Clinical trials: PRP
Osteo Arthritis Knee, Platelet-rich Plasma
Platelet Rich Plasma for Knee Osteoarthritis
This study aimed to analyze the effect of platelet-rich plasma (PRP) on knee osteoarthritis. Eligible patients will undertake arthroscopic knee surgery plus intraoperative PRP and also receive second look surgery and…
- Trial name
- NCT03197441
- Testing
- Platelet-rich plasma
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Pei-Yuan Lee, MD
Temporomandibular Joint Disorders
Postoperative Assessment of Platelet-Rich Plasma and Platelet-Rich Fibrin in Temporomandibular Joint Surgery
The goal of this observational study is to evaluate postoperative outcomes following temporomandibular joint (TMJ) surgery and to compare the effectiveness of intraoperative platelet-rich plasma (PRP) and platelet-rich fibrin…
- Trial name
- NCT07359131
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Jingping Wang, MD, Ph.D.
Osteoarthritis, Knee
Steroids, Hyaluronic Acid or Platelet Rich Plasma Versus Placebo for the Knee Osteoarthritis
This study investigates clinical outcome and imaging outcome parameters after intraarticular injection of steroids, platelet-rich-plasma (prp), hyaluronic acid or placebo in patients with early osteoarthritis of the knee joint.
- Trial name
- KIT (NCT02776514)
- Testing
- Triamcort, Platelet-rich-plasma, Suplasyn1
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Balgrist University Hospital
Shoulder Pain, Musculoskeletal Diseases
The Efficacy of PRP Injection in the Treatment of Rotator Cuff Syndrome
The aim of this study is to investigate the efficacy of single PRP injection compared with placebo and multiple PRP injections on pain, quality of life, shoulder function and muscle strength in the treatment of patients who have…
- Conditions
- Shoulder Pain, Musculoskeletal Diseases, Rotator Cuff Tendinopathy, Rotator Cuff Syndrome
- Trial name
- PRP (NCT05561452)
- Testing
- Single PRP Injection, Multiple PRP Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Afyonkarahisar Health Sciences University
Diabetic Retinopathy
Pattern Laser Versus Conventional Laser in Diabetic Retinopathy
Purpose: To evaluate the clinical efficiency, safety and painfulness of retinal laser photocoagulation employing a pattern scanning laser system Pascal given in a single-session versus conventional laser multiple-session…
- Trial name
- NCT03672656
- Testing
- lasercoagulation by Pascal system, conventional laser
- Volunteers
- 30 people
- Sponsor
- University Hospital Ostrava
Unilateral Cleft Lip
Effect of Platelet Rich Plasma (PRP) on the Esthetic Outcome and Scar Formation of Unilateral Cleft Lip Repair
The purpose of this study is to evaluate effect of platelet rich plasma on scar formation of unilateral cleft lip repair.
- Trial name
- NCT02958306
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Diabetic Foot Ulcers, Diabetic Wound
The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
The aim of this study is to evaluate the chance of non-healing diabetic foot ulcers repair by improving the condition of lack of oxygen or hypoxia in the wound area caused by diabetes using methylene blue along with the use of…
- Trial name
- NCT05850611
- Testing
- Methylene Blue, Milk (control), Methylene Blue and Platelet-Rich Plasma-Fibrin Glue
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Atrophic Acne Scar
Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars
This study is to test the efficacy of fractional laser combined with either PRP fluid or PRP gel in the treatment of atrophic acne scars
- Trial name
- PRP (NCT04580758)
- Testing
- Fractional laser with PRP fluid or PRP gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Yasmine Ahmed Abd El-Maguid El-Hadidy
Temporomandibular Joint Osteoarthritis
Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder
Temporomandibular joint (TMJ) disorders are health conditions that can occur at any age and are recognized as the most common cause of chronic pain, affecting 5-12% of the population.
- Trial name
- NCT06839326
- Testing
- Autologous Conditioned Serum, Genesis Biyomedikal, Sanakin®-Acrs produce, Platelet Rich Plasma, Control Group/ Only Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Batman University
Patients with Jaw Muscles Myofascial Pain
A Comparative Study on the Impact of Trigger Points Injection of Platelet Rich Plasma Versus Botulinum Toxin on the Relief of Jaw Muscles Myofascial Pain
This study aims at comparing the effect of trigger points injection of platelet rich plasma and botulinum toxin a on the relief of jaw muscles Myofascial pain .
