Clinical trials: Pain, Medication
Opioid-use Disorder, Pain
Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Opioid Use Disorders ("EXPO" Pilot Trial)
The purpose of this pilot trial is to determine the feasibility of integrating exercise and psychotherapy that is specifically targeted to reducing and managing pain into residential drug treatment programs.
- Trial name
- NCT04736550
- Testing
- Exercise, Psychotherapy for Pain (I-STOP)
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Case Western Reserve University
Shoulder Pain
Postoperative Analgesic Effect of Infraspinatus-teres Minor Inter-fascial Block in Patients Undergoing Shoulder Surgery
It is proposed to investigate the effectiveness of ultrasound-guided intertrochanteric block of the infraspinatus minor round myofascial block not inferior to the interosseous groove brachial plexus nerve block in postoperative…
- Trial name
- NCT06240884
- Testing
- Infraspinatus-teres minor interfascial block, interscalene block
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
Analgesia
IPACK or Selective Tibial Nerve Block for ACL Reconstruction With an Adductor Canal Block
The purpose of this study is to compare the analgesic efficacy of the combination of an adductor canal and selective tibial nerve blocks versus adductor canal block and IPACK after ACL reconstruction under general anaesthesia.
- Trial name
- TIPACK (NCT05303233)
- Testing
- Selective tibial nerve block, IPACK
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Nerve Block, Neuromuscular Blockade
LIA vs. LIA + ACB-iPACK Block for Total Knee Arthroplasty
LIA is the mainstay of postoperative analgesia in patients having knee arthroplasty. The combination of ACB-iPACK blocks has also been proposed as an effective analgesic modality for total knee arthroplasty.
- Trial name
- NCT04808947
- Testing
- Local infiltration analgesia, Ultrasound-guided adductor canal block
- Volunteers
- 60 people
- Sponsor
- Women's College Hospital
Cervical Spine Surgery
Analgesic Efficacy of the Novel Intra- Semispinal Fascial Plane Block in Posterior Cervical Spine Surgery
Posterior cervical spine surgery often requires a large posterior midline incision, resulting in poorly controlled postoperative pain, which arises from iatrogenic mechanical damage, intraoperative retraction, and resection to…
- Trial name
- NCT04974658
- Testing
- Inter-semispinal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Dental Anxiety, Dental Pain
Nonpharmacologic Reduction of Periprocedural Distress and Drug Use
Objectives of this Phase I pilot trial are to provide data towards assessing and facilitating feasibility of a larger scale Phase II trial in which the effects of a calmative Comfort Talk® app can be unequivocally evaluated.
- Conditions
- Dental Anxiety, Dental Pain, Drug Use, Opioid Use
- Trial name
- NCT03328208
- Testing
- Comfort Talk® app, White Noise app
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Hypnalgesics, LLC
Renal Colic
Transcutaneous Electrical Nerve Stimulation Treatment of Renal Colic
The aim of the present trial was to investigate the analgesic efficacy and safety of Transcutaneous electrical nerve stimulation treatment in patients with renal colic within the emergency department.
- Trial name
- NCT03237208
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Adiyaman University Research Hospital
Coronary Heart Disease, Angina Pectoris
Safety Study of Kudiezi(Yueanxin,a Chinese Medicine Injection)Used in Hospitals in China
This study was advocated by institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences in October 2011.
- Conditions
- Coronary Heart Disease, Angina Pectoris, Stroke
- Trial name
- NCT01781676
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Acute Pain
Efficacy of XP20B Following Bunionectomy Surgery
The purpose of this study is to determine if XP20B is an effective treatment for the relief of pain following bunionectomy surgery.
- Trial name
- NCT00655291
- Testing
- XP20B
- Where
- 6 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Xanodyne Pharmaceuticals
Solid Carcinoma, 5-Fluorouracil Toxicity
Prevention of Chest Pain in Chemo-treated Cancer Patients
This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment…
- Conditions
- Solid Carcinoma, 5-Fluorouracil Toxicity, Cardiotoxicity, Chemotherapeutic Toxicity
- Trial name
- CATCH (NCT03486340)
- Testing
- Cardiologic assessment
- Where
- Denmark
- Volunteers
- 218 people
- Sponsor
- Vejle Hospital
Abuse, Drug, Pain
THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy
The purpose of this research is to assess the impact of CBD on the effects of THC.
