Clinical trials: Pain, Musculoskeletal
Herniated Disc
Nucleoplasty for Contained Herniated Lumbar Discs
This is a prospective randomised double blind comparison trial. Fifty patients will be included, 25 in the nucleoplasty treatment group, 25 in the control group. The nucleoplasty group will undergo the nucleoplasty treatment.
- Trial name
- NCT00124774
- Testing
- Nucleoplasty
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
Lumbar Disc Herniation With Radiculopathy
Comparison of the Effectiveness of Ultrasound-Guided Periradicular Injections in Patients With Lumbar Radicular Pain
This study aims to compare the effects of different ultrasound-guided periradicular injection solutions in patients with chronic unilateral radicular pain caused by a single-level lumbar disc herniation.
- Trial name
- NCT07771374
- Testing
- Lidocaine Hydrochloride 2% Injection Solution, Dexamethasone 4 Mg/mL Injectable Solution, Dextrose 5% Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Sleep Apnea, Spinal Cord Injuries
Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury
This cross-sectional prospective study will assess the potential association of more severe sleep apnea after spinal cord injury with more intense neuropathic pain, more severe spasticity, and more significant cardiovascular…
- Conditions
- Sleep Apnea, Spinal Cord Injuries, Spasticity, Muscle, Neuropathic Pain
- Trial name
- NCT05687097
- Testing
- Home-based sleep screening test or hospital-unattended sleep screening test, Cardiovascular beat-to-beat monitoring, ECG monitoring
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Chronic Musculoskeletal Pain
PainTrain-AI Pilot: Feasibility, Usability (SUS) and Concept-Shift in Primary Care and a Specialized Setting
This pilot will assess feasibility and usability (SUS) and explore concept shift (reduction of neurophysiology misconceptions) after exposure to a behavioral educational intervention (PainTrain AI), a digital clinical simulation…
- Trial name
- PT-AI Pilot (NCT07497997)
- Testing
- PainTrain-AI Behavioral Training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francesc Valenzuela Pascual
Osteoarthritis, Knee
Standard Versus Novel RFA for Chronic Knee Pain in Osteoarthritis
Brief Summary The goal of this pilot study is to evaluate the feasibility and safety of conducting a randomized comparison of two standard-of-care knee radiofrequency ablation (RFA) techniques in adults with chronic knee pain…
- Trial name
- NCT07674082
- Testing
- Radiofrequency ablation - 3-target technique, Radiofrequency ablation - 6-target technique
- Volunteers
- 24 people
- Sponsor
- Lawson Research Institute of St. Joseph's
Fibromyalgia
Laughter Frequency and Fibromyalgia Symptoms
The purpose of this study is to investigate whether daily laughter frequency is associated with pain intensity and emotional state ratings in individuals who have fibromyalgia syndrome.
- Trial name
- LAF (NCT02957110)
- Testing
- Laughter Frequency
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Walden University
Musculoskeletal Pain
vEAET for Older Veterans With Chronic Musculoskeletal Pain Pilot
An uncontrolled pilot in which Veterans age 60-95 years with chronic musculoskeletal (MSK) pain will undergo Emotional Awareness and Expression Therapy (EAET) delivered over video teleconference (VTC; together vEAET).
- Trial name
- vEAET (NCT04552860)
- Testing
- Emotional Awareness and Expression Therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Posterior Tibial Tendon Insufficiency
Low-Level Laser Therapy and Orthotic Insole in Tibialis Posterior Tendon Insufficiency
The purpose of this study is to compare low-level laser therapy and insole interventions on pain, function and muscle strength in subjects with posterior tendon insufficiency.
- Trial name
- NCT03363074
- Testing
- Orthotic Insole, Low-Level Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Fibromyalgia
Comparison of Ketamine and Esketamine in Patients Suffering From Fibromyalgia Syndrome.
Ketamine and Esketamine intravenous perfusions can modulate chronic pain. The purpose of this study is to determine if Ketamine or Esketamine are favorable for outpatients suffering from fibromyalgia.
