Clinical trials: PET-CT
Cardiac Amyloidosis
Molecular Imaging of the Underlying Mechanism of Cardiotoxicity in Patients With Light Chain Amyloidosis Using PET/CT
The research study is being conducted to test how two different types of Positron Emission Tomography (PET/CT) scans could be used to image a type of heart disorder called amyloidosis (AL). There will be two groups in the study.
- Trial name
- NCT04105634
- Testing
- FNOS, Florbetaben
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Pennsylvania
Oropharynx Cancer
Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer
This prospective study aims to utilize pre- and mid-treatment PET-CT to guide de-escalation of radiation therapy in HPV-related squamous cell carcinoma of the oropharynx.
- Trial name
- NCT03416153
- Testing
- Carboplatin, Radiation Therapy, Paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- University of Michigan Rogel Cancer Center
Lung Adenocarcinoma, 18F-FDG
18F-FDG and 68Ga-FAPI PET/CT in Lung Adenocarcinoma
To evaluate the potential usefulness of 68Ga-FAPI positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in lung adenocarcinoma, compared with 18F-FDG PET/CT.
- Conditions
- Lung Adenocarcinoma, 18F-FDG, 68Ga-FAPI, PET/CT
- Trial name
- NCT04588064
- Testing
- 68Ga-FAPI PET/CT scan
- Where
- China
- Volunteers
- 63 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Inflammatory Disease
68Gallium-FAPI46 PET/CT Imaging in Chronic Inflammatory and Fibrotic Diseases
This single-center pilot study is designed to explore the preliminary utility of the [68Ga] Ga-FAPI imaging agent in positron emission tomography (PET) combined with computed tomography (CT) for a range of chronic inflammatory…
- Trial name
- PARADISE (NCT06275477)
- Testing
- 68Ga-FAPI46
- Where
- France
- Volunteers
- 390 people
- Sponsor
- University Hospital, Brest
Prostate Cancer
Comparing PET-CT Using C-11 Choline and 18F-Fluoromethylcholine in Patients With Metastatic Prostate Cancer
RATIONALE: Diagnostic procedures, such as positron emission tomography (PET) and computed tomography (CT) imaging, may help find and diagnose metastatic prostate cancer.
- Trial name
- NCT01132599
- Testing
- C-11 choline, 18F-fluoromethylcholine
- Where
- United Kingdom
- Sponsor
- Cancer Research UK
Type 2 Diabetes, Healhty
Insulin-Mediated Glucose Uptake and Organ Perfusion Assessed by Total-Body PET During GIP and GLP-1 Infusion
This study investigates how the naturally occurring gut hormones GIP and GLP-1 influence whole-body glucose uptake and organ perfusion in humans.
- Trial name
- NCT07398300
- Testing
- GIP, GLP-1, Saline (0.9% Sodium Chloride)
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostate Cancers, Breast Cancer
To Assess the Correlation of High-resolution Specimen PET-CT Imaging, Using the XEOS AURA 10 PET-CT, With the Histopathology Results and Long-term Outcome of Patients Undergoing Resective Cancer Surgery.
This registry study aims to evaluate the effectiveness and clinical impact of specimen PET-CT imaging by analyzing the correlation between specimen PET-CT images, intraoperative interpretations, and histopathological findings.
- Conditions
- Prostate Cancers, Breast Cancer, Head and Neck Cancer, Cancer
- Trial name
- PETRiS (NCT06970275)
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 850 people
- Sponsor
- XEOS Medical
Neoplasms, Antioxidants
Oxidoreductive Balance and Lysosomal Activity in Cancer Patients.
The research aims to determine the parameters of oxidative stress and inflammatory processes and compare these parameters with the image obtained using positron emission tomography (PET) with 2-deoxy-2-[fluorine-18]fluoro…
- Conditions
- Neoplasms, Antioxidants, Oxidative Stress, Lipid Peroxidation
- Trial name
- NCT03470857
- Testing
- Patients
- Where
- 3 sites in Poland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University
Bone Metastases
F18PET/CT Versus TC-MDP Scanning to Detect Bone Mets
The primary objective is to compare the diagnostic performance of 18F- Fluoride PET/CT scanning to that of conventional bone scanning for detecting cancer that has spread to the bone (bone metastasis).
