Clinical trials: PERIPHERAL VASCULAR DISEASE
Aspirin Resistance
Aspirin Resistance and Prognosis of Patients With Critical Limb Ischaemia
Acetylsalicylic acid (Aspirin, ASA) is the most widely prescribed drug used in primary and secondary prevention of cardiovascular disease.
- Trial name
- Aspirine (NCT01104441)
- Where
- 2 sites in France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Limoges
Peripheral Vascular Disease, Intermittent Claudication
Balloon Angioplasty vs. Cutting Balloon Angioplasty of Femoropopliteal Arteries- a Randomized Controlled Trial
The purpose of this study to compare balloon angioplasty (PTA) vs. cutting balloon angioplasty (CB-PTA) in terms of patency and postintervention inflammation in peripheral artery disease.
- Conditions
- Peripheral Vascular Disease, Intermittent Claudication, Atherosclerosis, Angioplasty
- Trial name
- NCT00437905
- Testing
- angioplasty
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Phlebitis
Removal Peripheral Intravenous Catheters According to Clinical Signs or Every 96 Hours: A Non Inferiority Study
This is a two-centers, open label, prospective, randomized, noninferiority controlled trial with cost-effectiveness analysis to verify if is non inferior to remove peripheral intravenous catheter according to clinical signs in…
- Trial name
- ResPeCt (NCT02568670)
- Testing
- clinical signs
- Where
- Brazil
- Volunteers
- 1,305 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Critical Limb Ischemia (CLI)
Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization
This will be a randomized, placebo-controlled, parallel group, multicenter, Phase III study.The study aims to evaluate the Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects…
- Trial name
- NCT03006770
- Testing
- PLX-PAD
- Where
- 57 sites in United States, Bulgaria and 7 more
- Volunteers
- 213 people
- Sponsor
- Pluristem Ltd.
Multiple Myeloma, Amyloidosis
Vinorelbine and Gemcitabine in Myeloma
The purpose of this study is to determine whether the efficacy of gemcitabine is comparable with the efficacy of the standard chemotherapy with vinorelbine for mobilization of autologous stem cells in myeloma patients
- Trial name
- ViGeM (NCT02791373)
- Testing
- Vinorelbine, Gemcitabine
- Where
- Switzerland
- Volunteers
- 136 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Peripheral Artery Disease
Stents Post-dilation With DCB or POBA in Femoropopliteal Arteries
To compare the efficacy and safety of stent angioplasty with Orchid 035 Drug Coated Dilatation (DCB) and Plain Old Balloon Angioplasty (POBA) for post-dilatation for long (>10cm) femoropopliteal chronic total occlusion.
- Trial name
- SFPA (NCT03791970)
- Testing
- Orchid 035 DCB Catheter, POBA Catheter
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Peripheral Intravenous Vein Catheter Phlebitis, Intravenous Infection
Evaluating the Role of the Guidewire in Peripheral Intravenous Access
This study is to demonstrate that the control ultralong intravenous catheter without the guide wire is equivalent to the experimental catheter with the guide wire.
- Trial name
- NCT04949854
- Testing
- B.Braun 6.35 cm 20 Gauge ultralong intravenous catheter, B.D Accucath 5.71 cm 20 Gauge ultralong intravenous catheter
- Where
- United States
- Sponsor
- Corewell Health East
Acute Vestibular Syndrome, Vertigo
Quantitative Eye Movement Measurements in Patients with Acute Vestibular Syndrome
BACKGROUND: A chief complaint of acute vertigo/dizziness is related to about 2.1-7.1% of all emergency department (ED) visits. About 25% of all patients with acute prolonged vertigo meeting diagnostic criteria of AVS (acute…
- Conditions
- Acute Vestibular Syndrome, Vertigo, Stroke Acute, Acute Unilateral Vestibulopathy (AUV)
- Trial name
- NCT06668857
- Testing
- video-oculography
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexander Tarnutzer
Peripheral Artery Disease
BRight Pharmacokinetic Study
The BRight PK Study is a prospective, single-arm, open-label, non-blinded, non-randomized study, which goal is to assess the pharmacokinetic profile of the BRight drug-coated balloon at different time points after the balloon…
- Trial name
- NCT06065345
- Testing
- BRight DCB
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Biotronik CRC Inc.
