Clinical trials: PTSD - Post Traumatic Stress Disorder
PTSD
Delivery Considerations of Cognitive Processing Therapy for PTSD
Review treatment outcomes of modifications to standard delivery of CPT for PTSD that are delivered as routine care at in VA outpatient clinic.
- Trial name
- NCT04765319
- Testing
- CPT for PTSD
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- VA Salt Lake City Health Care System
PTSD and Trauma-related Symptoms, PTSD
A Pilot Research Project on Outcome of Trauma Informed Stabilization Treatment (TIST) for Adults with Complex Trauma Symptoms After Childhood Trauma, At the Department of Trauma Treatment, Modum Bad, Norway
The purpose of the study is to examine the effects of residential group and individual Trauma Informed Stabilization Treatment (TIST) for complex symptoms in adult survivors of childhood trauma in a naturalistic observational…
- Trial name
- NCT06719167
- Testing
- Psychoterapy
- Where
- Norway
- Volunteers
- 32 people
- Sponsor
- Modum Bad
Post-Traumatic Stress Disorder, Sleep Initiation and Maintenance Disorders
Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder
This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors.
- Trial name
- NCT00183430
- Testing
- Prazosin, Psychotherapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Post Traumatic Stress Disorder
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
This study addresses PTSD symptoms in First Responders and Healthcare workers. Specifically, it tests whether a brief PTSD treatment (talk therapy) effectively treats PTSD when provided to First Responders and Healthcare workers…
- Trial name
- NCT05751473
- Testing
- Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU)
- Where
- 14 sites in United States
- Volunteers
- 410 people
- Sponsor
- University of Michigan
Stress Disorders, Post-Traumatic
fMRI to Examine the Effect of CBTm to Increase Resiliency for PTSD
A substantial proportion of public safety personnel (PSP) develop service-related posttraumatic stress disorder (PTSD). PTSD is associated with a range of negative outcomes and its exact underlying neurophysiological mechanism is…
- Trial name
- NCT03998501
- Testing
- Cognitive Behavioral Therapy with Mindfulness Class
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Post-traumatic Stress Disorder (PTSD), Emotional Contagion
Attachment and Post-Traumatic Stress Disorder in Military Personnel: Characterization of the French Military Population, Exploration of Biopsychosocial Factors, and Study of the Impact of Security Priming on Emotional Contagion Capacities
Post-traumatic stress disorder (PTSD) is a pathology that impairs the quality of life of sufferers. In military personnel, it can lead to military incapacity.
- Trial name
- AT-HOME (NCT06996275)
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Posttraumatic Stress Disorder
A Controlled Breathing Course for Social & Emotional Health for Vietnam Veterans With Chronic PTSD-RCT
The main aim of this project is to evaluate the use of a specific Yoga technique of controlled breathing in Vietnam War Veterans with chronic posttraumatic stress disorder.
- Trial name
- NCT00256477
- Testing
- Sudarshan KRIYA Breathing Technique
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Post Traumatic Stress Disorder, Major Depressive Disorder
Primary-Care Based Mindfulness Intervention
The purpose of this study is to pilot a primary-care based mindfulness intervention for chronically traumatized African Americans screening positive for posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) in…
- Trial name
- NCT03922581
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Emory University
Stress Disorders, Post-Traumatic
An Immersion Intervention for Symptoms of PTSD in Student Veterans
This study will explore the physical and psychological effects of warm water immersion to the chest on student Veterans who experience symptoms of Post-Traumatic Stress Disorder (PTSD) and may also have depression, anxiety and…
- Trial name
- NCT05309031
- Testing
- Water Immersion
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Nevada, Las Vegas
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder, Major Depressive Disorder
Accelerated TMS to a Novel Brain Target in MDD and PTSD
This is a Clinical Trial designed to evaluate novel transcranial magnetic stimulation (TMS) methods for treating depression/PTSD. TMS is an FDA-approved procedure for treatment-resistant depression.
- Trial name
- NCT03114891
- Testing
- Transcranial Magnetic Stimulation (TMS), Task, fMRI-guided TMS target
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Alcohol Use Disorder, PTSD
Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
The project will examine whether a computerized neuroscience-based cognitive training program can improve cognitive functioning and recovery outcomes among Veterans with Alcohol Use Disorder and co-occurring PTSD.
- Conditions
- Alcohol Use Disorder, PTSD, Cognitive Dysfunction
- Trial name
- NCT02929979
- Testing
- Cognitive Training
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcohol Problems, Post-Traumatic Stress Disorder
The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans
Veterans seeking to improve their romantic relationships when high conflict and unhealthy dynamics (e.g., aggression) are present remain underserved within the VHA with few treatment options.
- Trial name
- ACT-SHARE (NCT06746727)
- Testing
- Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder
An Evaluation of the Long-Term Safety and Efficacy of TSND-201 for the Treatment of PTSD
This study is evaluating the long-term safety and efficacy of TSND-201 in adults with PTSD. Participants that have completed a double-blind clinical trial with TNSD-201 for PTSD will be invited to participate in this open-label…
- Trial name
- EMPOWER-EXT (NCT07670702)
- Testing
- TSND-201
- Where
- 17 sites in United States
- Volunteers
- 300 people
- Sponsor
- Transcend Therapeutics
Post Traumatic Stress Disorder
Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine
This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design.
- Trial name
- NCT05948553
- Testing
- Intervention A Fluoxetine Hydrochloride (HCl)
- Where
- 9 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Global Coalition for Adaptive Research
Psychological Trauma, PTSD
Study of Yoga and Mindfulness for Psychological and Physical Wellness
The study rationale is to analyze the extent to which adult U.S. or non U.S. veterans or active duty military personnel who participate in the Yoga for Men (YfM) online Yoga and meditation classes report changes in symptoms of…
- Trial name
- NCT03059095
- Testing
- Yoga & Meditation
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of South Florida
PTSD
Exploring Mechanisms of Massed Cognitive Processing Therapy
The overall goal of this randomized controlled trial with partial crossover is to compare the effectiveness of 1-week virtual massed Cognitive Processing Therapy (CPT) to 5-day virtual relaxation training (RT) with regard to…
- Trial name
- NCT05265039
- Testing
- Cognitive Processing Therapy, Relaxation Training
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
PTSD - Post Traumatic Stress Disorder
Virtual Reality and Post Traumatic Stress
Northern Ireland has a legacy of trauma-related mental health problems and a higher estimated prevalence of post-traumatic stress disorder (PTSD) than other comparable post-civil conflict societies.
- Trial name
- NCT06684977
- Testing
- 360 Video, VR Photoscan, Standard TF-CBT
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Queen's University, Belfast
Depression, PostTraumatic Stress Disorder
Study of Effectiveness and Implementation of a Mental Health Intervention With Conflict-affected Communities in Ukraine
This project aims to contribute to the development of a community mental health care system while directly serving the conflict affected population in east Ukraine.
- Trial name
- NCT03058302
- Testing
- CETA (Common Elements Treatment Approach)
- Where
- 3 sites in Ukraine
- Volunteers
- 302 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Traumatic Brain Injury, Post-Concussive Symptoms
Role of NSI in Differentiating Between Mild Traumatic Brain Injury And Behavioral Health Conditions
The purpose of this study is to examine differences in post-concussive (PC) symptom endorsement among four groups of Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) Veterans: those with a history of target…
- Conditions
- Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
- Trial name
- NCT01502839
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 887 people
- Sponsor
- VA Eastern Colorado Health Care System