Clinical trials: PET/MRI
Male Breast Cancer, Stage II Breast Cancer
FDG PET and DCE-MRI in Predicting Response to Treatment in Patients With Breast Cancer
This clinical trial studies fludeoxyglucose F 18 (FDG) positron emission tomography (PET) and dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI) in predicting response to treatment in patients with breast cancer.
- Conditions
- Male Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer
- Trial name
- NCT01931709
- Testing
- fludeoxyglucose F 18, positron emission tomography, dynamic contrast-enhanced magnetic resonance imaging
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Washington
Glioblastoma, Malignant Glioma
18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy
This phase II trial studies how well fluorodopa F 18-positron emission tomography/magnetic resonance imaging scan (18F-DOPA-PET/MRI) works in imaging elderly patients with newly diagnosed grade IV malignant glioma or glioblastoma…
- Trial name
- NCT03778294
- Testing
- Computed Tomography, Fluorodopa F 18, Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Mayo Clinic
Prostate Cancer
PSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study
The goal of this study is to investigate the feasibility and toxicity of using prostate-specific membrane antigen-positron emission tomography (PSMA-PET) and multi-parametric magnetic resonance imagining (mpMRI) with PET-MR…
- Trial name
- NCT04176497
- Testing
- 68Ga-HBED-CC-PSMA
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Prostate Cancer
Pretreatment Staging of High-Risk Prostate Cancer With 18F-Fluciclovine PET/MRI
There is great need for improved preoperative imaging in men with high-risk prostate cancer. Investigators propose to develop and validate an optimized simultaneous PET/MRI protocol for local, regional and whole body preoperative…
- Trial name
- NCT03264456
- Testing
- [18F] Fluciclovine PET/MRI, [18F] fluciclovine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Alabama at Birmingham
Subjects With Clinical Indication for PET/CT
Clinical Evaluation of an Integrated PET/MRI System
The investigational PET/MRI scanner, including attenuation correction method, is capable of producing diagnostic quality images and appropriate device functionality per user feedback.
- Trial name
- PET/MR_ZURICH (NCT02071706)
- Testing
- PET/MRI system
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- GE Healthcare
Kidney Neoplasms, Carcinoma, Renal Cell
Evaluating Sunitinib Therapy in Renal Cell Carcinoma Using F-18 FDG PET/CT and DCE MRI
To learn whether Flourine-18 Fluoro-deoxi-glucose positron emission tomography / computed tomography (F-18 FDG PET/CT) and dynamic contrast enhanced magnetic resonance imaging (DCE MRI) are better predictors of response to…
- Conditions
- Kidney Neoplasms, Carcinoma, Renal Cell, Kidney (Renal Cell) Cancer
- Trial name
- NCT00537056
- Testing
- FDG PET CT, DCE MRI, F-18 Fluoro-deoxi-glucose
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Stanford University
Prostate Carcinoma
68Ga-DOTA-Bombesin PET/MRI in Imaging Patients With Prostate Cancer
This clinical trial studies the use of gallium-68 (68Ga)-DOTA-Bombesin as the imaging agent for positron emission tomography (PET)/magnetic resonance imaging (MRI), collectively PET-MRI, in patients with prostate cancer.
- Trial name
- NCT02440308
- Testing
- 68Ga-DOTA-Bombesin, Magnetic Resonance Imaging (MRI) scan, Positron Emission Tomography (PET) scan
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Low Back Pain, Back Pain With Radiation
Evaluating the Role of Neuroinflammation in Low Back Pain
In this research, the study team will use brain imaging to evaluate the presence of neuroinflammation in the brains and spinal cords of patients with low back pain.
- Conditions
- Low Back Pain, Back Pain With Radiation, Back Pain Without Radiation, Back Pain Lower Back Chronic
- Trial name
- IGNITE (NCT03106740)
- Testing
- Minocycline Hydrochloride 100mg Capsule, Magnetic Resonance-Positron Emission Tomography Imaging
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marco Loggia
Prostate Cancer
ZD4054 With Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) for Prostate Cancer
The purpose of this research study is to assess the effects of ZD4054 on prostate cancer that has spread to the bones by using new imaging techniques.
