Clinical trials: Paediatric Patients
Cardiac Dysfunction
Cardiac Arrhythmias and Dysfunction in the Pediatric Burn Patient
The purpose of this study is to collect information about how often an abnormal heart beat happens in children who have been burned.
- Trial name
- NCT03085420
- Testing
- Echocardiogram
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shriners Hospitals for Children
Cardiotoxicity
Remote Ischaemic Preconditioning in Childhood Cancer
Survival rates of children with cancers have improved significantly in the recent few decades. Nonetheless, the side effect of this class of drugs on heart function remains to be an issue of concern.
- Trial name
- NCT03166813
- Testing
- Remote Ischaemic Preconditioning, Control
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- The University of Hong Kong
Infection, Human Immunodeficiency Virus I
48-Week Study Of GW433908 And Ritonavir Or GW433908 Alone, Twice Daily In Pediatric Patients With HIV Infection
This is a 48-week study to collect information on the safety and activity of an investigational medicine in patients, ages 2 to 18 years old, with HIV infection .
- Trial name
- NCT00089583
- Testing
- LEXIVA (GW433908), Ritonavir
- Where
- 39 sites in United States, Belgium and 5 more
- Volunteers
- 110 people
- Sponsor
- ViiV Healthcare
Postoperative Pain, Postoperative Nausea
Outcomes of Carbohydrate Loading Paediatric Patients Preoperatively for Tonsillectomy and Adenoidectomy
Randomised control trial of 150 paediatric patients aged between 3-8years. One group will receive a preoperative carbohydrate oral drink and the other group will receive current standard care (no drink) prior to undergoing…
- Conditions
- Postoperative Pain, Postoperative Nausea, Satisfaction, Sleep
- Trial name
- NCT03639012
- Testing
- Carbohydrate drink
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jessica Gray
Verruca Vulgaris, Molluscum Contagiosum Skin Infection
Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca
This study is going to test a cold atmospheric plasma device (CAP), in particular a floating electrode-dielectric barrier device (FE-DBD), to treat warts and molluscum.
- Trial name
- NCT05070754
- Testing
- Floating electrode-dielectric barrier device (FE-DBD) cold atmospheric plasma (CAP), Cryotherapy, Canthardin Collodion
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Medical University of South Carolina
Children, Adolescent
How Digital Media Affects Kids' Healthcare Experiences and Outcomes
The goal of this clinical trial is to learn whether different forms of media (2D, 360, or 360 in virtual reality) have different impacts on pre-procedural anxiety and post-procedural pain in children.
- Conditions
- Children, Adolescent, Anxiety, Pain
- Trial name
- NCT07073027
- Testing
- 2D video on smartphone, 360 video on smartphone, 360 video on smartphone inserted into VR cardboard headset
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Type 1 Diabetes
Threshold Suspend in Pediatrics at Home
The study objective is to demonstrate that home use of Threshold Suspend (TS) is not associated with glycemic deterioration in pediatric patients with type 1 diabetes, as measured by change in A1C.
- Trial name
- NCT02120794
- Testing
- 530G Insulin pump
- Where
- 16 sites in United States
- Volunteers
- 194 people
- Sponsor
- Medtronic MiniMed, Inc.
Sepsis
Smart Discharges for Older Children
This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are…
- Trial name
- NCT07629154
- Testing
- No Intervention: Observational Cohort
- Where
- 7 sites in United States, Canada and 3 more
- Volunteers
- 4,000 people
- Sponsor
- University of British Columbia
Anatomic Abnormality, Internal Jugular Vein
Ultrasound Measurement of RIJV in Patients Between 0-2 Years
After obtaining parental consent ultrasonographic evaluation of right internal jugular vein will be performed in pediatric patients undergoing elective surgeries between 0-2 years of age.
