Clinical trials: Pain, Musculoskeletal
Post Operative Pain, Knee Osteoarthritis
Cryoneurolysis Prior to Total Knee Arthroplasty
Knee osteoarthritis is a major issue worldwide with limited treatment options. Many patients receive knee joint replacement surgery which is considered effective and safe.
- Conditions
- Post Operative Pain, Knee Osteoarthritis, Opioid-Related Disorders
- Trial name
- NCT05840276
- Testing
- Cryoneurolysis
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Rheumatoid Arthritis
Probing the Rheumatoid Arthritis Brain to Elucidate Central Pain Pathways
Rheumatoid arthritis (RA) is a common disease which is characterised by severe joint inflammation and chronic pain. The discovery of new joint specific treatments has transformed patient outcomes and yet most patients, even those…
- Trial name
- Pro-BEPP (NCT05693532)
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- NHS Greater Glasgow and Clyde
Osteoarthritis, Pain
Femoral Nerve Block Compared to Exparel in Total Knee Replacement
The main objective of the study is to determine if intrarticular injection with liposomal bupivicaine (Exparel) provides better postoperative pain relief and functional outcome following total knee replacement (TKR) than the…
- Trial name
- NCT02473198
- Testing
- Exparel, Femoral Nerve Block Bupivacaine, Toradol
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- The New England Baptist Hospital
Joint Pain, Trouble Balancing
Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Patients who undergo foot and ankle surgery are often made weight-bearing as tolerated (WBAT) in a controlled ankle movement (CAM) boot during their recovery and rehabilitation process.
- Trial name
- NCT03848949
- Testing
- Evenup
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Rush University Medical Center
Knee Osteoarthritis
Wearable Therapeutic Ultrasound Study for Knee Osteoarthritis
The purpose of this study is to evaluate the ability of a wearable therapeutic ultrasound device to reduce pain and increase mobility for subjects with knee osteoarthritis.
- Trial name
- NCT01993693
- Testing
- Ultrasonic Diathermy Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- ZetrOZ, Inc.
Muscle Pain, Joint Pain
Prevalence of Muscle and Nerve and Joint Pain
The purpose of the study is to provide adequate information about the percentage of the main tissue that causing pain in most common spinal disorders either it is muscular, nerve or joint in each spinal parts, that will provide…
- Conditions
- Muscle Pain, Joint Pain, Nerve Pain
- Trial name
- NCT06402448
- Testing
- muscle pain , joint pain and nerve pain.
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Hadeer Gomaa Ebraheem Aly
Non-radiographic Axial Spondyloarthritis
Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis
The purpose of this study was to evaluate the efficacy, safety, and tolerability of secukinumab in Chinese patients with active non-radiographic axial spondyloarthritis (nr-axSpA).
- Trial name
- NCT04732117
- Testing
- Secukinumab
- Where
- 29 sites in China
- Volunteers
- 137 people
- Sponsor
- Novartis Pharmaceuticals
Fibromyalgia, Fibromyalgia Syndrome
Slow Breathing and Resistance Exercise in Fibromyalgia
This randomized controlled trial investigates whether slow breathing techniques influence heart rate variability, exercise self-efficacy, and resistance exercise performance in women with fibromyalgia.
- Trial name
- Breath-fibro (NCT07404384)
- Testing
- Slow Breathing with Visual Pacer, Slow Breathing without Visual Pacer, Spontaneous Breathing (Active Control)
- Where
- 2 sites in Spain
- Volunteers
- 159 people
- Sponsor
- University of Malaga
Fibromyalgia, Chronic Widespread Pain
Effects of and Exploring the Processes of Free Movement Dance as a Physical Therapy Intervention for Female Patients Diagnosed With Chronic Widespread Pain (Including Fibromyalgia).
