Clinical trials: PTSD, completed
PTSD (Childbirth-Related)
Preventing Childbirth-Related PTSD With Expressive Writing
The goal of this clinical trial is to test a brief psychological intervention given to individuals in the first days following childbirth who have experienced a potentially stressful childbirth.
- Trial name
- CARES (NCT05662423)
- Testing
- Expressive Writing about Childbirth, Neutral Writing
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Child Sexual Abuse, Post-Traumatic Stress Disorder, PTSD
Intensive Inpatient Trauma-Focused Cognitive Behavioral Therapy (II-TF-CBT) for Adolescents With PTSD Following Sexual Abuse
This study looks at a treatment program for children and teens who have post-traumatic stress disorder (PTSD) after sexual abuse. The program is called II-TF-CBT.
- Trial name
- NCT07732335
- Testing
- II-TF-CBT
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
PTSD
The Effectiveness of Group-Delivered Guided Written Exposure Therapy for PTSD and CPTSD Among Adolescents : A Pilot Study
The study aims to examine the effectiveness of group-delivered guided written exposure therapy (GWE) for post-traumatic stress disorder (PTSD) and complex PTSD in Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT06403449
- Testing
- Group-delivered guided written exposure therapy, Waiting-List (WL) condition
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Peking University
Posttraumatic Stress Disorder (PTSD), Trauma and Stressor Related Disorders
EMDR Group Therapy for Posttraumatic Stress Symptoms in Migrants
The goal of this randomized controlled trial is to evaluate the effectiveness and feasibility of the Eye Movement Desensitization and Reprocessing Integrative Group Treatment Protocol for Ongoing Traumatic Stress (EMDR-IGTP-OTS)…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Trauma and Stressor Related Disorders, Psychological Distress
- Trial name
- NCT07731906
- Testing
- Integrative Group Treatment Protocol for Ongoing Traumatic Stress (EMDR-IGTP-OTS)
- Where
- Italy
- Volunteers
- 185 people
- Sponsor
- Azienda Sanitaria Locale Salerno
PTSD, Alcohol Use Disorder
Oxytocin to Enhance Integrated Treatment for AUD and PTSD
The primary objective of the proposed Stage II study is to examine the efficacy of oxytocin (OT) as compared to placebo in reducing (1) alcohol use disorder (AUD) symptoms, and (2) post-traumatic stress disorder (PTSD) symptoms…
- Trial name
- COPE+OT (NCT04523922)
- Testing
- 40 IU Intranasal Oxytocin, Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Medical University of South Carolina
PTSD, Post Traumatic Stress Disorder
Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD)
This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.
- Trial name
- NCT06868446
- Testing
- OTX-601 Digital Therapeutic - Version 1, OTX-601 Digital Therapeutic - Version 2, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oui Therapeutics, Inc.
Trauma, PTSD
Key Dimensions of PTSD and ED
This study will test whether endothelial dysfunction could be the early subclinical mechanism by which posttraumatic stress disorder (PTSD) increases cardiovascular disease (CVD) risk, and whether posttraumatic fear-a key…
- Conditions
- Trauma, PTSD, Endothelial Dysfunction
- Trial name
- NCT03778307
- Testing
- Psychophysiological fear conditioning and extinction task, Eyetracking task
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of California, Los Angeles
Posttraumatic Stress Disorder (PTSD), Sleep Disturbances and Insomnia
A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances
Post-traumatic stress disorder (PTSD) affects many people who have experienced traumatic events. A common issue with PTSD is severe sleep disturbances, such as nightmares.
- Trial name
- PTSD-PoC (NCT06685965)
- Testing
- RE03
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Reconnect Labs
PTSD, Trauma
Neuroendocrine Risk for PTSD in Women
This study will test for effects of estradiol (E2) on PTSD symptoms and functional magnetic resonance imaging (fMRI) indicators of stress vulnerability, in naturally-cycling women who are not using hormonal birth control.
- Trial name
- NCT03973229
- Testing
- Estradiol patch
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Emory University
PTSD
Peer-led Trauma Therapy for Re-entry
The purpose of the research is to learn more about how to treat PTSD for people directly impacted by incarceration (i.e., have spent time in prison or jail).
