Clinical trials: Pain, Post Surgical
Radial Fracture
Radius Fracture Anesthesia and Rehabilitation (RADAR)
Distal fracture of the radial bone is the commonest fracture and is also connected to osteoporosis. Normally the operation is performed under neuroaxial blockade and sedation.
- Trial name
- RADAR (NCT03749174)
- Testing
- Long acting Supraclivicular block vs Short acting Supraclavicular block
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Sahlgrenska University Hospital
Pectus Excavatum, Pain, Postoperative
Sub-Paraspinal Block in Nuss Patients. A Pilot Project
The purpose of this pilot study was to evaluate effectiveness of a novel regional anesthesia technique developed at the investigators institution, as part of a quality improvement initiative, to assist with multilevel thoracic…
- Trial name
- NCT02169297
- Testing
- Ultrasound-guided Sub-Paraspinal Block, PCA only
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic
Total Knee Arthroplasty
Ultrasound-guided Continuous Proximal Adductor Canal vs Continuous Femoral Nerve Block for Postoperative Pain Control and Rehabilitation Following Total Knee Arthroplasty
The purpose of the study is to compare continuous femoral nerve block with continuous proximal adductor canal block for postoperative pain control and rehabilitation.
- Trial name
- NCT02495805
- Testing
- Continuous proximal adductor canal block, Continuous femoral nerve block
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Chronic Post-Surgical Pain
Effect of Perioperative Dexmedetomidine on Chronic Post-Surgical Pain
The goal of this clinical trial is to learn if intranasal dexmedetomidine works to improve sleep quality to treat chronic post-surgical pain (CPSP) in patients undergoing thoracic surgery.
- Trial name
- NCT06849466
- Testing
- Dexmedetomidine, Saline solution
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Peking Union Medical College Hospital
Satisfaction, Pain Management After Surgery
Post-c-section Pain Control Satisfaction with Erector Spinae Simple Block Vs Lateral Quadratus Lumborum Block
The study will compare the difference between the patient's satisfaction after Erector spinae plane block (ESP) and Quadratus Lumborum block lateral approach after caesarean section alone or as part of multimodal analgesia.
- Trial name
- NCT06771466
- Testing
- Bilateral Ultrasound-Guided Erector Spinae Plane Block (group E), Bilateral Ultrasound-guided Quadratus Lumborum, Lateral approach (group Q)
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Wael Sayed El Gharabawy
Analgesic Drugs, Analgesic, Nonopioid
Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia
Currently the prevalent approach to perioperative management of patients is ERAS (Enhanced Recovery After Surgery) concept. This approach includes numerous aspects, among which the perioperative use of multimodal analgesia takes…
- Conditions
- Analgesic Drugs, Analgesic, Nonopioid, Analgesic Efficacy, Analgetic Consumption
- Trial name
- NCT07070050
- Testing
- Ibuprofen continuous infusion, Ibuprofen bolus injection
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
Pain
Efficacy of Lumiracoxib in Relieving Moderate to Severe Post-dental Surgery Pain, Compared to Both Placebo and Celecoxib
This study will assess the safety and efficacy of lumiracoxib 400 mg in relieving moderate to severe post-dental surgery pain, compared to both placebo and celecoxib 400 mg.
- Trial name
- NCT00348491
- Testing
- Lumiracoxib
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Novartis Pharmaceuticals
Colorectal Neoplasms, Aged
Effect of Transversus Abdominis Plane Block Combined With Dexmedetomidine Infusion on the Prognosis in Elderly Patients Undergoing Abdominal Surgery
To compare the prognosis of elderly patients undergoing radical resection of colorectal cancer treated with general anesthesia and general anesthesia combined with transversus abdominis plane block and continuous infusion of…
- Trial name
- NCT04516174
- Testing
- Transversus abdominis plane block using ropivacaine, Dexmedetomidine, Transversus abdominis plane block using saline
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Tiantan Hospital
Benign Prostatic Hyperplasia, Anxiety
Music Intervention During AEEP: A Prospective Randomized Controlled Trial
This prospective randomized controlled study investigates the effect of perioperative music listening on anxiety and postoperative pain in patients undergoing Anatomical Endoscopic Enucleation of the Prostate (AEEP) for benign…
- Conditions
- Benign Prostatic Hyperplasia, Anxiety, Postoperative Pain Management
- Trial name
- AEEP-MUSIC (NCT07255118)
- Testing
- Music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- İrfan Şafak Barlas
Pulp Necrosis
Photo-Activated Disinfection Versus Triple-Antibiotic Paste for Management of Necrotic Young Permanent Anterior Teeth
This study aims to compare regenerative endodontics for necrotic young permanent anterior teeth using oral photo-activated disinfection versus triple antibiotic paste in terms of: 1.