The study has three parts: Part 1: To evaluate, for adult female patients diagnosed with chronic widespread pain (including fibromyalgia), the effects of Free Movement Dance as an add-on intervention after interdisciplinary pain…
- Trial name
- NCT05282758
- Testing
- Free Movement Dance, Modified person-centred progressive resistance exercise
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Göteborg University
Fibromyalgia
Evaluation of the Sural Nerve With Ultrasonography and Electromyography in Patients With Fibromyalgia
By evaluating the ultrasonographic and electromyographic measurements of the sural nerve in patients with and without a diagnosis of fibromyalgia; to determine the relationship of these measures to each other and to the FIQ…
- Trial name
- NCT04985149
- Testing
- Electromyographic measurement:, Ultrasonographic measurement:
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Lumbar Disc Herniation, Protrusion
Lumbar Kinematics in People With the Low Back Pain
This study evaluates the effect of lumbar disc herniation on kinematics in the lumbopelvic region during daily living activities.
- Conditions
- Lumbar Disc Herniation, Protrusion, Extrusion of Migrated Disc, Hernia
- Trial name
- NCT04417855
- Testing
- G-Walk
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Patellofemoral Pain Syndrome
Impact Of Whole Body Vibration on Planter /Dorsi Flexor Ratio, Pain and Functional Activities in Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) can significantly affect an individual's ability perform to functional activities, such as walking, running, climbing stairs, and sitting for prolonged periods.
- Trial name
- NCT06017778
- Testing
- whole body vibration, traditional exercise group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Painful Osteoarthritis of the Knee
Radiofrequency Ablation of Genicular Nerves for Advanced Osteoarthrosis of the Knee Joint 1 Year Follow-up.
Pharmacological treatment of pain due to osteoarthritis of the knee often proves to be inadequate and/or cause intolerable side effects.
- Trial name
- NCT02688543
- Testing
- RF treatment, radiofrequency ablation, ultrasound
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital General de Jerez de la Frontera
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Patellofemoral Osteoarthritis, Knee Osteoarthritis
FDG PET/MRI Imaging of Patellofemoral Joint Osteoarthritis
This project aims to develop an [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET) / magnetic resonance imaging (MRI) method to locate the painful inflammation in PFJ OA associated with joint loading.
- Conditions
- Patellofemoral Osteoarthritis, Knee Osteoarthritis, Knee Pain, Inflamation
- Trial name
- FDG-PFJOA (NCT07625150)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Fibromyalgia
Fibromyalgia Treatment Trial With Gabapentin and Osteopathic Manipulative Medicine
This study assesses the benefits of intervention with gabapentin, Osteopathic Manipulative Medicine or both for improvement of the symptoms of Fibromyalgia.
- Trial name
- FTTGO (NCT01107574)
- Testing
- Gabapentin, Osteopathic Manipulative Medicine, Gabapentin and Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Good Samaritan Regional Medical Center, Oregon
Neck Pain, Chronic Pain
Inmediate Effect of the Visualization of Action
The observation of actions and motor imagery has demonstrated the activation of certain mechanisms similar to those that occur during active movement, which could induce immediate changes in the amplitudes of movement and…
- Conditions
- Neck Pain, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT03547752
- Testing
- observed action and motor imaginery
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Universidad Autonoma de Madrid
Chronic Pain
Learning to Apply Mindfulness to Pain
The long-term goal of this two-phase project is to reduce chronic pain and co-morbid conditions among Veterans, through scalable, non-pharmacologic evidence-based strategies that are "Veteran-Centric," designed to optimize…
- Trial name
- LAMP (NCT04526158)
- Testing
- Mobile+Group LAMP Mindfulness-Based Intervention, Mobile LAMP Mindfulness-Based Intervention
- Where
- United States
- Volunteers
- 811 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense
Morton Neuroma
Blind and Ultrasound Guided Injection in Morton Neuroma
The aim of this work trial is to compare the effectiveness of blind and ultrasound guided injection for Morton neuroma in order to determine which is more appropriate as the initial procedure in conservative treatment
- Trial name
- NCT03046108
- Testing
- blind injection of Morton neuroma, blind injection of Mepivacaine, blind injection of Triamcinolone
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Complejo Hospitalario Universitario de Granada
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