Clinical trials: PET-CT
Histologically-confirmed Malignancies
Serial FLT PET Imaging in Cancer Patients for Monitoring of Response to Therapy
The purpose of this study is to see if PET/CT scans that use a radioactive substance called [18F] fluorothymidine (FLT), can detect and monitor changes in the tumor.
- Trial name
- NCT02139150
- Testing
- [18F] FLT, PET/CT scans
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Localized Prostate Cancer
Functional Image-Guided Carbon Ion Irradiation With Simultaneous Integrated Boost for Prostate Cancer
This is a phase II randomized controlled clinical trial to assess the toxicities and clinical efficacy of prostate specific membrane antigen (PSMA) positron emission tomography / computed tomography (PET/CT) and multi- parameter…
- Trial name
- NCT05010343
- Testing
- carbon ion irradation, Carbon Ion Irradiation With SIB
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shanghai Proton and Heavy Ion Center
Siewert Type I-II Adenocarcinoma of the Esophagus
Siewert Type I-II: CT, PET-CT, EUS Sensitivity/Specificity for the Assessment of Lymph Node Metastases
In Siewert type I/II EAC, sensitivity/specificity of CT, PET-CT, EUS for assessment of N descriptor in defined groups of lymph nodes were investigated.
- Trial name
- ADECC2-2017 (NCT03529968)
- Testing
- esophagectomy
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- University of Bologna
18F-FDG, Neuroblastoma
Diagnostic Efficacy and Prognostic Value of 18F-FDG PET/CT (MR) in Pediatric Solid Blastoma
the primary histologic origin of extracranial solid tumors in children is malignant embryonic cells, including Neuroblastoma (NB) , Hepatoblastoma(HB), and kidney, wilms' tumor(WT).
- Conditions
- 18F-FDG, Neuroblastoma, Hepatoblastoma, Wilms Tumor
- Trial name
- NCT06190574
- Testing
- Telephone follow-up
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pheochromocytoma/Paraganglioma (PPGL)
Al18F-NOTA-LM3 PET/CT in Patients With Pheochromocytoma and Paraganglioma
The aim of this study is to evaluate the diagnostic performance of Al18F-NOTA-LM3 PET/CT and compare it with 68Ga-DOTATATE PET/CT in patients with pheochromocytoma/paraganglioma (PPGL).
- Trial name
- NCT07288931
- Testing
- Diagnostic Test: Al18F-NOTA-LM3, Diagnostic Test: 68Ga-DOTATATE
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Non-small Cell Lung Cancer
Utility of Routine Cervical Mediastinoscopy in Clinical Stage I Non-Small Cell Lung Cancer (NSCLC)
To prospectively look at the utility of routine cervical mediastinoscopy (lymph node biopsy) in patients with clinically staged T2N0M0 NSCLC, as well as patients with clinically staged T1N0M0 NSCLC with a high maxSUV of the…
- Trial name
- NCT01146366
- Where
- 4 sites in United States
- Volunteers
- 111 people
- Sponsor
- Jennifer Bell
Neuroendocrine Tumors
Using 18F- FDG,18F-DOPA and 68Ga-DOTATATE PET/CT in Detection and Evaluation of Response in Patients With NET Undergoing PRRT
the investigators will follow up after patients with neuroendocrine tumors who undergo PRRT treatment and evaluate the response for treatment using PET/CT with different tracers
- Trial name
- NCT04622631
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Dr. Nayruz Knaana
Prostate Cancer Patients
C-Acetate PET/CT Imaging to Evaluate Treatment Changes in Prostate Cancer
Patients with castrate resistant prostate cancer (CRPCA) with osseous metastatic disease planning to undergo Ra-223 therapy may be eligible for this study.
- Trial name
- NCT02715583
- Testing
- 11C-Acetate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Prostate Cancer
Safety and Preliminary Diagnostic Performance of [⁶⁴Cu]Cu-RAX301 in Prostate Cancer
This is a prospective, open-label, multicenter, Phase I/II exploratory diagnostic imaging study to evaluate the safety, tolerability, radiation dosimetry, pharmacokinetics, biodistribution, imaging characteristics, and…
- Trial name
- COPRA424 (NCT07765940)
- Testing
- [⁶⁴Cu]Cu-RAX301 Injection
- Volunteers
- 52 people
- Sponsor
- RadAlliance Therapeutics, Inc
Advanced Nasopharyngeal Carcinoma
New Approach of Assessing Drug Response for Treatment of Nasopharyngeal Cancer
The combination of pEBV DNA (half-life) and PET-CT following 1 course of chemotherapy allow earlier and more detection of drug response in advanced NPC than RECIST method, in patients with previously untreated advanced NPC who…
- Trial name
- NCT01365208
- Testing
- Chemotherapy
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- Chinese University of Hong Kong
Primary Hyperparathyroidism, Parathyroid Cancer
Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors
Background: People have 4 parathyroid glands near the thyroid gland in the neck. Surgery is needed to remove a parathyroid gland that is too large or has a tumor.