- Trial name
- THC-REDUX (NCT06859710)
- Testing
- THC, CBD 20 mg, CBD 40 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Premature Birth, Newborn
Pain Management in Neonatal Intensive Care Units by Studying the Autonomic Balance
Fight against the pain caused by the disease or by the diagnostic and therapeutic procedures is a daily and essential concern for the caregiver neonatologist.
- Trial name
- NIPE-DOL (NCT02764424)
- Testing
- NIPE (MDoloris®)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neuralgia, Spinal Cord Injury
Symptom Based Treatment of Neuropathic Pain
1. Neuropathic pain in spinal cord injured patients 1. Inclusion criteria pain intensity, visual analogue scale > 3 a LANSS (Leeds assessment of neuropathic symptoms and signs) score of 12 and above aged ≥20 2.
- Trial name
- NCT02180880
- Testing
- Pregabalin and Oxcarbazepine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Ju Seok Ryu
Virtual Reality, Drug Sedation
the Effectiveness of Therapeutic Virtual Reality Versus Pharmacological Sedation on Pain and Anxiety During Interventional Cardiology Procedures
Immersion sedation in virtual reality could be an alternative to conventional pharmacological sedation, during interventional cardiology acts on pain and anxiety control.
- Conditions
- Virtual Reality, Drug Sedation, Coronarography, Angiography
- Trial name
- VirtuCardio (NCT05588232)
- Testing
- scheduled outpatient interventions in interventional cardiology
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Elsan
Upper Abdominal Malignancies
Coeliac Plexus vs Splanchnic Nerve Neurolysis for Upper Abdominal Cancer Pain
The goal of this clinical trial is to determine whether Neurolytic Splanchnic Nerve Block (NSNB) reduces pain in adults with upper abdominal malignancies.
- Trial name
- NCT07653906
- Testing
- Neurolytic Coeliac Plexus Block (NCPB), Neurolytic Splanchnic Nerve Block (NSNB)
- Where
- Bangladesh
- Volunteers
- 44 people
- Sponsor
- Bangladesh Medical University
Coronary Artery Disease, Angina Pectoris
Sirolimus-eluting Stents With Biodegradable Polymer Versus an Everolimus-eluting Stents
Coronary artery stents have improved the safety and efficacy of percutaneous coronary intervention for coronary artery disease. Drug-eluting stents have been shown to decrease neointimal hyperplasia and to reduce the rate of…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Myocardial Infarction
- Trial name
- NCT01443104
- Testing
- Sirolimus-eluting stent with a bioresorbable polymer (Orsiro), Everolimus-eluting stent with a durable polymer
- Where
- 9 sites in Switzerland
- Volunteers
- 2,119 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Perioperative Pain
Pain Control Without Opioids
Adequate outpatient pain control after uncomplicated laparoscopic appendectomy or cholecystectomy can be achieved with minimal breakthrough drugs when used in combination with around the clock non-opioid medications.
- Trial name
- NCT04813991
- Testing
- Ibuprofen 600 mg, OxyCODONE 5 Mg Oral Capsule
- Where
- United States
- Sponsor
- Hackensack Meridian Health
Chronic Pain, Endometriosis
Return to Work in Patients With Chronic Pain
This study aims to evaluate whether a vocational behaviour change ability programme has any additional effect on return to work compared with return to work coordination only in persons with chronic pain.
- Trial name
- UWORKin (NCT03827174)
- Testing
- Return To Work Coordination, Behaviour Change Ability Program
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Uppsala University
Pain, Postoperative
Analgesic Effect of Laser Therapy in Children
Pain management after tonsillectomy could be challenging, with different protocols and various outcome depending on individual patient; moreover, odynophagia due to surgery can, in extreme cases, lead to block oral fluid intake…
- Trial name
- NCT04693208
- Testing
- Laser therapy
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS Burlo Garofolo
Rotator Cuff Tendinitis, Chronic Pain
Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy?
The hypothesis of the present study is that in patients with rotator cuff tendinopathy a specific pharmacological blocking of peripheral glutamate-receptor N-methyl-d-aspartate receptor type1 (NMDAR) glutamate receptors will…
- Trial name
- NCT02967640
- Testing
- Ketalar, NaCl 9%
- Where
- Norway
- Volunteers
- 14 people
- Sponsor
- Helse Møre og Romsdal HF
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