Clinical trials: PRP, open to volunteers
Peyronies Disease
Platelet-Rich Plasma for Peyronie's Disease
The purpose of this clinical trial is to evaluate the effects of Platelet-Rich Plasma (PRP) intralesional injections in men affected by Peyronie's disease (PD) in the fibrotic phase.
- Trial name
- NCT07117955
- Testing
- Autologous Platelet Rich Plasma, Saline solution
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Herlev Hospital
Peripheral Nerve Injury Upper Limb
Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study
The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults.
- Trial name
- NCT06638008
- Testing
- perineural injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Pain, Perioperative
Reducing Pain From Retinal Laser With Vibrational Stimulation
The goal of this clinical trial is to learn if Vibration Anesthesia Device works to reduce pain during retinal laser for diabetic retinopathy.
- Trial name
- NCT06649604
- Testing
- Vibration Anesthesia Device, Panretinal Photocoagulation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Persistent Epithelial Defect
Autologous Platelet-rich Plasma in the Treatment of Persistent Epithelial Defects
Persistent epithelial defects (PED) are corneal ulcers that do not heal within the first two weeks of treatment with artificial tears or ocular lubricant ointment.
- Trial name
- NCT03653650
- Testing
- PRP plus BCL, BCL plus PFL, Eye patch plus ocular lubricant ointment
- Where
- Mexico
- Volunteers
- 54 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Reproductive Issues
The Efficacy and Safety of Female PRP Co-incubation With Sperm During (IUI) Cycles
The investigators hypothesize that infertility patients undergoing IUI who receive female autologous platelet-rich plasma (PRP) co-incubation with husband's sperm would have higher clinical pregnancy rate.
- Trial name
- NCT07615634
- Testing
- non-PRP group (control group), PRP group (intervention group)
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Chinese University of Hong Kong
Knee Osteoarthritis, Knee Osteoarthritis (Knee OA)
Efficacy of Platelet-Rich Plasma Added to Hyaluronic Acid in Knee Osteoarthritis
This prospective, randomized, open-label, single-centre post-market clinical follow-up (PMCF) study evaluates the clinical performance and safety of a single intra-articular injection of hyaluronic acid (HA) combined with…
- Conditions
- Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
- Trial name
- NCT07785401
- Testing
- Hyaluronic Acid (HA) and Platelet rich plasma (PRP), Hyaluronic Acid (HA)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Implai Sp z o.o
Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs)
Platelet-Rich Plasma for Partial Rotator Cuff Tears
The goal of this clinical trial is to learn whether platelet-rich plasma (PRP) injection, made from a participant's own blood, can help heal the tendon and improve shoulder symptoms in people with partial tears of the…
- Conditions
- Partial Supraspinatus Tear, Rotator Cuff Tears (RCTs), Rotator Cuff Injury
- Trial name
- OPTIMISE (NCT07659600)
- Testing
- Platelet-Rich Plasma (PRP) Injections
- Volunteers
- 100 people
- Sponsor
- Universidade Nova de Lisboa
Chronic Non-healing Skin Ulcers
PRP Versus PRF Versus Conventional Treatment in Chronic Non-healing Skin Ulcers
To compare the therapeutic efficacy of PRP and PRF: two relatively newer modalities in the management of chronic non-healing ulcers versus conventional treatment.
- Trial name
- NCT06281483
- Testing
- platelet-rich plasma, platelet-rich fibrin, Surgical debridement, normal saline washing and dressing coverage
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University
Paraosmia
Randomized Clinical Trial of Intranasal Injection of Platelet-Rich Plasma for Treatment of Parosmia
This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PRP) in the treatment of qualitative olfactory dysfunction (parosmia).
- Trial name
- NCT06283745
- Testing
- Platelet-rich Plasma (PRP), Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Acetabular Labrum Tear, Femoro Acetabular Impingement
Use of BMAC With Hip Arthroscopy Treatment of FAI and Labral Tear
Femoro-acetabular impingement is a well known cause of damage to the acetabular labrum and chondrolabral junction. Additionally, it has been proposed that disruption of hip biomechanics resulting from a labral tear causes a…
- Conditions
- Acetabular Labrum Tear, Femoro Acetabular Impingement, Chondral Defect, Bone Marrow Aspirate Concentrate
- Trial name
- NCT03909139
- Testing
- BMAC
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Acetabular Labrum Tear, Femoro Acetabular Impingement
Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies
The goal of this clinical trial is to assess the effect of PRP/PPP/BMAC application on functional outcomes after hip arthroscopy to address acetabular labral pathologies. The main questions it aims to answer are: 1.
