Clinical trials: Pain, Medication
Fever, Analgesia
Paracetamol as Antipyretic and Analgesic Medication
The present study is aiming to unravel the clinical efficacy of intravenously administered paracetamol as antipyretic and analgesic medication in various medical conditions.
- Trial name
- APOTEL01 (NCT01070732)
- Testing
- Paracetamol
- Where
- 3 sites in Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Chronic Pain, Intractable Pain
Transitioning to a Valve -Gated Intrathecal Drug Delivery System (IDDS)
Flowonix Prometra® II Programmable Pump may require a smaller dose of drug when converting from other commercially available intrathecal drug delivery systems (IDDS).
- Conditions
- Chronic Pain, Intractable Pain, Back Pain
- Trial name
- TRANSIT (NCT03876158)
- Testing
- Prometra II Programmable Pump system(Flowonix Medical)
- Where
- United States
- Sponsor
- Rush University Medical Center
Opioid Overdose, Drug Overdose
The Rhode Island Prescription and Illicit Drug Study
This study will test the efficacy of a novel drug-checking intervention to prevent fatal and non-fatal overdose among people who use drugs (PWUD), who are 18-65 years old at the time of enrollment.
- Trial name
- RAPIDS (NCT04372238)
- Testing
- RAPIDS Intervention, Standard OEND
- Where
- United States
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- Brown University
Shoulder Arthroscopy, Knee Arthroscopy
Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery
The purpose of this research is to investigate the non-opioid (non-narcotic) pain-relieving medications clonidine and gabapentin to see if they decrease the amount of opioid pain medications needed after surgery, thereby reducing…
- Trial name
- NCT01112878
- Testing
- Sugar pill, Gabapentin, Clonidine
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Pain
NeoFent-I Study; Fentanyl Treatment in Newborn Infants; a Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Study
The study will assess the efficacy of fentanyl using a pharmacokinetic/pharmacodynamic (PK/PD) model where the concentration of the drug is related to effect curve (pain score change in response to standardized procedural pain).
- Trial name
- NCT03897452
- Testing
- Fentanyl (5 microgram/ml) prediluted ampoules
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Lund University
Hemiplegia
Passive Mobilisation of Region of Shoulder Joints for Hemiplegic Patient
Hemiplegia is a high prevalence pathology with 1 per 1000 habitants in France. One of these complications is shoulder pain which affects about 35 to 70% of cases.
- Trial name
- ERIAMS (NCT02904148)
- Testing
- Shoulder mobilisation
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Postoperative Pain
Efficacy and Safety of IV Diclofenac (DIV075V)for Pain After Elective Orthopedic Surgery
This study will compare repeated intermittent IV dosing of diclofenac in patient with moderate to severe post-surgical pain from elective orthopedic surgery.
- Trial name
- NCT00507026
- Testing
- IV Diclofenac, IV ketorolac
- Where
- 8 sites in United States
- Volunteers
- 277 people
- Sponsor
- Pfizer
Low Back Pain
Pilot Study to Test the Effectiveness of Combining Conventional and Complementary Medicine to Treat Low Back Pain
This pilot study will determine the feasibility of enrolling participants from different populations for a larger study of low back pain (LBP) treatment.
- Trial name
- NCT00118859
- Testing
- Integrative care for low back pain, Conventional treatment for low back pain
- Volunteers
- 60 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Algoneurodystrophy, Amputation
Analgesic Amputation for Algodystrophy: Feedback From a Case Series
What is the aim of the research? The study aims to describe the time interval between amputation for post-traumatic complex regional pain syndrome (CRPS) and functional prosthetic fitting of the amputated limb, within a series of…
- Trial name
- AMPUTALGO (NCT07364266)
- Testing
- describe the time interval between amputation for post-traumatic algodystrophy and functional prosthetic fitting of the amputated limb
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Brest
Endometriosis
A Study to Test Whether Study Drug BAY1128688 Brings Pain Relief to Women With Endometriosis and if so to Get a First Idea Which Dose(s) Work Best
Purpose of the study is to test whether study drug BAY1128688 brings relief for pain to women with endometriosis and if so to get a first impression which dose(s) work best.
