therapy and chemotherapy.
- Conditions
- Drug/Agent Toxicity by Tissue/Organ, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00004132
- Testing
- filgrastim, palifermin, cyclophosphamide
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Multiple Myeloma, Diffuse Large B-Cell Lymphoma (DLBCL)
Karyopharm Expanded Access Program for Selinexor
KEAP is an expanded access program designed to provide selinexor to eligible participants outside of a clinical trial before the drug has been given marketing approval by the country's regulatory agency or the drug is…
- Conditions
- Multiple Myeloma, Diffuse Large B-Cell Lymphoma (DLBCL), Sarcoma, Neuroglioblastoma
- Trial name
- KEAP (NCT07215832)
- Testing
- selinexor
- Sponsor
- Karyopharm Therapeutics Inc
Critical Limb Ischemia
Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia
This is an open-label, non-randomized, multi center, patient sponsored study of Adipose-Derived Stromal Cell (ASC) implantation via intramuscular injections in patients who have critical limb ischemia not amenable for…
- Trial name
- NCT02099500
- Testing
- Liposuction, Stem Cell Injection
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Peripheral Artery Disease
Cardiovascular Biomarkers in Peripheral Artery Disease.
Despite the best medical management, many patients with peripheral artery disease (PAD) who undergo lower extremity endovascular revascularization experience adverse cardiovascular outcomes and postoperative complications that…
- Trial name
- NCT05757258
- Where
- Italy
- Volunteers
- 207 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Peripheral Arterial Disease, Peripheral Vascular Diseases
BOLT Lithotripsy RESTORE ATK Trial
The RESTORE (ATK) above the knee study is a prospective, non- randomized, multi-center study for treatment of stenotic lesions with the Bolt Intravascular Lithotripsy System.
- Trial name
- RESTORE ATK (NCT05662787)
- Testing
- Intravascular Lithotripsy
- Where
- 11 sites in Austria, Croatia and 1 more
- Volunteers
- 97 people
- Sponsor
- Bolt Medical
Diabetes Mellitus, Type 1, Diabetic Retinopathy
Choroidal Blood Flow Changes During Dark/Light Transitions in Patients With Insulin-dependent Diabetes Mellitus (IDDM)
There is evidence from a variety of animal studies that choroidal blood flow is under neural control. Recent results in humans indicate that a light/dark transition is associated with a short lasting reduction in choroidal blood…
- Trial name
- NCT00718614
- Testing
- Light will be switched from 0.5µW/cm2/sr to 115µW/cm2/sr.
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Peripheral Arterial Occlusive Disease, Critical Limb Ischemia
Autologous BMMNC Combined With HA Therapy for PAOD
The purpose of this study is to evaluate the safety and efficacy of hyaluronan combined with autologous bone marrow mononuclear cells for the treatment of critical PAOD patients.
- Trial name
- NCT03214887
- Testing
- RV-P1501
- Where
- 2 sites in Taiwan
- Sponsor
- Academia Sinica, Taiwan
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