Clinical trials: PERIPHERAL VASCULAR DISEASE
Atrial Fibrillation, Peripheral Vascular Disease
Atrial Fibrillation Registry for Ankle-brachial Index Prevalence Assessment: Collaborative Italian Study.
Atrial fibrillation (AF) is the most common sustained dysrhythmia encountered in clinical practice in North America and Europe, accounting for approximately one-third of all hospitalizations for a cardiac rhythm abnormality.
- Trial name
- ARAPACIS (NCT01161251)
- Where
- 2 sites in Italy
- Volunteers
- 2,027 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Peripheral Arterial Disease
Blood Flow Quantification Near Stented SFA Lesions Using Ultrasound Velocimetry
Peripheral arterial disease (PAD) in the lower extremity is the third leading cause of atherosclerotic cardiovascular morbidity. Endovascular treatment has become the principal surgical strategy in femoro-popliteal lesions.
- Trial name
- EchoPIV in SFA (NCT04934501)
- Testing
- High-frame-rate contrast-enhanced ultrasound measurements (echoPIV), Computed tomography angiography (CTA) scan
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Peripheral Artery Disease, Polyvascular Disease
Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial)
Patients with atherosclerotic peripheral artery disease often have combined coronary artery disease or cerebral artery disease and show high rates of cardiovascular mortality and morbidities.
- Trial name
- NCT06231966
- Testing
- Combination therapy of high-intensity dose rosuvastatin and ezetimibe, Rosuvastatin monotherapy for treat-to-target
- Where
- South Korea
- Volunteers
- 2,462 people
- Sponsor
- Yonsei University
Thoracic Outlet Syndrome
Mobilization With Movement on Pain, Function, and Quality of Life in Patients With Thoracic Outlet Syndrome
This study will investigate whether adding Mobilization With Movement (MWM) to a standardized rehabilitation program improves arm, shoulder, and hand function in adults with chronic neurogenic thoracic outlet syndrome (nTOS)…
- Trial name
- NCT05917756
- Testing
- Mobilization with Movement (MWM), Standardized Rehabilitation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ahram Canadian University
Diabetes Mellitus Type 2, Cardiovascular Diseases
PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
To evaluate the proportion of diabetic mellitus patients with CV events as measured by HEMOTAG.
- Conditions
- Diabetes Mellitus Type 2, Cardiovascular Diseases, Coronary Artery Disease, Cerebrovascular Disease
- Trial name
- PRIZETAG (NCT06567795)
- Testing
- Hemotag
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- Aventusoft, LLC.
Atherosclerosis, Intermittent Claudication
Patient Acceptance of Whole Body Magnetic Resonance Angiography
Investigation of how the patients experience whole body MRA. After the WB-MRA the patients will fill in a questionnaire, that contains questions about the WB-MRA procedure and how the patient felt during the examination.
- Conditions
- Atherosclerosis, Intermittent Claudication, MRI
- Trial name
- NCT00556101
- Testing
- Whole body magnetic resonance angiography
- Where
- Denmark
- Volunteers
- 81 people
- Sponsor
- Copenhagen University Hospital at Herlev
Limb Salvage Rates With Endovascular Therapy
Endovascular Limb Salvage in Trinidad and Tobago
The purpose of this study was to investigate limb salvage rates in patients with critical limb ischemia after endovascular revascularization.
- Trial name
- NCT05547022
- Testing
- Endovascular revascularisation
- Where
- Trinidad and Tobago
- Volunteers
- 157 people
- Sponsor
- Naveen Seecheran
Intermittent Claudication, Peripheral Vascular Diseases
Objective Evaluation of Proximal Ischemia
The whole study is divided in 4 parallel protocols. The first protocol estimates the reliability of the technique through test-retest recordings.
- Trial name
- NCT00152737
- Testing
- Exercise test with Transcutaneous oxygene pressure, Ankle and arm pressure values
- Where
- France
- Volunteers
- 165 people
- Sponsor
- University Hospital, Angers
Proteus Syndrome, PIK3CA-Related Overgrowth Spectrum (PROS)
Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies
ARQ 092 is being investigated for patients with overgrowth diseases and/or vascular anomalies with genetic alterations of the PI3K/AKT pathway and may be available for patients who are ineligible for an ongoing ARQ 092 clinical…
- Conditions
- Proteus Syndrome, PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorders
- Trial name
- NCT03317366
- Testing
- ARQ 092
- Sponsor
- ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
Chronic Lower Limb Ischemia, Peripheral Athero Obstructive Disease
Paclitaxel Eluting Stent in Long SFA Obstruction: A Prospective, Randomized Comparison With Bypass Surgery
Chronic lower limb ischemia due to atherosclerosis causes significant morbidity especially in elderly: the prevalence of asymptomatic obstructive peripheral atherosclerosis among 40-74 old is 4-22%.
