Clinical trials: Pain, Medication
Chronic Neck Pain, Chronic Low Back Pain
Group Acupuncture Therapy With Modified Yoga
Chronic pain is prevalent in the U.S., with impact on physical and psychological functioning as well as lost work productivity. Minority and lower socioeconomic populations have increased prevalence of chronic pain with less…
- Conditions
- Chronic Neck Pain, Chronic Low Back Pain, Osteoarthritis Pain
- Trial name
- GAPYOGA (NCT04296344)
- Testing
- Acupuncture Therapy Treatments, Yoga Therapy Sessions
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ankyloglossia
Analgesic Effect of Inhaled Lavender Essential Oil for Clipping of Tongue-ties
Clipping of the tongue-tie is a common procedure that neonatologists perform in our neonatal unit to help establish breastfeeding.
- Trial name
- LEO-SME1 (NCT04877392)
- Testing
- Lavender essential oil
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Parc de Salut Mar
Orthodontic Pain (D013850), Pain Management (D016146)
A Randomized Clinical Trial of the Effectiveness of Acupressure in Relieving Orthodontic Pain
Orthodontic treatment with fixed appliances often causes pain, which peaks within 24 hours after archwire placement and lasts for several days.
- Conditions
- Orthodontic Pain (D013850), Pain Management (D016146), Acupressure (D056351), Analgesics, Non-Narcotic (D000700)
- Trial name
- NCT06812936
- Testing
- Acetaminophen, Acupressure
- Where
- Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Pain
Analgesic Treatment for Cancer Pain in South East Asia
This study is planned to investigate the pain control status in cancer patients in 6 South East Asian countries through evaluation of prescription pattern of analgesics, satisfaction of pain control, quality of life and…
- Trial name
- ACE (NCT02664987)
- Testing
- Patients receiving cancer pain treatment
- Volunteers
- 462 people
- Sponsor
- Mundipharma Pte Ltd.
Central Pain Syndrome
Comparison of rTMS and H Coil in Neuropathic Pain
rTMS of the motor cortex is an increasingly established analgesic technique for the treatment of neuropathic pain. However its efficacy is generally modest.
- Trial name
- HNEP (NCT03370107)
- Testing
- rTMS
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Hospital Ambroise Paré Paris
Patients Receiving Hepatectomy Under General Anesthesia
Analgesic Effect of Intrathecal Morphine Combined With Low Dose Local Anesthetics on Postoperative Analgesia After Liver Resection
Efficient postoperative pain control plays a vital part in the management of patients after surgery. In particular, major surgeries including hepatectomy cause intense postoperative pain that may result in cardiovascular or…
- Trial name
- NCT05208801
- Testing
- Percutaneous injection, Morphine, Morphine+Bupivacaine
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Spinal Anesthesia Evaluation, Analgesic
Effect of Different Doses Of Intrathecal Dexmedetomidine In Combination With Bupivacaine On Spinal Anesthesia
This study is designed to assess the efficacy of different doses of dexmedetomidine in combination with intrathecal hyperbaric bupivacaine on spinal anesthesia and its postoperative analgesic characteristics on patients…
- Conditions
- Spinal Anesthesia Evaluation, Analgesic, Intrathecal Anesthesia
- Trial name
- NCT07051512
- Testing
- dexmedetomidine 4μg, dexmedetomidine 8 μg, dexmedetomidine 10 μg
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Analgesic Efficacy
Suzetrigine Frame Trial Comparing Suzetrigine and Acetaminophen
Local anesthetic infiltration is a primary source of acute pain during stereotactic procedures.
- Trial name
- NCT07525219
- Testing
- Suzetrigine, acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Post Cesarean Pain Management
To Compare the Efficacy and Patients' Satisfaction for the Treatment of Post Cesarean Pain of Two Protocols: Oral Medications in Fixed Time Interval Administration Versus Spinal Morphine
Cesarean deliveries are prevalent. Unlike other operations, quick recovery is required for the mother to nurture the newborn child and establishing an appropriate mother-child bonding.
- Trial name
- NCT02440399
- Testing
- Tramadol hydrochloride, Morphine, Paracetamol
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- HaEmek Medical Center, Israel
Stable Angina Pectoris, Unstable Angina Pectoris
PCB for Long De Novo Lesions of Main Coronary Arteries (D-Lesion Long Trial)
This study evaluates the Efficacy and Safety of Paclitaxel-Coated Balloon Catheter in Patients With Diffuse Long De Novo Lesions of Main Coronary Arteries.
- Trial name
- NCT03155971
- Testing
- Paclitaxel-Coated Balloon
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The People's Hospital of Liaoning Province
Migraine, Headache
Comparing the Safety and Effectiveness of Topiramate With the Safety and Effectiveness of Amitriptyline in Preventing Migraine Headaches
The purpose of this study is to compare the effectiveness and safety of two treatment regimens in preventing migraines. The antidepressant amitriptyline has been used successfully to prevent migraine headaches.
