Clinical trials: Pain, Medication
Opioid-Related Disorders, Pain, Acute
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of a New and a Marketed Tablet Formulation Under Fasted and Fed Conditions in Healthy Adults
This clinical trial is being conducted to compare concentrations of hydrocodone and acetaminophen in the blood after administration of a new and a marketed tablet formulation under fasted and fed conditions in healthy adults.
- Conditions
- Opioid-Related Disorders, Pain, Acute, Pain, Postoperative
- Trial name
- NCT03137017
- Testing
- Norco 5Mg-325Mg Tablet, GRT7014 - Abuse Deterrent Tablet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Gynecologic Disease
Ultrasound-guided Bilateral Rectus Sheath Block for Robotic Single-port Gynecologic Surgery
Rectus sheath block (RSB) is a kind of anterior abdominal wall block. It has postoperative analgesic effect for abdominal surgery with midline incision.
- Trial name
- NCT02450084
- Testing
- Rectus sheath block, Ropivacaine, Bandage
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Thoracic, Pain
Rhomboid Intercostal Sub Serratus Plane Block Versus Serratus Anterior Plane Block in Thoractomy
The objective of the current study is to compare the efficacy of the analgesic effect of ultrasound-guided unilateral Rhomboid intercostal and sub serratus plane block (RISS) versus Serratus anterior plane block (SAPB) in…
- Trial name
- NCT06856538
- Testing
- Bupivacain, Ultrasound
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yasser S Mostafa, MD
Castration-Resistant Prostatic Cancer
Pain Evaluation in Radium-223 Treated Castration Resistant Prostate Cancer Patients With Bone Metastases
This observational prospective single arm cohort study is designed to assess pain and bone pain related quality of life of metastatic Castration Resistant Prostate Cancer (mCRPC) patients receiving Radium-223 in a real life…
- Trial name
- PARABO (NCT02398526)
- Testing
- Radium-223 dichloride, (Xofigo, BAY88-8223)
- Where
- Germany
- Volunteers
- 363 people
- Sponsor
- Bayer
Infant, Newborn Diseases
Reduced Infant Response To A Routine Care Procedure After Glucose 25% Analgesia
Glucose has analgesic and calming effects in newborns. To date, it is not known whether the beneficial effects extend to care giving procedures that are performed after painful procedures.
- Trial name
- NCT01289808
- Testing
- Glucose 25%
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Heel Spur
A Comparison of the Analgesic Efficacies of Ultrasound and Shock Wave Therapy in the Patients With Calcaneal Spur
Heel spur is a troublesome disorder. Its formation is accompanied by pain in the area of heel and it makes walking limited or even impossible.
- Trial name
- NCT01510249
- Volunteers
- 3 people
- Sponsor
- Medical University of Lodz
Angina Pectoris
Comparison of Loading Strategies With Antiplatelet Drugs in Patients Undergoing Elective Coronary Intervention
Use of high loading doses of clopidogrel (antiplatelet drug) just before coronary interventions is associated with improved outcomes after coronary stenting.
- Trial name
- SASSICAIA (NCT02548611)
- Testing
- Prasugrel, Clopidogrel
- Where
- 5 sites in Germany, Hungary
- Volunteers
- 795 people
- Sponsor
- LMU Klinikum
Analgesics, Opioid, Anesthetics, Local
Opioid Use of Local Anaesthetic Agents in Open Heart Surgery and Its Effect on Recovery
The aim of this randomized controlled study was to investigate the effect of injecting local anesthetic agents into the sternotomy incision site and around the drains on the amount of opioids used in the postoperative period and…
- Trial name
- NCT06642077
- Testing
- LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Fibromyalgia, Pregabalin
The Efficacy and Safety of Pregabalin Combined With Toludesvenlafaxine in Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters.
- Conditions
- Fibromyalgia, Pregabalin, Duloxetine, Pain
- Trial name
- NCT07208357
- Testing
- Pregabalin, Pregabalin with toludesvenlafaxine
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Beijing Tiantan Hospital
Undesired Pregnancy
Comparing the Effectiveness of Oral Versus Intravenous Pain Medicine for Suction Curettage (D&C)
The main objective of this study is to determine the equivalency of oral conscious sedation and intravenous conscious sedation for first trimester surgical abortion.