- Trial name
- NCT01119118
- Testing
- ZD4054
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison
Prostate Cancer
11C- and 18F-Choline PET/MR Imaging for Prostate Cancer
This phase II trial studies how well 11C-choline (carbon C 11 choline) and 18F-choline (fluorine F 18 choline) positron emission tomography/magnetic resonance (PET/MR) imaging works in diagnosing patients with unfavorable…
- Trial name
- NCT02397408
- Testing
- Carbon C 11 Choline, Fluorine F 18 Choline, Positron Emission Tomography (PET) / Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, San Francisco
Major Depressive Disorder (MDD), History of Childhood Sexual Abuse (CSA)
An Investigation of Early Life Stress and Depression
The purpose of this study is to investigate brain pathways within adult females (with a history of CSA that occurred between the ages of 5-14) with and without a current diagnosis of major depressive disorder (MDD).
- Trial name
- NCT01701258
- Testing
- Amisulpride
- Where
- 2 sites in United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depression
Advancing Personalized Antidepressant Treatment Using PET/MRI
Despite current medications, morbidity and mortality of Major Depressive Disorder (MDD) remain high. According to the World Health Organization, MDD affects 121 million people worldwide, and is projected to be the second leading…
- Trial name
- NCT02623205
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Stony Brook University
Bipolar Disorder, Bipolar Depression
PET and MRI Brain Imaging of Bipolar Disorder
The primary aims of this study are to: 1. Quantify serotonin transporter (5-HTT) binding potential (BP) in vivo in bipolar disorder patients (BPD) during a major depressive episode (MDE). 2.
- Conditions
- Bipolar Disorder, Bipolar Depression, Unipolar Depression
- Trial name
- NCT01880957
- Testing
- Lithium, Lamotrigine
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Recurrent Glioblastoma
Bevacizumab w / Temozolomide PET & Vascular MRI For GBM
This research study is exploring how the blood vessels in the participant's tumor change from treatment with bevacizumab, and how these changes affect the way their tumor absorbs temozolomide (TMZ).
- Trial name
- NCT01987830
- Testing
- MRI-PET, TMZ-PET
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Hepatic Malignancies
Comparison of Yttrium-90 Absorbed Doses Using PET/CT Versus PET/MR Imaging for Hepatic Malignancies
The purpose of this study is to compare the results of positron emission tomography/computer tomography (PET/CT) to positron emission tomography/magnetic resonance imaging (PET/MRI) to help determine any added advantage of one…
- Trial name
- NCT04332419
- Testing
- PET/CT, PET/MR, SIRT with Y-90
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Case Comprehensive Cancer Center
Low Back Pain
FDG PET/MRI Evaluation of Facet Joint Pain
Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints.
- Trial name
- NCT02921490
- Testing
- FDG PET/MR examination.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Glioma
Measuring Fatty Acid Oxidation in Gliomas Using 18F-FPIA PET/MRI
Glioma is the most common primary malignant brain tumour in adults and has an extremely poor prognosis. The aim of this study is to quantify the degree of early step fatty acid oxidation in gliomas as imaged by 18F-FPIA PET/MRI…
- Trial name
- NCT04097535
- Testing
- PET/MRI
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Imperial College London
Parkinson's Disease
Amyloidopathy, Cholinopathy, Dopamine Responsiveness and Freezing of Gait in PD
Early stage Parkinson disease (PD) is characterized by a 'honeymoon' phase in terms of responsiveness of motor symptoms, including gait, to dopaminergic pharmacotherapy.
- Trial name
- FOG (NCT03647137)
- Testing
- Detailed motor testing, including FoG, in PD subjects
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- VA Office of Research and Development
Childhood Cancer
PET/MRI and PET/CT in Diagnosing Younger Patients With Cancer
This pilot clinical trial studies how well positron emission tomography (PET)/magnetic resonance imaging (MRI) works compared to PET/computed tomography (CT) in diagnosing younger patients with cancer.
- Trial name
- NCT02287636
- Testing
- fludeoxyglucose F 18, positron emission tomography, computed tomography
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Case Comprehensive Cancer Center
Endometriosis
Evaluation of Endometriosis With 18F-fluoroestradiol PET / MRI
Purpose: The primary objective is to evaluate the sensitivity and specificity of 18F-fluoroestradiol (FES) PET/MRI for evaluating endometriosis.
- Trial name
- NCT04382911
- Testing
- 18F-fluoroestradiol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Chapel Hill