Clinical trials: Pain, Post Surgical
Lung Cancer
Bupivacaine Liposome Serrate Anterior Plane Block vs Traditional Thoracic Paravertebral Block
In this study, patients will receive bupivacaine liposome serratus anterior plane block or ropivacaine paraspinal block to manage postoperative pain.
- Trial name
- NCT06135545
- Testing
- Bupivacaine Liposome SAPB, Traditional TPVB
- Where
- China
- Sponsor
- Shiyou Wei
Inflammatory Response, Pain, Postoperative
Dexamethasone and Robotic-assisted Hysterectomy
Robotic-assisted hysterectomy is an alternative to laparoscopic surgery as part of a minimal invasive regimen. Several treatment strategies are followed to improve the overall outcome and minimize surgical stress.
- Conditions
- Inflammatory Response, Pain, Postoperative, Nausea, Postoperative, Incontinence
- Trial name
- NCT04762381
- Testing
- Dexamethasone phosphate
- Where
- Denmark
- Volunteers
- 109 people
- Sponsor
- Herning Hospital
Shoulder Pain, Osteoarthritis of Glenohumeral Joint
Functional and Radiographic Outcomes After Shoulder Surgery
The objective of this study is twofold: First, to determine whether higher levels of pre-operative psychological distress predict worse outcomes after arthroscopic rotator cuff repair; second, to obtain functional outcomes (VAS…
- Conditions
- Shoulder Pain, Osteoarthritis of Glenohumeral Joint, Rotator Cuff Tear Arthropathy
- Trial name
- NCT01405781
- Where
- 2 sites in United States
- Volunteers
- 1,034 people
- Sponsor
- University of Utah
Cervical Surgery, Endonasal Surgery
Effect of Passive Music Therapy Via an App on Anxiety Prevention in ENT Surgery
Music therapy is a controlled method of listening to music, utilizing its physiological, psychological, and emotional effects on humans during the treatment of illness or trauma.
- Conditions
- Cervical Surgery, Endonasal Surgery, Otologic Disease, Oropharyngeal Disease
- Trial name
- MUSICORL (NCT06600919)
- Testing
- Preoperative Music Therapy Session
- Where
- Reunion
- Volunteers
- 500 people
- Sponsor
- Clinique Saint-Vincent
Pain, Postoperative
Evaluation of Efficacy of Lumbar Plexus Bloc After Hip Surgery
Compare lumbar plexus block with ropivacaine 0.475%, 0.4 ml/kg to saline. Each group randomized, includes 30 patients. block performed preoperatively Surgery under general anesthesia.
- Trial name
- NCT00150865
- Testing
- ropivacaine
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Pain, Inflammation
Safety/Efficacy of Nepafenac Punctal Plug Delivery System Compared to Placebo to Control Ocular Pain/Inflammation After Cataract
This is a Phase 2, multi-center, randomized, parallel-arm, double-masked, placebo-controlled study. One (1) to 2 days prior to their scheduled cataract surgery, each study subject will be randomized (2:1) in to one of two…
- Trial name
- NCT03496467
- Testing
- Nepafenac PPDS
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Mati Therapeutics Inc.
Inguinal Hernia, Femoral Hernia
Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations
The study attempts to quantify the relative risks for acute postoperative pain, complications rate, chronic postoperative pain (CPIP) and recurrence rate after different methods of repair of groin, umbilical and incisional hernia…
- Conditions
- Inguinal Hernia, Femoral Hernia, Umbilical Hernia, Ventral Hernia
- Trial name
- NCT05920200
- Testing
- open non-mesh hernia repair, open mesh hernia repair, MIS hernia repair
- Where
- Russia
- Volunteers
- 4,000 people
- Sponsor
- Immanuel Kant Baltic Federal University
Post-operative Pain
Traumeel S for Reduction of Post Operative Pain Following Arthroscopy
The perception of pain is a complex process that is not yet fully understood. With outpatient knee arthroscopy becoming standard of care, postoperative pain management has become increasingly important in caring for patients.
- Trial name
- NCT00307892
- Testing
- Traumeel S: intra-operative irrigation + oral ingestion
- Where
- Israel
- Volunteers
- 98 people
- Sponsor
- Shaare Zedek Medical Center
Postoperative Pain
Optimizing Recovery in Abdominoplasty
The overall purpose of this study is to evaluate the analgesic efficacy of liposomal bupivacaine in optimizing pain control, minimizing the risk of postoperative nausea and vomiting (PONV), and improving recovery after…
- Trial name
- NCT04254692
- Testing
- Liposomal bupivacaine, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Renal Stone
The Efficacy of Peritubal Analgesic Infiltration in Postoperative Pain Following Percutaneous Nephrolithotomy
The investigators aim to investigate the effect of peritubal local anesthetic infiltration on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy.
