Clinical trials: Pain, Medication
Pain, Procedural, Pain, Acute
Effect of Reflexology on Pain Management in Newborns
Introduction: Approximately 10-14 painful procedures per day are performed in preterm and term infants during the hospital stay in the first week.
- Conditions
- Pain, Procedural, Pain, Acute, Analgesia
- Trial name
- NCT05235893
- Testing
- Reflexology, Sucrose %24, Kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Marmara University
Bariatric Surgery Candidate, Obesity, Morbid
Comparisons of iv Ibuprofen and iv Paracetamol During Bariatric Surgery
The aim of this study is to evaluate and to compare the effectiveness of iv ibuprofen and iv paracetamol during bariatric surgery.
- Trial name
- NCT02778958
- Testing
- paracetamol, ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Pain, Chronic Disease
Medication Adherence Therapy for Opioid Abusing Pain Patients
The purpose of this study is to develop and pilot test a combined behavioral and pharmacological intervention designed to decrease pain, functional interference, and drug abuse while increasing medication adherence.
- Conditions
- Pain, Chronic Disease, Prescription Opioid Abuse
- Trial name
- NCT00249587
- Testing
- Methadone
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Low Back Pain, Recurrent, Healthy
Effects of Sleep Disruption on Drug Response
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration.
- Trial name
- NCT03680287
- Testing
- Within-Subject test of blinded study medication
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Austria Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667016
- Where
- 8 sites in Austria
- Volunteers
- 305 people
- Sponsor
- Biotronik Vertriebs-GmbH
Dexmedetomidine, External Oblique Intercostal Plane Block
Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy
The aim of this study is to compare the analgesic effects of different doses of dexmedetomidine as an adjuvant in external oblique intercostal plane block (EOIPB) in splenectomy.
- Conditions
- Dexmedetomidine, External Oblique Intercostal Plane Block, Splenectomy
- Trial name
- NCT06363578
- Testing
- Dexmedetomidine 0.5 μg/kg, Dexmedetomidine 1 μg/kg
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics (NeuroToP - a COPANA Follow up)
Fundamental aspects of both neurological and reproductive function are established in fetal life, and there is a present increased awareness of the potential effects of fetal exposures on neurodevelopmental and reproductive…
- Conditions
- Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction, Developmental Disability, Adhd
- Trial name
- NeuroToP (NCT07316387)
- Where
- Denmark
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healhty
Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants
This study investigates whether MDMA may have a pain-reducing effect. The effect of MDMA is compared with a placebo (a substance with no active effect).
- Trial name
- MDPS (NCT07494214)
- Testing
- MDMA 25 mg, MDMA 75 mg, MDMA 125 mg
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Heroin Abuse, Opioid Use Disorder
Neuroimaging and CBD for Opioid Use Disorder
The investigators propose an imaging study to investigate the neurobiological effects of CBD (vs placebo) in participants with opioid use disorder who are maintained on methadone.
- Conditions
- Heroin Abuse, Opioid Use Disorder, Substance-Related Disorders, Opioid-Related Disorders
- Trial name
- NCT04567784
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Yasmin Hurd
Osteo Arthritis Knee, Pain, Chronic
Dry Cupping Therapy in Knee Osteoarthritis
Introduction: Knee osteoarthritis (KOA) is the biggest cause of pain and disability worldwide. As a non-pharmacological approach, ventosatherapia has been used to control pain, improve function and quality of life.
- Conditions
- Osteo Arthritis Knee, Pain, Chronic, Pain
- Trial name
- VentosaOA (NCT04331158)
- Testing
- Dry cupping therapy
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Hip Arthroplasty, Anesthesia, Regional
FAB Block vs. Placebo for Hip Arthroplasty Patients
Hip arthroplasty surgery can be associated with significant pain. A regional anesthesia technique, the femoral articular branch block (FAB), has recently been proposed to collectively block terminal femoral and accessory…
- Conditions
- Hip Arthroplasty, Anesthesia, Regional, Femoral Articular Branch Block
- Trial name
- NCT04301687
- Testing
- Femoral Articular Branch Block
- Volunteers
- 95 people
- Sponsor
- Women's College Hospital
Hemorrhoid
Efficacy of Rectal Infiltration of Exparel for Analgesic Benefit Following Hemorrhoidectomy
The purpose of this study is to compare the quality and duration of pain relief after a hemorrhoidectomy, provided by locally administered liposomal bupivacaine versus bupivacaine hcl or control with saline.
