Clinical trials: PICS
Critical Illness Recovery, Behavioral Health Concerns
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
This pilot study evaluates the feasibility and acceptability of implementing a Behavioral Health Collaborative Care Model (BH CoCM) for family members of ICU survivors.
- Conditions
- Critical Illness Recovery, Behavioral Health Concerns, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT07390786
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Post Intensive Care Syndrome (PICS)
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome
The goal of this clinical trial is to evaluate the effectiveness of a hypnosis intervention in improving well-being at day 28 of an ICU stay.
- Trial name
- HypnoPICS (NCT07254299)
- Testing
- Hypnosis
- Where
- 2 sites in Switzerland
- Volunteers
- 150 people
- Sponsor
- COEN Matteo
Post Intensive Care Syndrome, PICS
Impact of a COVID-19 Related ICU Stay on Mental Health for Patients and Their Relatives
As ICU mortality has been significantly decreased over the last two decades, the focus has been shifting from short term (such as ICU and hospital mortality) to long-term outcome.
- Conditions
- Post Intensive Care Syndrome, PICS, COVID-19, Critically Ill
- Trial name
- PICOVIDS (NCT05348720)
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- General Hospital Groeninge
Chronic Central Serous Chorioretinopathy
Steroid Eye Drops in Chronic Central Serous Chorioretinopathy
In this pilot study the effect and safety of the use of steroid eye drops in chronic central serous chorioretinopathy (cCSC) will be evaluated. The study is conducted as a randomized single-blind placebo-controlled trial.
- Trial name
- PICS (NCT05633576)
- Testing
- steroid eye drops
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
COVID-19, Post Intensive Care Syndrome
Aerobic Exercise and Covid-19 Survivors With Post-Intensive Care Syndrome (Pics)
To investigate the effects of aerobic exercise program on physical activity, aerobic capacity, anxiety\& depression in Covid-19 survivors discharged from Intensive Care Unit.
- Trial name
- NCT05341648
- Testing
- Aerobic Exercise Training, Home Plan
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
PICS
Impact of Persistent Inflammation-Immunosuppression-Catabolism Syndrome (PICS) on the Respiratory Physiology in Patients With Prolonged Mechanical Ventilation
Past research on PICS has mainly focused on the predictability and prognosis of PICS occurrence in ICU patients. Still, there is currently insufficient research on the role of PICS in the care setting of patients who have…
- Trial name
- NCT07002710
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Post Intensive Care Syndrome (PICS)
Pharmacist-Intensivist Collaborative Telehealth for Post-Intensive Care Syndrome
The goal of this pilot randomized controlled trial is to determine if a randomized controlled trial of a collaborative pharmacist-intensivist telehealth follow-up after intensive care unit discharge can feasibly be performed in…
- Trial name
- NCT06983496
- Testing
- Post-ICU Telehealth Follow-up
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Malcom Randall VA Medical Center
Anxiety, Depression
Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological Outcomes
This study will evaluate whether a systematically delivered, patient-oriented real time communication via aloud real time readings of ICU diary entries during patient's ICU stay is feasible
- Conditions
- Anxiety, Depression, PTSD
- Trial name
- NCT04510272
- Testing
- Aloud Real-time Reading of ICU Diaries
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Post-Intensive Care Syndrome (PICS)
ICU Biobank: Understanding Post-Intensive Care Syndrome (PICS)
The goal of this observational study is to explore the development and progression of Post-Intensive Care Syndrome (PICS) in adult ICU patients by establishing a biobank of biological samples and outcome data.
- Trial name
- NCT06671795
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Post Intensive Care Syndrome (PICS), PTSD - Post Traumatic Stress Disorder
ICU-VR Prior to ICU Admission
Rationale: A substantial proportion of the Intensive Care Unit (ICU) survivors develop psychological impairments due to their ICU admission.
- Trial name
- NCT06642636
- Testing
- Intensive Care Unit-specific Virtual Reality
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Denzel Drop
Critical Illness, Intensive Care (ICU) Myopathy
Muscle Dysfunction in Critical Illness
Patients surviving critical illness suffered significant skeletal muscle dysfunction and weakness that impacts their functionality and independence.
- Conditions
- Critical Illness, Intensive Care (ICU) Myopathy, PICS, Muscle Weakness
- Trial name
- NCT03717831
- Testing
- Observational study of standard of care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Kentucky
Post-Intensive Care Syndrome (PICS), Critical Illness
Inflammatory and Genetic Predictors of Cognitive and Emotional Recovery After Critical Illness
Survivors of critical illness frequently develop persistent cognitive and emotional impairments, known as post-intensive care syndrome (PICS), which substantially impact quality of life and long-term recovery.
- Trial name
- CORE-ICU (NCT07659431)
- Volunteers
- 114 people
- Sponsor
- Corporacion Parc Tauli
Critical Illness, Post Intensive Care Syndrome (PICS)
Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)
This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS).
- Conditions
- Critical Illness, Post Intensive Care Syndrome (PICS), Cardiopathy
- Trial name
- CARDIO-PICS (NCT07599306)
- Testing
- Tele-rehabilitation, Standard of Care
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Critical Illness
User Experience of a Telemedicine Platform for the Follow-up of Post Intensive Care Syndrome (PICS)
Survivors of critical illness may present with a set of physical, emotional and cognitive sequelae, known as Post Intensive Care Syndrome (PICS).
- Trial name
- NCT06438380
- Volunteers
- 14 people
- Sponsor
- Corporacion Parc Tauli
COVID-19, Critical Illness
REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19
Multicenter, prospective, randomized controlled trial providing mobile health supported physical rehabilitation to 120 patients who have been critically ill with COVID-19 and who complete at least one exercise session.
- Conditions
- COVID-19, Critical Illness, ICU Acquired Weakness, PICS
- Trial name
- REMM-HIIT-CoV (NCT05218083)
- Testing
- REmotely monitored, Mobile health supported Multidomain Rehabilitation Program with High Intensity Interval Training (REMM-HIIT)
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Duke University
PICS, Anxiety
Behavioral Health Collaborative Care Model in an ICU Recovery Clinic
Survivors of critical illness are at high risk for mental health issues such as anxiety, depression, and PTSD. This single-site, randomized controlled trial at the Medical University of South Carolina will enroll 150 patients to…
- Conditions
- PICS, Anxiety, Depression - Major Depressive Disorder, Post-Traumatic Stress
- Trial name
- BeColM (NCT07372586)
- Testing
- Behavioral Health Collaborative Care Model
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Delirium, Critical Illness
Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors
Older adults are at risk for ICU-acquired cognitive decline discernible from clinical, biological, and imaging- related changes in the brain following delirium and critical illness.
- Conditions
- Delirium, Critical Illness, Drive
- Trial name
- DRIVE-PICS (NCT05999903)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Baylor Research Institute
Postintensive Care Syndrome
Analysis of a Short Assessment of Post Intensive Care Syndrome (PICS)
To present a proposal for a set of outcome measurement instruments (OMIs) of post intensive care syndrome (PICS) in settings of outpatient healthcare service.
- Trial name
- NCT04175236
- Where
- 2 sites in Germany
- Volunteers
- 9 people
- Sponsor
- Claudia Spies
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health
Post Intensive Care Syndrome (PICS), Polypharmacy
The Critical Care Recovery Program: Use of a Structured Clinic Visit to Reduce Adverse Drug Events in ICU Survivors
Background and Objective: Intensive Care Units (ICUs) save lives, but many ICU survivors face ongoing health issues, including adverse drug events (ADEs) from medications started during their hospital stay.
- Conditions
- Post Intensive Care Syndrome (PICS), Polypharmacy, Adverse Drug Events, Critical Care, Intensive Care
- Trial name
- CCRP (NCT06723860)
- Volunteers
- 3,000 people
- Sponsor
- University of British Columbia