Clinical trials: Pain, Medication
Crown Lengthening Procedure With Ostectomy
Analgesic Efficacy of Arnica Montana in Comparison With Diclofenac Sodium Following a Periodontal Surgical Procedure
Introduction: Homeopathy is a deep healing, comprehensive and distinct system originally developed by Samuel Hahnemann about 200 years ago.
- Trial name
- NCT03520595
- Testing
- Arnica 200 drug 3 pills,3 times daily for 3 days, Diclofenac Sodium 50mg twice daily
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Varicocelectomy
Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
The demand for safe and effective sedation during spinal anesthesia has increased in recent years, particularly in ambulatory and minor surgical procedures.
- Trial name
- NCT07214701
- Testing
- Ketamine (0.5 mg/kg), Dexmedetomidine
- Volunteers
- 58 people
- Sponsor
- Assiut University
Spinal Stenosis
Acupuncture for Lumbar Spinal Stenosis
Acupuncture is widely used to manage chronic low back pain. Mounting evidence suggests the beneficial effects of acupuncture for mitigating chronic low back pain with acceptable minor adverse events.
- Trial name
- NCT01987622
- Testing
- Acupuncture, Usual care
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Pharmacoresistant Neuropathic Pain
Analgesic Effect of Non Invasive Stimulation : Comparison of rTMS and tDCS Efficacy
The aim of this study is to compare analgesic efficacy of two non invasive techniques based on motor cortex stimulation in neuropathic pain patients.
- Trial name
- NI-MCS (NCT01800136)
- Testing
- Repetitive Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Myofascial Pain Syndrome
Chinese Herbal Medicine for Dialysis-related Myofascial Pain: Study Protocol for A Pilot Randomized Study
Dialysis-related myofascial pain in hemodialysis (HD) patients is an important issue that is associated with many other psychosomatic problems. Effective interventions are required to alleviate pain problems in this group.
- Trial name
- NCT04417101
- Testing
- Chinese Herb
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Cervical Plexus Block
Analgesic Efficacy of Intermediate Cervical Plexus Block in Patients Undergoing Thyroid Surgeries Using Two Bupivacaine Concentrations Non Inferiority Trial
Cervical plexus blocks (CPB) have been widely used to provide effective anesthesia and analgesia during thyroid surgeries. The ICPB was considered a good alternative to the deep CPB with an easier technique and fewer adverse…
- Trial name
- NCT06621836
- Testing
- ICPB H, ICPB - L
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Cairo University
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Nerve Block, Mastectomy
Comparison of Perioperative Opioid Consumption Following Pectoral Nerve Block for Breast Cancer Surgery
In this study, the investigators will compare the intraoperative opioid consumption for patients undergoing breast cancer surgery.
- Trial name
- NCT02741232
- Testing
- Lidocaine 1% with epinephrine 1/400000
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Gingival Recession, Localized, Gingival Recession, Generalized
Pain Management After Free Gingival Graft Surgery
Keratinized gingiva reduces the risk of gingival disease and infection by protecting the tissue around the teeth and is therefore very important for gingival health.
- Conditions
- Gingival Recession, Localized, Gingival Recession, Generalized, Gingival Recession, Mucogingival Surgery
- Trial name
- NCT06675734
- Testing
- diclofenac sodium solution
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Aydın University
Postoperative Pain, Postoperative Nausea and Vomiting
High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain
The purpose of the Study is to test a higher dose of steroids(Dexamethasone) given just prior to surgery in the setting of Fast-Track Knee surgery with Arthroplasty in a group of expected High Pain Responders and the effect on…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Knee Osteoarthritis, Perioperative/Postoperative Complications
- Trial name
- NCT03763734
- Testing
- Dexamethasone
- Where
- 2 sites in Denmark
- Volunteers
- 88 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Postoperative Pain, Analgesia
Genetic Variants and Postoperative Pain
Prospective observational study to analyse patients' pain related outcome after surgery and ist association to genetic variants and non-genetic variables.