- Trial name
- KESK-FIQ (NCT04938713)
- Testing
- Ketamine 50 MG/ML, Esketamine 25 MG/ML
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Charleroi
Hand Osteoarthritis
Splinting to Treat Hand Osteoarthritis
Osteoarthritis (OA) is the most common form of arthritis and the hand is the most frequently affected site.Interphalangeal (IP) joints (the small joints of the fingers) are often involved causing pain, progressive loss of hand…
- Trial name
- SPLINTOA (NCT01249391)
- Testing
- Splinting
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Imperial College London
Patellofemoral Pain Syndrome
Comparing the Effects of Positional Release Technique Versus Myofascial Release Technique of Gluteus Medius
Patellofemoral pain syndrome is a condition of misleading diagnosis. It mostly affects individuals with ages between 18-40 years.
- Trial name
- NCT04667091
- Testing
- Physiotherapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Neuropathic Pain, Fibromyalgia
Deep rTMS (H-coil) for Neuropathic Pain or Fibromyalgia
This study will investigate the efficacy and safety of "deep" rTMS on neuropathic pain or fibromyalgia. It will be randomized and sham controlled and will last 3 months.
- Trial name
- H-FINEP (NCT06250491)
- Testing
- Deep active rTMS with Hesed coil
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Nadine ATTAL
Pain, Stomatognathic Diseases
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
- Conditions
- Pain, Stomatognathic Diseases, Muscle Hypertonia, Myofacial Pain Syndromes
- Trial name
- NCT05021874
- Testing
- Four different physiotherapy treatment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Low Back Pain
Effectiveness of Facet Joint Infiltration in Low Back Pain
The purpose of this study is to evaluate the effectiveness of facet joint infiltration with corticosteroids in the treatment of low back pain due to facet joint osteoarthritis.
- Trial name
- NCT01447160
- Testing
- Cortisone
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Musculoskeletal Pain, Physical Performance
Kinesiophobia and Physical Function in Elderly With Musculoskeletal Pain
This study aims to investigate how kinesiophobia (fear of movement), pain intensity, and physical performance are related in older adults experiencing musculoskeletal pain.
- Conditions
- Musculoskeletal Pain, Physical Performance, Geriatrics, Kinesiophobia
- Trial name
- NCT07272876
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Myofascial Pain Syndrome (MPS)
Effects of Electrical Muscle Stimulation on Myofascial Pain Syndrome
The goal of this clinical trial is to determine if Electrical Muscle Stimulation (EMS) combined with Active Stretching (AS) (EMS+AS) and EMS+AS combined with Trigger Point Pressure Release (TPR) (EMS+AS+TPR) are effective…
- Trial name
- NCT07315776
- Testing
- Therapist-assisted Passive stretching (PS), The two-combination of EMS+AS, Trigger point pressure release (TPR)
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- University of Bath
Pain, Analgesics
Mentholated Cream Containing Oxygenated Glycerol Triesters on Acute Pain of the Muscles and Joints
A single center trial to evaluate the efficacy, tolerance, and acceptability of Oxygenated Glycerol Triesters (OGT) mentholated cream on acute musculoskeletal pain in normal healthy adult volunteers suffering from a recent…
- Trial name
- NCT01387750
- Testing
- Mentholated Cream, Mentholated Cream with OGT
- Volunteers
- 71 people
- Sponsor
- NEMA Research, Inc.
Fibromyalgia
Effectiveness of Acupuncture in Relieving Pain Due to Fibromyalgia
This study will determine the effectiveness of acupuncture versus a placebo in altering brain activity and relieving pain due to fibromyalgia.
- Trial name
- NCT00142597
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Michigan
Chronic Pain
Effects of Biopsychosocial Models Based on Pain or Functionality in the Treatment of Chronic Musculoskeletal Pain
The objective of this study is to evaluate whether a functionality-centered biopsychosocial model can improve clinical outcomes in the care of individuals with chronic musculoskeletal pain treated in a specialized healthcare…
- Trial name
- NCT07544745
- Testing
- Pain-Centered Biopsychosocial Model, Functionality-Centered Biopsychosocial Model Group
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Sao Carlos
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