Clinical trials: Pain, Post Surgical
Pain Postoperative
Analgesic Efficacy of Transmuscular Quadratus Lumborum in Patients Undergoing Total Abdominal Hysterectomy
Patients who have undergone laparotomies often require multimodal postoperative pain regimes. In recent years, abdominal wall blocks have been included to become part of this in order to overcome side effects of systemic opioids…
- Trial name
- NCT02586454
- Testing
- Transmuscular quadratus lumborum block, morphine, ropivacaine
- Where
- Malaysia
- Volunteers
- 64 people
- Sponsor
- Kuala Lumpur General Hospital
Hemorrhoids
Ketamine for Post-operative Analgesia in Hemorrhoidectomy
This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids.
- Trial name
- NCT04248205
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Knee Pain, Knee Chondroplasty
A Randomized Double-Blind Placebo Controlled Trial to Determine the Status of Post Knee Chondroplasty Patients Administered Theramine Versus Placebo in Addition to Post Surgery Analgesics
The purpose of this study will be to show the patient response to analgesics taken post surgery when taken in combination with Theramine as opposed to Theramine-like placebo.
- Trial name
- NCT01534286
- Testing
- Theramine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Targeted Medical Pharma
Postoperative Pain, Acute, Postoperative Pain, Chronic
Recovering From Bariatric Surgery: the Effects of Early Initiated and Supervised Mobilization
The aim is to investigate the effect of early initiated and supervised mobilization continued after discharge as management of postoperative pain and recovery following obesity surgery, including patient experiences, pain coping…
- Conditions
- Postoperative Pain, Acute, Postoperative Pain, Chronic, Bariatric Surgery, Mobilization
- Trial name
- NCT06222151
- Testing
- Intervention 1: Mobilization during hospitalization, Intervention 2: Mobilization the first 4 postoperative weeks, Control group
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Low Back Pain, Cervical Pain
Prospective Study of Post Surgical Continued Spinal Pain Patients
Continued spinal pain following spine surgery is reported in up to 50% of patients. Disability and pain following spine surgery occurs.
- Conditions
- Low Back Pain, Cervical Pain, Neck Disorder, Low Back Disorder
- Trial name
- NCT05401682
- Testing
- Cox chiropractic care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Keiser University College of Chiropractic Medicine
Knee Osteoarthritis
Ambulatory Continuous Adductor Canal Block to Facilitate Same Day Discharge Following Total Knee Arthroplasty: A Pilot Study
Patients scheduled to undergo total knee arthroplasty will receive motor sparing knee blocks with continuous adductor canal block along with multimodal analgesia started pre-operatively and continued into the postoperative…
- Trial name
- NCT02228759
- Testing
- Adductor canal block
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis of the Knee
Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial
To compare the effects of perioperative intravenous Dexamethasone with a placebo on the severity of persistent postsurgical pain after total knee arthroplasty.
- Trial name
- NCT02760459
- Testing
- Dexamethasone, Normal saline solution
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Chiang Mai University
Acute Pain, Arthropathy of Knee
NSS-2-BRIDGE Study for Total Knee and Hip Arthroplasties, Bariatric, and Kidney Transplant Surgeries
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Conditions
- Acute Pain, Arthropathy of Knee, Arthropathy of Hip, Pain, Postoperative
- Trial name
- NCT03834142
- Testing
- NSS-2 Bridge
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jacques E. Chelly
Postoperative Pain
Effect of Passive Ultrasonic Irrigation Activation Cycle on Postoperative Pain
One of the most important goals of root canal treatment is to eliminate bacteria from infected canals. However, conventional irrigation methods combined with mechanical preparation applied during root canal treatment may not be…
- Trial name
- NCT06711029
- Testing
- Conventional needle irrigation, Passive Ultrasonic Irrigation with 3*20 sn, Passive Ultrasonic Irrigation with 6*10 sn
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Esin Özlek
Quality of Recovery, Postoperative Pain
Quality of Recovery Under Low or Standard Pneumoperitoneum Pressure
The use of low-pressure pneumoperitoneum seems to be able to reduce complications such as postoperative pain. However, the quality of evidence for most studies evaluating this relationship is considered low.
