Clinical trials: PET-CT
Neuroendocrine Tumors
61Cu-NODAGA-LM3 PET/CT for the Detection of Neuroendocrine Tumors (COPPER PET in NET)
The goal of this monocentric, open-label, randomized-controlled, reader-blind clinical study is to assess the safety of the radiolabeled somatostatin receptor ligand, 61Cu-NODAGA-LM3, and its sensitivity in comparison to the…
- Trial name
- NCT06455358
- Testing
- 61Cu-NODAGA-LM3, Comparator
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- University Hospital, Basel, Switzerland
Esophageal Cancer
Dose Escalation by Boosting Radiation Dose Within the Primary Tumor Using 18FDG-PET/CT for Unresectable Thoracic Esophageal Cancer
Most local failures after definitive chemoradiation for unresectable esophageal cancer occur in the gross tumor volume (GTV). And the metabolic active areas post-treatment were located in the high FDG uptake areas prior to the…
- Trial name
- NCT01843049
- Testing
- Radiotherapy, Chemotherapy (5-FU+DDP)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fudan University
Breast Cancer
Characterizing Breast Cancer With 68Ga-FAPI PET/CT (PFB-01)
Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts (CAFs), which constitute a major proportion of cells within the tumor microenvironment, especially in breast cancer.
- Trial name
- NCT05574907
- Testing
- 68Ga-FAPI PET/CT scan
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Dual Integrin αvβ3 and GRPR Targeting PET Imaging in Breast Cancer Patients
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-BBN-RGD in breast cancer patients.
- Trial name
- NCT02749019
- Testing
- 68Ga-NOTA-BBN-RGD
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Testis Cancer, Germ Cell Tumor
Role of Axumin PET Scan in Germ Cell Tumor
Investigators will use Axumin PET/CT to help with the imaging modalities to determine the presence of occult retroperitoneal disease.
- Conditions
- Testis Cancer, Germ Cell Tumor, Testicular Cancer, Germ Cell Tumor of Testis
- Trial name
- TESTPET (NCT03426865)
- Testing
- Axumin PET scan
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Texas Southwestern Medical Center
Carcinoma, Non-Small-Cell Lung, Thymus Neoplasms
18F FLT Imaging Studies of Treatment Response for Lung Cancer and Thymoma
Background: Imaging studies like positron emission tomography (PET) and computed tomography (CT) scans are used to detect tumor responses to cancer treatment.
- Trial name
- NCT01610544
- Testing
- 3'-deoxy-3'-18F fluorothymidine (FLT), PET/CT scan
- Sponsor
- National Cancer Institute (NCI)
Diabetes Mellitus, Type 2, Vascular Inflammation
The Effect of Statin Treatment on Arterial Wall Inflammation as Assessed With 68Ga-DOTATATE PET-CT
To study the effect of atorvastatin treatment on vascular uptake of 68Ga-DOTATATE in patients with Type 2 Diabetes.
- Trial name
- CARAMEL (NCT05730634)
- Testing
- Atorvastatin 40 Mg Oral Tablet
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Crohn Disease
Use of FDG PET/CT to Evaluate Crohn Disease
The purpose of this study will permit to determine the role of FDG PET/CT to diagnose Crohn Disease and recurrence of Crohn disease after having compared results of PET/CT's with results of exams routinely performed(colonoscopy…
- Trial name
- NCT00383344
- Testing
- FDG PET/CT
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Eric Turcotte
Prostate Cancer, Prostate Cancer Recurrent
Efficacy of [18F]PSMA-1007 PET/CT in Patients With Biochemial Recurrent Prostate Cancer
This study evaluates the diagnostic performance and safety of [18F]PSMA-1007 PET/CT imaging in patients with suspected recurrence of prostate cancer after previous definitive treatment.
- Trial name
- NCT04742361
- Testing
- [18F]PSMA-1007
- Where
- 6 sites in United States, Netherlands and 1 more
- Volunteers
- 136 people
- Sponsor
- ABX advanced biochemical compounds GmbH
Prostate Cancer Diagnosis
PSMA PET Scan and mpMRI for Prostate Cancer Detection
Prospective, randomized, phase 2 clinical trial to determine if PSMA PET imaging plus mpMRI improves detection of clinically significant prostate cancer as compared to mpMRI alone.
