Clinical trials: Pain, Musculoskeletal
Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome
Efficacy of Pregabalin in Patients With Radicular Pain
The purpose of this study is to evaluate whether pregabalin is effective in reducing the pain in patients who present with radicular pain due to a herniated disc, spinal stenosis or failed back surgery syndrome.
- Conditions
- Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome, Spinal Stenosis, Herniated Disc
- Trial name
- NCT00908375
- Testing
- Pregabalin, Sugar Pill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Northwestern University
Obesity, Knee Osteoarthritis (OA)
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and knee osteoarthritis.
- Trial name
- AMAZE 5 (NCT07481630)
- Testing
- NNC0487-0111
- Where
- 82 sites in United States, Australia and 8 more
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Osteoarthritis, Fibromyalgia
Pilot Study of the Efficacy & Safety of Natural Eggshell Membrane (NEM) for Joint & Connective Tissue Disorders
The purpose of this study was to evaluate the use of the dietary supplement Natural Eggshell Membrane (NEM) for the treatment of joint and connective tissue discomfort, pain, and flexibility.
- Trial name
- NCT00750230
- Testing
- NEM
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- ESM Technologies, LLC
Shoulder Pain, Acupuncture
Efficacy of Acupuncture for Shoulder Pain Based on Remote Point Selection According to the Meridians
This double blind randomized controlled trial investigates the immediate efficacy of acupuncture for shoulder pain using remote point selection based on meridian theory.
- Conditions
- Shoulder Pain, Acupuncture, Meridians
- Trial name
- NCT06939309
- Testing
- Acupuncture, Rehabilitation
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- China Medical University Hospital
Sprain, Strain
Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain
The purpose of this study is to evaluate the effect of a ketoprofen topical patch on the pain associated with ankle sprain or strain.
- Trial name
- NCT00351104
- Testing
- Ketoprofen Topical Patch 20%
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Alkemira SA
Chronic Low Back Pain, Chronic Sciatica
A Zhineng Qigong Intervention for Patients With Chronic Low Back Pain and/or Leg Pain
The purpose of this study is to evaluate a Zhineng Qigong intervention for patients with chronic low back pain and/or leg pain, and to test feasibility aspects.
- Conditions
- Chronic Low Back Pain, Chronic Sciatica, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- NCT04520334
- Testing
- Zhineng Qigong intervention
- Where
- 9 sites in Sweden
- Volunteers
- 55 people
- Sponsor
- Lund University
Osteoarthritis, Knee, Chronic Knee Pain
Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections
Genicular nerve neurolysis (GN) constitutes a relatively novel technique, whereby different chemical compounds (i.e. alcohol, phenol) are injected in close proximity to the genicular nerves of the knee joint, with the intention…
- Trial name
- NCT06000709
- Testing
- 6% aqueous phenol, MethylPREDNISolone 40 MG
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Temporomandibular Disorder, Neck Pain
How is Aerobic Exercise Compared to Localized Pain Relief Exercises in Patients With Jaw Pain and Neck Pain?
Musculoskeletal (MSK) disorders are some of the most burdensome health issues in the world and the leading causes of years living with a disability.
- Trial name
- NCT05232604
- Testing
- Aerobic exercise, Neck motor control exercise
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Hochschule Osnabruck
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Dynamic Quadriceps Muscle Stimulation for Treatment of Patellofemoral Pain
The purpose of this small, pilot study is to evaluate a novel device that uses neuromuscular electrical stimulation to assist quadriceps muscles as a user walks.
- Trial name
- NCT02243332
- Testing
- KneeStim mobile rehabilitation assistance device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Articulate Labs
Knee Osteoarthritis
The Impact of Therapeutic Alliance in the Rehabilitation of Knee Osteoarthritis.
The therapeutic alliance (TA) is the working relationship or positive social bond between the patient and the therapist. TA is based on collaboration, communication, empathy of the therapist and mutual respect.
- Trial name
- ALLIANCE (NCT04390932)
- Testing
- Enhanced TA, Limited TA, Therapeutic exercise protocol.
