Clinical trials: Pain, Labor
Pregnancy, Labor Pain
Epidural Volume Extension During a Combined Spinal-Epidural Technique for Labor Analgesia.
Combined spinal-epidurals (CSE) involve the injection of pain relief medication into the cerebral spinal fluid (CSF) and the insertion of an epidural catheter in the epidural space to continue to give pain relief medication.
- Trial name
- NCT01810406
- Testing
- CSE with 10 ml EVE, CSE without EVE
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- IWK Health Centre
Chronic Physical Health Conditions
MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace
The specific aim of the study is to evaluate the health benefits of a series of group workshops designed for workers with chronic physical health conditions.
- Trial name
- NCT01978392
- Testing
- Self-management group workshops
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Labor Pain
Effectiveness of Using the Swiss Ball in Birth
A randomized clinical trial will be conducted to evaluate the effectiveness of using the Swiss Ball as a resource that reduces the length of labor time.
- Trial name
- BIRTHBALL (NCT04124835)
- Testing
- Swiss Ball, Control Grup
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Therapeutic Touch, Childbirth
Effect of Therapeutic Touch on Labor Pain and Hormone Levels
This study was conducted to determine the effect of sacral region-focused therapeutic touch applied during the latent phase of labour on hormone levels, labour comfort, and perception.
- Trial name
- NCT05179915
- Testing
- Therapeutic Touch focused on sacral region
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Labor Pain, Labor Duration
Effects of the Rebozo Technique During Active Labor on Labor Pain and Labor Duration in Primiparous Women
Study Description Childbirth is a physiological process often accompanied by severe pain and prolonged labor, which may negatively affect maternal well-being and increase the likelihood of obstetric interventions.
- Conditions
- Labor Pain, Labor Duration, Childbirth, Management of Delivery
- Trial name
- Rebozo Techniq (NCT07759479)
- Testing
- Rebozo technique, Routine Intrapartum care
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Bronchopulmonary Dysplasia
Hydrotherapy in Premature Infants With Bronchopulmonary Dysplasia
Premature newborns (PTNB) often develop bronchopulmonary dysplasia (BPD) which can be related to an inability to maintain differences in tonus patterns (extensor and flexor) between the cervical muscles, upper and lower limbs.
- Trial name
- NCT03538977
- Testing
- Hydrotherapy, Conventional Physiotherapy
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Estadual de Londrina
Labor Pain
Programmed Intermittent Epidural Bolus for Labor Analgesia During First Stage of Labor
Until recently, at Mount Sinai Hospital, epidural analgesia for labor pain was delivered with a pump that could only provide continuous infusion of the freezing medication in combination of pushes of medication activated by the…
- Trial name
- NCT02550262
- Testing
- Bupivacaine, Fentanyl, Infusion pump
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain
Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40
Placement of labor epidurals is a very common daily practice in obstetrical anesthesia. Currently, these epidurals are placed based upon palpation of landmarks to determine midline and the correct spinal level for placement.
- Trial name
- NCT02984267
- Testing
- Ultrasound, Palpation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Thomas J. Vernon
Labor Analgesia, Labor Pain
Effect of Dural Puncture Epidural Analgesia on Oxytocin in Early vs Late Labor
Oxytocin is a key hormone that regulates uterine contractions during labor. Dural Puncture Epidural Analgesia (DPEA) is a modern technique for labor pain relief that provides faster onset and more reliable analgesia than standard…
- Conditions
- Labor Analgesia, Labor Pain, Oxytocin
- Trial name
- DPEA-OXY (NCT07873814)
- Testing
- Dural Puncture Epidural Analgesia (DPEA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Labor Pain
Pain Relief Effects on Length of Labor
This study divides patients into two groups when they ask for medicine to help relieve the pain of contractions. One group will be selected to receive an epidural and another group will be selected to receive both a spinal dose…
- Trial name
- NCT01750099
- Testing
- Combined Spinal-epidural, Continuous Lumbar epidural
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- University of Texas Southwestern Medical Center
Anxiety, Labor Pain
Effectiveness of a Virtual Reality Intervention on Pain, Anxiety, and Satisfaction in Laboring Women
This study is designed to evaluate whether a virtual reality (VR) intervention can help reduce pain and anxiety and improve childbirth satisfaction among laboring women.
