Clinical trials: Pain, Musculoskeletal
Pain, Chronic Pain
Breathwork for Chronic Musculoskeletal Pain
This project is a single-site, single-arm, clinical feasibility trial examining the impact of a single-session, 2-hour connected consciousness breathing with breath retention (CCBR) training for chronic musculoskeletal pain.
- Conditions
- Pain, Chronic Pain, Pain, Chronic, Musculoskeletal Pain
- Trial name
- NCT06455839
- Testing
- Guided Resipiration Mindfulness Therapy (GRMT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Florida State University
Osteoarthritis of the Knee
A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee Marching On for Veterans With Osteoarthritis of the Knee
Knee osteoarthritis (KOA) is one of the most common and disabling conditions among Veterans. Management of KOA is challenging as there are few effective treatments other than joint replacement.
- Trial name
- MOVE-OK (NCT05035810)
- Testing
- Social Incentives and Gamification to Promote Exercise, Corticosteroid Injection given in A-B order, No Social Incentive applied
- Where
- 4 sites in United States
- Volunteers
- 221 people
- Sponsor
- VA Office of Research and Development
Chronic Musculoskeletal Pain, Clinical Communication
Development and Evaluation of an Educational Program for the Management of Chronic Musculoskeletal Pain
A controlled randomized study will be conducted to assess the effectiveness of the educational program before and after its implementation.
- Trial name
- NCT06653114
- Testing
- Education in Chronic Musculoskeletal Pain, Education in Communication Skills
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Musculoskeletal Pain, Pain, Chronic
NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)
Musculoskeletal pain represents the leading cause of disability worldwide. It has been traditionally attributed to peripheral mechanisms, but peripheral damage, inflammation, and psychological factors have failed to significantly…
- Trial name
- NEPAL (NCT02488863)
- Testing
- MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires
- Where
- 4 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Florida
Musculoskeletal Disease, Musculoskeletal Pain
Effectiveness of Motivational Interviewing on Return to Work in People on Sick Leave Due to Musculoskeletal Disorders
Musculoskeletal disorders are the main causes for sickness absence and disability benefits in Norway and the leading causes of disability worldwide.
- Trial name
- MI-NAV (NCT03871712)
- Testing
- Motivational interview, Stratified vocational advice
- Where
- Norway
- Volunteers
- 450 people
- Sponsor
- Oslo Metropolitan University
Chronic Musculoskeletal Pain
Knowledge Beliefs and Expectations of Chronic Musculoskeletal Patients About Their Physiotherapy Program
The purpose of this study is to investigate the knowledge, beliefs and expectations of patients with chronic musculoskeletal pain about their physiotherapy program and the relationship that they built with physiotherapists.
- Trial name
- NCT05707559
- Where
- Greece
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Nociceptive Pain, Musculoskeletal Pain
Clinical Trial of the invisaRED® IR REHAB Device When Used as an Adjunctive Therapy for Nociceptive Musculoskeletal Pain
This is a trial to measure the effectiveness and safety of the invisa-RED® IR REHAB device. The researchers will compare the muscle and joint pain relief of participants who are treated with the real machine, to those treated…
- Trial name
- NCT06393088
- Testing
- IR REHAB
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- IR Technology, LLC
Musculoskeletal Problems, Pain, and QoL in Chiropractors in Relation to Their Working Conditions
Examination of Musculoskeletal System Problems, Pain and Quality of Life Related to Working Conditions in Chiropractors
This research aims to investigate musculoskeletal problems and pain, as well as their effects on the quality of life, arising from the working conditions of chiropractors in their workplaces.
- Trial name
- NCT06519305
- Testing
- Survey completion
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Musculoskeletal Pain
Development of Exercise Training Programme for Older People with Musculoskeletal Pain in the Community
The rate of musculoskeletal pain among older people is increasing worldwide and significantly impacts the quality of life. Regular exercise can help prevent and manage chronic musculoskeletal pain because older individuals who…
- Trial name
- NCT06848972
- Testing
- Structured musculoskeletal exercise programme
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- International Islamic University Malaysia
Fibromyalgia, Myofascial Pain Syndromes
Repeat of: A Study to Evaluate Efficacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With Fibromyalgia
The present trial is designed to assess the safety and efficacy of TNX-102 SL 2.8 mg tablets, taken daily at bedtime after 12 weeks of treatment in patients with fibromyalgia.
- Conditions
- Fibromyalgia, Myofascial Pain Syndromes, Muscular Diseases, Nervous System Diseases
- Trial name
- RE-AFFIRM (NCT02829814)
- Testing
- TNX-102 SL Tablet, 2.8 mg
- Where
- 32 sites in United States
- Volunteers
- 51 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Chronic Pain
The Effectiveness of Continuous Ketamine Infusion (KONTINUE)
There are different treatment for chronic pain. One possible treatment is intravenous infusions of ketamine.