- Trial name
- NCT04160936
- Testing
- Marcaine Injectable Product
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- Saddam Al Demour
Bypass, Cardiopulmonary
Menthol Massage for Post-Bypass Pain & Anxiety
This randomized controlled trial aims to evaluate the effectiveness of mentholated ointment massage in reducing pain and anxiety levels in patients who have undergone coronary bypass surgery, volunteered to participate in the…
- Trial name
- Menthol Care (NCT07508371)
- Testing
- Menthol Massage, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Opioid Use, Pain, Chronic
Pain AND Opioids After Surgery
The aim of this study is to document the perioperative opioid use and its safety in the UK and countries in Europe and to describe its association with surgical complications, persistent pain and quality of life.
- Conditions
- Opioid Use, Pain, Chronic, Pain, Postoperative, Quality of Life
- Trial name
- PANDOS (NCT05877157)
- Where
- 4 sites in Croatia, United Kingdom
- Volunteers
- 10,000 people
- Sponsor
- University of Aberdeen
Pain, Postoperative
Multimodal Orthognathic Study Comparing Use of Exparel With Standard of Care.
A prospective, randomized clinical trial to determine if using liposomal bupivicaine in maxillary orthognathic procedures can reduce the post-operative use of opioids as well as improving the patient's quality of life, versus…
- Trial name
- NCT06499181
- Testing
- Liposomal bupivacaine, Bupivacain, Epinephrin
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Pain, Postoperative, Neuropathic Pain
Cartography of Allodynic and Hypoasthetic Territories Following TKA
The purpose of this study is to realize a cartography of the allodynic and hypoasthetic territories associated with a neuropathic pain appearing in patients who underwent a Total Knee Arthroplasty (TKA)
- Trial name
- CARTODOL (NCT02828800)
- Testing
- Cartography of allodynic and hypoasthetic territories
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Low Back Pain
Modified Thoracolumbar Interfascial Plane Block Versus Erector Spinae Plane Block For Enhancement Of Quality of Recovery After Lumbar Spine Surgery: A Prospective Randomized Controlled Study.
Aim of study The objective of the current study is to compare the efficacy of ultrasound-guided bilateral modified thoracolumbar interfascial plane (TLIP) block versus erector spinae (ES) block in optimizing early quality of…
- Trial name
- NCT07166900
- Testing
- Modified Thoracolumbar Interfascial Plane Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Fayoum University
Anxiety and Fear, Pain, Postoperative
Virtual Reality as a Digital Premed to Alleviate Pain and Anxiety Preoperatively in Patients Undergoing Spine Surgery
The aim of this research study is to evaluate the impact of immersive VR exposure on preoperative anxiety and pain. Additionally, to assess whether VR intervention would significantly alleviate pain and anxiety levels of patients…
- Conditions
- Anxiety and Fear, Pain, Postoperative, Stress
- Trial name
- NCT06917300
- Testing
- Virtual Reality
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Lodz
Pain, Postoperative, Thoracotomy
Effect of Two Different Plane Blocks on Post-thoracotomy Pain
Thoracotomy is recognized as one of the most painful surgical procedures. This increases the frequency of postoperative pulmonary complications.
- Conditions
- Pain, Postoperative, Thoracotomy, Erector Spinae Plane Block, Serratus Anterior Plane Block
- Trial name
- NCT05083832
- Testing
- Continuous Erector Spina Plane Block vs Continuous Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Post Surgical Pain
Dose Response Study of Dexamethasone in Combination With Bupivacaine 0.25%
When used in conjunction with a local anesthetic, dexamethasone may prolong both the sensory and motor effects of high supraclavicular brachial plexus nerve block (SBP) in arthroscopic shoulder surgery.
- Trial name
- Dex Dose (NCT01690663)
- Testing
- Bupivacaine 0.25%, Dexamethasone, normal saline
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Pennsylvania
Meniscus Tear, Tibial, Pain, Postoperative
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery
The utilization of arthroscopic surgery to treat meniscus injuries has continued to increase in recent years, partly due to a younger, more active population, and improved technology and technique.
- Conditions
- Meniscus Tear, Tibial, Pain, Postoperative, Postoperative Complications, Ketorolac Adverse Reaction
- Trial name
- NCT04246541
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pain, Postoperative, Endodontically Treated Teeth
Postoperative Pain Intensity Associated With the Use of Different Nickel Titanium Instrumentation Systems
In this study the effect of different engine-driven nickel titanium (Ni-Ti) instrumentation systems (OneShape, Revo S and WaveOne) on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root…
- Trial name
- NCT03478241
- Testing
- Group 1: single file rotary motion, Group 2: multiple file rotary motion, Group 3: single file reciprocal motion
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
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