Stroke, Acute, Vertigo
vHIT Testing for Presentation of Dizziness at a Comprehensive Stroke Center
The purpose of this study is to evaluate the sensitivity and specificity of the video head impulse test (vHIT) device, when implemented in the acute ED setting to identify acute ischemic stroke or central pathology vs peripheral…
- Conditions
- Stroke, Acute, Vertigo, Vertigo, Peripheral, Dizziness
- Trial name
- NCT06038175
- Testing
- Video Head Impulse Testing, Standard of care neurologic evaluation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Autologous Hematopoietic Stem Cell Transplant Recipient, Loss of Chromosome 17p
Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma
RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving chemotherapy drugs, such as fludarabine phosphate and melphalan, and total marrow irradiation before a donor…
- Conditions
- Autologous Hematopoietic Stem Cell Transplant Recipient, Loss of Chromosome 17p, Plasma Cell Leukemia, Recurrent Plasma Cell Myeloma
- Trial name
- NCT01163357
- Testing
- bortezomib, fludarabine phosphate, melphalan
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- City of Hope Medical Center
Critical Limb Ischemia
A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical Ischemia
Once the patients are identified that have a full thickness wound on a limb clearly identified as having critical limb ischemia, these patients will be evaluated.
- Trial name
- NCT00760357
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Peripheral Vascular Disease
Comparison of the SUpera® PERipheral System in the Superficial Femoral Artery
This is a prospective, multicenter, non-randomized, single arm, pivotal trial. The main objective of this study is to demonstrate the safety and effectiveness of the IDev SUPERA® Nitinol Stent System in treating subjects with…
- Trial name
- SUPERB (NCT00933270)
- Testing
- SUPERA® Nitinol Stent System
- Where
- 49 sites in United States
- Volunteers
- 325 people
- Sponsor
- Abbott Medical Devices
Peripheral Arterial Disease
The Role of HSP90 in Peripheral Vascular Lesions of Diabetic Atherosclerosis
Diabetic foot disease with a global incidence of about 6% is one of the most serious complications of diabetes, which brings great pain and economic burden to patients.In China, the incidence rate is 8.1%, and the amputation rate…
- Trial name
- rhsppvlda (NCT04787770)
- Testing
- non-intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD)
VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN)
The goal of this study is to understand and compare an alternative model of care in comparison to the usual model of care in include male and female participants ≥18 years of age with a history of ASCVD (hear and blood vessels…
- Conditions
- Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD), Cerebrovascular Disease, Peripheral Arterial Disease (PAD)
- Trial name
- v-ASCERTAIN (NCT05834673)
- Testing
- SMS messages, Telephone-based support calls, GP Education
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Monash University
Diabetic Foot Ulcer, Peripheral Neuropathy
External Shoe Lift to Improve Healing and Adherence in Patients With Diabetic Foot Ulcers
Previous researches hipothesize that imposed limb-length discrepancies may discourage adherence in patients with active diabetic foot ulcer and using offloading devices.
- Conditions
- Diabetic Foot Ulcer, Peripheral Neuropathy, Treatment Adherence and Compliance
- Trial name
- NCT04117269
- Testing
- External shoe lift
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Universidad Complutense de Madrid
Leukemia, Lymphoma
Chemotherapy Plus Donor White Blood Cell Infusion in Treating Patients With Relapsed Hematologic Cancer Following Donor Peripheral Stem Cell Transplantation
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. White blood cells from donors may be able to prevent graft-versus-host disease in patients with hematologic…
- Conditions
- Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
- Trial name
- NCT00005946
- Testing
- filgrastim, therapeutic allogeneic lymphocytes, cyclophosphamide
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
Postoperative Delirium (POD), Peripheral Arterial Disease
Effect of Preoperative Ultrasound-Guided Stellate Ganglion Block on Postoperative Delirium in Older Adults Undergoing Elective Peripheral Endovascular Intervention
This randomized controlled trial will evaluate whether preoperative ultrasound-guided stellate ganglion block reduces the incidence of postoperative delirium in adults aged 60 years or older undergoing elective peripheral…
- Trial name
- NCT07848113
- Testing
- ropivacaine
- Volunteers
- 168 people
- Sponsor
- Assiut University
Breast Cancer, Chronic Myeloproliferative Disorders
Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining chemotherapy and peripheral stem cell transplantation with biological therapy may kill more cancer…
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Kidney Cancer
- Trial name
- NCT00003408
- Testing
- aldesleukin, recombinant interferon alfa, sargramostim
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cancer Treatment Centers of America