- Trial name
- NCT05820724
- Testing
- PSMA PET scan, No PSMA PET, 18F- DCFPyl Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Non-small-cell Lung Cancer
18F-FDG Metabolism Imaging Monitoring Non-small Cell Lung Cancer Curative Effect of Chemotherapy Multicenter Clinical Study
The subject is going to use 18F-FDG PET/CT to assess different genetic NSCLC metabolism after cisplatin chemotherapy and targeted therapy, define the assessment criteria for the role of 18F-FDG PET/CT in NSCLC treatment respone…
- Trial name
- NCT02938546
- Testing
- 18F-FDG
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Neuroendocrine Tumors
Evaluation of the Diagnostic and Prognostic Role of PET (PET/CT and PET/MRI) in Neuroendocrin Tumors.
Neuroendocrine tumors (NETs) constitute approximately 0.5% of malignancies. To date, diagnosis at an increasingly early stage of the disease is possible thanks to recent technological advances in biomedical imaging.
- Trial name
- NCT06159920
- Testing
- diagnostic accuracy
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS San Raffaele
Tumor
68Ga-DOTA-NI-FAPI04 PET/CT in Patients With Various Types of Cancer
As a novel radiotracer targeting fibroblast activation protein (FAP), 68Ga-DOTA-NI-FAPI04 is a novel agent incorporating a hypoxia sensitive nitroimidazole(NI)-moiety and a FAP-targeting.
- Trial name
- NCT06455761
- Testing
- 68Ga-DOTA-NI-FAPI04, 68Ga-FAPI/18F-FDG
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Prostate Cancer
Interest of Trimodality PET-CT Choline MRI Before Radiotherapy in High Risk Prostate Cancer
The initial staging of locally advanced prostate cancer is made with Computed Tomography scan (CT), Magnetic Resonance Imaging (MRI), and bone scan (BS).
- Trial name
- DEMETER (NCT03734757)
- Testing
- imaging in trimodality
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Henri Becquerel
HER2-negative Breast Cancer, ER Positive Breast Cancer
D4 Choline Breast PET/CT
The aim of this study is to evaluate the effect of CDK4/6 inhibitor treatment on the tumour choline metabolism as determined by [18F]D4-FCH PET/ computed tomography(CT) in breast cancer and to determine the suitability of…
- Conditions
- HER2-negative Breast Cancer, ER Positive Breast Cancer, Metastatic Breast Cancer
- Trial name
- NCT04276272
- Testing
- Imaging scan
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Imperial College London
Cardiac Sarcoidosis
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression
This is a pilot mechanistic study of the diagnostic utility of sodium-glucose cotransporter-1/2 inhibition (SGLT1/2) on myocardial glucose suppression on FDG PET/CT.
- Trial name
- NCT06510894
- Testing
- Sotagliflozin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Diabetes Mellitus Type 2
Adipose Tissue Imaging in Type 2 Diabetes
The metabolic function of different white adipose tissue depots in the body and its role in the development of type 2 diabetes (T2D) remains unclear.
- Trial name
- ATI-DM2 (NCT02528695)
- Testing
- 18F-FDG PET/CT, euglycemic clamp, hypoglycemic clamp
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Coronary Artery Disease, Coronary Artery Calcification
Coronary Artery Calcification Assessed on PET Scanner (PET : Positron Emission Tomography)
Calcification artery calcium (CAC) scoring is a valuable tool for determining the risk of major adverse cardiac events. It was found that CAC can be quantitatively assessed, by manual scoring or using deep-learning, on low-dose…
- Trial name
- CALCOTEP (NCT06379295)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Sarcoma
PET Scan Combined With CT Scan in Evaluating Treatment Response in Patients Undergoing Treatment for Bone Cancer or Soft Tissue Sarcoma
RATIONALE: Diagnostic procedures, such as PET scan and CT scan, may help doctors determine the extent of cancer and predict a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00335751
- Testing
- positron emission tomography computed tomography (PET/CT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer
Molecular Imaging of Breast Cancer With Breast PET/CT
This study is a feasibility study to determine if a combined breast PET/CT scanner can image malignant functional activity while determining anatomical structure in the same clinical setting for patients with breast cancer.
- Trial name
- NCT00584753
- Testing
- Positron emission tomography and computed tomography
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
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