Clinical trials: PTSD, completed
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-Traumatic Stress Disorders
Mechanistic Pathways of Mindfulness Meditation in Post-traumatic Stress Disorder.
The purpose of this study is to find out how meditation influences certain systems in the body: nervous system, hormonal system, and respiratory system.
- Trial name
- NCT00778960
- Testing
- Slow Breathing, Meditation, Meditation and slow breathing
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Oregon Health and Science University
HIV, AIDS
Intervention Program to Address PTSD in People Living With HIV
The goal of this randomised controlled trial is to evaluate the efficacy of an integrated intervention program on post-traumatic stress disorder (PTSD) symptoms and related physiological and psychological indicators of people…
- Conditions
- HIV, AIDS, Mindfulness-based Stress Reduction, China
- Trial name
- NCT05588596
- Testing
- Trauma Resiliency Mindfulness-Informed Intervention
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Central South University
Post Traumatic Stress Disorder, Family
Psychological Impact in a Relative, Following the Announcement of the Death of a Loved One After Cardiac Arrest and the Early Request for Organ Donation
The fight against the scarcity of grafts is a major public health issue in France. Despite a very good success rate of transplants from brain-dead donors or living donors, the waiting time for transplantation continues to…
- Conditions
- Post Traumatic Stress Disorder, Family, Psychological Distress, Organ and Tissue Procurement
- Trial name
- REPERPSY (NCT03721770)
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- frederic ADNET
Stress Disorders, Post-Traumatic
Treatment of Post-Traumatic Stress Disorder (PTSD) in Sexually Abused Children
The purpose of this study is to compare the effectiveness of two psychological therapies used to treat PTSD in children who have recently been sexually abused: Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) vs Child…
- Trial name
- NCT00000383
- Testing
- Trauma-Focused CBT, Child-Centered Therapy
- Where
- 3 sites in United States
- Volunteers
- 229 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
PTSD, Trauma
Neuroendocrine Risk for PTSD in Women
This study will test for effects of estradiol (E2) on PTSD symptoms and functional magnetic resonance imaging (fMRI) indicators of stress vulnerability, in naturally-cycling women who are not using hormonal birth control.
- Trial name
- NCT03973229
- Testing
- Estradiol patch
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Emory University
Traumatic Brain Injury
CONcussion Treatment After Combat Trauma (CONTACT)
This study compares the effects of Individualized Scheduled Telephone Support (ISTS) and Usual Care (UC) for service members with Mild Traumatic Brain Injury (mTBI). A total of 400 service members will participate in this study.
- Trial name
- CONTACT (NCT01387490)
- Testing
- Individualized Scheduled Telephone Support (ISTS), Usual Care (UC)
- Where
- 4 sites in United States
- Volunteers
- 366 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Dissociative Identity Disorder, Dissociative Disorder Not Otherwise Specified (DDNOS)
"Finding Solid Ground" in Inpatient Treatment for Dissociative Disorder Patients Followed by Transition to Outpatient Treatment Settings: A 1-year Follow-up Pilot Study
The purpose of the pilot is to examine the usefulness of the psychoeducational program, Finding Solid Ground, for patients with dissociative disorders in a naturalistc observational study, involving a 3-months inpatient treatment…
- Conditions
- Dissociative Identity Disorder, Dissociative Disorder Not Otherwise Specified (DDNOS), PTSD and Trauma-related Symptoms
- Trial name
- NCT07432646
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Modum Bad
PTSD
Ganaxolone in Posttraumatic Stress Disorder (PTSD)
This Phase 2 proof-of-concept study is a double-blind, randomized, placebo-controlled, 15-week investigation of ganaxolone versus placebo for the treatment of Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01339689
- Testing
- Ganaxolone
- Where
- 8 sites in United States
- Volunteers
- 112 people
- Sponsor
- Marinus Pharmaceuticals
Posttraumatic Stress Disorder, PTSD
D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 13-18…
- Trial name
- NCT01157429
- Testing
- D-cycloserine, CBT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Tulane University School of Medicine
Intimate Partner Violence, Depression
MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence
The purpose of this R34 exploratory research proposal is to conduct formative work for a larger randomized controlled trial (RCT) evaluating the effectiveness of the "Mother AdvocateS In the Community (MOSAIC) Plus" intervention…
- Conditions
- Intimate Partner Violence, Depression, Post Traumatic Stress Disorder
- Trial name
- MOSAIC Plus (NCT05106361)
- Testing
- MOSAIC Plus, MOSAIC
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michigan State University
Chronic Pain, Depression
Comparing Acupuncture, BioModulator, and Transcutaneous Electrical Nerve Stimulation for Symptomatic Treatment of Chronic Pain.
