Clinical trials: PULSE OXIMETRY
Hypoxia
RDS MultiSense® SpO2 Calibration
Data will be collected with the MultiSense® pulse oximetry system during non-motion conditions over the range of 70-100%. A Clinimark reference system, previously correlated to arterial blood CO-Oximetry will be the basis for…
- Trial name
- NCT05466942
- Testing
- Pulse Oximeter, Respiratory Rate, Heart Rate
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rhythm Diagnostic Systems
Hypoxemia, Desaturation of Blood
Alternate Methodology of Pulse Oximeter Validation
This study will determine if the replacement of the measured arterial blood oxygen saturation with expired (end-tidal) oxygen value is an acceptable method to calculate the accuracy of pulse oximeters.
- Trial name
- NCT03628560
- Testing
- RespirAct Step-Wise Normocapnia desaturation sequence, RespirAct Slope Normocapnia desaturation sequence, RespirAct Step-Wise Hypocapnia desaturation sequence
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Duke University
Collect Blood Values With Induced Hypoxia, Induced Methemoglobinemia, and Induced Hypoxia and Methemoglobinemia
Accuracy of Detection of Methemoglobin With Pulse Oximetry
The non-invasive measurement of dysfunctional hemoglobins allows physicians to monitor levels in affected individuals without requiring blood samples or laboratory testing.
- Trial name
- NCT03869840
- Testing
- Sensor to spot check blood levels
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Nonin Medical, Inc
Acute Brain Injury
Transcutaneous Pulse Oximetry Brain Monitoring Study (US)
This is a study of adult patients with a severe and sudden brain injury who have a drain placed in their brain to measure pressure.
- Trial name
- T-POT US (NCT06267131)
- Testing
- Brain Pulse Oximeter
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cyban Pty Ltd
Cardiac Output, High, Cardiac Output, Low
Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone
The purpose of this study is to compare changes of minimally invasive arterial pulse contour cardiac output with changes of intermittent and continuous thermodilution cardiac output by pulmonary artery catheter in hemodynamic…
- Conditions
- Cardiac Output, High, Cardiac Output, Low, Vasodilation, Vasoconstriction
- Trial name
- NCT00583687
- Testing
- Vigileo TM / Flotrac TM (Minimally invasive cardiac output system consisting of arterial line sensor and cardiac output monitor), Passive leg raising, Volume challenge / Change of vasoactive drugs or inotropics
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pregnancy
Fetal Pulse Oximetry Trial (FOX)
The purpose of this study is to determine if the information provided to the physician by a fetal pulse oximeter during labor will reduce the chances of a cesarean delivery.
- Trial name
- NCT00098709
- Testing
- Fetal pulse oximeter
- Where
- 13 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
SpO2 (Peripheral Oxygen Saturation) Measurement Validation
Philps FAST2022 picoSAT Pulse Oximetry Desaturation Study
Validation study to compare the accuracy of non-invasive Philips SpO2 sensors in detecting blood oxygen levels compared to invasive methods requiring a blood draw and lab analysis.
- Trial name
- NCT05683366
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Healthy Vollunteer, Apnea
Temporal Dynamics of Peripheral SpO₂ During Reoxygenation
Pulse oximeters estimate arterial oxyhaemoglobin saturation (SaO₂) from photoplethysmographic signals recorded at peripheral sites (usually the fingertip), thus measuring the peripheral oxygen saturation (SpO₂).
- Trial name
- PulseOx (NCT07884500)
- Testing
- Voluntary Apnea
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Premature Birth
Neonatal Pulse Oximetry Sensor Study
To validate the SpO2 accuracy, bias, and precision of Medline's reprocessed pulse oximetry sensors as compared to SaO2 in arterial blood samples as assessed by CO-oximetry in neonates.
- Trial name
- NCT05250102
- Testing
- Pulse oximeter sensors
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Medline Industries
Anesthesia
Correlation of Non Invasive Hemoglobin Measurement With Laboratory Hemoglobin Measurement in Living Liver Donors
Pulse CO-Oximetry (Masimo Corp, Irvine, CA, USA) is a method that allows non-invasive continuous hemoglobin (Hb) measurement. This technology measures continuous Hb with a multi-wavelength spectrophotometric fingertip sensor.
- Trial name
- NCT04664777
- Testing
- Masimo Model RDS7A
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Inonu University
Arterial Disease
Vital USA SpO2 Accuracy Comparison to Arterial Blood CO-Oximetry
Clinical Investigation Plan: Vital USA SpO2 Accuracy Comparison to Arterial Blood CO-Oximetry Study ID# PR 2019-353, Version: Rev 1, Date: 15 Oct 2019 Study Dates: November 4-5, 2019
- Trial name
- NCT04285411
- Testing
- Accuracy of the VitalDetect™ pulse oximetry system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vital USA, Inc.
Post Surgical Respiratory Failure, Respiratory Complication
Advanced Prediction of Respiratory Depression Episode With the Linshom Continuous Predictive Respiratory Sensor
Investigators will enroll 320 patients who will undergo non-cardiac surgery, receive supplemental oxygen via face mask, and will be on a continuous pulse oximetry monitor in the Post Anesthesia Care Unit (PACU).
- Trial name
- NCT05804175
- Testing
- Linshom Continuous Predictive Respiratory Monitoring
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- Linshom Medical, Inc.
Pulse Oximetry
SpO2 Verification Study - Philips Nasal Alar With Nellcor OxiMax SpO2 Board (453564624031)
The primary purpose of the clinical investigation is to verify the SpO2 accuracy of the Philips AlarX5 SpO2 sensor with Nellcor OxiMax SpO2 Board.
- Trial name
- NCT07680530
- Testing
- Evaluation of Oxygen Sensors
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Carbon Monoxide Poisoning
Dysfunctional Hemoglobin Pulse Oximetry
The purpose of the study is to assess device performance in the presence of carbon monoxide.
- Trial name
- NCT03030833
- Testing
- Pulse Oximeter
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Nonin Medical, Inc
Hypoxemia
Pulse Oximetry With Automated Verbal Prompts
This study will evaluate the effectiveness of an automated voice prompting system on post operative hypoxia within the Postoperative Anesthesia Care Unit (PACU).
- Trial name
- NCT02930863
- Testing
- pulse oximetry software, Brief post-PACU stay survey.
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Florida
Respiratory Failure, Hypoxemia
Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study
The oximeter is used to monitor intensive care patients undergoing oxygen therapy. It indicates pulsed oxygen saturation (SpO2), a reflection of arterial oxygen saturation (SaO2) which enables detection of hypoxemia and…
- Conditions
- Respiratory Failure, Hypoxemia, Hyperoxemia
- Trial name
- Oxygap 2 (NCT06102499)
- Testing
- SpO2 and SaO2 comparison
- Where
- 3 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Laval University
Oximetry
Accuracy of Pulse Oximeters With Profound Hypoxia
To test the accuracy of a non-invasive blood oxygen saturation monitor which is placed on a subject with profound hypoxia.
- Trial name
- NCT04324385
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Compumedics Limited
Oxygen Saturation, Respiratory Distress Syndrome
Imputation of Arterial Oxygen Partial Pressures Using Pulse Oximetry
This study aims to validate existing PaO₂ prediction equations (Rice, Pandharipande, Gadrey, Hill, Severinghaus-Ellis) by comparing predicted PaO₂ values with measured values.
- Conditions
- Oxygen Saturation, Respiratory Distress Syndrome, Anesthesia, General
- Trial name
- NCT06283914
- Where
- Lebanon
- Volunteers
- 300 people
- Sponsor
- American University of Beirut Medical Center
Apnea, Circulatory; Change
Plethysmography Curve Variability Depending on the Breath Cycle
The aim of the study is to analyze the variability of plethysmography curve depending on the breath cycle (respiratory rate and tidal volume).
- Conditions
- Apnea, Circulatory; Change, Respiration
- Trial name
- NCT05302219
- Testing
- Respiratory rate, Tidal volume, Apnea
- Where
- Czechia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Czech Technical University in Prague
Critically Ill Black Patients
Usefulness of Non-invasive Pulse Co-oximetry Haemaglobin Measurements in Critically Ill Black Patients
To answer the question whether a non-invasive haemaglobin measurement is clinically useful, reliable and accurate as compared to taking a blood sample and checking the haemaglobin level at the laboratory or in a blood gas…
- Trial name
- NCT02035306
- Testing
- non invasive co-oximetry haemaglobin measurement
- Where
- South Africa
- Volunteers
- 149 people
- Sponsor
- Chris Hani Baragwanath Academic Hospital