- Trial name
- NCT00210821
- Testing
- topiramate
- Volunteers
- 347 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Femur Fracture
Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?
The purpose of this study is to monitor severe pain for femur fracture after treatment with paracetamol IV or OR.
- Trial name
- NCT05025228
- Testing
- Paracetamol
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Spondylolisthesis, Facet Joint Hypertrophy
Caudal Block Versus Quadratus Lumborum Plane Block in Lumbar Surgery
Postoperative pain is a common complication after lumbar spine surgery due to inherent tissue damage during surgical procedures. Many analgesic options have been explored.
- Conditions
- Spondylolisthesis, Facet Joint Hypertrophy, Spinal Canal Stenosis
- Trial name
- NCT06398600
- Testing
- Caudal, Quadratus lumborum plane block
- Where
- Egypt
- Volunteers
- 111 people
- Sponsor
- Fayoum University Hospital
Congenital Muscular Torticollis
Ultrasound Guided Intermediate Cervical Plexus Block for Congenital Muscular Torticollis
Congenital Muscular Torticollis (CMT) is a postural deformity of head and neck detected at birth or shortly after birth, primarily resulting from unilateral shortening of Sternocleidomastoid Muscle (SCM).
- Trial name
- NCT02651311
- Testing
- intermediate cervical plexus block, Fentanyl, Ibuprofen
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Ajou University School of Medicine
Analgesia; Postoperative
Effect of Single Dose Intravenous Magnesium Sulfate on Postoperative Analgesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy
This study describes a randomized controlled trial designed to evaluate the impact of a single intravenous dose of magnesium sulfate on postoperative analgesic consumption in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07328893
- Testing
- Magnesium Sulfate 30 mg/kg intravenous diluted in 100 ml Normal Saline.
- Where
- 2 sites in India
- Volunteers
- 106 people
- Sponsor
- Tata Main Hospital
Pain, Postoperative
A Multicentre, Double-Blind, Double-Dummy, Randomised Study of the Analgesic Efficacy and Safety of Valdecoxib Compared to Diclofenac Sodium in Patients Undergoing Knee Arthroscopy for Anterior Cruciate Ligament (ACL) Reconstruction
To demonstrate non-inferiority of valdecoxib 20 mg twice daily (BID) (with an initial loading dose of 40 mg followed by a second dose of 20 mg on the first day only) with diclofenac sodium delayed release 75 mg BID in analgesic…
- Trial name
- NCT00650598
- Testing
- valdecoxib, diclofenac
- Where
- 25 sites in Australia, Hong Kong and 7 more
- Volunteers
- 328 people
- Sponsor
- Pfizer
Pain, Complications
Comparison of Two Kinds of Postoperative Analgesia After Amputation
Pain after amputation is a significant problem among amputees. Phantom limb pain may appear in up to 85% of patients and is usually resistant to a wide variety of treatments.It is believed that regional anesthesia, by preventing…
- Trial name
- NCT02114463
- Testing
- Local analgesic, Intravenous analgesic, ropivacaine
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Acute Pain
Analgesic Efficacy and Safety of ADL5859 in Subjects With Acute Dental Pain After Third Molar Extraction
The objective of this study is to evaluate the analgesic efficacy and safety of ADL5859 compared with placebo and an active control (ibuprofen) in subjects with acute dental pain after third molar extraction.
- Trial name
- NCT00993863
- Testing
- ADL5859 30 mg, ADL5859 100 mg, ADL5859 200 mg
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Hip Fractures, Methadone
Perioperative Methadone Compared to Placebo in Elderly Hip Fracture Patients
Hip fractures are associated with severe pain and are sustained by the elderly population. Demand for adequate pain relief combined with a low tolerance for analgesic drugs makes the treatment of elderly hip fracture patients…
- Trial name
- NCT06086171
- Testing
- Methadone Hydrochloride
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- University of Southern Denmark
Pancreatitis, Acute, Pain, Acute
Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children
The aim of the study is to assess the effectiveness and tolerance of pain treatment in AP in children using intravenous paracetamol in combination with ibuprofen or paracetamol in combination with metamizole.
- Conditions
- Pancreatitis, Acute, Pain, Acute, Pancreatic Disease, Pancreatic Diseases
- Trial name
- NCT07024199
- Testing
- The initial pain assessment, Drug administration according to protocol (paracetamol + ibuprofen OR paracetamol + metamizol), The effectiveness of the treatment
- Where
- Poland
- Volunteers
- 78 people
- Sponsor
- Medical University of Warsaw
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