The primary objective of this preliminary study is to compare the Tennant BioModulator with Transcutaneous Electrical Nerve Stimulation (TENS) and Traditional Chinese Acupuncture for the management of chronic pain among injured…
- Conditions
- Chronic Pain, Depression, PTSD Symptoms, Sleep
- Trial name
- NCT01752010
- Testing
- Traditional Chinese Acupuncture, Tennant™ Biomodulator Treatment, Transcutaneous electrical nerve stimulation (TENS) Treatment
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Samueli Institute for Information Biology
Posttraumatic Stress Disorder, Depression
The Pitt Center for Emergency Responder Wellness
Emergency responders protect the public despite occupational hazards that threaten their mental health. The Pitt Center for Emergency Responder Wellness will be a clinical innovation hub that: 1) delivers accessible interventions…
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
- Trial name
- NCT05357586
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Post-traumatic Stress Disorder, Depressive Disorder
Project SERVE: Post Deployment Functioning
Functional recovery is of the utmost importance to evaluate in our returning Operation Enduring and Iraqi Freedom Veterans so that we can better understand their needs and experiences during the readjustment process from warzone…
- Conditions
- Post-traumatic Stress Disorder, Depressive Disorder, Alcoholism
- Trial name
- NCT01123642
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Tinnitus, Traumatic Brain Injury
Investigating the Neurobiology of Tinnitus
The investigators hypothesize that individual differences exist in resting-state cortical attention, control, sensory, and emotion networks prior to noise exposure and these differences predispose some to the development of…
- Conditions
- Tinnitus, Traumatic Brain Injury, Post Traumatic Stress Disorder
- Trial name
- NCT01294124
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Posttraumatic Stress Disorder
Emotional Working Memory Training for Veterans With PTSD Symptoms
PTSD is characterized by recurrent intrusion of trauma-related memories and images that cause significant distress and impairment to the affected individuals.
- Trial name
- NCT02766296
- Testing
- Active Emotional Working Memory Training, Control Working Memory Training
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Milwaukee VA Medical Center
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
PTSD - Post Traumatic Stress Disorder
Neural Basis of the Effect of EMDR Therapy
This study aimed to investigate the effects of a single session of Butterfly Tapping (BT), a self-administered form of alternating bilateral stimulation, on emotional reactivity and its neurophysiological correlates.
- Trial name
- EMDR-NEURO (NCT07550556)
- Testing
- Butterfly Tapping (BT), No intervention control
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Rome Foro Italico
Borderline Personality Disorder, Posttraumatic Stress Disorder
CPT Group for DBT Clients With Co-Occurring Borderline Personality Disorder and PTSD
Even though borderline personality disorder (BPD) and posttraumatic stress disorder (PTSD) commonly co-occur, few studies have examined PTSD treatment among individuals with BPD.
- Trial name
- CPTDBT (NCT02574429)
- Testing
- Cognitive Processing Therapy
- Where
- 2 sites in Canada
- Volunteers
- 45 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Posttraumatic Stress Disorder, Major Depressive Disorder
Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD
This study is a randomized controlled trial comparing an integrated treatment, Behavioral Activation + Cognitive Processing Therapy (BA + CPT), to CPT alone among active-duty service members with posttraumatic stress disorder…
- Trial name
- NCT02874131
- Testing
- Behavioral Activation, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego