Clinical trials: Pain, Musculoskeletal
Osteoarthritis, Knee
The Comparison of HYAJOINT Plus and Hyalgan Hyaluronan Supplement for Knee Osteoarthritis Pain
The aim of this study was to compare single injection HYAJOINT Plus Synovial Fluid Supplement used on the single and repeat treatment of knee osteoarthritis that has the same safety and effectiveness as three-injection…
- Trial name
- NCT03643588
- Testing
- HYAJOINT Plus, Hyalgan
- Volunteers
- 140 people
- Sponsor
- SciVision Biotech Inc.
Fibromyalgia
Safety and Efficacy of AGN 203818 for Pain Associated With Fibromyalgia Syndrome
This study will explore the safety and effectiveness of different doses of AGN 203818 in treating the pain associated with fibromyalgia syndrome. The study is being conducted in 2 parts.
- Trial name
- NCT00445705
- Testing
- AGN 203818
- Where
- 3 sites in United States, Switzerland and 1 more
- Volunteers
- 211 people
- Sponsor
- Allergan
Pain, Osteoarthritis, Knee
Transdermal Ketoprofen to Treat Mild to Moderate Osteoarthritis (OA) Pain of the Knee
The purpose of the study is to evaluate the safety and effectiveness of the investigational ketoprofen patch with a controlled heating patch, compared to placebo (inactive substance) for the treatment of pain caused by…
- Trial name
- NCT00108810
- Testing
- Transdermal Ketoprofen Patch with CHADD
- Where
- 5 sites in United States
- Volunteers
- 118 people
- Sponsor
- ZARS Pharma Inc.
Spinal Spondyloarthropathies, Axial Spondyloarthritis
Diagnostic Criteria in the Diagnosis of Spinal Spondyloarthropathies in Patients With Chronic Low Back Pain (Study P05320)(COMPLETED)
This is a multi-national, multi-site, observational study to determine which of two strategies, when used by referring physicians is superior in the diagnosis of axial spondyloarthritis (AS) by rheumatologists.
- Trial name
- NCT00726765
- Volunteers
- 1,090 people
- Sponsor
- Merck Sharp & Dohme LLC
Joint Disease
Post Market Clinical Follow-up Study Protocol for DYNASTY® BioFoam® Acetabular Components
Sponsor is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) components marketed in the European Union (EU) .
- Trial name
- NCT02149667
- Testing
- total hip arthroplasty implant
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- MicroPort Orthopedics Inc.
Knee Osteoarthritis, Osteoarthritis of the Knee
Postmarketing Multicenter Study of Intra-Articular DIART ONE / EASYGO ONE for Knee Osteoarthritis
This study looked at how safe and effective a hyaluronic acid-based injection (called DIART ONE or EASYGO ONE) is for people with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Osteoarthritis of the Knee, Degenerative Joint Disease
- Trial name
- NCT06927934
- Where
- Ukraine
- Volunteers
- 55 people
- Sponsor
- Yuria-Pharm
Osteoarthritis, Knee
An Evaluation of a Gender Specific Insole to Provide Relief From Knee Pain Due to Osteoarthritis or General Anterior Knee Pain in Male Subjects When Used in Foot Wear Over a Period of Four Weeks
The primary objective of this trial is to demonstrate the ability of a full length foam insole to provide relief from pain due to osteoarthritis of the knee or general knee pain when used in foot wear for a 4-week period of time.
- Trial name
- NCT03556787
- Testing
- BPI 1000013 (Dr Scholls Insole)
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Bayer
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With Osteoarthritis
The purpose of this study was to compare the analgesic (a drug that relieves pain) effectiveness and safety of OROS hydromorphone HCI (slow release) 8 mg and 16 mg to placebo (no drug) in patients with osteoarthritis (OA).
- Trial name
- NCT00411164
- Testing
- OROS hydromorphone HCI (slow release)
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Myofascial Pain Syndromes
Study to Assess the Efficacy and Safety of Dysport® in Upper Back Myofascial Pain Syndrome
The main purpose of this study is to determine which is the best dose of a drug known as Dysport to give when treating one's type of upper back pain.
- Trial name
- NCT00134810
- Testing
- Botulinum toxin type A
- Where
- 22 sites in Czechia, Germany and 4 more
- Volunteers
- 381 people
- Sponsor
- Ipsen
Low Back Pain, Spondylolisthesis
Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device
Lumbar spinal fusion is commonly performed as a "last resort" in patients with chronic low back pain caused by degenerative changes and instability of the spine.
- Conditions
- Low Back Pain, Spondylolisthesis, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT00095095
- Testing
- Lumbar Interbody Fusion
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 102 people
- Sponsor
- Medtronic Spinal and Biologics
Knee Osteoarthritis
Evaluation of the Evolution of Biological and Imaging Markers of Bone and Cartilage Degradation in Patients With Knee Osteoarthritis Receiving Intra-articular Injections of a Hyaluronan Derivative HYMOVIS®
This pilot study MOKHA is aimed to evaluate the beneficial effect of HYMOVIS® on cartilage of patients suffering of knee osteoarthritis as revealed by using scientifically sound, objective measurements of biological and MRI-based…
- Trial name
- MOKHA (NCT04293861)
- Testing
- HYMOVIS
- Where
- 8 sites in Belgium, France
- Volunteers
- 50 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Sciatica, Herniated Disc
Study of REN-1654 in Patients With Sciatica Pain
The purpose of this study is to gain initial safety and efficacy data on the experimental agent REN-1654 in patients with pain that radiates down the leg(s), and is typical of sciatica (lumbosacral radiculopathy).
- Conditions
- Sciatica, Herniated Disc, Radiculopathy
- Trial name
- NCT00107055
- Testing
- REN-1654
- Where
- 19 sites in United States
- Volunteers
- 72 people
- Sponsor
- Renovis
Osteoarthritis, Rheumatoid Arthritis
Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501, a fixed-dose combination oral tablet of 800 mg ibuprofen and 26.6 mg famotidine for patients that require long-term NSAID treatment.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- NCT00984815
- Testing
- HZT-501
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Amgen
Painful Osteoporotic Vertebral Compression Fractures (VCF)
The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation
The objective of this post market clinical investigation is to evaluate the clinical effectiveness of a minimally invasive vertebral augmentation procedure, Radiofrequency-Targeted Vertebral Augmentation (RF-TVA) as compared to…
- Trial name
- PRIORi-T (NCT01480167)
- Testing
- Vertebral Augmentation (STABILIT), Non-operative Management
- Where
- 6 sites in United States
- Sponsor
- DFINE Inc.
Cervical Kyphosis, Cervical Lordosis
CETIC-I (CEra Traction Improves Cervical Kyphosis -I)
The study is a Prospective, Randomized, Single-blinded, Sham device controlled, Parallel Treatment Grouped, Multi-center, Exploratory Clinical Trial to Evaluate Improvement of Cervical Lordosis and Safety of CGM MB-1701 (Spinal…
- Conditions
- Cervical Kyphosis, Cervical Lordosis, Kyphosis
- Trial name
- NCT05469295
- Testing
- CGM MB-1701 device treatment
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Ceragem Clinical Inc.
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Post Exercise Inflammation, Exercise Recovery
Effect of Maolactin™ FMR on Exercise Recovery, Inflammation, and Muscle Comfort in an Otherwise Healthy Population
This is a double blind, randomised, placebo-controlled, parallel-group trial to evaluate the effect of Maolactin FMR supplementation on post exercise inflammation, exercise recovery and muscle fatigue and pain in an otherwise…
- Conditions
- Post Exercise Inflammation, Exercise Recovery, Muscle Fatigue, Muscle Pain
- Trial name
- NCT06436781
- Testing
- Maolactin, Maltodextrin
- Where
- Australia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Osteoarthritis, Spine
Preliminary Safety and Efficacy of XT-150 in Facet Joint Osteoarthritis
Preliminary safety and efficacy of XT-150 in the synovial capsule of osteoarthritic facet joints in the vertebra of the spine.
- Trial name
- NCT04841512
- Testing
- XT-150
- Where
- Australia
- Sponsor
- Xalud Therapeutics, Inc.
Pain; Bone Neoplasms; Neoplasm Metastasis
A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Malignant Bone Disease.
This single arm study will assess the efficacy and safety of loading doses of intravenous Bondronat in patients with breast cancer and malignant bone disease experiencing moderate to severe bone pain.
- Trial name
- NCT00502736
- Testing
- ibandronate [Bondronat]
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Hoffmann-La Roche