- Trial name
- NCT06814535
- Testing
- Botulinum Toxin A / Botulinum Toxin A, Platelet rich plasma
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Supraspinatis Interstitial Partial-thickness Tears, Platelet-rich Plasma (PRP)
In Vivo Clinical and Radiological Effects of Platelet-rich Plasma on Interstitial Supraspinatus Lesion: Randomized Study
Background and Rationale: Tedious PRP infiltrations are emerging treatments for tendinopathies and tendon tears. It has been showed effective in different parts of the body, but current evidences for rotator cuff PRP infiltration…
- Trial name
- PRP Randomized (NCT02672085)
- Testing
- PRP infiltraiton, Needling
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- La Tour Hospital
Ankle Osteoarthritis
A Single Intraarticular Injection of Platelet-Rich Plasma on Pain and Physical Function in Patients With Ankle OA
Platelet-rich plasma (PRP) has been reported to be an effective treatment for knee osteoarthritis (OA). The application in ankle OA has rarely been investigated.
- Trial name
- NCT04022928
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
COVID-19
Pulmonary Rehabilitation Program With Pulsed Electromagnetic Field Therapy in Patients With Post-covid Sequelae.
Coronavirus 2019 disease can cause important sequelae in the patient, being one of the main affectations of the respiratory system due to bilateral pneumonia and frequently presenting loss of strength, dyspnea, polyneuropathies…
- Trial name
- NCT05379517
- Testing
- Pulsed ectromagnetid field therapy, Pulmonary rehabilitation program (PRP)
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- University of Malaga
Aging
Evaluation of the Mechanism of Action of Platelet Rich Fibrin Matrix (PRFM) in Producing Skin Volume Augmentation
Autologous platelet rich fibrin matrix will release growth factors which could increase the production of dermal proteins or affect the vascularity and status of neighboring tissues.
- Trial name
- NCT00956020
- Testing
- Platelet rich fibrin matrix
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Diabetic Macular Edema
Efficacy & Safety Trial of Intravitreal Injections Combined With PRP for CSME Secondary to Diabetes Mellitus (DAVE)
This study is a Phase I/II, multicenter, randomized, study of the efficacy and safety of ranibizumab injection monotherapy verses a duel therapy of 0.3mg ranibizumab combined with ultra wide, 200° field angiography guided pan…
- Trial name
- DAVE (NCT01552408)
- Testing
- 0.3 mg ranibizumab, Targeted Pan Retinal Photocoagulation
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- David M. Brown, M.D.
Lumbar Herniated Disc
Assesment of Epidural Platelet-Rich Plasma (PRP) Injection During Uniportal Endoscopic Lumbar Disc Herniation Excision on Residual Neuropathies
The aim of this study is to assess neuropathic pain in the lower limb at 6 months post-operation in patients who have undergone surgery for a lumbar disc herniation using single-port endoscopic discectomy combined with an…
- Trial name
- HERDISPLA (NCT07770750)
- Testing
- Uniportal endoscopic lumbar disc herniation removal
- Where
- France
- Volunteers
- 50 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Genitourinary Syndrome of Menopause
Management of Cancer Therapy Related Vulvovaginal Atrophy
The goal of this clinical trial is to: 1. evaluate the efficacy of PRP injection and PRP injection mixed with non-cross-linked hyaluronic acid compared to the control group receiving standard therapy with topical non-cross-linked…
- Trial name
- NCT05782920
- Testing
- Platelet rich plasma, non cross-linked hyaluronic acid, topical HA gel
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
Anterior Cruciate Ligament Reconstruction
Effect of PRP Versus BMC in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) is an important stabilizer of knee during daily activity and exercise. The ruptured ACL need to be reconstructed by a new tendon graft which passed the bone tunnel and joint during operation.
- Trial name
- NCT05191732
- Testing
- Platelet-Rich Plasma; Bone marrow concentrate
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Meningitis, Epiglottitis, Pneumonia, Arthritis Caused by Haemophilus Influenzae Type b
Persistency Study After Hib-CRM (Cross-Reacting Material)197 or Hib-TT (Tetanus Toxoid) Vaccines in Chinese Children
Evaluate the persistency of immune response against Haemophilus influenzae type b by assessing anti-PRP antibody levels in children vaccinated with either Hib-CRM197 or Hib-TT booster vaccine approximately 4 years before.
- Trial name
- NCT02139228
- Testing
- Hib-CRM197, Hib-TT
- Where
- China
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Baker's Cyst
PRP vs Corticosteroid in Baker's Cyst
This is a Prospective study with Randomized patients into either Ultrasound-guided Platelets-Rich-Plasma injection and Ultrasound guided Corticosteroid Injection, with 3 months and 6 months follow ups after aspiration at our…
- Trial name
- NCT02249377
- Testing
- Platelets-Rich-Plasma, Corticosteroid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health