Clinical trials: PULSE OXIMETRY
Oximetry
EmbracePlus SpO2 Accuracy Validation
The aim of this study is to test the accuracy of EmbracePlus computed SpO2 during mild, moderate and severe hypoxia (a lower-than-normal concentration of oxygen in arterial blood); ie, a range of arterial HbO2 saturations from…
- Trial name
- NCT04964609
- Testing
- EmbracePlus
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Empatica, Inc.
Oxygen Saturation
Hand Perfusion and Pulse Oximetry Performance
The purpose of this study is to compare oxygen saturation measurement readings from manufactured pulse oximetry devices to the oxygen saturation measurements of arterial blood samples drawn at the same time of measurements.
- Trial name
- NCT06925646
- Testing
- Finger hyperperfusion via adenosine, Finger hypoperfusion via by norepinephrine, Baseline hypoxic test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anesthesia
Opioid Free Anesthesia and Continuous Post-operative Pulse Oximetry Monitoring in the Obese Patient
Anaesthesia has three major components, analgesia, muscle relaxation and hypnosis. For a long time, opioids have been covering the analgesia function.
- Trial name
- NCT03124680
- Testing
- Opioid free, opioid group
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Université Libre de Bruxelles
Hypoxia, Pulse Oximetry
SpO2 Difference Between Fingers of the Hand During Sequential Desaturation and Step Resaturation
The aim of the project is to experimentally compare the fingers of the hand in terms of measured concentrations of peripheral blood oxygen saturation (SpO2) in healthy humans during gradual desaturation in the range of 60-100%…
- Conditions
- Hypoxia, Pulse Oximetry, SpO2
- Trial name
- StatDynSpO2 (NCT05681637)
- Testing
- Breathing mixtures of O2 and N2 and monitoring SpO2 on each finger
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Pregnancy, Abdominal
Feasibility of a Non-invasive, Trans-abdominal, Low Cost Fetal Oximetry Probe on Pregnant Human Subjects
Three non-invasive, trans-abdominal fetal oximetry probes will be tested on pregnant human subjects, in order to obtain fetal heart rate.
- Trial name
- NCT03013842
- Testing
- Raydiant Oximetry Sensor System
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, Davis
Childhood Severe Illness, Pneumonia
Tools for the Integrated Management of Childhood Illness: Cross-country Quasi-experimental Pre-post Study in Kenya and Senegal
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Childhood Severe Illness, Pneumonia, Primary Health Care, Hypoxia
- Trial name
- TIMCI (NCT05065320)
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 51,590 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Congestive Heart Failure, Cardiomyopathy
Comparison of Different Locations for Pulse Oximetry Probes in Cardiovascular (CV) Patients With Poor Peripheral Perfusion
The purpose of this study is to determine if the forehand location for sensor placement has less episodes of signal dropout than the finger sensor location.
- Trial name
- NCT01128036
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Saint Luke's Health System
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Oxygen Saturation Measurement
Controlled Desaturation Study for Perin Health Patch Validation
This study aims to test the accuracy of the Perin Health Patch (PHP), a non-invasive, chest-worn device that measures blood oxygen levels, by comparing its readings to a standard pulse oximeter device.
- Trial name
- NCT06680700
- Testing
- Perin Health Patch
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Perin Health Devices
Microcirculation, Photoplethysmography
Evaluation of Microcirculation With Photoplethysmography (Pulse Oximetry) in Healthy Volunteers and Ventilated Patients
The objective of this observational study is to explore microcirculation in healthy volunteers and in ventilated patients in the operating room and in critical care.
- Trial name
- NCT06141681
- Testing
- photoplethysmography
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Healthy Volunteers
Effects of Breath-Hold vs Standard Interval Training on Fitness in Mountaineers
This study investigated whether adding structured breath-holds to standard interval training improves cardiorespiratory fitness in recreational mountaineers more than interval training alone.
- Trial name
- NCT07703839
- Testing
- Voluntary Hypoventilation Training, Progressive Treadmill Interval Training
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammadreza Rezaeipour, MD, PhD
Critical Congenital Heart Disease
Health-economic Impact of Pulse Oximetry Systematic Screening of Critical Congenital Heart Disease in Asymptomatic Newborns
Persistant hypoxemia in the newborn confers, even isolated, an abnormal clinical situation, that needs to be addressed for an adequate diagnosis and an optimal treatment.
- Trial name
- OXYNAT (NCT03078218)
- Testing
- Pulse oximetry
- Where
- 29 sites in France
- Volunteers
- 44,140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Hypoxemia, Procedural Sedation
The Effectivity of End-tidal CO2 and Oxygen Reserve Index (ORI) Monitoring in Sedation
Endoscopic procedures are commonly performed using sedation. As drug-induced respiratory depression is a major cause of sedation-related morbidity, pulse oximetry has been established as standart practice .
- Conditions
- Hypoxemia, Procedural Sedation, Hypercapnia, Apnea
- Trial name
- NCT04793178
- Testing
- Oxygen Reserve Index, Masimo Corporation, USA.
- Volunteers
- 200 people
- Sponsor
- Yuksek Ihtisas Hospital
Pulse Oximetry Plethymographic Waveform, Area Under Curve
The Normal Reference Values of Pulse Oximetry Plethymographic Waveform Parameters
The purpose of this study is to determine the normal reference values of pulse oximetry plethymographic waveform parameters in Chinese population.
- Conditions
- Pulse Oximetry Plethymographic Waveform, Area Under Curve, Amplitude
- Trial name
- NCT02292420
- Where
- China
- Volunteers
- 1,019 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Hyperbilirubinemia, Neonatal Indirect
The Effect of Phototherapy Treatment on Oxygen Saturation Measurement in Newborns
This will be a prospective clinical study conducted with the approval of the Clinical Research Ethics Committee. The influence of phototherapy lights on the accuracy of pulse oximetry will be investigated.
- Trial name
- NCT04494217
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Bronchiolitis, Hypoxia
Intermittent Versus Continuous Pulse Oximetry Monitoring of Infants Admitted for Bronchiolitis
Bronchiolitis is a lower respiratory tract infection (LRTI) syndrome cause by different types of viruses and occurs in young children.
- Trial name
- NCT01014910
- Testing
- Continuous pulse oximetry monitoring, Intermittent pulse oximetry monitoring
- Where
- 4 sites in United States
- Volunteers
- 161 people
- Sponsor
- Children's Mercy Hospital Kansas City
Childhood Pneumonia, Hypoxemia
Assessing the Feasibility and Effectiveness of Introducing Pulse Oximetry in IMCI Services
The purpose of the study is to assess the feasibility, acceptability and operational challenges of introducing Pulse Oximeter (PO) in IMCI services to manage acute respiratory infections at first-level primary care facilities in…
- Trial name
- NCT03750747
- Testing
- Pulse Oximeter
- Where
- Bangladesh
- Volunteers
- 612 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pulmonary Embolism
A Simple Clinical Tool to Help Diagnose Pulmonary Embolism: Phase 1
The goal of this project is to determine if the change in oxygen saturation during deep inspiration ("augmented pulse oximetry") can be used as a method to rule out pulmonary embolism (PE).
- Trial name
- NCT01898637
- Testing
- Augmented pulse oximetry using incentive spirometer., Incentive spirometer.
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Mayo Clinic
Hypoxemia, Neonatal Disease
Evaluation of a Multi-country Medical Oxygen Program
REAL-MOXY is a set of 5 mixed methods studies designed to understand how oxygen and pulse oximetry are used (or not used) at a facility level, to identify opportunities and barriers for strengthening oxygen systems for…
- Conditions
- Hypoxemia, Neonatal Disease, Pneumonia, Sepsis
- Trial name
- REAL-MOXY (NCT06087315)
- Testing
- Multi-faceted oxygen systems strengthening interventions (different for each country)
- Where
- 3 sites in Cambodia, Nigeria and 1 more
- Volunteers
- 1,200 people
- Sponsor
- Murdoch Childrens Research Institute
Surgery, Arterial Catheterization, Peripheral
Feasibility of Obtaining Pulse Oximetry Readings From the Oropharynx
This is a prospective study to evaluate the feasibility of obtaining a pulse oximetry ready from the oropharynx with a standard oximeter probe that has been attached to an oral airway or a tongue blade.
- Trial name
- NCT05690633
- Testing
- Pulse oximetry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Joseph D. Tobias