- Conditions
- Anatomic Abnormality, Internal Jugular Vein, Neonates, Infants, Premature
- Trial name
- NCT03604094
- Testing
- Ultrasonographic evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
COVID-19
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after you take it), and efficacy (how well a study…
- Trial name
- NCT05261139
- Testing
- nirmatrelvir, ritonavir
- Where
- 73 sites in United States, Bulgaria and 5 more
- Volunteers
- 160 people
- Sponsor
- Pfizer
Hyperphosphatemia
A Study to Investigate the Safety and Efficacy of PA21 (Velphoro®) and Calcium Acetate (Phoslyra®) in Paediatric and Adolescent Chronic Kidney Disease (CKD) Patients With Hyperphosphataemia
This is a Phase 3, Open-label, Randomised, Active-controlled, Parallel Group, Multicentre Study to Investigate the Safety and Efficacy of PA21 (Velphoro®) and Calcium Acetate (Phoslyra®) in Paediatric and Adolescent CKD Patients…
- Trial name
- NCT02688764
- Testing
- PA21 (Velphoro®), Calcium Acetate (Phoslyra®)
- Where
- 38 sites in United States, France and 5 more
- Volunteers
- 85 people
- Sponsor
- Vifor Fresenius Medical Care Renal Pharma
Psychiatric Disorder
Pilot Study of the Vermont Family Based Approach in Primary Care Pediatrics
This pilot randomized controlled trial of the Vermont Family Based Approach (VFBA) tested the feasibility of the VFBA in primary care pediatrics and its effects on children's and parents' emotional and behavioral problems and…
- Trial name
- NCT04412590
- Testing
- Vermont Family Based Approach, Treatment as Usual
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Apophysitis; Juvenile
Iontophoresis With Dexamethasone and Physical Therapy to Treat Apophysitis of the Knee in Pediatrics
The goal of this clinical research study is to determine if there is a difference in time to meet return to sport criteria for Pediatric patients with apophysitis of the knee who receive iontophoresis with Dexamethasone Sodium…
- Trial name
- NCT03606980
- Testing
- Dexamethasone Sodium Phosphate, Iontophoresis, Physical Therapy
- Where
- 5 sites in United States
- Volunteers
- 45 people
- Sponsor
- Children's Health System, Inc.
Paediatrics, General Anaesthesia
Comparison of the Anaesthetic Gases in Maintainance of General Anaesthesia in Paediatrics
Desflurane and Sevoflurane are one of the modern inhalational anaesthetic agents currently in use in anaesthetic practice. The properties of desflurane that has low blood gas solubility coefficient of 0.47 compared to sevoflurane…
- Trial name
- NCT04771962
- Testing
- DESFLURANE AND SEVOFLURANE
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Ambulatory Children With Single Ventricle
NIRS Monitoring in the Ambulatory Single Ventricle Patient
The normal heart has four chambers. There are two upper (or filling) chambers and are called the atrium. There are two lower (or pumping) chambers and are called the ventricles.
- Trial name
- NCT00166218
- Testing
- near-infrared spectroscopy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Telemedicine, Pediatrics
Improving Nighttime Access to Care and Treatment; Part 4-Haiti
Children in resource-limited settings who develop illness at night are often isolated from care, resulting in progression to an emergency.
- Trial name
- INACT4-H (NCT05480930)
- Testing
- paper-based clinical decision support (dCDS) tool, digital clinical decision support (dCDS) tool
- Where
- Haiti
- Volunteers
- 7,124 people
- Sponsor
- University of Florida
Social Needs, Health-Related Social Needs
The Social Needs Assistance for Hospitalized Kids Trial
The goal of this clinical trial is to determine the best way to help families access social and economic support services in order to improve children's health for hospitalized children and their families/caregivers.
- Conditions
- Social Needs, Health-Related Social Needs, Social Determinants of Health (SDOH), Social Needs Status
- Trial name
- SNAK (NCT07687238)
- Testing
- Active Assistance by Navigators, Passive Referral
- Where
- 6 sites in United States
- Volunteers
- 1,880 people
- Sponsor
- University of California, San Francisco
Surgery
Non-Interventional (Observational) Post-Authorization Safety Study of HES 130/0.42 in Paediatric Patients
This observational (non-interventional) post-authorization safety study (PASS) will investigate the application of Venofundin 6% and of Tetraspan 6% in children with special regard to drug safety.
- Trial name
- NCT00806533
- Testing
- HES 130 / 0.42 (Venofundin 6%, Tetraspan 6%)
- Where
- 10 sites in Austria, Czechia and 3 more
- Volunteers
- 1,130 people
- Sponsor
- B. Braun Melsungen AG
Prader-Willi Syndrome
Effects of Exenatide on Overweight Adolescents With Prader-Willi Syndrome
Prader-Willi Syndrome (PWS) is one of the most common genetic causes of obesity. Obesity is a major source of morbidity and mortality in this population.
- Trial name
- NCT01444898
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Los Angeles
Pediatric Critical Illness
Indirect Calorimetry Measurement in the Pediatric Intensive Care Unit's Smallest Patients
Indirect calorimetry is considered the reference method for measuring energy expenditure in intensive care patients. However, in infants and small children weighing less than 10 kilograms, its clinical use has historically been…
- Trial name
- Q-NRG2025 (NCT07462806)
- Testing
- Q-NRG+
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet