Clinical trials: PET-CT
Positron-Emission Tomography, Colorectal Neoplasms
Clinical Study of GPA33-specific PET/CT for the Diagnosis of Colorectal Cancer
In this study, we will first investigate the imaging safety and feasibility of [68Ga]Ga-NOTA-WWH347 and [18F]F-H3RESCA-WWH347 PET/CT in patients with primary and/or metastatic colorectal cancers.
- Trial name
- NCT06203587
- Testing
- [68Ga]Ga-NOTA-WWH347 or [18F]F-H3RESCA-WWH347
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huashan Hospital
Cervical Cancer
FDG-PET and Circulating HPV in Patients With Cervical Cancer
The addition of concurrent chemotherapy to definitive radiation has improved the 5-year survival of women with locally advanced cervical cancer to 58%.
- Trial name
- NCT02388698
- Testing
- Cervical swab, PET-CT, Plasma HPV
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Sunnybrook Health Sciences Centre
Keloid
Analyse of Diagnosis Value of Keloid on 68Ga-RGD PET-CT
Keloids are often described as benign dermal fibroproliferative lesions characterized by increased growth beyond the boundaries of the original wound margin.Fibroblasts are considered to be the key cellular mediators of…
- Trial name
- NCT07660406
- Testing
- 68Ga-RGD
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Breast Neoplasms, Positron Emission Tomography
Comparison of [68Ga]GaFAPI-46 PET/CT and [18F]FDG PET/CT Findings in Breast Carcinoma
The aim of this study is to compare the diagnostic performance of 68Ga-FAPI-46 PET/CT and 18F-FDG PET/CT in primary and metastatic lesions of breast cancer and to reveal the best diagnostic imaging time of 68Ga-FAPI-46 PET/CT.
- Conditions
- Breast Neoplasms, Positron Emission Tomography, Fibroblast Activation Protein Inhibitor, Fluorodeoxyglucose F18
- Trial name
- NCT05339113
- Testing
- 68Ga-FAPI-46 PET/CT
- Where
- Azerbaijan
- Volunteers
- 100 people
- Sponsor
- The National Center of Oncology, Azerbaijan
18F-FAPI PET/CT Examination, Renal Puncture Biopsy
[18F]AlF-NOTA-FAPI-04 PET/CT in Inflammation and Fibrosis in Renal Diseases
The goal of this observational study is to explore the feasibility of using 18F-labeled FAP molecular probe for PET/CT imaging (18F-FAPI PET/CT) to accurately evaluate inflammation and fibrosis in renal diseases.
- Trial name
- NCT05752097
- Testing
- [18F]AlF-NOTA-FAPI-04 PET/CT examination, Renal puncture biopsy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Sichuan Provincial People's Hospital
Systemic Sclerosis (SSc)
As Part of a Pilot Study, Visualization of Inflammatory Activity in Systemic Sclerosis Using CXCR4 PET/CT
Systemic sclerosis (SSc) is a heterogeneous clinical picture consisting of inflammatory, vasculopathic, and fibrotic changes. Initially, inflammatory changes usually occur, which result in fibrosis over time.
- Trial name
- NCT07212959
- Testing
- CXCR4-PET/CT
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Wuerzburg University Hospital
Rectal Cancer, Lymph Node Metastases
FDG - PET / MRI in Patients With Rectal Cancer
The combination of FDG-PET/CT and MRI at staging of rectal cancer in diagnosis is currently very little studied. The investigator have a unique opportunity to study this.
- Trial name
- RECTOPET (NCT03846882)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Region Västerbotten
Neuroendocrine Tumor, Neuroblastoma
18F-MFBG PET/CT in the Evaluation of Neural Crest Tumor
The aim of this study is to evaluate the diagnostic performance and tumor burden of 18F-metafluorobenzylguanidine (18F-MFBG) positron emission tomography (PET) in patients with neuroendocrine tumors mainly in pheochromocytoma and…
- Conditions
- Neuroendocrine Tumor, Neuroblastoma, Pheochromocytoma, Paraganglioma
- Trial name
- NCT05069220
- Testing
- 18F-MFBG, 68Ga-Dotatate
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Thyroid Gland
Diagnostic Value of 18F-Choline PET/CT in Patients With a Thyroid Nodule With an Indeterminate Cytology: Pilot Study
The purpose of the study is to investigate the contribution of PET-CT with F18-choline in the diagnosis of thyroid nodule with indeterminate cytology in order to guide the best indication of surgical resection.
- Trial name
- CHOCOLATE (NCT02784223)
- Testing
- Radiation : PET-CT with F18-choline examination
- Where
- France
- Volunteers
- 107 people
- Sponsor
- Centre Francois Baclesse
Non-Small Cell Lung Carcinoma, Advanced Non-Small Cell Squamous Lung Cancer
Whole Body HER3 Quantification With Radiolabelled Patritumab Deruxtecan (HER3-DXd) PET/CT
Activity of patritumab deruxtecan (U3-1402; HER3-DXd) has been shown in a phase I/II study in patients with HER3 expressing breast cancer as well as in a phase I study in patients with EGFR TKI refractory EGFR mutation positive…
- Conditions
- Non-Small Cell Lung Carcinoma, Advanced Non-Small Cell Squamous Lung Cancer, EGFR Gene Mutation
- Trial name
- NCT06222489
- Testing
- 89Zr-Patritumab deruxtecan
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- The Netherlands Cancer Institute
MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography
PET-CT Imaging Features of Meibomian Glands
Analysis the results of Dry eye analysis results and PET-CT imaging comprehensively
- Conditions
- MGD-Meibomian Gland Dysfunction, Positron-Emission Tomography, Dry Eye
- Trial name
- NCT06324890
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Migraine in Adults
The Effect of Static Magnetic Fields on Neuroinflammation in Migraine
We are conducting this research in individuals with migraines to find out if a daily magnet helmet application could alter migraine-related brain inflammation.
- Trial name
- NCT07584382
- Testing
- Static magnetic helmet
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Marco Loggia
Psoriasis, Cardiovascular Disease
Vascular Inflammation in Psoriasis Trial (The VIP Trial)
The purpose of this study is to assess the effect of adalimumab (Humira), when compared to NB-UVB (narrow-band ultraviolet B) phototherapy or placebo (an inactive substance that may resemble an active substance but has no medical…
- Trial name
- VIP (NCT01553058)
- Testing
- Adalimumab (Humira), NB-UVB phototherapy
- Where
- 9 sites in United States
- Volunteers
- 97 people
- Sponsor
- University of Pennsylvania
Cigarette Smoker, Current Smoker
18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules
This phase II trial studies how well 18F-FSPG positron emission tomography (PET)/computed tomography (CT) work in diagnosing early lung cancer in patients with indeterminate lung nodules.
- Conditions
- Cigarette Smoker, Current Smoker, Former Smoker, Multiple Pulmonary Nodules
- Trial name
- NCT03824535
- Testing
- Computed Tomography, Fludeoxyglucose F-18, Fluorine F 18 L-glutamate Derivative BAY94-9392
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrei Iagaru
Non-Small Cell Lung Cancer NSCLC
Clinical Study of 18F-Alfatide Injection PET/CT
This is a multicenter, open, non-inferiority Phase III clinical study to evaluate the efficacy of 18F-Alfatide Injection PET/CT compared with 18F-FDG PET/CT in the diagnosis of lymph node metastasis in non-small cell lung cancer.
- Trial name
- NCT06416852
- Testing
- 18F-Alfatide Injection, 18F-FDG Injection
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Yantai LNC Biotechnology Singapore PTE. LTD.
Prostate Cancer
PSMA-PET/CT Registry
This is a prospective registry study to evaluate the diagnostic utility of [18F]-PSMA-1007 (PSMA-PET/CT) to stage patients with high-risk prostate cancer, localize sites of biochemical recurrence of prostate cancer, and restage…
- Trial name
- NCT05709535
- Testing
- [18F]-PSMA-1007
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- AHS Cancer Control Alberta
Giant Cell Arteritis, Vasculitis
FDG Digital PET/CT as First Line Investigation for Giant Cell Arteritis
Giant cell arteritis (GCA) causes inflammation of the arteries and can lead to serious complications such as blindness, necessitating rapid diagnosis and treatment.
- Trial name
- NCT05000138
- Testing
- FDG PET/CT
- Where
- 5 sites in Canada, France and 1 more
- Volunteers
- 92 people
- Sponsor
- Jewish General Hospital
Adult Medulloblastoma, Childhood Medulloblastoma
Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CT
This clinical trial studies gallium Ga 68-edotreotide positron emission tomography (PET)/computed tomography (CT) compared with indium In 111 pentetreotide plus contrast-enhanced CT (or MRI) in diagnosing patients with…
- Conditions
- Adult Medulloblastoma, Childhood Medulloblastoma, Neuroblastoma, Neuroendocrine Tumor
- Trial name
- NCT01869725
- Testing
- gallium Ga 68-edotreotide, positron emission tomography/computed tomography, indium In 111 pentetreotide
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Sue O'Dorisio
Advanced Nasopharyngeal Carcinoma
New Approach of Assessing Drug Response for Treatment of Nasopharyngeal Cancer
The combination of pEBV DNA (half-life) and PET-CT following 1 course of chemotherapy allow earlier and more detection of drug response in advanced NPC than RECIST method, in patients with previously untreated advanced NPC who…
- Trial name
- NCT01365208
- Testing
- Chemotherapy
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Mild Traumatic Brain Injury
Advanced Imaging Tools in the Study of Mild Traumatic Brain Injury
We will utilize a set of imaging modalities including computed tomography (CT), positron emission tomography (PET), and a suite of magnetic resonance imaging (MRI) tools, to investigate the changes in the human brain resulting…
- Trial name
- mTBI (NCT01044615)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kettering Health Network
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