- Conditions
- Chronic Lower Limb Ischemia, Peripheral Athero Obstructive Disease, Critical Ischemia, Claudication
- Trial name
- finnptx (NCT01450722)
- Testing
- bypass surgery, stent placement, stent placement
- Where
- Finland
- Volunteers
- 400 people
- Sponsor
- Kuopio University Hospital
Peripheral Arterial Disease
Investigation of Safety, Pharmacokinetics and Pharmacodynamics of Different Doses of BIWH 3 in Patients With Chronic Critical Limb Ischaemia
The primary aim of this trial was to investigate the safety of a 6 hour intraarterial infusion of BIWH 3 (pyro-Glu-rhMCP-1) in patients with severe peripheral arterial occlusive disease (PAOD) and chronic Critical Limb Ischaemia…
- Trial name
- COINART-1 (NCT02215824)
- Testing
- BIWH 3
- Volunteers
- 7 people
- Sponsor
- Boehringer Ingelheim
Cardiovascular Diseases, Heart Diseases
Incidence of Diabetes and Cardiovascular Disease in Mexican Americans
To determine the incidence of type II diabetes and cardiovascular disease among Mexican-American and non-Hispanic whites in a 15 to 24 year follow-up of the San Antonio Heart Study 1 participants.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Angina Pectoris
- Trial name
- NCT00005205
- Sponsor
- The University of Texas Health Science Center at San Antonio
Diabetic Foot Ulcer
Placental Cells for Diabetic Foot Ulcers
The purpose of this research study is to test the safety of placental stem cells to treat non-healing diabetic foot ulcers.
- Trial name
- NCT07686094
- Testing
- Placenta Stem Cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
Complications
Standard Length Catheters vs Long Catheters in Peripheral Vein Cannulation.
The Long and Short is a prospective, randomized, controlled, open label trial to test the complications of different device for peripheral vein cannulation, standard length (about 5 cm in length) and long catheter (about 12 cm in…
- Trial name
- Long&short (NCT01917253)
- Testing
- Standard Device for peripheral vein cannulation, Long Catheters for peripheral vein cannulation
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- ASL TO2 Torino
Peripheral Arterial Disease
Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone in Europe
The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages.
- Trial name
- AMBITION BTK (NCT07472439)
- Testing
- Auryon Atherectomy System, Balloon Angioplasty
- Volunteers
- 50 people
- Sponsor
- Angiodynamics, Inc.
Stroke
Autologous Hematopoietic Stem Cell Transplantation in Ischemic Stroke
The purpose of this study is to evaluate the safety and efficacy of autologous peripheral hematopoietic stem cell transplantation in ischemic stroke.
- Trial name
- AHSCTIS (NCT01518231)
- Testing
- autologous hematopoiesis stem cell transplantation, Aspirin, Warfarin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhejiang Hospital
Peripheral Arterial Disease
Exploring the Exercise Fear Experiences of Patients With Peripheral Arterial Disease: A Qualitative Study
This study explored the exercise fear experience of patients with lower extremity arteriosclerosis obliterans. We conducted qualitative interviews and identified four core themes contributing to patients' fear of physical…
- Trial name
- NCT07877129
- Testing
- a descriptive qualitative design
- Where
- China
- Volunteers
- 18 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Thoracic Outlet Syndrome
Thoracic Outlet Syndrome: Case Reports and Analysis With Ultrasound Imaging
Thoracic outlet syndrome is caused by compression of the brachial plexus, in most cases under the pectoralis minor muscle in the infraclavicular region of the shoulder.
- Trial name
- NCT01196637
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- EMG Labs of Arizona Arthritis & Rheumatology Associates
Atherosclerosis, Coronary Disease
Natural History of Peripheral Arterial Disease
The Veterans Administration Patient Study examined the progression of peripheral arterial disease (PAD) in patients with large vessel PAD or isolated small vessel PAD.
- Conditions
- Atherosclerosis, Coronary Disease, Arterial Occlusive Diseases, Peripheral Vascular Diseases
- Trial name
- NCT00005254
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Peripheral Arterial Disease
Feasibility Clinical Trial of the Cardio Flow Orbital Atherectomy System to Treat Peripheral Artery Disease (PAD)
This trial is a First in Human early feasibility study of a novel atherectomy device to treat peripheral artery disease. The trial is a prospective, single arm design that will enroll 10 patients at 1 - 2 sites.
- Trial name
- FAST (NCT03365154)
- Testing
- Cardio Flow FreedomFlow™ Orbital Atherectomy System treatment, Balloon Angioplasty
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Cardio Flow, Inc.
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