Clinical trials: Pain, Postsurgical, open to volunteers
Pain, Postoperative, Pharmacokinetics
Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy
The purpose of this study is to assess pharmacokinetics of liposomal bupivacaine (Exparel) after multilevel intercostal injections of this local anesthetic for pain control during and after thoracoscopic surgeries.
- Trial name
- NCT03737292
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Pain, Postoperative, Thyroid Diseases
Postoperative Pain of Robotic, Endoscopic and Open Lateral Neck Dissection
Postoperative pain is a good indicator to confirm the advantages of the surgical methods in the era of minimally invasive surgery.
- Conditions
- Pain, Postoperative, Thyroid Diseases, Surgery
- Trial name
- NCT06803732
- Testing
- Observations on postoperative pain intensity
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai 6th People's Hospital
Carpal Tunnel Surgery, Trigger Finger Disorder
NAC-REPAIR for Post-surgical Pain
This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating…
- Conditions
- Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal
- Trial name
- NCT07227649
- Testing
- NAC
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Arizona
Postoperative Pain
Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE）
This national, multi-center, randomized controlled study, through the study of intravenous injection of estaketamine in elderly patients undergoing surgery, is expected to explore whether estaketamine can improve the acute…
- Trial name
- NCT07063108
- Testing
- Esketamine hydrochloride, Saline
- Volunteers
- 276 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Pain, Postoperative Complications
Protocol for Accelerated Recovery in Patients Undergoing Thoracic Surgical Procedures (PROSM). Study Randomized Comparative Between the Adoption of the Proposed Guidelines and the Traditional Method Currently Used in the Institution
Introduction: Aiming at reducing costs and optimizing the use of these financial resources, several postoperative recovery protocols have emerged that aim to reduce the length of hospital stay by accelerating surgical…
- Conditions
- Postoperative Pain, Postoperative Complications, Postoperative Nausea, Lung Cancer
- Trial name
- PROSM (NCT03271749)
- Testing
- PROSM guidelines for preoperative, anesthesia and postoperative care for lung resections
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Igor Renato Louro Bruno de Abreu
Post Operative Pain, Acute
A Study of Combogesic® 325 in Adolescent Patients With Moderate to Severe Postoperative Pain Associated With Orthopedic Surgery
Combogesic® 325 contains a combination of ibuprofen and acetaminophen. The purpose of this study is to compare the pain relief effects of Combogesic® 325mg and acetaminophen and to evaluate the safety of Combogesic® 325mg in…
- Trial name
- NCT07225140
- Testing
- Combogesic® tablets, Acetaminophen 500mg
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- AFT Pharmaceuticals, Ltd.
Opioid Use, Lumbar Spinal Stenosis
Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression
This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy.
- Conditions
- Opioid Use, Lumbar Spinal Stenosis, Pain, Postoperative, Pain, Back
- Trial name
- NCT05058287
- Testing
- Depo-Medrol 40Mg/Ml Suspension for Injection
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Hospital for Special Surgery, New York
Joint (Knee or Hip Replacement)
The Impact of Extending Sleep Before Joint-replacement Surgery on Post-surgical Pain
This study will evaluate the impact of sleep banking on joint replacement surgery recovery.
- Trial name
- NCT07383584
- Testing
- Sleep banking
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Total Ankle Arthroplasty, Postsurgical Analgesia
Efficacy of EXPAREL vs. Bupivacaine
The goal of this clinical study is to learn about pain management strategies in subjects undergoing total ankle replacement. arthroplasty surgery The primary objective is to compare the magnitude of the analgesic effect following…
- Trial name
- NCT07212114
- Testing
- EXPAREL, 0.25% bupivacaine (HCl): 50 ml, 0.25% bupivacaine (HCl): 30 ml
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Emory University
Total Hip Arthroplasty (THA), Postoperative Pain Management
Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthroplasty
Background: In recent years, regional anesthesia has become more popular because it can reduce pain and the need for strong pain medications like morphine. For hip surgery, the PENG block is already known to be effective.
- Conditions
- Total Hip Arthroplasty (THA), Postoperative Pain Management, Peripheral Nerve Blocks, PENG Block
- Trial name
- NCT06964282
- Testing
- PENG Block, Iliopsoas nerve block
- Where
- Belgium
- Volunteers
- 118 people
- Sponsor
- University of Liege
Cesarean Birth, Patient Education
Nursing Education Provided After Cesarean Section Surgery.
