Clinical trials: PTSD, completed
Major Depressive Disorder, PTSD
McLean and Genomind Prospective Study
This is a three month naturalistic prospective, randomized, open label study of pharmacogenetic testing and clinical outcomes in inpatients across diagnoses, including Treatment Resistant Depression (TRD) with or without…
- Trial name
- GPS (NCT03113890)
- Testing
- Phlebotomy - Folate, Cheek Swab, Self-report surveys
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mclean Hospital
COVID-19 Pandemic
A Coping and Resilience Intervention in Adolescents
The primary purpose of this study is to assess the feasibility and acceptability of a coping and resilience intervention for adolescents in school settings named CERIA, in the post-coronavirus disease 2019 or COVID-19 era.
- Trial name
- CERIA (NCT05830188)
- Testing
- Coping and Resilience Intervention for Adolescents, Printing materials of Coping and Resilience Intervention for Adolescents
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Major Depressive Disorder, Post Traumatic Stress Disorder
ALTO-100 in MDD and/or PTSD
The goal of this study is to collect biologically based data for defining predictors and correlates of the effects of ALTO-100.
- Trial name
- NCT05117632
- Testing
- ALTO-100 PO tablet
- Where
- 23 sites in United States
- Volunteers
- 245 people
- Sponsor
- Alto Neuroscience
Gambling Disorder, Trauma, Psychological
Online Coping Skills Counseling for Problem Gambling and Trauma
This randomized controlled trial examines the efficacy of two behavioral therapies. Seeking Safety, which addresses co-occurring problem gambling (PG) and posttraumatic stress disorder (PTSD), is being compared to…
- Conditions
- Gambling Disorder, Trauma, Psychological, Problem Gambling, Posttraumatic Stress Disorder
- Trial name
- NCT03145792
- Testing
- Seeking Safety, CBT for Pathological Gambling
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Windsor
Posttraumatic Stress Disorder
MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder
The goal of this clinical trial is to compare MDMA-assisted therapy to placebo with therapy in people with chronic, treatment-resistant posttraumatic stress disorder (PTSD).
- Trial name
- NCT00090064
- Testing
- Midomafetamine HCl, Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Resilient Pharmaceuticals
Emotions, Memory Deficits
Brain Response to Treatment for Pediatric PTSD
This study will examine how brain activation changes as a result of behavioral treatment for posttraumatic stress disorder (PTSD) in adolescents.
- Conditions
- Emotions, Memory Deficits, Post-traumatic Syndrome
- Trial name
- NCT01806701
- Testing
- Trauma-focused cognitive behavioral therapy
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Stanford University
Posttraumatic Stress
PTSD Coach Sweden: Evaluating a Self-help Mobile App for Posttraumatic Stress in a Community Sample
Individuals who experience potentially traumatic events might develop long-lasting mental health problems. Limitations to health care resources, particularly in the context of mass disasters, indicate that self-help interventions…
- Trial name
- NCT04094922
- Testing
- Swedish PTSD Coach smartphone app
- Where
- Sweden
- Volunteers
- 174 people
- Sponsor
- Uppsala University
Post Traumatic Stress Disorder
An Evaluation of the Long-term Efficacy and Safety of Methylone for the Treatment of PTSD
This is an extension study of participants who previously completed a Transcend-sponsored clinical trial evaluating TSND-201 as a treatment for PTSD. Participants will be followed for up to 52 weeks.
- Trial name
- IMPACT-EXT (NCT06237426)
- Testing
- Methylone
- Where
- 9 sites in United States, Ireland and 1 more
- Volunteers
- 44 people
- Sponsor
- Transcend Therapeutics
Post-Traumatic Stress Disorder, Substance Use Disorders
Effectiveness of Peer-Delivered Trauma-Specific Treatment
Patient-Centered Trauma Treatment, i.e., treatment delivered by peers with lived-experience, has the potential to increase access to trauma treatment in underserved communities.
