Clinical trials: Pain, Musculoskeletal
Lumbar Spinal Stenosis
REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain
The purpose of this study is to evaluate the effectiveness and safety of the use of Aurora Spine ZIP™ MIS Interspinous Fusion System and bone graft material in fusion in patients with chronic low back pain that present with…
- Trial name
- Refine (NCT05504499)
- Testing
- Interspinous Fusion
- Where
- 10 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pacific Research Institute
Patellofemoral Pain Syndrome
Comparison of the Efficacy of Russian,Aussie Currents With Isokinetic Exercise Patellofemoral Pain Syndrome
Summary Patellofemoral pain syndrome (PFPS) is defined as common anterior knee pain that occurs during non-traumatic activities such as squatting, running, climbing and climbing stairs.The effectiveness of electrotherapy in…
- Trial name
- NCT04945759
- Testing
- Isokinetick Exercise, Aussie Current, Russion Current, Plasebo Electirical Stimulasyon
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muğla Sıtkı Koçman University
Pain, Musculoskeletal Disorders
Evaluation of a Workplace Intervention for Musculoskeletal Disorders Among Blue-collar Workers
The goal of this feasibility study is to learn if a work environment program to address musculoskeletal disorders and pain, can be implemented and accepted by employees with physical demanding work tasks.
- Trial name
- NCT07466680
- Testing
- GLAD intervention
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Pain, Muscle
Temporal Relationship in Recovery of Muscular Pain and Functional Variables in an Experimental Muscular Pain Model in Hamstrings
Basal measurements are taken in relation to the study variables. Immediately subjects perform eccentric exercise on right hamstrings to develop delayed onset muscle soreness (DOMS).
- Trial name
- NCT03942562
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Osteoarthritis, Knee
Is Botox Effective in Relieving Pain From Knee Osteoarthritis?
Patients with painful knee osteoarthritis will be randomly allocated to one of three groups. Each group will receive a knee injection of: 1) cortisone, 2) low dose Botox, or 3) high dose Botox.
- Trial name
- NCT00279903
- Testing
- Botulinum toxin type A (Btx-A), Cortisone
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Mayo Clinic
Osteoarthritis of the Knee
Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain
Phase 3 randomized, double-blind, placebo- and active comparator-controlled study of TLC599.
- Trial name
- EXCELLENCE (NCT04123561)
- Testing
- TLC599, DSP, Normal Saline
- Where
- 46 sites in United States, Australia
- Volunteers
- 504 people
- Sponsor
- Taiwan Liposome Company
Pain, Lumbar Disc Herniation
The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation
This study will investigate whether two clinical tests can be used to diagnose and predict the outcome in patients with lumbar disc herniation undergoing surgery and non-surgery treatment.
- Conditions
- Pain, Lumbar Disc Herniation, Back Pain, Spinal Diseases
- Trial name
- NCT03832036
- Testing
- Paraspinal Mapping and Quantitative Sensory Pain Test
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Spine Centre of Southern Denmark
Neck Pain, Myofacial Pain Syndrome
Efficacy of Adding Greater Occipital Nerve Block to Trigger Point Injection in Patients With Neck Pain
Study Title: Evaluation of the Effectiveness of Adding Greater Occipital Nerve Block to Trigger Point Injection in Patients with Neck Pain Due to Upper Trapezius Trigger Points: A Single-Blind Randomized Controlled Trial Purpose…
- Conditions
- Neck Pain, Myofacial Pain Syndrome, Trigger Point Pain, Myofascial, Trigger Points
- Trial name
- NCT07058636
- Testing
- 2% Lidocaine HCl + saline, Steroid+lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Joint Diseases, Joint Pain
Subsartorial Nerve Block and Femoral Nerve Block in Total Knee Arthroplasty
The goal of this clinical trial is to compare two different types of nerve blocks in patients undergoing surgery for primary Total Knee Arthroplasty.