- Trial name
- AKRENDO1 (NCT03373422)
- Testing
- BAY1128688
- Where
- 68 sites in Austria, Belgium and 11 more
- Volunteers
- 121 people
- Sponsor
- Bayer
Opioid Use, Marijuana
MEMO-Medical Marijuana and Opioids Study
The study will examine how medical cannabis use affects opioid analgesic use over time, with particular attention to THC/CBD content, HIV outcomes, and severe adverse events.
- Conditions
- Opioid Use, Marijuana, Chronic Pain, HIV/AIDS
- Trial name
- NCT03268551
- Where
- 2 sites in United States
- Volunteers
- 257 people
- Sponsor
- Albert Einstein College of Medicine
Pain, Post-operative
Multimodal Analgesic Protocol to Moderate Acute Pain
With a prospective, observational study assess post-surgery pain levels and patient's use of opioids and other analgesic drugs to moderate pain following third molar surgery.
- Trial name
- NCT03456141
- Testing
- third molar surgery
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pain, Unspecified Adult Solid Tumor, Protocol Specific
Valdecoxib in Treating Chronic Pain in Cancer Patients
RATIONALE: Valdecoxib may be effective in relieving chronic pain in cancer patients. It is not yet known if valdecoxib is effective in treating chronic pain.
- Trial name
- NCT00021996
- Testing
- valdecoxib
- Where
- 2 sites in United States
- Sponsor
- Dana-Farber Cancer Institute
Fibromyalgia
Effect of Revival Soy on Fibromyalgia Pain
Fibromyalgia is characterized by widespread pain that can lead to significant patient dysfunction and economic burden to society.
- Trial name
- NCT00279942
- Testing
- Soy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Drug Overdose
Nasal Naloxone for Narcotic Overdose
The goal of this study is to determine if nasal naloxone is inferior to standard care for naloxone administration in a pre-hospital setting.
- Trial name
- NCT01912573
- Testing
- Intranasal (IN) naloxone, Intravenous (IV) naloxone, Intramuscular (IM) naloxone
- Where
- 3 sites in United States
- Volunteers
- 236 people
- Sponsor
- Judith Feinberg
Opioid Free Anesthesia
A Comparative Study Between Analgesic Effect of Opioid Free and Opioid Based Anesthesia in Radical Nephrectomy Surgery
Patients undergoing nephrectomy have a high incidence of postoperative pain. In the perioperative period, these patients are often treated with patient-controlled opioids, epidural analgesia, or both.
- Trial name
- NCT05312541
- Testing
- pre emptive local anaesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Cancer Pain, Nutrition Disorders
Correlation Between the Analgesic Effect of Fentanyl Transdermal Patches and Nutritional Status in Cancer Pain Patients
The goal of this observational study is to investigate the correlation and quantitative relationship between the analgesic effect of fentanyl transdermal patches in cancer pain patients and their nutritional status.
- Trial name
- NCT06369961
- Testing
- transdermal fentanyl
- Where
- China
- Volunteers
- 151 people
- Sponsor
- Chongqing University Cancer Hospital
Surgery, Pain
Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.
It is very important to decrease the bleeding during nasal septoplasty in order to increase the visibility of the surgical site.
- Trial name
- NCT01964586
- Testing
- Dexmedetomidine, Lidocaine, Adrenaline
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Surgery of Abdominoplasty With Flank Liposuction
Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of…
- Trial name
- NCT01862354
- Testing
- Transverse abdominal plan block, Continuous wound infusion
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Leg Ulcer
Topical Sevoflurane for Treatment of Chronic Leg Ulcers
Patients with painful non-healing leg ulcer will be enrolled in the clinical single-blinded randomized study. The active treatment group will have sevoflurane applied at approximately 1 ml/cm2 at the start of wound treatment, the…
- Trial name
- NCT05303805
- Testing
- Sevoflurane, Cyteal
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
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