- Conditions
- Quality of Recovery, Postoperative Pain, Postoperative Nausea and Vomiting, Neuromuscular Blockade
- Trial name
- NCT05040022
- Testing
- Pneumoperitoneum pressure 10 mmHg, Pneumoperitoneum pressure 14 mmHg
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Shoulder Pain
Interscalene Block Versus Serratus Posterior Superior Intercostal Plane Block for Arthroscopic Shoulder Surgery
This randomized controlled trial aims to compare the effectiveness of interscalene (ISB) and serratus posterior superior intercostal plane block (SPSIP) for postoperative analgesia in patients undergoing elective arthroscopic…
- Trial name
- NCT07311096
- Testing
- Interscalene Brachial Plexus Block (ISB), Serratus Posterior Superior Intercostal Plane Block (SPSIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Female Genital Disease
Comparing Postoperative Pain Following COX-2 and Prostanoids Expression
The purpose of this study is to compare postoperative pain following COX-2 and prostanoids expression in women who underwent laparoscopic surgery for female genital disease in order to evaluate the effect of COX-2 on local…
- Trial name
- COX2RCT (NCT03391570)
- Testing
- COX-2 inhibitor, Preoperative peritoneal biopsy, Single-port laparoscopic surgery
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Pain Management After Surgery
The Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain and Recovery in Children (< 7 Years Old) Undergoing Thoracoscopic Surgery
This study aims to investigate the efficacy of intraoperative intravenous lidocaine infusion on postoperative pain management and recovery in pediatric patients undergoing thoracoscopic pulmonary resection.
- Trial name
- NCT06710405
- Testing
- Lidocaine (drug)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Postoperative Pain
Compare Intraperitoneal Instillation of Bupivacaine+dexmedetomidine Versus Bupivacaine+dexamethasone on Postoperative Pain After Lap Cholecystectomy
Comparison of intraperitoneal instillation of bupivacaine with dexmedetomidine versus bupivacaine with dexamethasone on postoperative pain after laparoscopic cholecystectomy
- Trial name
- NCT06535256
- Testing
- bupivacaine with dexamethasone, bupivacaine with dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Chronic Postsurgical Pain, Chronic Opioid Users
Prevention of Chronic Postsurgical Pain in Chronic Opioid Users:
Chronic opioid users undergoing surgery are at increased risk of CPSP, contributing to long-term disability, decreased quality of life, and prolonged opioid exposure.
- Conditions
- Chronic Postsurgical Pain, Chronic Opioid Users, Transitional Pain Service, Postoperative Pain
- Trial name
- PRE-OPIOID (NCT07717151)
- Testing
- standard institutional perioperative management, specialized teleconsultation
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Quality of Life, Pain, Postoperative
Quality of Recovery After General or Spinal Anesthesia for Inguinal Hernia Repair
Different anesthetic techniques have been proposed for carrying out Inguinal hernia repair, including local anesthesia, regional and general.
- Conditions
- Quality of Life, Pain, Postoperative, Personal Satisfaction, Postoperative Complication
- Trial name
- NCT02696122
- Testing
- Local Group, Spinal anesthesia
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Pain Management, Hemorrhoids Third Degree
Topical Lidocaine 23%/Tetracaine 7% Ointment for Post-Hemorrhoidectomy Analgesia: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a topical ointment containing two local anesthetics (lidocaine 23% and tetracaine 7%) can reduce pain after hemorrhoid surgery in adults.
- Conditions
- Pain Management, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids Second Degree
- Trial name
- NCT07688031
- Testing
- Lidocaine 23% / Tetracaine 7% topical ointment (compounded)
- Where
- Chile
- Volunteers
- 74 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain
RCT to Test Regional Anesthesia Effect on Decreased Opiate Use
Examining use of strong pain medication with the use of perioperative anesthetic medications vs no use of the same perioperative medication
- Trial name
- NCT06989866
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Pain, Nausea
Evaluation of the Effect of the LI4 Cold Application
It is an experimental study conducted to evaluate the effectiveness of cold application to the LI4 point of the hand to reduce/eliminate pain, nausea and anxiety in postoperative patients.
- Conditions
- Pain, Nausea, Anxiety
- Trial name
- LI4 (NCT06357429)
- Testing
- Cold Application
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
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