Clinical trials: PET-CT
Tinnitus
Using PET-CT to Target and Validate Low-frequency TMS as Treatment for Tinnitus
One out of every five people experience tinnitus (a buzzing, ringing, or roaring sound in the ear) ranging from mild to severe impairment. To date there is no effective therapy that seems to help the tinnitus sufferer.
- Trial name
- NCT00329524
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Adult Anaplastic Ependymoma, Adult Anaplastic Oligodendroglioma
18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas
To evaluate 18F-FDOPA PET obtained from PET/CT or PET/MRI imaging in patients with newly diagnosed or recurrent gliomas.
- Conditions
- Adult Anaplastic Ependymoma, Adult Anaplastic Oligodendroglioma, Adult Brain Stem Glioma, Adult Diffuse Astrocytoma
- Trial name
- NCT02175745
- Testing
- 18F-fluoro-dihydroxyphenylalanine, Positron emission tomography (PET), Computed tomography (CT)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Erik Mittra
Esophageal Squamous Cell Carcinoma, Positron Emission Tomography
Quantitative Evaluation of Metastatic Lymph Nodes With Dynamic 18F-FDG PET/CT in Patients With ESCC
Currently, static scans are commonly used for Positron Emission Tomography/Computed Tomography (PET/CT) examination in the literature.
- Trial name
- NCT04514822
- Testing
- Dynamic PET
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Giant Cell Arteritis
Use of Gallium-68 HA-DOTATATE PET/CT in Giant Cell Arteritis (GCA)
The aim of this study is to compare the use of FDG PET/CT to Ga-68 HA-DOTATATE (abbreviated DOTATATE) PET/CT in patients with active giant cell arteritis (GCA) started on prednisone to understand if DOTATATE can identify more…
- Trial name
- NCT03812302
- Testing
- 68-Ga HA-DOTATATE PET/CT
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Alberta
To Evaluate the Effect of Pioglitazone on Glucose Metabolism of Fat Tissue by Using FDG-PET/CT Imaging
Pioglitazone Decreases Visceral Fat Metabolism
Excess visceral fat is associated with chronic systemic inflammation and cardiovascular complications. Pioglitazone has been reported to variably influence visceral fat volume, but it its effect on metabolic activity of the…
- Trial name
- NCT01819402
- Testing
- Pioglitazone vs Glimepiride
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kurume University
Metastatic Triple-Negative Breast Carcinoma
Molecular PD-L1 PET/CT Imaging With 89Zr-atezolizumab in Metastatic Triple Negative Breast Cancer
The overarching purpose of this study is to improve precision medicine through more refined therapy selection for breast cancer patients who are candidates for ICI therapy (monoclonal antibodies targeting the programmed death…
- Trial name
- MIMIR-mTNBC (NCT05742269)
- Testing
- 89Zr-atezolizumab PET/CT
- Where
- Sweden
- Volunteers
- 3 people
- Sponsor
- Karolinska University Hospital
T-NK Cell Lymphoma
The Value of PET Imaging Targeting Granzyme B in Predicting Efficacy and Prognosis in T-NK Cell Lymphoma
The study on the value of PET imaging targeting granzyme B in predicting the efficacy and prognosis of T-NK cell lymphoma.
- Trial name
- NCT06863441
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruijin Hospital
Renal Excretion, Bacterial Infections
Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic Acid
The investigators will perform radionuclide PET scans in subjects with infectious diseases to assess whether radio-labeled PABA (11C-PABA) is effective for infection imaging.
- Conditions
- Renal Excretion, Bacterial Infections, Inflammatory Disease, Oncologic Disease
- Trial name
- NCT05611905
- Testing
- 11C-para-aminobenzoic acid PET/CT, Probenecid
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Johns Hopkins University
Brain Tumor
FBY PET/CT in Patients With Brain Tumors
This study is an open-labeled phase II diagnostic clinical trial to explore the safety and clinical value of FBY in suspected adult brain tumor patients.
- Trial name
- NCT03980431
- Testing
- FBY PET Examination
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Lung Cancer
Improving Clinical PET/CT Image Quality in Retrospectively Reconstructed Breath-Hold Images
The patient has been referred for an FDG PET/CT scan. FDG is a form of sugar that contains a small amount of radioactivity; it is used to see the size and possible spread of cancer in the body.
- Trial name
- NCT01109953
- Testing
- Breath-Hold PET/CT image set
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Ovarian Neoplasms, Ovarian Cancer
18F-CP18 Imaging Studies for Cancer Treatment With Birinapant
Background: 18F-CP18 is a chemical designed for use in imaging studies. It is attracted to tumor cells that are being killed by cancer treatment.
