Clinical trials: Packed Red Blood Cells
Anemia, Critical Illness
Effect of Packed Red Blood Cell Transfusion on Eicosanoid Profiles in Plasma of Intensive Care Patients
The main goal of this pilot study is to assess the time course of eicosanoid profiles in intensive care unit (ICU) patients requiring packed red blood cell (PRBC) transfusion.
- Conditions
- Anemia, Critical Illness, Lung Transplantation, Open Aortic Surgery
- Trial name
- EICOTRANS-p (NCT03782623)
- Testing
- Analysis of eicosanoid profile prior to and after PRBC transfusion
- Where
- Austria
- Volunteers
- 23 people
- Sponsor
- Medical University of Vienna
Necrotizing Enterocolitis
The Impact of Different Feeding Strategies During Packed Red Cell Transfusion on Intestinal Oxygenation
This study aims to compare the differences between three different feeding regimens on intestinal oxygenation during packed red blood cell (PRBC) transfusion in premature babies.
- Trial name
- NCT02733718
- Testing
- NIRS (near-infrared spectroscopy)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Packed Red Cells Causing Adverse Effects in Therapeutic Use
Investigating Microparticle Levels In Filtered Packed Red Blood Cell Units
Red blood cell (RBC) transfusion is a common therapeutic approach, and almost 85 million packed red blood cells (pRBCs) are transfused annually worldwide.Transfusion efficacy largely depends on the patient's general health, but…
- Trial name
- NCT06428747
- Testing
- b. Detection of micro particles and their subtypes by flow cytometery on(BECKMAN COULTER CytoFLEX flow cytometer).
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Necrotizing Enterocolitis of Newborn, Feeding Intolerance
Impact of Enteral Feeding on Splanchnic Oxygenation During Packed Red Blood Cell Transfusion in Preterm Infants
This clinical trial aims to learn if enteral feeding influences cerebral and splanchnic oxygenation during red blood cell infusion in very low birth-weight preterm infants.
- Conditions
- Necrotizing Enterocolitis of Newborn, Feeding Intolerance, PreTerm Neonate, Transfusion Related Complications
- Trial name
- TANEC (NCT06632314)
- Testing
- Enteral feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Akdeniz University
Anemia of Prematurity
The Effect of Blood Transfusion on Blood Flow to the Intestines of Premature Infants
The purpose of the study is to see if a blood transfusion changes how fast blood flows to the intestines of a premature baby. Blood flow is measured by an ultrasound test.
- Trial name
- NCT00167388
- Testing
- feed during blood transfusion
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
PRBC Transfusion, CABGs
Packed Red Blood Cell Transfusion in Elective Coronary Artery Bypass Graft Surgery in A University Hospital
In Siriraj Hospital, blood consumption in Cardiac surgery is high (units per patient) and frequent (number of patients receiving blood).
- Trial name
- NCT02585310
- Testing
- Packed red blood cell transfusion
- Volunteers
- 300 people
- Sponsor
- Mahidol University
Transfusions
Impact of Feeding on Pro-Inflammatory Cytokine Response in Neonates Receiving a RBC Transfusion
Prior to a non-urgent blood transfusion, subjects will be randomized to either stopping feeds or continuing feeds. The intervention group will be the placement of a subject in the NPO group.
- Trial name
- NCT01949896
- Testing
- NPO, Control group: continue feedings
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Preterm Newborns
Inflammation and Cerebral Oxygenation in Preterm Newborns Following Fetal Red Blood Cell Transfusion Compared to Adult Red Blood Cell Transfusion
Among diseases associated with premature birth, retinopathy of prematurity (ROP) is one of the most important causes of childhood blindness. ROP develops in the immature retina as a consequence of prolonged exposure to hyperoxia.
- Trial name
- INCONTRA (NCT06851390)
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Hemostasis, Surgical
The Safety and Effectiveness of PROCRIT (Epoetin Alfa) in Patients Undergoing Elective Major Abdominal and/or Pelvic Surgery
The primary purpose of the study is to compare the effect of perioperative (the time period describing the duration of a participants surgical procedure) administration of PROCRIT to that of Standard of Care (SOC) on the…
- Trial name
- NCT00350519
- Testing
- Epoetin alfa, Standard of Care
- Volunteers
- 37 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
The Focus is on the Detection of the Consequences of Autologous Blood Transfusion in Healthy Volunteers
Biological Parameters Changes After Autologous Blood Transfusion of Red Blood Cells (200 ml) in Healthy Volunteers.
The purpose of this study is to evaluate if differences between samples of subjects obtained before autologous blood transfusion or samples of non-transfused subjects and samples of subjects after autologous blood transfusion can…
- Trial name
- AUTOT-SPORT (NCT03889834)
- Testing
- Autologous Blood Transfusion, No transfusion
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Iron, Abnormal Blood Level
PICU Transfusion Study: Harmful Effects of Red Blood Cell Transfusions
The investigators hypothesize that the storage-damaged red cells are responsible for some of the adverse effects of transfusion.
- Trial name
- NCT02087553
- Testing
- Transfusion of red blood cells, Infusion of albumin/saline
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Columbia University
Anemia
The Impact of Red Packed Cells Transfusion on the Main Biological Markers to Determine the Etiology of Anemias
The aim of this work is to study the changes of key assays useful for the understanding of anemia mechanism before and after red packed cells transfusion: iron status, vitamin assays, hemolysis markers.
- Trial name
- BÉA/T (NCT01409967)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Melanoma, Sarcoma
A Randomized Controlled Study Comparing Priming Solution Containing Crystalloid or Packed Red Blood Cells in Patients Treated With Isolated Limb Perfusion.
The primary aim of this study is to investigate the possibility to replace an erythrocyte based prime solution with a crystalloid based prime solution while maintaining metabolic function.
- Trial name
- ILP-Prime (NCT03073304)
- Testing
- Crystalloid based prime solution, Erythrocyte based prime solution
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Vastra Gotaland Region
Iron, Abnormal Blood Level, Other Abnormal Blood Chemistry
Fresh Versus Old Red Blood Cells for Transfusion
Packed red blood cell units destined for transfusion can be stored for up to 42 days prior to transfusion based on Food and Drug Administration (FDA) guidelines.
- Trial name
- NCT01319552
- Testing
- Fresh transfusion, Old transfusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anemia
The Safety and Effectiveness of Jobelyn in Pre-operative Management of Anaemia in Gynaecological Patients
PROTOCOL FOR THE STUDY OF THE SAFETY AND EFFICACY OF JOBELYN, IN THE PREOPERATIVE MANAGEMENT OF ANAEMIA IN GYNAECOLOGICAL PATIENTS
- Trial name
- NCT01670955
- Testing
- Jobelyn, Ferrous Sulphate + Folic Acid
- Where
- Nigeria
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Lagos State University