Clinical trials: Pain, Musculoskeletal
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Osteoarthritis, Knee, Osteoarthritis, Hip
Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total joint arthroplasty, as compared to standard of care analgesia.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
- Trial name
- NCT02197273
- Testing
- Liposomal bupivacaine, Standard of care analgesia
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- OhioHealth
Osteoarthritis of the Knee
Apitox, Honeybee Venom Treatment for Osteoarthritis Pain and Inflammation
The study will evaluate Apitox, pure honeybee venom as a treatment for pain and inflammation of osteoarthritis of the knee.
- Trial name
- HBV (NCT00949754)
- Testing
- honeybee venom (Apitoxin (Korea) Apitox (USA))
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Apimeds, Inc.
Degenerative Disc Disease, Low Back Pain
Effectiveness and Safety of Mesenchymal Stem Cell (MSC) Implantation on Degenerative Discus Disease Patients
This study evaluates the effectivity and safety of MSC implantation on Degenerative Disc Disease Patients by assessing visual analog scale, ROM improvement and MRI examination.
- Conditions
- Degenerative Disc Disease, Low Back Pain, Disc Degeneration
- Trial name
- MSC (NCT04499105)
- Testing
- Mesenchymal Stem Cell + NaCl 0,9% 2ml
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- Ahmad Jabir Rahyussalim
Knee Osteoarthritis
Effects of Carbon Dioxide Infrared Laser Moxibustion on Pain and Function in Knee Osteoarthritis
Knee osteoarthritis is a prevalent degenerative joint disorder characterized by chronic knee pain, stiffness, reduced range of motion, and limitations in daily functional activities.
- Trial name
- CILM-KOA (NCT07423182)
- Testing
- Exercise Program for Knee Osteoarthritis, CO2 Infrared Laser Moxibustion (CILM)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Cleft Palate
Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair
The primary objective of this study is to evaluate the efficacy of administering intravenous dexmedetomidine as a single preemptive dose to placebo in reducing the total 24 hour dose of opioids as measured on a weight adjusted…
- Trial name
- NCT02915042
- Testing
- Dexmedetomidine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Adhesive Capsulitis
Effects of Sleeper Stretch and Mobilizations With Movement in Patients With Adhesive Capsulitis
Adhesive capsulitis is a condition characterized by progressive declination range of motion at the glenohumeral joint due to tightness of capsule.
- Trial name
- NCT05649410
- Testing
- mobilization with movement and conventional therapy, sleeper stretch along with conventional therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Low-Dose Radiotherapy for Painful Knee Osteoarthritis
Knee osteoarthritis is a common cause of chronic pain and difficulty with everyday activities, particularly in older adults. Some patients continue to experience clinically relevant knee pain despite medication, therapeutic…
- Trial name
- LDRT-KOA (NCT07886697)
- Testing
- Low-Dose Radiotherapy (LDRT)
- Where
- 4 sites in Spain
- Volunteers
- 283 people
- Sponsor
- Universidad Rey Juan Carlos
Post-polio Syndrome, Physical Activity
Glutathione and Health With Post-Polio Syndrome
In this study, people who have symptoms of post polio will take oral glutathione supplements for three months. Their levels of fatigue, physical activity and sleep efficiency will be assessed.
- Conditions
- Post-polio Syndrome, Physical Activity, Depression, Pain
- Trial name
- NCT01402570
- Testing
- Glutathione
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Low Back Pain
Serum Cytokine Levels in Patients with Lumbal Disc Herniation and Effectiveness of Exercise
The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits.