- Trial name
- NCT00337792
- Testing
- oxycodone + lorazepam versus fentanyl + midazolam
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Congenital Muscular Torticollis
Ultrasound Guided Intermediate Cervical Plexus Block for Congenital Muscular Torticollis
Congenital Muscular Torticollis (CMT) is a postural deformity of head and neck detected at birth or shortly after birth, primarily resulting from unilateral shortening of Sternocleidomastoid Muscle (SCM).
- Trial name
- NCT02651311
- Testing
- intermediate cervical plexus block, Fentanyl, Ibuprofen
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Ajou University School of Medicine
Dental Pain
Maxi-Analgesic Phase 2 Study to Compare the Analgesic Effects in Different Dosing Groups to Treat Teeth Extraction Pain
The aim of the study is to examine the dose response relationship in the treatment of dental pain (teeth extraction) for the different potential doses of the investigational drug, i.e.
- Trial name
- NCT01104844
- Testing
- Full Dose Strength, Quarter dose strength, Half dose strength
- Where
- United States
- Sponsor
- AFT Pharmaceuticals, Ltd.
Acute Pain
IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
The goal of this randomized clinical trial is to compare the analgesic efficacy and side effect profile of IV acetaminophen as an analgesic adjunctive medication to IV hydromorphone for the treatment of acute pain experienced by…
- Trial name
- NCT03553498
- Testing
- IV acetaminophen, hydromorphone
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Albert Einstein College of Medicine
Anesthesia
Remifentanil on Hemodynamic Response to Anesthesia Induction
Effects of different doses of remifentanil on hemodynamic response to anesthesia induction in elderly patients ABSTRACT OBJECTİVE: The investigators compared the effects of three different doses of remifentanil infusion, which…
- Trial name
- NCT02763098
- Testing
- Remi 0.1, Remi 0.2, Remi 0.3
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Post Operative Analgesia, Tonsillectomy
Weight-Adjusted Diclofenac Potassium Medicated Lollipop for Post-Adenotonsillectomy Pain in Children
Brief Summary This study aimed to develop and conduct a preliminary clinical evaluation of a novel weight-adjusted gelatin-based diclofenac potassium medicated lollipop for the management of postoperative pain following…
- Conditions
- Post Operative Analgesia, Tonsillectomy, Pediatric Anesthesia
- Trial name
- DICLOPOP (NCT07646093)
- Testing
- Diclofenac Potassium Medicated Lollipop
- Where
- Venezuela
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Nerve Block, Video-Assisted Thoracic Surgery
Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) provides an opportunity to penetrate the thoracic cavity by video through an incision into the chest wall and facilitate surgical operation of lung pathologies.Various regional methods…
- Trial name
- NCT03483415
- Testing
- Morphine Sulfate, Bupivacaine
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pain
Laser Acupuncture for Pain Prevention in Neonates
Pain prevention and/or therapy in neonates is still a challenge. It is widely accepted that early pain experience can have a tremendous impact on the pain memory.
- Trial name
- NCT00528125
- Testing
- active laser acupuncture
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Children Hospital Homburg
Cardiac Surgery, Postoperative Pain
Erector Spinae Plane (ESP) Block With 20 ml Versus 30 ml in Cardiac Surgery
Even though erector spinae plane (ESP) block is shown to be efficient in cardiac surgery, it is still controversial how much volume is necessary for efficient analgesic effect for sternotomy and drain tube pain relief.
- Trial name
- NCT04928521
- Testing
- bilateral erector spinae plane block with 30 mL 0.25 % bupivacaine, bilateral erector spinae plane block with 20 mL 0.25 % bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Congestive Heart Failure, Angina Pectoris
Does Telephone Follow-up Improve Patients Satisfaction
Several studies have shown the importance of Telephone follow-up in reducing hospital readmissions for heart failure. Therefore, we aimed in this cohort to investigate whether telephone follow-up with patients discharged from the…
- Conditions
- Congestive Heart Failure, Angina Pectoris, Pneumonia, Urinary Tract Infection
- Trial name
- NCT00192738
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Rambam Health Care Campus
Medication Adherence
Study to Test the Efficacy of Online Education to Increase Safe Use of Opioid Medication.
The purpose of this project is to test whether an online pain medication intervention is a feasible and effective way to increase opioid pain medication safety.
- Trial name
- NCT01770314
- Testing
- Experimental
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Inflexxion, Inc.
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