- Conditions
- Acetabular Labrum Tear, Femoro Acetabular Impingement, Chondral Defect, Bone Marrow Aspirate Concentrate
- Trial name
- PRP; PPP; BMAC (NCT06003101)
- Testing
- Bone marrow aspirate concentrate (BMAC), Control
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Vocal Fold Sulcus ,Scar and Atrophy
Vocal Fold Injection by Platelet Rich Plasma
a study to asses safety and efficacy of platelet rich plasma injection in some types of vocal fold problems such as sulcus and atrophy to see the improvement in patient voice and its impact on patient quality of life with a good…
- Trial name
- NCT07350642
- Testing
- injection of platelet rich plasma, Nasofiberoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Plantar Fasciitis, Heel Pain
Baxter's Nerve Pulsed Radiofrequency Versus Platelet-Rich Plasma Injection or Both Together as a Treatment Modality of Recalcitrant Plantar Fasciitis
Plantar fasciitis is a common condition causing chronic heel pain due to degenerative changes in the tissue supporting the arch of the foot.
- Conditions
- Plantar Fasciitis, Heel Pain, Nerve Compression Syndromes
- Trial name
- NCT07826234
- Testing
- Baxter's Nerve Pulsed Radiofrequency, Autologous Platelet-Rich Plasma Injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Knee Arthritis Osteoarthritis, Platelet Rich Plasma Injection
Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)
The effects of single dose injection of platelet rich plasma or conditioned serum in the knee joint in patients with knee osteoarthritis will be compared
- Conditions
- Knee Arthritis Osteoarthritis, Platelet Rich Plasma Injection, Conditioned Serum
- Trial name
- KOA PRP ACS (NCT07473232)
- Testing
- Autologous Platelet-Rich Plasma (PRP), Conditioned serum (CS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Diabetic Foot Ulcer, Type 1 Diabetes Mellitus
Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.
The goal of this investigational study is to evaluate the safety and clinical performance of Tropocells Autologous Platelet-rich Fibrin (PRF) for wound care for both males and females, ages 18-80 years old, with Grade 1 and 2…
- Conditions
- Diabetic Foot Ulcer, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM), Neuroischemic Foot Ulcer
- Trial name
- NCT06810726
- Testing
- Platelet Rich Plasma
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Estar Medical dba Medical Technologies, LTD
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Proliferative Diabetic Retinopathy, Diabetic Retinopathy
Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in working-age adults. The current gold standard treatment for PDR is panretinal photocoagulation (PRP).
- Conditions
- Proliferative Diabetic Retinopathy, Diabetic Retinopathy, Diabetic Retinopathy Visually Threatening, Diabetic Macular Edema
- Trial name
- SMART-PRP (NCT06549023)
- Testing
- Single-session panretinal PRP (SS-PRP), Multiple-session panretinal PRP (MS-PRP)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Panretinal Photocoagulation
Effect of Argon Laser Panretinal Photocoagulation on Corneal Endothelial Cell Density .
This study investigates the effect of argon laser panretinal photocoagulation (PRP) on the corneal endothelial cell density (ECD) in patients with proliferative diabetic retinopathy (PDR) by comparing ECD measurements before and…
- Trial name
- NCT07157553
- Volunteers
- 45 people
- Sponsor
- Assiut University
Poor Ovarian Response, Ovarian Reactivation
Proteomic and Biological Characterisation of Plasma for the Study of Changes Following Ovarian Reactivation Treatment
The samples used in PRGF treatments owe their effectiveness to the handling, concentration, and preservation of their components, which explains why samples obtained with different platelet-rich plasma preparation systems may…
- Trial name
- NCT07376460
- Testing
- Platelet Rich Plasma + BMDSCs mobilization
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Knee Osteoarthritis, PRP Injection
Comparing the Efficacy of Lyophilized Self Growth Factor Versus PRP Injection for Knee OA
Knee osteoarthritis(OA) is a common degenerative joint disease that often leads to knee pain, stiffness, and a decline in quality of life among middle-aged and elderly individuals.
- Trial name
- NCT06932614
- Testing
- Lyophilized self growth factor, Platelet-Rich Plasma(PRP)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Tri-Service General Hospital (TSGH)