- Trial name
- NCT04912388
- Testing
- Lumbal stabilization excercises, Conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Axial Spondyloarthritis, Back Pain
Spondyloarthritis Inception Cohort of Southern Denmark
People with axial spondyloarthritis (axSpA) experience a diagnostic delay of 6.5 years in men and up to 8.8 years in women. One of the reasons for the diagnostic delay seems to be limited awareness of the disease characteristics…
- Trial name
- SPINCODE (NCT06337513)
- Testing
- Rehabilitation intervention, Usual care
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- The Danish Center for Expertise in Rheumatology
Rheumatoid Arthritis
Effect of Fish Oil on Surgery Pain After Knee Replacement Patients: Randomized, Prospective, Double Blind, Placebo Control Trial
This is a single-center, prospective, randomized, double blind, placebo control study. The aim of this study is to assess the effect of fish oil capsules on pain intensity and postoperative analgesics consumption in patients…
- Trial name
- EFOPaKR-01 (NCT01274910)
- Testing
- EPAX 6000 EE 1000mg (0.6 gr DHA+EPA)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Trigger Point Pain, Myofascial
Effect of Dry Needling on Muscle Mechanical Properties and Muscle Contractility in Latent Trigger Points
The purpose of this study is to determine whether application of Dry Needling (DN) is effective for improved Muscle Mechanical Properties and Muscle Contractility in Latent Trigger Points point (LTrP) of upper trapezius.
- Trial name
- NCT04466813
- Testing
- Intervention-Dry Needling, Control-Dry Needling
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Temporomandibular Disorder, TMJ Disc Displacement With Reduction
Telerehabilitation for TMD
This study will compare after physical therapy for Temporomandibular Disorders (TMD) performed either in-person or virtually using telerehabilitation.
- Conditions
- Temporomandibular Disorder, TMJ Disc Displacement With Reduction, TMJ Disc Displacement Without Reduction, Masticatory Myofascial Pain
- Trial name
- NCT05318313
- Testing
- Telerehabilitation
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- University of Minnesota
Knee Osteoarthritis (Knee OA)
To Assess the Effect of 336 Days Exposure of Paractin® on Pain & Disease Progression in Patients Suffering From Osteoarthritis of Knee Joint.
Sponsor aimed to study hydroalcoholic extract of Andrographis paniculata (for its effect on OA disease progression in OA patients with moderate to severe knee OA.
- Trial name
- NCT04833946
- Testing
- Andrographis paniculata [150 mg], Microcrystalline Cellulose (MCC)
- Where
- 5 sites in India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Pain, Bone Neoplasm
A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease.
This single arm study will assess the efficacy of loading doses of intravenous Bondronat in reducing pain in patients with breast cancer and metastatic bone disease experiencing moderate to severe bone pain.
- Conditions
- Pain, Bone Neoplasm, Neoplasm Metastasis
- Trial name
- NCT00478270
- Testing
- ibandronate [Bondronat]
- Where
- 6 sites in Greece
- Sponsor
- Hoffmann-La Roche
Musculoskeletal Pain, Cannabis Use
Medical Cannabis Against Chronic Musculoskeletal Pain: a Mixed Methods Study.
Despite many pharmaceutical options, there are no optimal treatments for Chronic musculoskeletal pain (CMP). Although many Canadians use medical cannabis (MC; legally authorized) to relieve their pain, there are no firm…
- Trial name
- NCT05210660
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- CHU de Quebec-Universite Laval
Fibromyalgia
Passive Body Heating, Sleep and Fibromyalgia
Objectives: To assess the effect of passive body heating on the sleep pattern of patients with fibromyalgia. Methods: Six menopausal women diagnosed with fibromyalgia according to criteria determined by the American College of…
- Trial name
- NCT01557062
- Testing
- Polysomnography, Teperature measure, Fibromyalgia Impact questionary
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of São Paulo
Knee Osteoarthritis
Effectiveness of Exercise Plus Pain Neuroscience Education on Brain Function in Knee Osteoarthritis
A three-arm randomized controlled trial will be conducted. Fifty-nine participants with KOA will be recruited in a 1:1:1 ratio. Assessor, and statistician will be blinded to group allocation.
- Trial name
- NCT06482970
- Testing
- Neuromuscular exercise plus pain neuroscience education, Neuromuscular exercise
- Volunteers
- 57 people
- Sponsor
- Universidad Santo Tomas, Chile
Sacroiliac Joint Somatic Dysfunction, Sacroiliac; Spondylitis
Sacroiliac Joint Fusion Comparison Study
Patients diagnosed with chronic SIJ pain that can be treated by sacroiliac joint fusion or radiofrequency ablation. The radio frequency ablation is performed using either conventional or "cooled" techniques aimed at the S1-S3…
- Trial name
- NCT03230279
- Testing
- Sacroiliac joint fusion, Sacroiliac joint radiofrequency ablation
- Sponsor
- Ochsner Health System
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