- Conditions
- Ovarian Neoplasms, Ovarian Cancer, Fallopian Tube Neoplasms, Fallopian Tube Cancer
- Trial name
- NCT01766622
- Testing
- [18F]-CP18, PET/ CT
- Sponsor
- National Institutes of Health Clinical Center (CC)
Rectal Cancer
A Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer
The combination of short course radiotherapy and immunotherapy helps to increase the proportion of pathological complete response after neoadjuvant therapy, providing more patients with the opportunity for organ preservation.
- Trial name
- NCT06608537
- Testing
- neoadjuvant SCRT followed by Sintilimab plus CAPOX
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Sun Yat-sen University
Breast Cancer Invasive
Diagnostic Performance of [18F]FES PET/CT for Axillary LN Metastasis in ER-positive Breast Cancer
This study aims to explore the diagnostic performance of [18F]FES PET/CT for the evaluation of axillary lymph node metastasis in patients with ER-positive breast cancer having clinically suspected or confirmed axillary lymph node…
- Trial name
- NCT06695039
- Testing
- Fluoroestradiol (18F)
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- Asan Medical Center
Malignant Melanoma
Comparison of PET/CT and Ultrasound in Staging of Malignant Melanoma
This is the first study which evaluates the different staging modalities 18F-2-fluoro-2-deoxy-D-glucose PET/CT (PET/CT) and diagnostic ultrasound (US) in a single patient cohort with malignant melanoma (MM).
- Trial name
- NCT04253574
- Testing
- Imaging with 18F-FDG PET/CT and/or Ultrasound
- Volunteers
- 258 people
- Sponsor
- University of Basel
Metastatic Neuroblastoma
A Phase I/II Study of [124I]mIBG PET/CT in Neuroblastoma
This study aims to show that 3-dimensional PET/CT imaging with a new novel PET tracer (called [124I]mIBG) can detect as many or more sites of neuroblastoma (a type of childhood cancer) compared to the recommended 1-dimensional…
- Trial name
- NCT02043899
- Testing
- [124I]meta-Iodobenzylguanidine
- Where
- 2 sites in United Kingdom
- Volunteers
- 36 people
- Sponsor
- Cancer Research UK
Lymphoma, Extranodal NK-T-Cell
Evaluating 18F-FDG PET/CT With Liver SUVmax-based Criteria for Prognosis of Patients With Natural Killer/T-cell Lymphoma
The purpose of this study is to evaluate whether a semi-quantitative interpretation using the liver SUVmax as reference can better interpret 18F- FDG PET/CT and predict disease progression during chemotherapy or survival in…
- Trial name
- NCT03051542
- Testing
- 18F-FDG PET/CT
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Cancer Hospital & Institute
Lymphoma, T-Cell, Peripheral
18F-FDG PET/CT-based Prognostic Model for Predicting Outcome in Patients With Peripheral T-cell Lymphoma
The purpose of this study is to evaluate whether 18F-FDG PET/CT-based prognostic model of PTCL can predict disease progression
- Trial name
- NCT03051581
- Testing
- 18F-FDG PET/ CT
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Cancer Hospital & Institute
Lymphoma
Diffusion-weighted Magnetic Resonance Imaging in Post Therapy Patients With Lymphoma
The goal of this study is to determine the feasibility of the diffusion weighted Magnetic Resonance Imaging in the evaluation of the treatment response in patients with malignant lymphoma.
- Trial name
- NCT03969381
- Testing
- diffusion weighted magnetic resonance image in lymphoma
- Volunteers
- 50 people
- Sponsor
- Assiut University
PET Images and Deep Neural Networks Algorithms
Positron Emission Tomography (PET) Images Using Deep Neural Networks
PET images are based on detecting two annihilation 511 KeV photons that are produced by positron emitting isotopes. The longer the acquisition time, the more photons are detected and processed, resulting in better image quality.
- Trial name
- NCT04140565
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Obesity
Investigating Glucose Metabolism of LEAP2 With Total-body PET/CT
The naturally occurring hormone LEAP2 is proposed to have opposite effects to that of the 'hunger hormone' ghrelin. Other that appetite regulation, LEAP2 is involved in glucose metabolism through mechanisms yet not fully…
- Trial name
- LEAP2-PET/CT (NCT06254365)
- Testing
- Exogenous LEAP2 hormone
- Where
- Denmark
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
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