- Trial name
- NCT06019767
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Wisconsin, Madison
PTSD
Intranasal Insulin for Posttraumatic Stress Disorder
To evaluate if intranasal insulin is effective in reducing PTSD symptoms.
- Trial name
- NCT04044534
- Testing
- Intranasal insulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Connecticut Healthcare System
Major Depressive Disorder, Depression
Testing a Transdiagnostic TMS Treatment Target
The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder.
- Conditions
- Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders
- Trial name
- T5 (NCT06282146)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Posttraumatic Stress Disorder (PTSD)
Mindfulness-based Stress Reduction for PTSD in Road Traffic Accident Victims: A Randomized Controlled Trial
The goals of the study are to investigate the effects of mindfulness-based stress reduction (MBSR) on PTSD among road traffic accident victims.
- Trial name
- NCT07521020
- Testing
- mindfulness-based stress reduction
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Universiti Sains Malaysia
Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder
EMDR Flash Group Protocol for Earthquake Survivors
This pilot randomized controlled trial evaluated the preliminary effects of the online EMDR Flash Group Protocol among adults affected by the 2023 Kahramanmaraş earthquakes in Türkiye.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder, Anxiety, Depression
- Trial name
- FlashGP-EQ (NCT07672613)
- Testing
- EMDR Flash Group Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
PTSD
Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD
Posttraumatic Stress Disorder (PTSD) is a common and serious condition affecting many Veterans. There are effective treatments for PTSD, but additional treatments are needed in order to better serve Veterans suffering from PTSD.
- Trial name
- rTMS for PTSD (NCT04207346)
- Testing
- TMS 1 hz
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
PTSD, Cannabis-Related Disorder
Functional Outcomes of Cannabis Use (FOCUS) in Veterans With Posttraumatic Stress Disorder
Posttraumatic stress disorder (PTSD) is a disabling psychiatric disorder that affects 20%-30% of U.S. Veterans. PTSD is strongly associated with increased risk for substance abuse comorbidity, including cannabis use disorder.
- Trial name
- FOCUS (NCT04565028)
- Testing
- Contingency Management (CM)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder (PTSD)
Identification of Markers of Post-Traumatic Stress Disorder (PTSD) Relapse
Relapse of post-traumatic stress disorder (PTSD) remains challenging. In addition, factors predicting PTSD relapse are still unknown.
- Trial name
- NCT01545505
- Testing
- Neuropsychological assessment
- Where
- 4 sites in France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
PTSD - Post Traumatic Stress Disorder
Psychiatric Nurse-Delivered Eye Movement Desensitization and Reprocessing (EMDR) for Adults With Post-Traumatic Stress Symptoms in Jordan
Here is a plain-language, registry-appropriate Brief Summary you can paste into the form. It is written for patients, families, and healthcare providers: Brief Summary This study examines whether Eye Movement Desensitization and…
- Trial name
- Experimental (NCT07423832)
- Testing
- EMDR
- Where
- Jordan
- Volunteers
- 70 people
- Sponsor
- Al-Quds University
Posttraumatic Stress Disorder (PTSD), Anxiety
Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women
Trauma exposure, posttraumatic stress disorder (PTSD), and substance use disorder (SUD) present major threats to public health. PTSD and SUD are major correlates of disability, often resulting in severe social and occupational…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Anxiety, Depression - Major Depressive Disorder
- Trial name
- MSC for PTSD (NCT06646692)
- Testing
- Mindful Self Compassion, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of California, Los Angeles
Depression, Anxiety
REstoring Mental Health Through COmmUnity-based Psychological Services in New York City
The goal is to improve mental health. The study will evaluate the impact of community-based mental health services. Successful completion of this study will contribute to the National Institute of Mental Health Strategic Plan…
- Conditions
- Depression, Anxiety, Psychological Distress, PTSD
- Trial name
- RECOUP-NY (NCT04913766)
- Testing
- Problem Management Plus, Services as Usual
- Where
- United States
- Volunteers
- 1,206 people
- Sponsor
- George Washington University