- Conditions
- Postoperative Pain, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT03489499
- Where
- Switzerland
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Knee Injuries, Knee Injuries and Disorders
Opioid Reduction Program for Total Knee Replacement Patients
In the context of prescribed opioids, research suggests that increased exposure is associated with long-term opioid use. Orthopedic surgeries are associated with the prescribing of more opioid narcotics than any other surgical…
- Conditions
- Knee Injuries, Knee Injuries and Disorders, Opioid Use
- Trial name
- TKR ORP (NCT05414942)
- Testing
- Opioid Reduction Program
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Tennessee
Osteoarthritis
To Study Generic Diclofenac Sodium Topical Gel 1% in the Treatment of Osteoarthritis of the Knee (Degenerative Joint Disease Presented as Joint Pain, Stiffness, Swelling and Restricted Motion).
This is a Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multiple-Site Clinical Study to Evaluate the Therapeutic Equivalence of Diclofenac Sodium Gel, 1% (Glenmark Pharmaceuticals Ltd) to Voltaren® Gel…
- Trial name
- NCT02596451
- Testing
- Diclofenac Sodium gel, 1%, Voltaren® Gel
- Where
- 44 sites in United States
- Volunteers
- 1,164 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Mastalgia
Mastalgia Treatment: Is There a Role for Osteopathic Manipulative Treatment
There are many current medical treatments for mastalgia, but few have been proven effective. Our objective is to evaluate the effectiveness of osteopathic manipulative treatment as compared to a light touch protocol and standard…
- Trial name
- NCT01643837
- Testing
- Osteopathic Manipulative Treatment, Osteopathic Manipulative Light Touch Protocol (LT)
- Where
- 2 sites in United States
- Sponsor
- New York Institute of Technology
Pain, Urinary Tract Infections
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
This study will evaluate the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as a short term analgesic treatment for the primary symptoms of pain or burning when passing urine associated with…
- Trial name
- NCT01064024
- Testing
- Phenazopyridine Hydrochloride
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Post Operative Pain
Analgesic Efficacy of Saphenous Nerve Block in Total Knee Replacement
We hypothesize that preoperative saphenous nerve block (SNB) in combination with periarticular local infiltration provides better post operative pain relief (POPR) profile as compared to local infiltration alone
- Trial name
- NCT01991288
- Testing
- SNB Saphenous Nerve Block, NSNB Non Saphenous Nerve Block
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Cork University Hospital
Postoperative Pain, Laparoscopic Cholecystectomy
Superficial Plane Blocks for Analgesia After Laparoscopic Cholecystectomy
This prospective, single-center observational study will evaluate postoperative analgesia in adults undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT07834086
- Testing
- Rectointercostal Plane Block, External Oblique-Rectus Abdominis Plane Block, Intravenous Patient-Controlled Analgesia With Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pain
Comparison Between the Analgesic Effectiveness of Virtual Reality and Topical Anesthesia: A Clinical Study
A split-mouth, controlled trial aimed to clinically compare and evaluate the effectiveness of virtual reality versus topical anesthesia gel prior to administration of dental anesthesia injection in reducing the perceived pain and…
- Trial name
- NCT04919421
- Testing
- Dental injection and topical gel application, Dental injection and virtual reality device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Analgesics, Opioid, Anesthesia, General
Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Induction
The goal of this clinical trial is to compare heart rate between the fiberoptic and direct oral intubation using opioid free anesthesia induction.
- Conditions
- Analgesics, Opioid, Anesthesia, General, Heart Rate, Blood Pressure
- Trial name
- NCT06487988
- Testing
- direct conventional laryngoscopy, fiberoptic guided intubation
- Where
- Lebanon
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Fever, Anxiety
LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare System
The positive effects of fever are supported by a number of physiological, pathophysiological and clinical evidence. However, the negative attitude toward fever is widespread and have become persistent.
- Conditions
- Fever, Anxiety, Help-Seeking Behavior, Virus Diseases
- Trial name
- NCT04633603
- Testing
- FeverFriend mobile application
- Where
- Hungary
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Pecs
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