Clinical trials: PET / CT
Advanced Adult Primary Liver Cancer, Liver Metastases
Pilot Study to Assess Lung Shunting of Yttrium-90 Microspheres Using PET/CT
This pilot clinical trial studies positron emission tomography (PET)/computed tomography (CT) in finding beads after Yttrium-90 bead therapy in patients with primary liver cancer or cancer that has spread to the liver…
- Conditions
- Advanced Adult Primary Liver Cancer, Liver Metastases, Localized Unresectable Adult Primary Liver Cancer, Recurrent Adult Primary Liver Cancer
- Trial name
- NCT02119065
- Testing
- positron emission tomography, computed tomography
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Cincinnati
Healthy Volunteers (HV)
An Open-Label PET/CT Imaging Study to Evaluate Brain Serotonin Transporter (SERT) Occupancy Following Single-Dose Administration of LG-0317 Tablets in Healthy Participants
The purpose of the study is to evaluate brain serotonin transporter (SERT) receptor occupancy (RO) following single oral doses of LG-0317 tablets in healthy male participants; and to explore the pharmacokinetic/pharmacodynamic…
- Trial name
- NCT07708428
- Testing
- Cohort 1: LG-0317 20 mg, Cohort 1: LG-0317 40 mg, Cohort 1: LG-0317 80 mg
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- LinGang Laboratory
RCC, Renal Cell Cancer
A Study Evaluating the Value of 68Ga-NOTA-RCCB6 PET Imaging for Targeting CD70 in the Clinical Staging, Therapeutic Evaluation, and Restaging of Renal Cell Carcinoma, and Comparing It with 68Ga-PSMA PET/CT Imaging
This is a prospective, open-label, single-center clinical study targeting renal cell carcinoma. Sixty patients with a high clinical suspicion of renal cell carcinoma were included.
- Trial name
- NCT06769893
- Testing
- 68Ga-NOTA-RCCB6 PET/CT Scan
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Cavernous Sinus Syndrome, Cavernous Sinus Meningioma
Role of 18F-FDG PET/CT in the Evaluation of Cavernous Sinus Syndrome: a Pilot Study
Cavernous sinus syndrome (CSS) can be caused by a wide range of inflammatory, malignant, benign, vascular and miscellaneous disorders.
- Conditions
- Cavernous Sinus Syndrome, Cavernous Sinus Meningioma, Cavernous Sinus Lesions
- Trial name
- NCT06721130
- Testing
- FDG radiotracer
- Where
- India
- Volunteers
- 54 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Nasopharyngeal Cancer
A Trial of Adjuvant Chemotherapy in Nasopharyngeal Carcinoma Patients With Residual Epstein-Barr Virus (EBV) DNA Following Radiotherapy
The purpose of this trial is to study the benefit of adjuvant chemotherapy using gemcitabine and cisplatin in high risk NPC patients with residual EBV DNA following primary radiotherapy with or without concurrent cisplatin.
- Trial name
- NCT00370890
- Testing
- Adjuvant chemotherapy (gemcitabine and cisplatin)
- Where
- 6 sites in Hong Kong
- Volunteers
- 104 people
- Sponsor
- Chinese University of Hong Kong
NSCLC
18F-FDG PET/CT to Evaluate pD-1 Monoclonal Antibody With First-line Chemotherapy in Advanced NSCLC
This study is a diagnostic study. Subjects were enrolled from clinical stage IIIB or IV NSCLC patients who received standard first-line chemotherapy combined with PD-1 monoclonal antibody immunotherapy and received 18F-FDG PET/CT…
- Trial name
- NCT04996927
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
PET/CT, FAPI
Exploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma
In this prospective study, the investigators will use integrated PET/CT with the agent 68Ga-FAPI and conventional imaging agent 18F-FDG to explore the application value of FAP-targeted molecular imaging in the diagnosis and…
- Conditions
- PET/CT, FAPI, Oral Cancer
- Trial name
- FAPI-OSCC (NCT05030597)
- Testing
- 68Ga-DOTA-FAPI, PET/CT, Participants receive baseline paired FDG and FAPI PET/CT. For resectable locally advanced cases receiving neoadjuvant therapy undergo follow-up FAPI PET imaging.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongnan Hospital
99mTc-FAPI-positive Gastrointestinal Tumor
Comparative Study of 99mTc-FAPI SPECT/CT and 68Ga-FAPI PET/CT
The purpose of this study is to compare the similarities and differences of 99mTc-FAPI quantitative SPECT/CT and 68Ga-FAPI PET/CT in the diagnosis and staging of gastrointestinal tumors, and clinical diagnosis and economic value…
- Trial name
- NCT05444686
- Testing
- 99mTc-FAPI
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Breast Cancer, Breast - Female
Improving Combined PET/CT and MRI of the Breast Using Dedicated Breast Positioning and Image Registration
The goal of this clinical trial is to improve the combined use of PET/CT and MRI for imaging of the breast. PET/CT and MRI are usually performed in different body positions, which can change the shape and position of the breast…
- Trial name
- REPOSE-Breast (NCT07883460)
- Testing
- Prone Breast PET/CT Acquisition
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universität Münster
Cancer
Dynamic Whole-body PET/CT Imaging in Clinical Oncology
The goal of this clinical trial is to to achieve robust quantitative whole- body parametric imaging in clinically feasible scan times in patient with oncologic pathology .