- Trial name
- NCT02081417
- Testing
- Seeking Safety
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- University of New Mexico
Psychotic Disorders, Psychological Trauma
Prevalence of Traumatic Events and PTSD in Immigrant and Non-immigrant Patients With Psychotic Disorder
Higher rates of psychosis are described in migrant population. Likewise, this populations could suffer several adversities during migration process that could lead to higher exposure to traumatic events and higher rates of…
- Conditions
- Psychotic Disorders, Psychological Trauma, Stress, Psychological, Cross-Cultural Comparison
- Trial name
- NCT04867447
- Testing
- Psychological trauma evaluation
- Where
- Spain
- Volunteers
- 199 people
- Sponsor
- Parc de Salut Mar
PTSD, PTSD - Post Traumatic Stress Disorder
Efficacy of Eye Movement Desensitization and Reprocessing (EMDR) Therapy Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in the Treatment of Post-Traumatic Stress Disorder
This randomized controlled trial aims to compare the efficacy of Eye Movement Desensitization and Reprocessing (EMDR) therapy versus Selective Serotonin Reuptake Inhibitors (SSRIs) in the treatment of Post-Traumatic Stress…
- Trial name
- NCT06955845
- Testing
- Eye Movement Desensitization and Reprocessing Therapy, Selective serotonin reuptake inhibitors
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Asad Ullah Jan
Stress Disorders, Post-Traumatic
Acupuncture for the Treatment of Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to evaluate acupuncture as a treatment for Post-Traumatic Stress Disorder (PTSD) and to correlate the diagnosis of PTSD with Traditional Chinese Medicine (TCM) diagnostic patterns.
- Trial name
- NCT00055354
- Testing
- Acupuncture, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
PTSD
Paroxetine Treatment in Outpatients With Comorbid PTSD and Substance Dependence
Pharmacotherapy has demonstrated efficacy in a number of controlled trials in the treatment of PTSD. The selective serotonin reuptake inhibitors have proven particularly useful in treating this disorder.
- Trial name
- NCT00330239
- Testing
- Paroxetine CR
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical University of South Carolina
Combat Disorders, Posttraumatic Stress Disorder
Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms
The goals of the proposed research are to produce preliminary evidence of PE with OEF/OIF veterans with PTSD and to examine cognitive, psychophysiological, and neuroendocrine mechanisms of change in PTSD treatment.
- Trial name
- NCT00475241
- Testing
- Prolonged Exposure therapy for PTSD, Present centered therapy for PTSD
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Post-Traumatic Stress Disorder (PTSD)
TraumaRelief App: A Pilot RCT Assessing Feasibility and Acceptability
The world experiences a high rate of traumatic events. Even if PTSD is not diagnosed, traumatic events can significantly affect people's lives.
- Trial name
- NCT06288594
- Testing
- Application Plus Online Therapist Support Group, Application Only Group
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Dokuz Eylul University
Combat Disorders, Stress Disorders, Post-Traumatic
Motivational Interviewing to Engage Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans in Mental Health Treatment
The goal of this randomized controlled trial is to evaluate the efficacy of telephone-administered motivational interviewing (TAMI) to enhance VA mental health treatment engagement among veterans of Operations Enduring Freedom…
- Conditions
- Combat Disorders, Stress Disorders, Post-Traumatic, Depression, Substance-Related Disorders
- Trial name
- NCT00419029
- Testing
- telephone-administered motivational interviewing, control
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Post-Traumatic Stress Disorder
KIDNET Versus Meditation/Relaxation - a Dissemination RCTT for Children in Sri Lanka Traumatized by the War and the Tsunami
The purpose of this study is to assess the efficacy of KIDNET versus a Meditation/Relaxation protocol in treating traumatized children in Sri Lanka when applied by locally trained teacher counsellors.
- Trial name
- NCT00820391
- Testing
- KIDNET, Meditation-Relaxation
- Volunteers
- 31 people
- Sponsor
- University of Konstanz
Critical Illness, Covid19
Psychological Impact of COVID-19 Outbreak on Caregivers
Based on the experience of previous pandemics, countries reacted by applying different upgrade strategies to prevent or delay the widespread of the disease.
- Conditions
- Critical Illness, Covid19, Stress Disorders, Post-Traumatic
- Trial name
- PSY-CO-ICU (NCT04511780)
- Testing
- questionnaire filling
- Where
- 51 sites in France
- Volunteers
- 701 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
PTSD
PTSD Treatment for Incarcerated Men and Women
There is a particular need for more effective treatments for post-traumatic stress disorder (PTSD) within the incarcerated population.
- Trial name
- NCT03891797
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Wisconsin, Madison
PTSD
Prolonged Exposure and Oxytocin
Posttraumatic stress disorder (PTSD) is a chronic, debilitating anxiety disorder that may develop after direct or indirect exposure to traumatic events.
- Trial name
- NCT03238924
- Testing
- Oxytocin
- Volunteers
- 17 people
- Sponsor
- Medical University of South Carolina