Clinical trials: PERIPHERAL VASCULAR DISEASE
Peripheral Vascular Disease, Coronary Artery Disease
Angio-Seal Evolution Device Registry
Collect data on the use of the Angio-Seal Evolution Device in diagnostic and interventional patient populations.
- Conditions
- Peripheral Vascular Disease, Coronary Artery Disease, Peripheral Artery Disease, Arterial Occlusive Disease
- Trial name
- NCT00817349
- Where
- 10 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- Abbott Medical Devices
Vascular Disease, Peripheral, Amputation
Vascular Amputee Physical Performance Qualitative (VAmPP-Q) Study
Background: Peripheral arterial disease (PAD) is the main cause of amputation to the lower limb within the UK, affecting over 20% of adults older than 70 years.
- Conditions
- Vascular Disease, Peripheral, Amputation, Physical Disability
- Trial name
- VAmPP-Q (NCT05860764)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Leicester
Peripheral Arterial Disease
Magnesium Oral Supplementation to Reduce Pain Inpatients With Severe Peripheral Arterial Occlusive Disease
Magnesium exerts analgesic effects in several animal pain models and in patients affected by acute postoperative pain and chronic pain of neuropathic origin.
- Trial name
- NCT02455726
- Testing
- Magnesium oxide, Fructose, Oxycodone
- Volunteers
- 150 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Vasodilation, Diabetes Mellitus, Type 2
Impact of Regional Vibration Application and Flow Mediated Dilation on Brachial Artery Hemodynamics
Application of vibration has been previously shown to affect tissue perfusion and utilized in different branches of medicine. Little is known about the acute impact of vibration application on peripheral artery hemodynamics.
- Trial name
- VMD (NCT05492071)
- Testing
- Local Vibration Application Following Flow Mediated Dilation, Flow mediated dilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Peripheral Vascular Diseases
Screening DIVA - Diffuse Vascular Disease
Primary Objective: To investigate the value of the Edinburgh Claudication Questionnaire (ECQ) against the ankle-brachial index (ABI) in Canadian patients mainly followed in general practice, with documented acute coronary…
- Trial name
- NCT01076738
- Where
- Canada
- Volunteers
- 2,233 people
- Sponsor
- Sanofi
Femoral Artery Stenosis, Popliteal Artery Stenosis
MDT-2113 Drug-Eluting Balloon vs. Standard PTA for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery and/or Proximal Popliteal Artery
The purpose of this trial is to assess the safety and efficacy of MDT-2113 for the interventional treatment of de novo and non-stented restenotic lesions in the superficial femoral artery (SFA) and the proximal popliteal artery…
- Conditions
- Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- MDT-2113 SFA (NCT01947478)
- Testing
- MDT-2113 Drug-Eluting Balloon, Standard angioplasty balloon
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Medtronic Endovascular
Hypertension
A Trial of Telmisartan Prevention of Cardiovascular Disease
The present research is conducted as a randomized, parallel-group, controlled, open study (using the PROBE method) to primarily verify the effects on various biomarkers in high-risk hypertensive patients treated with ARB…
- Trial name
- ATTEMPT-CVD (NCT01075698)
- Testing
- Non-ARB (standard therapy), ARB (Telmisartan)
- Where
- Japan
- Volunteers
- 1,228 people
- Sponsor
- Kumamoto University
Peripheral Artery Disease
Post-operative Treatment of Diabetic Peripheral Arterial Disease Guided by Platelet Reactivity Unit
To compare the effect of PRU(platelet (P2Y12) reaction units)-guided treatment on the change in 1. time of initial leg pain and time of termination of exercise test by pain, evaluated on the graded stationary bicycle test, 2.
- Trial name
- NCT02762864
- Testing
- platelet (P2Y12) reaction units, ticagrelor, Comparator
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Peripheral Arterial Disease
SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs
A research project capturing experiences of patients with critical limb threatening ischemia, with the ultimate goal of setting new standards for diagnosing, describing detailed patient-centered outcomes, and evaluating the…
- Trial name
- SCOPE-CLI (NCT04710563)
- Where
- United States
- Volunteers
- 458 people
- Sponsor
- Yale University
Vascular Disease, Peripheral, Thromboprophylaxis
Heparin-Binding Protein and Heparins
Heparin-Binding protein is a protein from primary and secretory granluae of white blood cells. It is released when white blood cells become activated and has been advocated as a biomarker for sepsis.
- Conditions
- Vascular Disease, Peripheral, Thromboprophylaxis, Cardiovascular Diseases
- Trial name
- HepHep (NCT04146493)
- Testing
- Blood samples for Heparin-binding protein measurement
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Halla Halldorsdottir
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Foot Ulcer, Diabetic
Approaches to Foot Complication Prevention: A Survey of Diabetes Educators
The purpose of the survey is to assess the knowledge base, role in management, and resources available to diabetes educators regarding foot complication prevention within a variety of healthcare settings.
- Trial name
- NCT04400344
- Testing
- No intervention
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Podimetrics, Inc.
Fabry Disease, Neuropathic Pain
Safety and Efficacy of Gabapentin for Neuropathic Pain in Fabry Disease
The purpose of this study is to determine efficacy of gabapentin vs. placebo at controlling peripheral neuropathic pain in patients with Fabry disease, and reducing their use of opioid analgesics.
- Trial name
- NCT01588314
- Testing
- Gabapentin
- Where
- United States
- Sponsor
- University of Minnesota
Peripheral Arterial Disease, Common Femoral Artery Stenosis
Endovascular Treatment of Primary Common FEmoral Artery atheroSclerotic Disease wiTh IntraVAscular Litothripsy
Prospective, nonrandomized, multicenter, national, multidisciplinary, real-world data collection with the aim to evaluate the short-term safety and efficacy of intravascular lithotripsy in the treatment of steno-obstructive…
- Conditions
- Peripheral Arterial Disease, Common Femoral Artery Stenosis, Common Femoral Artery Occlusion, Critical Limb-Threatening Ischemia
- Trial name
- FESTIVAL (NCT05821829)
- Testing
- Intravascular litothripsy (IVL)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Pisa
Peripheral Arterial Disease, Claudication, Intermittent
Safety and Efficacy of Atherectomy on VasculaR Functions
Interventional strategies aim to restore tissue perfusion. However, despite the simple reopening of a narrowed artery they affect endothelial function, perpetuating dysfunctional vascular homeostasis.
- Trial name
- SAVioR (NCT04092972)
- Testing
- Atherectomy, POBA and DCB
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Critical Limb Ischemia
Impact of Critical Limb Ischemia on Long Term Cardiac Mortality in Diabetic Patients Undergoing Percutaneous Coronary Revascularization
Prospective cohort study of consecutive diabetic patients undergoing percutaneous coronary intervention (PCI) in whom development of critical limb ischemia was prospectively assessed by a dedicated diabetic foot clinic.
- Trial name
- NCT01676519
- Testing
- PCI
- Where
- Italy
- Volunteers
- 764 people
- Sponsor
- Ospedale San Donato
Permanent Atrial Fibrillation, Venous Thrombosis
Vascular CalcIfiCation and sTiffness Induced by ORal antIcoAgulation
The VICTORIA Study (Vascular CalcIfiCation and sTiffness induced by ORal antIcoAgulation) is a comparative, parallel, prospective, controlled and randomized study of the structural and functional impact of rivaroxaban versus…
- Conditions
- Permanent Atrial Fibrillation, Venous Thrombosis, Pulmonary Embolism, Anticoagulation Treatment at Least > or = to 12-month
- Trial name
- VICTORIA (NCT02161965)
- Testing
- Rivaroxaban, Fluindione, Warfarin
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Angers
Critical Limb Ischemia, Peripheral Arterial Disease
Cryopreserved Saphenous Vein Allograft in Patients With Critical Limb Ischemia for Peripheral Revascularization
The objective Study is to evaluate the short- and long-term clinical outcomes of patients receiving the CryoVein cryopreserved saphenous vein allograft (CVA) as their primary open bypass conduit to assess if there is a…
- Trial name
- LIMBSAVE (NCT01799811)
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- CryoLife, Inc.
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Multiple Myeloma and Plasma Cell Neoplasm
Peripheral Stem Cell Transplantation Plus Combination Chemotherapy in Treating Patients With Multiple Myeloma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Trial name
- NCT00003399
- Testing
- carmustine, cisplatin, cyclophosphamide
- Where
- United States
- Sponsor
- University of Maryland, Baltimore