- Trial name
- NCT06074744
- Testing
- SSNB + IPACK, FNB + IPACK
- Where
- Switzerland
- Volunteers
- 144 people
- Sponsor
- Luzerner Kantonsspital
Knee Arthropathy, Knee Osteoarthritis
NLR and PLR Levels Following IPACK Block in Knee Arthroplasty
Effect of iPACK block on NLR and PLR following knee arthroplasty
- Conditions
- Knee Arthropathy, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT06304298
- Testing
- 0.9% Sodium Chloride Injection, Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Plantar Fasciitis
Comparing the Effects of Two Foot and Ankle Splints for Foot Pain
Plantar fasciitis (severe pain in the heel) is a common problem that has a significant impact on quality of life. There is some evidence to support the use of orthoses and stretches in the conservative management of plantar…
- Trial name
- NCT02212444
- Testing
- Dynamic elastomeric fabric orthoses (DEFO), Off -the-shelf triplanar orthoses
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Plymouth NHS Trust
Tendinopathy, Pain
Effectiveness of Low-intensity Laser on Pain in Patients With Supraspinatus Tendinopathy
Tendinopathy is an inflammatory process that occurs in and around the tendon when both are affected by a certain injury. In the case of the supraspinatus muscle it is one of the most frequent causes of shoulder pain.
- Trial name
- NCT07013708
- Testing
- Laser
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad Católica de Ávila
Rheumatoid Arthritis
Central Aspects of Pain in Rheumatoid Arthritis
This study seeks to measure the psychometric properties of a newly developed Central Aspects of Pain in Rheumatoid Arthritis (CAP-RA) questionnaire, and investigate the ability of this questionnaire to measure central mechanisms…
- Trial name
- CAP-RA (NCT04515589)
- Where
- United Kingdom
- Volunteers
- 95 people
- Sponsor
- University of Nottingham
Pain
Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain
Open-Label, Safety Study to evaluate the long-term safety of Kadian NT (ALO-01) administered for up to 12 months.
- Trial name
- NCT00415597
- Testing
- ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride ER)
- Where
- 58 sites in United States
- Volunteers
- 467 people
- Sponsor
- Pfizer
Myofascial Pain Syndromes
Study Evaluating Heated Lidocaine/Tetracaine Patch in Patients With Pain Associated With Myofascial Trigger Points
The purpose of this pilot study is to explore the potential usefulness of a heated lidocaine 70 mg and tetracaine 70 mg topical patch for the treatment of pain associated with myofascial trigger points.
- Trial name
- NCT01106989
- Testing
- Heated lidocaine/tetracaine patch
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ZARS Pharma Inc.
Degenerative Disc Disease, Pain
Efficacy of Intradiscal Injection of Viable Placental Tissue Extract in Subjects With One or Two Level, Symptomatic Lumbar Intervertebral Disc Degeneration
Dr. Parker (the "Investigator") and Semmes Murphey Foundation ("Foundation") are conducting a study of outcomes and safety associated with degenerative discs at Semmes-Murphey Clinic, P.C. ("Semmes-Murphey").
- Trial name
- NCT02379689
- Testing
- Injectable placental tissue extract called BioDGenesis (Active Product)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Semmes-Murphey Foundation
Rheumatoid Arthritis
Treatment of Early Aggressive Rheumatoid Arthritis (TEAR)
The purpose of this study is to 1)to determine if it is better to treat all early RA patients with methotrexate in combination with hydroxychloroquine plus sulfasalazine or in combination with etanercept or reserve this treatment…
- Trial name
- TEAR (NCT00259610)
- Testing
- methotrexate, sulfasalazine, hydroxychloroquine
- Where
- United States
- Volunteers
- 755 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis, Back Pain
A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to Osteoarthritis
The purpose of this study is to compare oxycodone/naloxone combination tablet and codeine/paracetamol tablets in the treatment of moderate to severe chronic low back pain or pain due to osteoarthritis.
- Trial name
- NCT00784810
- Testing
- Oxycodone/Naloxone, Codeine/Paracetamol
- Where
- United Kingdom
- Volunteers
- 247 people
- Sponsor
- Napp Pharmaceuticals Limited
Musculoskeletal Pain
Urdu Version Of Cornell Musculoskeletal Discomfort Questionnaire: Reliability And Validity Study
The study aims to translate and adapt Cornell Musculoskeletal Discomfort Questionnaire cross-culturally into the Urdu language for the Pakistani population for investigating the reliability and validity of Cornell Musculoskeletal…
- Trial name
- NCT05207540
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Riphah International University
Morton's Neuroma
A Study to Characterize the Phenotype in Patients With Morton's Neuroma and to Explore the Effect of Local Administration of Xylocaine (Lidocaine)
To characterize the phenotype in patients with Morton's neuroma and to explore the effect of local administration of Xylocaine (lidocaine)
- Trial name
- NCT01298310
- Testing
- Xylocaine
- Where
- Sweden
- Volunteers
- 27 people
- Sponsor
- AstraZeneca
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