Clinical trials: Pain, Medication
Cervical Pain
Effect of Group Pilates and Yoga Exercise Classes for Chronic Cervical Pain
Exercise has been found to be effective in alleviating back and neck pain. Two exercise methods which are available in the community in a group format are Yoga and Pilates.
- Trial name
- Pilates/Yoga (NCT01999283)
- Testing
- Yoga Group Exercise, Pilates Group Mat Exercise
- Where
- 4 sites in United States
- Volunteers
- 88 people
- Sponsor
- Wayne State University
Chronic Female Pelvic Pain Syndrome (Disorder)
The Impact of Integrative Medicine on Patient-Reported Outcomes in Management of Chronic Pelvic Pain
The purpose of this research is to determine if mind and body counseling and training improves quality of life in women undergoing treatment for chronic pelvic pain.
- Trial name
- NCT04773925
- Testing
- Mindfulness counseling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Postoperative Pain, Apical Periodontitis
Effect of Low-level Laser Therapy Versus Calcium Hydroxide Intracanal Medication on Postoperative Pain and Substance P Levels in Patients With Symptomatic Apical Periodontitis
a randomized clinical study to compare the effect of using low level laser therapy versus calcium hydroxide intra-canal medication on: Incidence and intensity of postoperative pain in patients with symptomatic apical…
- Trial name
- NCT04594317
- Testing
- low level laser therapy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nerve Block; Pain Medication
Obturator Nerve Block With Femoral and Sciatic Block
The purpose of this study is to evaluate how many patients require the addition of the obturator nerve block in the recovery room after the total knee surgery.
- Trial name
- NCT01409460
- Testing
- Oburator Nerve block
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Trinity Health Of New England
Pain, Postoperative, Breast Cancer
Postoperative Analgesia Impact of Narcotic Free Anesthesia
The first hypothesis of the study is that substituting fentanyl by esmolol and metoprolol during general anesthesia for patients undergoing mastectomy will result in less pain and less narcotic consumption in the recovery room.
- Conditions
- Pain, Postoperative, Breast Cancer, Postoperative Nausea and Vomiting
- Trial name
- PAINFree (NCT01544959)
- Testing
- fentanyl, beta-blocker (esmolol, metropolol)
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Université de Sherbrooke
Cancers, Pain, Lower Back Pain
Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy
The purpose of this study is to evaluate the long-term safety and tolerability of oxymorphone ER as an analgesic in cancer and lower back pain subjects having chronic moderate to severe pain.
- Trial name
- NCT00904280
- Testing
- Oxymorphone ER
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Pulp Necrosis, Postoperative Pain
Evaluation of Post-operative Pain and Bacterial Load Reduction After Application of Three Intra-canal Medications (Cocoa Husk Versus Calcium Hydroxide With and Without Cocoa) in Necrotic Mandibular First Molar.
The study will aim to evaluate the postoperative pain and bacterial load after application of two intracanal medications in mandibular first molar teeth with necrotic pulp.
- Trial name
- NCT07790796
- Testing
- Root canal treatment with intracanal medication by calcium hydroxide for one week., Root canal treatment with intracanal medication by cocoa husk for one week, Root canal treatment with intracanal medication by calcium hydroxide with cocoa husk for one week.
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Bone Neoplasms
Bonefos and the Consumption of Analgesics
The effect of Bonefos on consumption of analgesics (drugs used for pain treatment) in patients with proven bone metastases.
- Trial name
- BICAM (NCT00909142)
- Testing
- Bonefos (Clodronate, BAY94-8393)
- Where
- Czechia
- Volunteers
- 149 people
- Sponsor
- Bayer
Irritable Bowel Syndrome
Effect of Asimadoline, a Member of a New Medication Class, on Acute Attacks of Pain in Irritable Bowel Syndrome
The treatment of acute pain in patients with irritable bowel symptoms is suboptimal. This is a placebo controlled study of the on demand treatment of pain experienced over a 4 week period in patients with irritable bowel…
- Trial name
- NCT00955994
- Testing
- asimadoline
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Cholecystitis, Appendicitis
Ultrasound Guided Rectus Sheath Block and Transversus Abdominis Plane Block
The current study aimed to assess the efficacy of Dexmedetomidine (DEX) and Dexamethasone as an adjuvant to ultrasound guided TAP and RS block to prolongation of postoperative analgesia and better pain control in children…
- Trial name
- NCT04838379
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Spinal Stenosis
Acupuncture for Lumbar Spinal Stenosis
Acupuncture is widely used to manage chronic low back pain. Mounting evidence suggests the beneficial effects of acupuncture for mitigating chronic low back pain with acceptable minor adverse events.
- Trial name
- NCT01987622
- Testing
- Acupuncture, Usual care
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Herpes Zoster, Pain
The Analgesic Efficacy and Safety of Flurbiprofen Patch in Patients With Herpes Zoster
Herpes zoster (HZ) is characterized by a painful dermatomal rash and significantly affects quality of life, with acute pain increasing the risk of postherpetic neuralgia.
- Trial name
- NCT07370402
- Testing
- Flurbiprofen patch combined with conventional therapy group, Conventional therapy group
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Beijing Tiantan Hospital
Thoracic Diseases, Analgesia
Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery
Comparison of analgesic effects of tramadol, aldolan and morphine under thoracic surgery
- Trial name
- NCT06172920
- Testing
- Tramadol hydrochloride, Aldolan, Morphine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baskent University
Osteoarthritis, Knee
A Controlled Study of an Herbal Topical Patch in Treating Osteoarthritis (OA) of the Knee
An evaluation of the safety and efficacy of an herbal patch in treating osteoarthritis pain of the right or left knee.
- Trial name
- NCT01183624
- Testing
- Herbal Patch
- Where
- 12 sites in China
- Volunteers
- 626 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Pain, Diabetic Neuropathy
Study to Evaluate the Analgesic Efficacy of 28 Days' Oral Administration of AZD2066 Compared With Placebo in Patients With Painful Diabetic Neuropathy
The purpose of this study is to investigate if AZD2066 can relieve the pain arising from painful diabetic neuropathy compared to placebo.
- Trial name
- NCT00857623
- Testing
- AZD2066
- Where
- 19 sites in United States
- Volunteers
- 127 people
- Sponsor
- AstraZeneca
Cancer, Anxiety
Massage Therapy and Port-a-Catheter Insertion
The purpose of this study is to assess the feasibility and efficacy of massage therapy for reducing pre-operative anxiety and post-operative pain among predominantly low income minority cancer patients undergoing surgical…
- Conditions
- Cancer, Anxiety, Pain, Surgery
- Trial name
- NCT00991770
- Testing
- Massage Therapy, Attention Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Medical Center
Pain
Role of Methadone As Co-Opioid Analgesic
Objectives: Primary Objective: To determine whether the addition of low dose methadone to morphine(in the methadone group) has a lower dose escalation index as compared to the morphine alone(in the morphine group) at Day 15 (+/…
- Trial name
- NCT00558870
- Testing
- Morphine, Methadone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
Fibromyalgia
A Study to Assess the Analgesic Efficacy and Safety of ASP0819 in Patients With Fibromyalgia
This study assessed analgesic efficacy of ASP0819 relative to placebo as well as the safety and tolerability. This study assessed treatment differences in physical function as well as the improvements in overall subject status…
- Trial name
- NCT03056690
- Testing
- ASP0819
- Where
- 24 sites in United States
- Volunteers
- 186 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Pain, Postoperative, Acute Pain
Gabapentin as a Pre-emptive Analgesic in Oral and Maxillofacial Surgical Procedures
The purpose of this study is to assess the effectiveness of pre-operative administration of gabapentin 900 mg in management of acute post-operative pain in patients undergoing oral and maxillofacial surgical procedures.
- Conditions
- Pain, Postoperative, Acute Pain, Facial Pain
- Trial name
- NCT02957097
- Testing
- Gabapentin
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Moderate to Severe Pain Due to Diabetic Polyneuropathy
A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy
To show superior analgesic efficacy of OXN PR in addition to a patient's current dose of pregabalin compared to pregabalin alone.
- Trial name
- NCT00944697
- Testing
- Oxycodone Naloxone
- Where
- Germany
- Volunteers
- 98 people
- Sponsor
- Mundipharma Research GmbH & Co KG
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