- Trial name
- KONTINUE (NCT06131970)
- Where
- Monaco
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Princesse Grace
Musculoskeletal Pain
Evaluation of the "Intranasal Fentanyl" Protocol in Pediatric Surgical Emergencies at Strasbourg University Hospital
Emergency trauma departments receive thousands of patients each year whose main symptom is pain. In recent years, intranasal fentanyl (FIN) has entered the therapeutic arsenal to treat pain in the emergency department.
- Trial name
- TraumaDol (NCT06832046)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Low Back Pain, Neck Pain
Which Model of Care is the Most Cost-effective in the Treatment of Musculoskeletal Disorders?
As musculoskeletal disorders (MSKDs) reach epidemic proportions in Canada, access to the public health system for those who suffer from them is increasingly difficult.
- Conditions
- Low Back Pain, Neck Pain, Anterior Knee Pain Syndrome, Rotator-cuff Related Shoulder Pain
- Trial name
- Edu1st (NCT06832852)
- Testing
- Stepped care, Rehabilitation Care, Medical Care
- Where
- Canada
- Volunteers
- 369 people
- Sponsor
- Laval University
Chronic Primary Pain, Musculoskeletal Pain
Facilitators and Barriers in Neuroscience-based Pain Education Programmes in Primary Care Physiotherapy
The new approach in pain neuroscience education (PNE) requires specific training for the physiotherapists in charge of applying it.
- Conditions
- Chronic Primary Pain, Musculoskeletal Pain, Fibromyalgia
- Trial name
- NCT05860816
- Testing
- Survey
- Where
- Spain
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Castilla-León Health Service
Fibromyalgia, Myofascial Pain Syndrome
Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia
This study evaluated whether Fibromyalgia Integrative Training program for Teens (FIT Teens), a combined cognitive behavioral therapy and neuromuscular exercise training program is more effective in reducing disability in…
- Conditions
- Fibromyalgia, Myofascial Pain Syndrome, Muscular Diseases, Musculoskeletal Disease
- Trial name
- FIT Teens (NCT03268421)
- Testing
- Fibromyalgia Integrative Training for Teens, Cognitive Behavioral Therapy, Graded Aerobic Exercise
- Where
- 7 sites in United States, Canada
- Volunteers
- 389 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Musculoskeletal Diseases or Conditions, Musculoskeletal Disorders
Effects of Musculoskeletal Rehabilitation Courses on Work Ability
The goal of this observational study is to learn about the effects of two different musculoskeletal rehabilitation programs in working-age people with musculoskeletal disorders.
- Trial name
- NCT06749509
- Testing
- Face-to-face musculoskeletal rehabilitation, Musculoskeletal telerehabilitation, Controls
- Where
- Finland
- Volunteers
- 480 people
- Sponsor
- Social Insurance Institution, Finland
Fibromyalgia, Myofascial Pain Syndromes
A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgia
The use of low-dose CBP dosed nightly at bedtime for FM was supported by the results of Tonix' TNX-CY-F202 Phase 2b study (also referred to as the BESTFIT Study).
- Conditions
- Fibromyalgia, Myofascial Pain Syndromes, Muscular Diseases, Musculoskeletal Diseases
- Trial name
- AFFIRM (NCT02436096)
- Testing
- TNX-102 SL Tablet, 2.8mg
- Where
- 35 sites in United States
- Volunteers
- 519 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Well-Being, Psychological, Work Injury
Eastern Principles Acceptance and Commitment Therapy For Injury Prevention Among Nurses and Nursing Aides
This clinical trial will evaluate the effectivness of an Eastern Principles Acceptance and Commitment Therapy intervention (EPACT) relative to an estabished traditional Western-based Acceptance and Commitment Therapy intervention…
- Conditions
- Well-Being, Psychological, Work Injury, Musculoskeletal Pain, High Frequency Heart Rate Variability
- Trial name
- NCT06813495
- Testing
- Eastern Principles Acceptance and Commitment Therapy for Nurses and Nursing Aids (EPACT NNA), Acceptance and Commitment Therapy for Nurses and Nursing Aids (ACT NNA)
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Bowling Green State University
Anterior Knee Pain
Effects of Training Frequency on Patellofemoral Pain Rehabilitation.
This clinical trial aims to determine the optimal frequency of exercise therapy for improving pain, function, and quality of life in participants with patellofemoral pain.
- Trial name
- ETFRPPRRCT (NCT06808386)
- Testing
- Strengthening 2 times per week, Strengthening 3 times per week
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- University of Nove de Julho
Musculoskeletal Pain, Chronic Shoulder Pain
Digital Versus Conventional Physical Therapy for Chronic Shoulder Tendinopathy
This is a single-center, prospective, randomised, controlled study, with two parallel groups, designed to assess the clinical impact of a digital exercise program against conventional rehabilitation for shoulder tendonitis.
- Conditions
- Musculoskeletal Pain, Chronic Shoulder Pain, Shoulder Tendinopathy
- Trial name
- NCT04636528
- Testing
- Digital rehabilitation, Conventional rehabilitation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Sword Health, SA