Clinical trials: PET-CT
Myeloma Multiple
Prospective Comparison of 18F-choline PET/CT and 18F-FDG PET/CT in the Initial Work-up of Multiple Myeloma
Multiple myeloma (MM) survival has been improved during the last decade owing to new treatments. Hence, it has become a matter of importance to precisely define the depth of MM response to therapy.
- Trial name
- MYELOCHOL (NCT03891914)
- Testing
- Positron Emission Tomography using 18F-FCH, Positron Emission Tomography using 18F-FDG
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Primary Aldosteronism
Baxdrostat and Molecular Imaging of Adrenal Cytoreduction in Primary Aldosteronism
The goal of this clinical trial is to find out whether treatment with baxdrostat changes aldosterone-producing activity in the adrenal glands of people with primary aldosteronism.
- Trial name
- EliXir (NCT07800858)
- Testing
- baxdrostat
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- Queen Mary University of London
Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
PET Scan and CT Scan in Evaluating Response in Patients Undergoing Radiofrequency Ablation for Lung Metastases
RATIONALE: Radiofrequency ablation uses a high-frequency, electric current to kill tumor cells. Diagnostic procedures, such as PET scan and CT scan, may help doctors measure the patient's response to treatment.
- Trial name
- TEPARF (NCT00382252)
- Testing
- computed tomography, positron emission tomography, radiofrequency ablation
- Where
- 3 sites in France
- Volunteers
- 89 people
- Sponsor
- Institut Bergonié
Tumor, Brain
Multi-parametric MRI/Fluorine-18 Fluciclovine PET-CT in Glioblastoma
Glioblastoma is the most common adult brain tumour with approximately 2000 new cases each year in the UK. Optimal treatment consists of surgery followed by radiotherapy and chemotherapy but despite this survival is poor with only…
- Trial name
- NCT03409549
- Testing
- Fluciclovine PET/CT
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Esophageal Cancer, Esophageal Carcinoma
Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19
Esophageal cancer radiotherapy requires accurate delineation of the gross tumor volume (GTV) to ensure adequate tumor coverage and to minimize radiation dose to surrounding organs at risk.
- Trial name
- NCT07416825
- Testing
- Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography/Computed Tomography (PET/CT)
- Where
- Slovenia
- Volunteers
- 23 people
- Sponsor
- Institute of Oncology Ljubljana
Chest Pain
Investigating the Role of Active Versus Chronic Coronary Artery Calcification on Acute Myocardial Infarct
The investigator aims to determine the feasibility of understanding the process of active versus chronic calcification using Na-F PET scan and contrast CT scan of the heart.
- Trial name
- Active-AMI (NCT03712020)
- Volunteers
- 15 people
- Sponsor
- National Heart Centre Singapore
Prostate
POSLUMA® (18F-rhPSMA-7.3) PET-CT for PIRADS 2/3 Lesions
The goal of this study to determine if using the (18)F-rhPSMA-7.3 PET-CT scan can improve the ability to spot serious prostate cancer in patients who have uncertain MRI results.
- Trial name
- NCT07220720
- Testing
- Flotufolastat F 18
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Metabolic Preparation, Myocardial Inflammation
Impact of 100mL Lipid Emulsion for Intravenous for Suppression of Myocardial Glucose Metabolism in 18F-FDG PET/CT
There is increasing evidence that [18F]-2-fluoro-2-deoxy-D-glucose (18F-FDG) PET/CT is useful in the identification and treatment of disease processes that involve cardiac inflammation and infection.
- Trial name
- NCT04437927
- Where
- Monaco
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Princesse Grace
Non-Small Cell Lung Cancer
Role of PET CT in Determining Target Volumes in Radiation Therapy for Lung Cancer
Radiation therapy is an important part of the treatment for lung cancer when treatment intent is for cure. Radiation is a local modality of treatment, that is, it only treats the area that the radiation can target.
- Trial name
- NCT00221169
- Testing
- Surgical resection
- Where
- 2 sites in Canada
- Volunteers
- 31 people
- Sponsor
- Toronto Sunnybrook Regional Cancer Centre
Squamous Cell Carcinoma
Phase 0 of 18F FPM Using PET/CT in Patients With a Variety of Malignancies
The purpose of this study is to investigate the safety and potential effectiveness of the imaging compound 18F FPM for finding sites of malignancies.
