Clinical trials: Pain, Post Surgical
Postoperative Cognitive Dysfunction, Depressive Symptoms
Perioperative Cognitive Trajectories in Deferred Surgery (CoTELE-SURGE)
Cognition is the way people use their brains to think, understand, remember and make decisions. Cognitive changes are often seen even up to 1 year after surgery.
- Conditions
- Postoperative Cognitive Dysfunction, Depressive Symptoms, Postoperative Pain
- Trial name
- CoTELE-SURGE (NCT04787536)
- Testing
- Non-cardiac surgery
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- McMaster University
Postoperative Pain, Postsurgical Pain
Comparison of the Postoperative Analgesic Efficacy of SAP and SPSIP Blocks in Patients Undergoing Mammoplasty
The aim is to compare the postoperative analgesic efficacy of serratus anterior plane block (SAPB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing mammoplasty surgery.
- Conditions
- Postoperative Pain, Postsurgical Pain, Breast Pain
- Trial name
- SPSIP (NCT07302399)
- Testing
- Serratus Anterior Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Chronic Pain
Comparison of the Efficacy of an Empowered Relief Single-Session Versus Standard Care for Reducing Postoperative Pain Following Elective Orthopedic Surgery: A Randomized Controlled Trial
The purpose of this study is to evaluate the efficacy and acceptability of the French-Canadian version of ER compared to standard care in reducing postoperative pain and improving recovery outcomes at 6-week and 3-month…
- Trial name
- ER-CHUS -Ortho (NCT07392099)
- Testing
- Empowered Relief (ER) consists of a single-session, 2-hour group class.
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Université de Sherbrooke
Post-operative Surgical Pain
Regional Anesthesia (Supra-Orbital and Infra-Orbital Nerve Block) (SION) for Pain Management in Trans-sphenoidal Hypophysectomy
This is a prospective, randomized, blinded, sham controlled regional anesthetic (supra-orbital and infra-orbital nerve block) pain study to compare the systemic postoperative pain medication requirements in patients having…
- Trial name
- SION (NCT04670614)
- Testing
- Nerve Block with ropivicaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anxiety Postoperative, Surgery
Level of Anxiety in Patients Undergoing Invasive Foot Surgery
In recent decades, preoperative anxiety has been studied by numerous authors from different medical-surgical specialties, however, there are no studies in the scientific literature on anxiety prior to surgical procedures in the…
- Trial name
- NCT05948748
- Testing
- foot surgery
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Universidad Católica de Ávila
Postoperative Pain
Analgesia in Knee Arthroscopic Surgery
Pain relief in knee Arthroscopic Surgery is essential for rapid recovery of function.
- Trial name
- NCT02818985
- Testing
- Dexamethasone, Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Prostate Cancer, Men
Impact of Acetazolamide in Reducing Referred Postoperative Pain
Robotic assisted laparoscopic prostatectomy (RALP) is the standard treatment for prostate cancer, due to the benefits of decreased blood loss and length of stay.The procedure involves removing a man's prostate using a minimally…
- Trial name
- NCT04470843
- Testing
- Acetazolamide
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Medical College of Wisconsin
Symptomatic Irreversible Pulpitis
Effect of Cryotherapy on Postoperative Pain
the aim of the study is to evaluate the effect of cryotherapy on postoperative pain in molar teeth with irreversible pulpitis and apical periodontitis
- Trial name
- NCT03716635
- Testing
- cryotherapy, normal saline
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study
The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound…
- Trial name
- NCT00508092
- Testing
- local anesthetic administration
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Royal Berkshire NHS Foundation Trust
Pain, Postoperative Pain
REduced Pain After Bariatric Surgery - Sleeve Gastrectomy
This study aims to analyze the effect of laparoscopic guided transversus abdominis plane (LG-TAP) block compared to placebo for postoperative analgesia following laparoscopic sleeve gastrectomy.
- Conditions
- Pain, Postoperative Pain, Acute Pain, Analgesia
- Trial name
- REPABS-SG (NCT06383234)
- Testing
- LG-TAP block with local anesthetic, LG-TAP block with saline solution, Port site infiltration
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Caudal Anesthesia
Very Low Dose Caudal Morphine for Postoperative Pain Management
This is a chart review. The aim of this study is to investigate the effectiveness and side effects of very low dose morphine administered caudally to children that went to surgical procedures that used caudal anesthesia.
- Trial name
- NCT00938821
- Testing
- Caudal block
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Oklahoma
Ureteropelvic Junction Obstruction, Postoperative Pain
Ketamine Added to Quadratus Lumborum Block for Pain Relief After Infant Pyeloplasty
This prospective randomized study evaluates the effect of adding ketamine to bupivacaine in ultrasound-guided quadratus lumborum (QL) block for postoperative pain management in infants undergoing open pyeloplasty.
- Trial name
- KETA-QLB (NCT07596810)
- Testing
- Ketamine + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Proctological Surgery
Interest in Clonidine in Association With Levobupivacaine Performing a Pudendal Block in Proctological Surgery.
Proctological surgery represents a short duration surgery performed in ambulatory, which causes significant post-operative pain.
- Trial name
- NCT04530903
- Testing
- Clonidine, Levobupivacaine, NaCl 0.9%
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Pain, Postoperative, Breast Cancer
Speeding Recovery From Pain and Opioid Use
Surgical treatment of breast cancer is associated with significant disability, and pain is often reported as a primary cause for declines in the ability to perform activities of daily living.
- Conditions
- Pain, Postoperative, Breast Cancer, Opioid Use, Surgery
- Trial name
- NCT03388814
- Testing
- Local infiltration of bupivacaine, Pectoralis Nerve block
- Sponsor
- Wake Forest University Health Sciences
Post Operative Pain
Analgesic Effect of M-TAPA and TAPB on Laparoscopic Cholesistectomy
Cholecystectomy is the most frequently performed abdominal surgery in developed nations, with laparoscopic cholecystectomy being recognized as the gold standard technique for treating gallstones.
- Trial name
- NCT06662617
- Testing
- modified thoracoabdominal nerve block through perichondrial approach, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Postoperative Pain
Efficacy Parecoxib and Ketorolac as Preemptive Analgesia in Spine Fusion
The purpose of this study is to evaluate the efficacy of Parecoxib and Ketorolac as a preemptive analgesia in patients undergoing lumbar spinal fusion.
- Trial name
- NCT01859585
- Testing
- Parecoxib, Ketorolac
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Prince of Songkla University
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Pain, Postoperative
Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy
This study aims to determine if administration of gabapentin preoperatively followed by a standing postoperative course is effective in reducing and possibly eliminating the use of opioid analgesics following this procedure.
- Trial name
- NCT05024825
- Testing
- Gabapentin, hydrocodone, acetaminophen and ibuprofen
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Umbilical Hernia, Obesity
Abdominal Wall Block Study
Compare the ability of the transversus abdominis plane block (TAPB) and rectus sheath block (RSB) to provide surgical anesthesia for overweight and obese patients undergoing umbilical hernia surgery.
- Trial name
- TAPB (NCT03074240)
- Testing
- TAPB Group, RSB Group, conversion to general anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
Phantom Limb Pain
Massage Therapy for Phantom Limb Pain: Feasibility and Pilot Study
Massage therapy is a treatment self-reported by those with phantom limb pain (PLP) as moderately to extremely effective, but no research to date has been specifically designed to examine such efficacy or effectiveness in this…
- Trial name
- NCT03372668
- Testing
- massage therapy combined with components of mirror therapy
- Volunteers
- 3 people
- Sponsor
- Indiana University
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