- Trial name
- Dynamic PET/CT (NCT06424873)
- Testing
- PET/CT with FDG or FES
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Valentina Garibotto
Leukemia, Lymphoma
Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT)
The goal of this clinical research study is to learn if adding Zevalin (ibritumomab tiuxetan) to low-intensity chemotherapy (the combination of rituximab, bendamustine, and fludarabine), followed by an allogeneic stem cell…
- Trial name
- NCT01490723
- Testing
- Rituximab, 111In Ibritumomab, Planar Scintigraphy Imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma
68Ga- and 18F-CAIX PET Imaging Study
This exploratory clinical imaging study will evaluate the safety, tolerability, biodistribution, lesion detection, and tumor uptake characteristics of 68Ga- and 18F-labeled carbonic anhydrase IX (CAIX)-targeted positron emission…
- Conditions
- Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma, Renal Tumor
- Trial name
- CAIX-PET (NCT07875946)
- Testing
- 68Ga-CAIX PET/CT, 18F-CAIX
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Cancer
Augmented Whole-body Scanning Via Magnifying PET/CT (AWSM-PET/CT) Techniques Abilities to Improve Upon the Diagnostic Accuracy of the Standard-of-care (SOC) PET/CT for Malignant Lesion Detection
Fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) has been demonstrated to outperform other imaging modalities such as CT and magnetic resonance imaging (MRI) for the detection of metastatic…
- Trial name
- NCT05513027
- Testing
- Augmented Whole-body Scanning via Magnifying PET, PET/CT
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Washington University School of Medicine
Breast Cancer
Comparison Between ER Loss and Triple-Negative Breast Cancer Guided by 18F-FES PET/CT in Metastatic Breast Cancer
This study aimed to compare survival outcomes and clinical characteristics between ER loss and metastatic triple-negative breast cancer (mTNBC) patients, exploring the prognostic implications of dynamic ER changes.
- Trial name
- NCT07316439
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Fudan University
Congenital Hyperinsulinism (CHI), Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)
Phase II Safety and Efficacy Study of 18FDOPA PET-CT in Children With Hyperinsulinemic Hypoglycemia
Children with congenital hyperinsulinism (CHI) have low blood sugar, and some of these children may require surgery to remove part or all of their pancreas.
- Trial name
- 18FDOPA (NCT01468454)
- Testing
- 18 F-DOPA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Children's Hospital of Philadelphia
Cholecystitis
FDG-PET/CT in the Evaluation of Patients With Suspected Cholecystitis
This is a pilot study to investigate the ability of fluorodeoxyglucose-positron emission tomography (FDG-PET) and Positron emission tomography-computed tomography (PET/CT) as a direct method of detecting infection and/or…
- Trial name
- NCT00590395
- Testing
- 18FDG (an FDA-approved radiopharmaceutical)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Alan D. Waxman, M.D.
Neuropathic Pain
A High Frequency Spinal Cord Stimulation PET-CT Scan Study
This study aims to investigate the clinical response to Spinal Cord Stimulation frequency parameters: 40Hz, 4000Hz and 10000Hz and explore the brain imaging changes using PET-CT scans.
- Trial name
- NCT03716557
- Testing
- Spinal Cord Stimulation 4000Hz, Spinal Cord Stimulation 10000Hz, Spinal Cord Stimulation 40Hz
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Barts & The London NHS Trust
Pancreatic Cancer
Preliminary Trial of SNA014 for Pancreatic Cancer
68Ga labeled Claudin 18.2 contrast agent combined with PET/CT for pancreatic cancer
- Trial name
- NCT07597772
- Testing
- 68Ga-NODAGA-SNA006
- Where
- China
- Volunteers
- 12 people
- Sponsor
- SmartNuclide Biopharma
High Grade Serous Ovarian Cancer (HGSOC)
68Ga-FAPI PET/CT in the Staging of High-Grade Epithelial Ovarian Cancers: A Pilot Study
The investigator will use a technology called PET-CT that combines a Positron Emission Tomography (PET) scan with a computed tomography (CT) scan.
- Trial name
- FAST HOC (NCT05956093)
- Testing
- FAPI PET CT
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Brain Cancer
A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression
This study will examine if MRI perfusion and PET/CT can tell growing tumor and radiation injury apart. MRI perfusion looks at the blood vessels in the tumor. PET/CT looks if the tumor cells are actively growing.
- Trial name
- NCT01604512
- Testing
- MRI perfusion and PET/CT scans
- Where
- 6 sites in United States
- Volunteers
- 148 people
- Sponsor
- Memorial Sloan Kettering Cancer Center