- Trial name
- NCT02104414
- Testing
- Exparel, Bupivacaine HCl with Epinephrine, Normal Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Postoperative Pain After Cesarean Section
Comparison of Combined Spinal Epidural Analgesia and Erector Spinae Plane Block After Elective Cesarean Section
Postoperative pain after cesarean section can significantly affect maternal recovery, early mobilization, and patient satisfaction.
- Trial name
- CSEA-ESP-CS (NCT07411521)
- Testing
- Combined Spinal Epidural Analgesia, Ultrasound-Guided Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Postoperative Pain
The Effect Of Ultrasound-guided Modified Pectoral Nerves Block Versus Ketamine Plus Magnesium Infusion On Analgesic Profile In Breast Cancer Surgeries
Background: Postoperative pain is one of the greatest patient concerns following surgery. However, general anesthesia cannot provide adequate postoperative pain control and the routine use of parenteral opioids aggravates…
- Trial name
- NCT04095455
- Testing
- pectoral nerves block group, Ketamine plus magnesium group, Control group
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute, Egypt
Artificial Intelligence, Self-care
AI-Based Education and Menstrual Health Behaviors in Adolescents
This study is designed as a randomized controlled trial aiming to compare the effectiveness of different educational approaches in improving dysmenorrhea self-care and genital hygiene behaviors among adolescent girls.
- Conditions
- Artificial Intelligence, Self-care, Dysmenorrhea, Genital Hygiene Behaviors
- Trial name
- NCT07598929
- Testing
- AI-Supported Mobile Education, Face-to-Face Education, Brochure-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Postoperative Pain
Erector Spinae Plane Block and Oblique Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy
Erector Spinae Plane Block is a newly defined regional anesthesia technique. Its use for many indications has been identified by case reports in the literature.
- Trial name
- NCT03508531
- Testing
- ESP Block, OSTAP block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Effects of the Elements
Effect of Removal of Double Antibiotic Paste on Post Operative Pain
Recruited patients with necrotic pulp after application of double antibiotic paste are assigned to group (XP Endo Finisher file) and group( Passive ultrasonic irrigation) and group (conventional syringe irrigation with side…
- Trial name
- NCT04327453
- Testing
- double antibiotic paste with XP-endo Finisher file, double antibiotic paste with Irrisafe Ultrasonic tip, double antibiotic paste with side vented needle
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Minia University
Postsurgical Pain Due to Third Molar Extraction
An Analgesic Study to of V117957 for the Treatment of Postsurgical Pain Due to Third Molar Extraction
The primary objective of this study is to assess the analgesic properties of an oral dose of V117957 4.5 mg aqueous suspension in the third molar extraction model
- Trial name
- NCT01900795
- Testing
- V117957, Ibuprofen
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Purdue Pharma LP
Addiction, Opioid Dependence
Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction
The purpose of this study is determine the safety, efficacy and tolerability of a novel drug APH-1501 as a pharmacotherapy for Opioid Dependence. The investigators will evaluate the safety of escalating doses APH-1501.
- Conditions
- Addiction, Opioid Dependence, Opioid Withdrawal
- Trial name
- NCT03813095
- Testing
- APH-1501
- Volunteers
- 32 people
- Sponsor
- Aphios
Chronic Rhinosinusitis (CRS)
Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical Trial
The goal of this randomized controlled trial is to evaluate the effectiveness of inhaled methoxyflurane (Penthrox) as an analgesic for patients undergoing minor rhinology and sinus procedures, specifically comparing it to a…
- Trial name
- NCT06750302
- Testing
- Methoxyflurane - Penthrox
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Paul's Hospital, Canada
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.