- Trial name
- NCT01755650
- Testing
- 18F FPM
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Head and Neck Cancer
Validation of FDG-PET Segmentation Tools for Tumor Delineation by Correlation of CT- and FDG-PET Volume Measurements With Histopathology of Nodal Metastases of Head and Neck Carcinomas.
Various methods of FDG-PET signal segmentation will be validated by correlation of histopathologically measured tumor dimensions in lymph node dissection specimens of head-and-neck cancer patients.
- Trial name
- NCT00782691
- Testing
- CT-FDG/PET scan of the head-and-neck region
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Radboud University Medical Center
Muscle-Invasive Bladder Carcinoma, Bladder Cancer
Interest of Late Images for the Assessment of Extensions in 18FGD PET-CT of Muscle-Invasive Bladder Cancers
The goal of this study is to demonstrate a significant gain in sensitivity versus surgical curage (extended pelvic) for initial lymph node staging of late FDG-PET images (2.5 hours) versus standard images (1 hour), analyzed by…
- Trial name
- TARDITEP (NCT06537960)
- Testing
- 18FDG PET-CT
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Hopital Foch
Unknown Primary Tumor
Positron Emission Tomography - Computed Tomography (PET-CT) Scan as a Diagnostic Method in Unknown Primary Tumors
Is PET-CT scan better than PET or CT alone in diagnosing primary tumours in patients with unknown primary tumors? Can information obtained with PET-CT replace other clinical and radiological investigations? Is PET/CT…
- Trial name
- NCT00269373
- Testing
- PET-CT
- Where
- Denmark
- Volunteers
- 136 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostate Cancer
18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer
The main purpose of this phase II trial study is to determine whether a positron emission tomography (PET)/computed tomography (CT) scan using 18F-DCFPyL affects the clinical management plan in Veterans.
- Trial name
- PROSPYL (NCT04390880)
- Testing
- 18F-DCFPyL
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Prostate Cancer
Optimizing Prostate Cancer Treatment in Men With Advanced Local Disease
Multi-modality therapy that includes a brachytherapy implant improves outcomes in locally advanced prostate cancer when compared to other radiation-based treatments, but is also associated with more adverse side effects.
- Trial name
- OPTiMAL (NCT03836196)
- Testing
- LDR Brachytherapy and External Beam Radiation Therapy
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- British Columbia Cancer Agency
Tumor
68Ga-FAP-RGD PET/CT : Dosimetry and Preliminary Clinical Translational Studies
As an new dual targeting PET radiotracer, 68Ga-FAP-RGD is promising as an excellent imaging agent applicable to various cancers.
- Trial name
- NCT05515783
- Testing
- 68Ga-FAP-RGD
- Where
- China
- Volunteers
- 70 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Coronary Artery Disease
Rubidium-82 PET and Tc-99m-MIBI SPET: A Head to Head Comparison
The main purpose of this study is to compare myocardial perfusion imaging using Rubidium-82 PET with Tc-99m-MIBI SPET, in the evaluation of significant Coronary Artery Disease (CAD).
- Trial name
- NCT01379677
- Testing
- Rubidium-82, Sestamibi. reconstitution with sodium pertechnetate (99mTc)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Advanced Accelerator Applications
Primary Hyperparathyroidism, Primary Hyperparathyroidism Due to Adenoma
A Retrospective Analysis of the Diagnostic Performance of 11C-choline PET/CT in Primary Hyperparathyroidism
The leading cause of primary hyperparathyroidism (pHPT) is a solitary adenoma (89%). The treatment of pHPT is generally surgical removal of the overactive parathyroid gland(s).
- Trial name
- NCT04608253
- Testing
- 11C-choline PET/CT
- Volunteers
- 36 people
- Sponsor
- University Medical Center Groningen
Prostate Cancer
A Study of 68Ga-GRP PET/CT for Imaging in Low and Intermediate Risk Prostate Cancer
Patients with primary low and intermediate risk prostate cancer (PCa) for whom radical prostatectomy are indicated, will be invited to participate to the present study.
- Trial name
- NCT05073653
- Testing
- 68Ga-PSMA PET/CT, 68Ga-GRP PET/CT
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiangya Hospital of Central South University
NSCLC
18F-FDG PET/CT to Evaluate pD-1 Monoclonal Antibody With First-line Chemotherapy in Advanced NSCLC
This study is a diagnostic study. Subjects were enrolled from clinical stage IIIB or IV NSCLC patients who received standard first-line chemotherapy combined with PD-1 monoclonal antibody immunotherapy and received 18F-FDG PET/CT…
- Trial name
- NCT04996927
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
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