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- Universidad Catolica de Temuco
Plantar Fasciitis, Heel Pain
Baxter's Nerve Pulsed Radiofrequency Versus Platelet-Rich Plasma Injection or Both Together as a Treatment Modality of Recalcitrant Plantar Fasciitis
Plantar fasciitis is a common condition causing chronic heel pain due to degenerative changes in the tissue supporting the arch of the foot.
- Conditions
- Plantar Fasciitis, Heel Pain, Nerve Compression Syndromes
- Trial name
- NCT07826234
- Testing
- Baxter's Nerve Pulsed Radiofrequency, Autologous Platelet-Rich Plasma Injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Musculoskeletal Pain
The Pain & Stress Interview Study for People With Chronic Pain
The goal of the study is to determine whether a brief, therapeutic interview can help patients improve their pain and health by addressing psychological issues that are known to drive chronic musculoskeletal pain.
- Trial name
- NCT04498663
- Testing
- Emotion- and Relationship-Focused Therapeutic Interview
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Mark A. Lumley
Joint Pain, Stiffness
Finding Early Rheumatoid Arthritis
Research has shown that early aggressive use of medicines may stop rheumatoid arthritis (RA)or slow its damage. The key to this is to find people with early symptoms which could be RA and have them get a diagnosis, treatment and…
- Trial name
- NCT01341314
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Brigham and Women's Hospital
Parkinson Disease, Pilates
Effect of Pilates Application on Abdominal Muscle Function, Core Stability, Musculoskeletal Pain, Quality of Life, Anxiety and Depression in Parkinson's Patients
In this study, it is aimed to investigate the effect of Pilates application on abdominal muscle function, core stability, musculoskeletal pain, quality of life, anxiety and depression in Parkinson's Patients.
- Conditions
- Parkinson Disease, Pilates, Muscle Function
- Trial name
- NCT04619784
- Testing
- Pilates Exercises, control
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Dokuz Eylul University
Osteoarthritis (OA) of the Knee
INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE
The goal of this clinical trial is to evaluate the effectiveness of Neural Ice for pain management associated with knee osteoarthritis in adults aged 22-80 years.
- Trial name
- ICE (NCT06700109)
- Testing
- Neural Ice, Triamcinolone acetate
- Where
- 15 sites in United States
- Volunteers
- 263 people
- Sponsor
- Brixton Biosciences, Inc.
Knee Osteoarthritis
Chronic Knee Pain Study
Specific Aims: 1) To examine differences between AA and white patients with knee OA in willingness to consider knee joint replacement.
- Trial name
- JRPIT (NCT00776932)
- Where
- United States
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Pain, Chronic Pain Syndrome
Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents
The goal of this clinical trial is to learn if adding Shiatsu therapy to standard treatment can improve quality of life in children and adolescents with chronic pain that is not caused by inflammation.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain and Comorbid Emotional Problems, Chronic Pain, Psychogenic
- Trial name
- ShiQoL (NCT06929598)
- Testing
- Shiatsu Therapy
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Tel Aviv University
Fibromyalgia
Effect of Milnacipran on Pain in Fibromyalgia
The investigators want to study the effects of milnacipran treatment on neurotransmitter release in fibromyalgia.
- Trial name
- Forest (NCT01288807)
- Testing
- Milnacipram
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Diego
Haemophilia
Effectiveness of the Myofascial Therapy in the Hemophilic Arthropathy of Ankle
Randomized clinical trial to assess the efficacy of a treatment protocol applied fascial therapy in patients with hemophilic arthropathy ankle, oriented to know and describe the observed differences on the dependent variables…
- Trial name
- NCT02825667
- Testing
- Physiotherapy sessions
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Real Fundación Victoria Eugenia
Osteoarthritis, Rheumatoid Arthritis
Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain
The purpose of this study is to assess the efficacy of the buprenorphine transdermal patch (Norspan® or Sovenor® transdermal patch) in patients with chronic non-malignant pain of moderate to severe intensity due to…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Lower Back Pain, Joint Pain
- Trial name
- NCT01961271
- Testing
- Buprenorphine transdermal patch
- Where
- 16 sites in Hong Kong, Philippines and 1 more
- Volunteers
- 114 people
- Sponsor
- Mundipharma Pte Ltd.
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