- Trial name
- NCT07329764
- Testing
- Virtual Reality
- Where
- Taiwan
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Wan-Lin Pan
Labor Pain, Dural Puncture Epidural Technique
Two Different Sized Spinal Needles DPE vs Conventional Epidural Technique
DPEA (Dural Puncture Epidural Analgesia) is an alternative to the conventional epidural analgesia and technically a Combined Spinal Epidural (CSE) with omission of intrathecal drugs administration.
- Trial name
- NCT07708909
- Testing
- Dural Puncture Epidural Analgesia 27G, Dural Puncture Epidural Analgesia 25G, Conventional epidural
- Volunteers
- 240 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Patent Ductus Arteriosus, Prematurity
Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
The primary objective is to evaluate the Patent Ductus Arteriosus (PDA) closure rate of early vs. late use of Ibuprofen (Ibu). The investigators believe that early use of Ibu will have a higher PDA closure rate than later use of…
- Trial name
- NCT00833365
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Retinopathy of Prematurity
Pain Response During Examination for Retinopathy of Prematurity
Newborns infants equal or less than 1500 grams and/or equal and less than 32 weeks will have ophthalmologic examination for ROP at 6 weeks old.
- Trial name
- ROP (NCT00648687)
- Testing
- suck 12.5% dextrose in water 5 minutes before the procedure
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- National Bioethics Commission of Brazil
Labor Pain, Posttraumatic Growth
The Effect of Massage and Musıc Therapy on Birth Pain, Posttravmatic Comfort and Posttraumatic Development
Birth pain is the most severe painful experience faced by primiparous people. Massage and music therapy reduce tension in the muscles and reduce the feeling of pain. Massage and music therapy will be applied to pregnant women.
- Trial name
- NCT05317052
- Testing
- Massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Amasya University
Labor Pain
Management of Postoperative Pain With Preemptive Analgesia in Cesarean Section
This research will explore the question of whether preincisional skin infiltration with bupivacaine 0.25% decreases postoperative pain after Cesarean delivery.
- Trial name
- NCT02879435
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mark Kosanovich
Labor Pain
Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Epidural analgesia has proven to be an effective method for severe pain relief associated with labor and delivery. During labor, a low dose continuous infusion of local anesthetic and narcotic will be administered through an…
- Trial name
- NCT01846221
- Testing
- Clonidine, Fentanyl
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Columbia University
Orthopedic Disorder, Thoracic
Epidemiological Data on Pain
The ALGOBASES project is an observational epidemiological study of pain through the collection of pain evaluation questionnaires and information with the aim of creating a descriptive "pain" evaluation in all patients who need to…
- Conditions
- Orthopedic Disorder, Thoracic, Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus, Pain
- Trial name
- ALGOBASES (NCT04546594)
- Sponsor
- University Hospital, Lille
Transcutaneous Electric Nerve Stimulation, Labor Pain
Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) Versus Placebo During the First Stage of Labor
This study seeks to verify the analgesic efficacy of TENS during the first stage of labor applying TENS parameters that, according to with the evidence, can be effective for this application and discarding the placebo effect…
- Trial name
- NCT03990441
- Testing
- TENS
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Labor Pain
Transcutaneous Electrical Nerve Stimulation for Labor Pain Control in Combination With Cardiotocography
Transcutaneous electrical nerve stimulation (TENS) is a non-invasive electro-physical modality used for several pain conditions including labor pain control.
- Trial name
- NCT04946838
- Testing
- DS5 electrical stimulator
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Aalborg University