Clinical trials: PICS
COVID, Corona Virus Infection
Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to COVID-19
COVID-19 patients with a severely symptomatic progression with development of an Acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 need prolonged intensive care treatment involving pharmacological immobilization…
- Conditions
- COVID, Corona Virus Infection, Sars-CoV2
- Trial name
- NCT04397172
- Testing
- Study Arm
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke
Penumbra Imaging Collaborative Study (PICS)
The primary aim of this study are to gather data on the "real world" experience of the Penumbra System and to determine if there is a correlate between the imaging-defined size of the ischemic penumbra at admission and patient…
- Trial name
- PICS (NCT00785161)
- Testing
- Penumbra System
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Penumbra Inc.
Sepsis
Project 4B: Lower Extremity Strength Training in ICU Patients
The purpose of this research study is to see if electrical stimulation of the leg muscles will improve strength in patients receiving mechanical ventilation in the intensive care unit (ICU).
- Trial name
- NCT02467023
- Testing
- Muscle stimulation with Niveus medical stimulator, measurement of maximal isometric twitch strength, Muscle Biopsy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida
Post Intensive Care Syndrome, ARDS: Acute Respiratory Distress Syndrome
Combined Activity and Cognitive Intervention for ICU Survivors
This mixed-methods study comprising a 3-arm pilot RCT and a qualitative study aims to investigate the preliminary effects and feasibility of a home-based combined activity and cognitive intervention for ICU survivors…
- Conditions
- Post Intensive Care Syndrome, ARDS: Acute Respiratory Distress Syndrome, Delirium, Loss of Muscle Mass
- Trial name
- NCT06117761
- Testing
- Home-based exercises combined with cognitive training, Home-based exercises
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Critical Care, Intensive Care, Critical Illness
Dosage of Early Rehabilitation of ICU Patients
Rehabilitation already begins in the intensive care unit (ICU) to maintain or restore the functional capacity of ICU patients and to counteract the long-term effects of intensive care treatment.
- Conditions
- Critical Care, Intensive Care, Critical Illness, Physiotherapy, Early Ambulation
- Trial name
- ERUPT (NCT06960642)
- Where
- Austria
- Volunteers
- 6,000 people
- Sponsor
- Medical University of Vienna
Critical Illness, COVID-19
A Study of Healthy Microbiome, Healthy Mind
Researchers are doing this study to find out if a high fermented food diet is tolerable, and if it will help improve quality of life after surviving a critical illness, including severe COVID-19, by promoting gut health recovery…
- Conditions
- Critical Illness, COVID-19, PICS, Cognitive Impairment
- Trial name
- NCT06020703
- Testing
- Fermented Food Diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Post-Intensive Care Syndrome (PICS)
MONITOR-IC: Determining and Improving Long-term Consequences of ICU Care
Due to advances in critical care medicine, more patients survive their critical illness. However, intensive care unit (ICU) survivors often experience long-term physical, cognitive and mental problems, summarized as post…
- Trial name
- MONITOR-IC (NCT03246334)
- Where
- Netherlands
- Volunteers
- 50,000 people
- Sponsor
- Radboud University Medical Center
Surgical Site Infections
Prevention of Infections in Cardiac Surgery (PICS) Prevena Study
This vanguard study will be conducted at two study sites in Canada. It is a cluster randomized trial to test a combination of two antibiotics for antibiotic prophylaxis as compared to routine prophylaxis with one single…
- Trial name
- PICS-Prevena (NCT03402945)
- Testing
- Prevena, Cefazolin, Vancomycin
- Where
- 2 sites in Canada
- Volunteers
- 4,107 people
- Sponsor
- Population Health Research Institute
Anemia Postoperative
A Clinical Trial Assessing the Efficacy of Intravenous Iron for the Treatment of Anemia Following Cardiac Surgery
BACKGROUND Anemia and iron deficiency are highly prevalent in cardiac surgery patients. Both conditions may adversely affect postoperative rehabilitation.
- Trial name
- PICS (NCT04608539)
- Testing
- Ferric Derisomaltose, Ferrous sulfate, normal saline
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Michael Kremke
Sepsis
Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty
The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis.
- Trial name
- NCT02711709
- Testing
- Frailty Measurements, Modified Minnesota Leisure Time Activities, Computed tomography morphometrics
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Florida
Sepsis, Long Term Care
Long-Term Recovery and Quality of Life in Sepsis Survivors
The goal of this observational study is to learn about the long-term outcomes and recovery of adult patients admitted to the intensive care unit (ICU) with sepsis.
- Conditions
- Sepsis, Long Term Care, Sepsis Scores, Long Term Follow-Up
- Trial name
- UNCOVER (NCT07863128)
- Testing
- Care for Sepsis
- Where
- Switzerland
- Volunteers
- 530 people
- Sponsor
- University of Geneva, Switzerland
Infection, Surgical Site
Prevention of Infections in Cardiac Surgery (PICS): a Cluster-randomized Factorial Cross-over Trial
The goal of this pragmatic, multi-centre factorial cluster randomized cross-over trial is to assess the efficacy of a combination of cefazolin plus vancomycin compared to cefazolin monotherapy, as well as a comparison of short…
- Trial name
- PICS (NCT06567808)
- Testing
- Cefazolin, Vancomycin
- Volunteers
- 38,000 people
- Sponsor
- Hamilton Health Sciences Corporation
Post Intensive Care Syndrome (PICS)
Surviving the Pediatric Intensive Care Unit (PICU)
Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness.
- Trial name
- NCT06812130
- Testing
- This is a non-interventional study.
- Where
- 2 sites in Singapore
- Volunteers
- 404 people
- Sponsor
- KK Women's and Children's Hospital
Intensive Care Unit Syndrome, Disabilities Multiple
Post-Intensive Care Transitional Care, Rehabilitation, and Family-Support
The goal of this randomized control trial is to test an intervention designed to improve patient and family outcomes after critical illness compared to usual care.
- Conditions
- Intensive Care Unit Syndrome, Disabilities Multiple, Critical Illness, Caregiver Burden
- Trial name
- PIC-TRFS (NCT06501365)
- Testing
- Post Intensive Care Transitions Rehabilitation and Family Support (PIC-TRFS), Enhanced Usual Care Control
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pittsburgh
Post Intensive Care Syndrome (PICS)
SOcioeconomics Status and Post-Intensive Care Syndrome
Intensive care units provide care for patients with multiple organ failure, with the aim (over and above survival) of guaranteeing an acceptable quality of life after resuscitation and proportionate care in accordance with the…
- Trial name
- SOPICS (NCT06697236)
- Testing
- EPICES score, PICS evaluation, PICS-F evaluation
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Post-ICU Patients, PICS
Measuring the Effects of Music-Listening On Distress After Intensive Care
The primary goal of this single-case experimental design study is to investigate the effectiveness of personalised music listening on daily levels of distress after discharge from a critical care ward.
- Trial name
- MELODIC (NCT07762196)
- Testing
- Music intervention
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Edinburgh
Post-Intensive Care Syndrome (PICS), Symptom Burden
Post-Intensive Care Syndrome and Associated Symptom Burden Among Danish ICU Survivors
The study aims to estimate the prevalence of post-intensive care syndrome (PICS) 12 months after ICU admission among adult ICU survivors in Denmark and to describe how this prevalence is distributed across the physical…
- Conditions
- Post-Intensive Care Syndrome (PICS), Symptom Burden, Intensive Care Unit (ICU) Patients
- Trial name
- PICAS-DK (NCT07373561)
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Post-Intensive Care Syndrome (PICS)
Post-ICU Syndrome and Social Determinants of Healths
Medical intensive care has improved dramatically, and today, 70% to 80% of critically ill patients survive. However, several survivors face long-term psychological, cognitive, and/or physical sequelae after discharge and…
- Trial name
- NCT07828301
- Where
- 5 sites in Chile
- Volunteers
- 400 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Cancer, Psycho-Oncology
What Impact Does an Initial Psycho-oncological Contact Have on People With Cancer?
When diagnosed with cancer, patients or their relatives may, if they wish, on the recommendation of the treatment team and/or in cases of high stress, seek psycho-oncological support.
- Trial name
- PICS (NCT07544446)
- Testing
- initial psycho-oncological contact, Standard
- Where
- 5 sites in Switzerland
- Volunteers
- 148 people
- Sponsor
- Lindenhofgruppe AG
Gut Microbiota, PICS
Intestinal Flora Research Plan for Critically Ill Patients
More and more critically ill patients have improved early survival, they have been suffering from organ damage and inflammation for a long time, which is called chronic critical illness (CCI).
- Trial name
- NCT04455061
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese Medical Association