Clinical trials: PET-CT
Prostate Cancer
Digital PET/CT Using [Ga-68]PSMA vs. [F-18]NaF for Evaluation of Osseous Metastatic Involvement in Prostate Cancer Patients
The purpose of this study is to evaluate a radioactive diagnostic study drug, which is called Gallium-68 Prostate Specific Membrane Antigen ([Ga-68]PSMA) for detection of bone metastasis in patients with prostate cancer.
- Trial name
- NCT05527483
- Testing
- [68Ga]PSMA, Flourine-18 [F-18] Sodium Fluoride (NaF), PET/CT
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University Hospitals Cleveland Medical Center
Oral Cancer, Oropharyngeal Cancer
uPAR PET/CT for Staging Advanced and Localised Oral and Oropharyngeal Cancer
uPAR PET/CT for Staging Advanced and Localised oral and oropharyngeal cancer
- Conditions
- Oral Cancer, Oropharyngeal Cancer, Neoplasms, Head and Neck Neoplasms
- Trial name
- NCT02960724
- Testing
- 68Ga-NOTA-AE105 PET/CT
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lymphoma
Metabolic Insights: the Impact of F-18 FDG PET/CT in Adult Lymphoma
1. To assess staging accuracy of F-18 FDG PET/CT in lymphoma 2. Determine the role of F-18 FDG PET/CT in monitoring treatment response and detecting relapse or residual disease in lymphoma 3.
- Trial name
- NCT06737835
- Testing
- 18 FDG
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Neuroendocrine Tumors
68Ga-DOTATATE PET/CT in Neuroendocrine Tumor
Somatostatin receptor(SSTR) was expressed in neuroendocrine tumor cells and SSTR-targeting molecular imaging(68Ga-DOTATATE PET/CT) could be a promising technique to evaluate the primary tumor and metastatic lesions of…
- Trial name
- NCT04041882
- Testing
- 68Ga-DOTATATE
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Prostate Adenocarcinoma, Recurrent Prostate Carcinoma
Comparison of 18F-rhPSMA-7.3 PET/CT With and Without Furosemide in Biochemical Recurrence of Prostate Cancer
This phase II trial evaluates Fluorine-18 radiohybrid prostate-specific membrane antigen (18F- rhPSMA)-7.3 positron emission tomography (PET)/computed tomography (CT) scans with and without furosemide for the reduction of bladder…
- Trial name
- NCT05779943
- Testing
- Furosemide, F18-rhPSMA-7.3, Positron Emission Tomography
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Breast Cancer, Lung Cancer
18F-ASIS PET/CT Imaging of Tissue Factor Expression In Patients With Primary and Metastastic Cancer
The primary objective of the trial is to test the new radio tracer 18F-ASIS for PET imaging of tissue factor (TF) expression. The tracer has the potential of identifying tumors with high levels of TF expression, which is expected…
- Conditions
- Breast Cancer, Lung Cancer, Pancreatic Cancer, Ovarian Cancer
- Trial name
- NCT03790423
- Testing
- Injection of 18F-ASIS, PET/CT scan
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Nasopharyngeal Carcinoma
Combining PET/CT and EBV DNA to Evaluate the Hazard of Progression in the Follow-up of Locally Advanced NPC
PET/CT and EBV DNA are important in diagnosis of NPC. We consider that combining post-treament PET/CT and plasma EBV DNA may be effective in evaluating the hazard of progression in the follow-up of Locally Advanced Nasopharyngeal…
- Trial name
- NCT03601390
- Testing
- PET/CT and EBV DNA
- Where
- China
- Volunteers
- 387 people
- Sponsor
- Sun Yat-sen University
Carcinoma, Non-Small-Cell Lung
Surveillance With PET/CT and Liquid Biopsies of Stage I-III Lung Cancer Patients After Completion of Definitive Therapy
The purpose of this study is to improve early detection of treatable relapse of lung cancer and thereby improve survival and quality of life for the patients.
- Trial name
- SUPE_R (NCT03740126)
- Testing
- Whole body 18F-FDG PET/CT
- Where
- 3 sites in Denmark
- Volunteers
- 750 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostate Cancer
[18F]PSMA-11 PET/CT Phase 3 Clinical Study
Prostate cancer (PCa) is the most frequently occurring male cancer in Belgium. After treatment with surgery and/or radiotherapy, almost half of the patients suffer from a tumor recurrence, often diagnosed by an increase in serum…
- Trial name
- NGP3 (NCT03911310)
- Testing
- [18F]PSMA-11, [68Ga]PSMA-11
- Where
- Belgium
- Volunteers
- 96 people
- Sponsor
- University Hospital, Ghent
Endometriosis
The Role of FAPI PET-CT in Diagnosing Endometriosis
Patients with suspected endometriosis scheduled for surgery will be identified. They will be asked to participate in a study evaluating the feasibility of FAPI PET-CT in diagnosing endometriosis.
- Trial name
- NCT06792318
- Testing
- FAPI PET-CT
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Ziv Hospital
Tumour of Epithelial Origin, 68Ga-MY6349
A Study to Evaluate the Diagnostic Efficacy of 68Ga- MY6349 PET/CT in Patients With Tumours
This is a study using an autocontrol approach, enrolling 40 patients with tumours of epithelial origin, who underwent 68Ga- MY6349 and 68Ga-PSMA/18F-FDG PET/CT imaging of patients with tumours of epithelial origin to compare the…
- Trial name
- NCT06770478
- Testing
- 68Ga-MY6349 PET/CT Scan
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Rectal Cancer, Lymph Node Metastases
FDG - PET / MRI in Patients With Rectal Cancer
The combination of FDG-PET/CT and MRI at staging of rectal cancer in diagnosis is currently very little studied. The investigator have a unique opportunity to study this.
- Trial name
- RECTOPET (NCT03846882)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Region Västerbotten
Esophageal Cancer, Esophageal Carcinoma
Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19
Esophageal cancer radiotherapy requires accurate delineation of the gross tumor volume (GTV) to ensure adequate tumor coverage and to minimize radiation dose to surrounding organs at risk.
- Trial name
- NCT07416825
- Testing
- Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography/Computed Tomography (PET/CT)
- Where
- Slovenia
- Volunteers
- 23 people
- Sponsor
- Institute of Oncology Ljubljana
Prostate Cancer, Prostate Cancer Metastatic
The Diagnostic Value of FAPI PET/CT in Staging of Newly Diagnosed Prostate Cancer
This study aims to investigate the diagnostic value of FAPI PET/CT, relative to standard-of-care imaging using PSMA PET/CT, in staging of newly diagnosed PCa.
- Trial name
- proFAPI (NCT06634173)
- Testing
- FAPI PET/CT
- Volunteers
- 30 people
- Sponsor
- The Netherlands Cancer Institute
Colorectal Cancer, Metastatic Colorectal Cancer
Novel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal Cancer
This phase I/II trial studies the best dose and side effects of glutaminase inhibitor CB-839 and how well it works with panitumumab and irinotecan hydrochloride (phase I only) in treating patients with RAS wildtype colorectal…
- Conditions
- Colorectal Cancer, Metastatic Colorectal Cancer, RAS Wild Type Colorectal Cancer, Refractory Colorectal Cancer
- Trial name
- NCT03263429
- Testing
- Glutaminase Inhibitor CB-839, Panitumumab, Irinotecan Hydrochloride (phase I only)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Prostate Cancer
Optimizing Prostate Cancer Treatment in Men With Advanced Local Disease
Multi-modality therapy that includes a brachytherapy implant improves outcomes in locally advanced prostate cancer when compared to other radiation-based treatments, but is also associated with more adverse side effects.
- Trial name
- OPTiMAL (NCT03836196)
- Testing
- LDR Brachytherapy and External Beam Radiation Therapy
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- British Columbia Cancer Agency
Tumour
To Compare the Clinical Application of 18F-LNC1007 Injection PET/CT and 18F-FDG PET/CT
To evaluate the safety of 18F-LNC1007 injection in the diagnosis of suspected tumor, initial stage, or recurrence monitoring; to explore the biological distribution of 18F-LNC1007 injection in patients; To compare the diagnostic…
- Trial name
- 18F-LNC1007 (NCT06205888)
- Testing
- 18F-LNC1007（18F-FAPI-RGD） PET/CT和18F-FDG PET/CT
- Sponsor
- Jinling Hospital, China
Triple Negative Breast Cancer
Imaging Performance Assessment of 89Zi-girentuximab (89Zr-TLX250) PET in Metastatic Triple Negative Breast Cancer
The purpose of this study is to evaluate the use of 89Zr-labeled girentuximab (89Zr-TLX250) as a novel, carbonic anhydrase IX (CAIX) targeted PET/CT tracer for the imaging of metastatic triple negative breast cancer (TNBC)…
- Trial name
- OPALESCENCE (NCT04758780)
- Testing
- 89Zr-TLX250
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Institut Cancerologie de l'Ouest
Anatomic Stage IV Breast Cancer AJCC v8, Invasive Breast Lobular Carcinoma
Fluciclovine and PSMA PET/CT for the Classification and Improved Staging of Invasive Lobular Breast Cancer
This phase I trial studies how well fluciclovine positron emission tomography (PET)/computed tomography (CT) and PSMA PET/CT work in helping doctors understand and classify invasive lobular breast cancer in patients with invasive…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Invasive Breast Lobular Carcinoma, Metastatic Breast Lobular Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT04750473
- Testing
- Computed Tomography, Fluciclovine F18, Gallium Ga 68 Gozetotide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
HCC
18F-FDG PET in HCC Patients Candidate to Treatment With Sorafenib
The principal objective of this study is to explore the role of 18F-FDG PET in identifying sorafenib-induced metabolic shift in HCC, thus in predicting treatment response and disease outcome in advanced HCC patients candidate to…
- Trial name
- NCT02977754
- Testing
- This is an observational study
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Istituto Clinico Humanitas
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