- Conditions
- Primary Hyperparathyroidism, Parathyroid Cancer, Multiple Endocrine Neoplasias, Heritable Hyperparathyroidism
- Trial name
- NCT07444723
- Testing
- 18F-FCH, NeuroEXPLORER
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
PET/CT
Assessing Ultra-low Dose PET/CT and CT-less PET Using a Long Axial Field-of-view PET/CT System
Latest generation extended axial field-of-view (FOV) PET/CT systems offer the potential for substantial reductions in applied radiopharmaceutical necessary for a clinical scan.
- Trial name
- ULD-PET (NCT05496920)
- Testing
- FD-PET/CT, LD-PET/CT
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lung Diseases, Interstitial, Pneumonitis, Interstitial
Rituximab in Interstitial Pneumonitis
This project will address rare immune mediated inflammatory diseases (IMIDs) involving the lungs, i.e. interstitial pneumonitis (IP).
- Trial name
- RITUX-IP (NCT02251964)
- Testing
- Rituximab, Zr-89-rituximab immuno PET/CT
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Human Adams
Breast Tumor
68Ga-NOTA-RM26 PET/CT in Breast Tumor Patients
This is an open-label positron emission tomography/computed tomography(PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-RM26 in breast tumor patients.
- Trial name
- NCT03347864
- Testing
- 68Ga-NOTA-RM26
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Endometriosis
Use of a New Diagnostic Tool in the Detection and Characterization of Endometriosis Lesions
Diagnostic wandering is one of the characteristics of endometriosis due to great anatomical and clinical variability but also due to poorly relevant diagnostic examinations.
- Trial name
- ENDO-TEP (NCT07053982)
- Testing
- Preoperative [18F]-FES PET/CT Imaging and Estrogen Receptor Expression Analysis in Endometriosis Surgery
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Transthyretin Amyloid Cardiomyopathy
A Research Study to Look at the Distribution and Effects of Coramitug on Amyloid Deposits in Heart Tissue Using PET/CT Imaging in People With ATTR Amyloidosis.
The study is conducted in participants with Transthyretin Amyloid Cardiomyopathy (ATTR-CM), a heart disease that occurs in people with the disease ATTR amyloidosis.
- Trial name
- NCT07448623
- Testing
- Coramitug
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Novo Nordisk A/S
Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Squamous Cell Carcinoma in Cervical Lymph Node
Fluciclovine F18 PET/CT in Identifying the Origin of Head and Neck Squamous Cell Carcinoma in Patients With Metastatic Cervical Nodal Disease
This early phase I trial studies how well fluciclovine F18 positron emission tomography (PET)/computed tomography (CT) works in identifying the origin of head and neck squamous cell carcinoma in patients with cancer that has…
- Trial name
- NCT03868020
- Testing
- Computed Tomography, Fluciclovine F18, Positron Emission Tomography
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- M.D. Anderson Cancer Center
Sarcoidosis
Optimizing Acquisition Parameters and Interpretive Methods of FDG-PET/CT With Rb-82
In this this investigation, 15 subjects with a high probability of cardiac sarcoidosis based on clinical criteria and abnormal cardiac FDG uptake on initial, clinically indicted FDG PET study will be considered for this study.
- Trial name
- NCT03048097
- Testing
- Fluorodeoxyglucose, Rubidium, FDG-PET/CT with Rb82 Myocardial Perfusion Imaging
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Cardiac Amyloidosis
The Potential Role of 18F-NaF PET/CT in Diagnosing Cardiac Amyloidosis
Cardiac amyloidosis is a common cause of refractory cardiomyopathy and heart failure in an adult population. There are several types of cardiac amyloidosis, but two are the most common (1): A. AL - Light chain sunset. B.
- Trial name
- NCT04146480
- Testing
- F18-NaF PET/CT
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pheochromocytoma, Paraganglioma
In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma
This study will enroll up to 30 evaluable patients with pheochromocytoma or paraganglioma who are undergoing surgical or systemic treatment.
- Trial name
- NCT05636540
- Testing
- [18F]FluorThanatrace ([18F]FTT)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Heather Wachtel
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