The aim of this study is to determine the effect of individual education given after cesarean section on the levels of pain and anxiety in women in the postoperative period.
- Trial name
- NCT07467304
- Testing
- Experimental: Experimental: Intervention group - Training group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Sleep, Pediatrics
Postoperative Pain After Pediatric Adenotonsillectomy With Ketorolac or Ibuprofen
This prospective observational study will evaluate postoperative pain after outpatient pediatric adenotonsillectomy in adolescents prescribed either acetaminophen with ibuprofen or acetaminophen with oral ketorolac after…
- Conditions
- Sleep, Pediatrics, Adenotonsillectomy
- Trial name
- NCT07672418
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baylor College of Medicine
Post Operative Pain, Acute
Effect of Two Different Concentrations of Sodium Hypochlorite on Post-Operative Pain Following Single-Visit Root Canal Treatment
This randomized controlled trial aims to evaluate the effect of two different concentrations of sodium hypochlorite (2.5% and 5.25%) on post-operative pain following single-visit root canal treatment.
- Trial name
- NaOCl-RCT (NCT07618182)
- Testing
- Sodium Hypochlorite Irrigation
- Volunteers
- 116 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Post Operative Analgesia
Erector Spinae Plane Versus Quadratus Lumborum Blocks for Pain Management After Total Abdominal Hysterectomy
TAH, being a large scale gynaecological operation, is a construction bound to cause serious postoperative pain to the patient in that the procedure will inevitably entail massive tissue dissection.
- Trial name
- NCT07480499
- Testing
- Erector Spinae Plane Block, Quadratus Lumborum Block (QLB)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Breast Cancer, Postoperative Pain
Comparison of Postoperative Analgesic Efficacy of Two Different Blocks in Modified Radical Mastectomy Surgery
Postoperative pain following modified radical mastectomy remains a significant clinical challenge and may delay recovery, impair patient comfort, and increase opioid consumption.
- Trial name
- mastectomy (NCT07737132)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Ultrasound-Guided Serratus Anterior Plane Block (SAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Postoperative Pain, Chronic Postsurgical Pain
Perioperative Quantitative Sensory Testing and Incision Pain Mapping in Thoracic Surgery
Postoperative pain remains a common and clinically important burden after thoracic surgery and may progress to chronic postsurgical pain.
- Conditions
- Postoperative Pain, Chronic Postsurgical Pain, Thoracic Surgery, Lung Resection
- Trial name
- NCT07653932
- Testing
- Perioperative QST and incision pain mapping assessment
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Tongji Hospital
Post-operative Pain
Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries
This study aims to evaluate the effect of adding dexmedetomidine to bupivacaine in erector spinae plane (ESP) blocks on the duration of postoperative analgesia in pediatric patients undergoing lower abdominal surgery.
- Trial name
- NCT07023991
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs
Non-steroidal Anti-inflammatory in Cardiac Surgery
Non-steroidal anti-inflammatory drugs (NSAID) are part the multimodal strategy in pain management after surgery. However, major concerns are raised in cardiac surgery given the potential side effects of NSAID with more bleeding…
- Conditions
- Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs, Cardiac Surgery, Pain Intensity
- Trial name
- KETOPAIN (NCT06381063)
- Testing
- pain management, ketoprofen
- Where
- France
- Volunteers
- 238 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Breast Cancer, Postoperative Pain
Ultrasound-Guided SPSIP Versus ESPB for Postoperative Pain After Modified Radical Mastectomy
Breast cancer is the most common cancer affecting women worldwide. Modified radical mastectomy is one of the main surgical treatments for breast cancer.
- Conditions
- Breast Cancer, Postoperative Pain, Acute Post-surgical Pain
- Trial name
- SPSIP-ESPB (NCT07446868)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Osteo Arthritis of the Knee, Total Knee Anthroplasty
Dinalbuphine Sebacate in Postoperative Pain Control After TKA
To evaluate the effectiveness of Dinalbuphine Sebacate for controlling subacute pain after total knee arthroplasty
- Trial name
- Naldebain (NCT07140510)
- Testing
- Dinalbuphine Sebacate, Normal Saline
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Thammasat University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.