- Trial name
- NCT03763110
- Testing
- Photo Activated Disinfection, antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Postoperative Return of Bowel Function
Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Sections
Postoperative discomfort is a frequently seen adverse event after to caesarean operation. Early mobilization and bonding of the mother and her infant are typically impacted by this phenomenon.
- Trial name
- NCT06433713
- Testing
- Lidocaine IV
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Laminectomy
Esmolol Infusion During Laminectomy: Effect on Quality of Recovery
The purpose of this study is to evaluate the effects of esmolol, a drug which is commonly administered during surgery to help control blood pressure and heart rate, on postoperative pain levels and requirements for pain…
- Trial name
- NCT01179113
- Testing
- Esmolol, Saline
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Cedars-Sinai Medical Center
Preparation of the Implant Site With Piezosurgery vs Drill
Observational Study on the Preparation of the Implant Site With Piezosurgery vs Drill: Comparison Between the Two Methods in Terms of Post-operative Pain, Surgical Times and Operational Advantages
Purpose: Recent advances showed that ultrasonic implant site osteotomy is related with a decreased trauma and a better post operative healing of the surgical site if compared to the traditional drilling techniques.
- Trial name
- NCT03978923
- Testing
- preparation of the implant site with Piezosurgery vs drill
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Postoperative Pain
Ropivacaine Transversus Abdominis Plane Blocks for Cesarean Section Analgesia
With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section).
- Trial name
- TAPROPI (NCT02893423)
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Chronic Postoperative Pain
Effect of Intraoperative Dexmedetomidine on Postoperative Pain in Elderly Patients Undergoing Major Abdominal Surgery: a Secondary Analysis Based on Prospective Data
This study is a secondary analysis of multicenter prospective data, including elderly patients who underwent elective major abdominal surgery between April 2020 and April 2022 from a perioperative database of elderly patients in…
- Trial name
- NCT07744308
- Where
- China
- Volunteers
- 2,754 people
- Sponsor
- Chinese PLA General Hospital
Tonsillectomy
The Effect of Peritonsillar Infiltration of Ketamine and Dexamethasone for Postoperative Pain Relief in Children Following Adenotonsillectomy
The immediate postoperative period after tonsillectomy, , is often difficult. These children frequently have severe pain but postoperative airway edema along with increased sensitivity to the respiratory-depressant effects of…
- Trial name
- NCT01198210
- Testing
- saline, Ketamine, Dexamethasone
- Where
- Iran
- Volunteers
- 160 people
- Sponsor
- Qazvin University Of Medical Sciences
Acute Pain, Chronic Pain
The Role of Cognitive Function and Electroencephalography on Acute and Chronic Pain After Surgery
The project will apply the methods of clinical observation experiment, (1) to collect the cognitive function data preoperatively and early postoperatively, as well as the pain score data at multiple time points pre- and…
- Conditions
- Acute Pain, Chronic Pain, Thoracic Surgery, Electroencephalography
- Trial name
- NCT03761576
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Feng, MD
Postoperative Pain, Psychological Factors
Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
This study investigates the relationship between psychosocial factors, particularly self-esteem and personality traits, and postoperative pain in patients undergoing aesthetic breast surgery.
- Conditions
- Postoperative Pain, Psychological Factors, Breast Surgery, Aesthetic Surgery
- Trial name
- NCT06707818
- Testing
- Preoperative Interventions, Intraoperative Interventions, Postoperative Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Thoracotomy, Hyperalgesia
Central Sensitisation and Postoperative Pain
One out of 10 patients undergoing surgery develops persistent post-surgical pain (PPSP). Unfortunately, available therapies for treating this pain have limited success.
- Conditions
- Thoracotomy, Hyperalgesia, Hyperalgesia, Secondary, Central Sensitisation
- Trial name
- NCT04220697
- Testing
- electroencephalography (EEG), questionnaires, high frequency electrical stimulation of the forearm skin (HFS)
- Where
- 2 sites in Belgium
- Volunteers
- 70 people
- Sponsor
- Université Catholique de Louvain
Pain, Postoperative
An Open-Label Functionality, Safety and Efficacy Study in Patients Undergoing Elective Unilateral Knee Replacement
This study is being performed to evaluate the functionality of a device (Sufentanil NanoTab® PCA System) that has been developed for use by patients to self-administer the ARX-F01 pain medication (Sufentanil NanoTab 15 mcg) for…
- Trial name
- NCT00859313
- Testing
- Sufentanil NanoTab PCA System/15 mcg
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Talphera, Inc
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