- Trial name
- NCT00882609
- Testing
- Bone Scan: F18-Fluoride PET/CT or TC-MDP
- Where
- 19 sites in United States, Australia and 3 more
- Volunteers
- 550 people
- Sponsor
- American College of Radiology - Image Metrix
Prostatic Neoplasm
Determination of the Diagnostic Detection Rate of Axumin (Fluciclovine) Digital PET/CT, Post-prostatectomy
Fluciclovine F18 (Axumin) has been demonstrated to provide good delineation of recurrence of prostate cancer after definitive therapies.
- Trial name
- NCT04234399
- Testing
- Fluciclovine PET/CT using a digital PET/CT
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Vermont
Malignant Neoplasm
18F-Clofarabine PET/CT in Imaging Cancer Patients Before and After Interventions
This clinical trial studies 18F-clofarabine positron emission tomography (PET)/computed tomography (CT) in imaging patients with cancer before and after treatment with a therapy that activates the patient's immune system…
- Trial name
- NCT02888301
- Testing
- Computed Tomography, Fluorine F 18 Clofarabine, Positron Emission Tomography
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Stage III Ovarian Cancer, Stage IV Ovarian Cancer
18F-DCFPyL PET/CT in High-grade Epithelial Ovarian Cancer (PET HOC)
The purpose of this study is to determine whether high grade epithelial ovarian cancers (=HG EOC) are 18F-DCFPyL (=2-(3-(1-carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl)-ureido)-pentanedioic acid)-avid and to…
- Trial name
- NCT03811899
- Testing
- 18F-DCFPyL
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Tumor, Cardiovascular Diseases
Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases
The purpose of this study is to conduct clinical research on [68Ga] Ga-NI-FAPI-04 PET/CT imaging and further investigate its diagnostic value in fibroblast activation related diseases.
- Conditions
- Tumor, Cardiovascular Diseases, Pulmonary Fibrosis, Rheumatic Immune Diseases Involving Large Blood Vessels
- Trial name
- NCT07464132
- Testing
- Injection of 68Ga-NI-FAPI
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
WHO Grade 3 Glioma, WHO Grade 4 Glioma
An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma
This clinical trial evaluates whether gallium-68 (Ga-68) prostate specific membrane antigen (PSMA)-11 positron emission tomography (PET)/computed tomography (CT) imaging is useful in differentiating between disease that has come…
- Trial name
- NCT06444412
- Testing
- Computed Tomography, Electronic Health Record Review, Ga 68 PSMA-11
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Malignant Neoplasm
18F-FAPIBiotin PET/CT: Dosimetry and Biodistribution Study
As a new dual targeting PET radiotracer, 18F-FAPI-Biotin is promising as an excellent imaging agent applicable to various cancers.
- Trial name
- NCT06734572
- Testing
- 18F-FAPIBiotin
- Where
- China
- Volunteers
- 5 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Squamous Cell Carcinoma of the Oral, Clinically Node-Negative and Radiology
Predictive Value of PET CT in the Histologic Lymph Node Status of Patients With Squamous Cell Carcinoma of the Oral N0 Clinical and Radiological Cavity.
Squamous cell carcinoma of the VADS represents the majority of cancers in ENT. Metastatic lymph node involvement is an important prognostic factor.
- Trial name
- ORNICA (NCT03947892)
- Testing
- PET-CT
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Non-small Cell Lung Cancer
Macrophage Imaging Using Ga-MMR-VHH2 in Lung Cancer Patients
Phase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with non-small…
- Trial name
- MAGMA (NCT05933239)
- Testing
- 68GaNOTA-Anti-MMR-VHH2
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitair Ziekenhuis Brussel
CKD, Renal Fibrosis
FAP-targeting PET/CT for Noninvasive Monitoring of Renal Fibrosis
Chronic kidney disease (CKD) is an irreversible change of kidney function and structure caused by many reasons. The main threat of CKD to human health is progressive renal function decline.
- Trial name
- NCT06563765
- Testing
- FAP-targeting PET/CT imaging will be performed on the enrolled patients.
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University First Hospital
Ventricular Tachycardia
Study of Cardiac PET/CT Imaging to Guide Ablation Treatment of Ventricular Tachycardia
Imaging is to be performed prior to procedure using positron emission tomography/ computed tomography (PET/CT), after a special dye is injected.
- Trial name
- NCT02962076
- Testing
- [C-11] Meta-hydroxyephedrine radioactive tracer (MHED)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Khaled Awad, MD
Microglial Cells Activation Imaging
Microglial Cells Activation Imaging Using PET-CT With 18F-DPA714
There is accumulating evidence suggesting that inflammatory processes, through microglial activation, would play a key role in brain injury and degeneration.
- Trial name
- NCT04171882
- Where
- 2 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Weibing Miao, PhD
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