Clinical trials: Pain, Somatic
Cancer Survivor, Pain
Somatic Yoga and Meditation for Cancer Survivors With Pain From Neuropathy
Chemotherapy-induced peripheral neuropathy syndrome (CIPN) causes significant pain in hands and feet and is an adverse effect of treatment.
- Conditions
- Cancer Survivor, Pain, Chemotherapy Induced Peripheral Neuropathy, Function
- Trial name
- Y4CIPN (NCT03786055)
- Testing
- Somatic Yoga and Meditation (SYM)
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Stockton University
Sacroiliac Joint Somatic Dysfunction, Pain
Effects of Mulligan's Mobilization With and Without Clamshell Exercises in Sacroiliac Joint Dysfunction
Sacroiliac joint dysfunction is the changing of joint structure (ligaments, muscles and cartilage) that cause impairments and movement restrictions.
- Conditions
- Sacroiliac Joint Somatic Dysfunction, Pain, Disability Physical, Treatment
- Trial name
- NCT05347537
- Testing
- Mulligan mobilization, clamshell exercise
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Quality of Life, Neuropathic Pain
Effects of Occlusal Splint and Therapeutic Home Exercises
In this randomized controlled study, investigators planned to investigate the efficacy of oral occlusive splint and therapeutic home exercises in increasing the quality of life and reducing somatic and neuropathic pain in…
- Conditions
- Quality of Life, Neuropathic Pain, Somatic Pain
- Trial name
- NCT04116255
- Testing
- Mandibular oral occlusal splint, Temporomandibular joint Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ankara Training and Research Hospital
Ulcer
Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450216
- Testing
- Ibuprofen/famotidine, Ibuprofen
- Volunteers
- 906 people
- Sponsor
- Amgen
Placebo, Expectations
Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain
The investigators administer a functional neuroimaging task to investigate the effect of cue expectancy on participants' self-reported ratings across a variety of affective and cognitive domains.
- Trial name
- NCT05425563
- Testing
- Pain Expectancy Cues, Vicarious Pain Expectancy Cues, Cognitive Effort Expectancy Cues
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Somatic Pain, Neuropathic Pain
C2-C4 Compartment Block Versus Block of Costagliola, in TEAC
C2-C4 compartment block compared to the Costaiola block, in the control of persistent postoperative pain (somatic and neuropathic) in patients undergoing carotid thromboendarterectomy
- Trial name
- TEAC (NCT03409068)
- Testing
- C2-C4 compartment anesthetic block, Costagliola block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Joint Pain
Study to Evaluate the Safety and Efficacy of a Proprietary "Joint Health" Dietary Supplement in Subjects With Joint and Connective Tissue Pain
This study is designed to evaluate the effectiveness of a proprietary nutritional supplement that contains Krill Oil (KO), astaxanthin (AX) and hyaluronic acid (HA) to reduce pain and discomfort in participants, compared to an…
- Trial name
- NCT03209895
- Testing
- Joint Health Product, Glucosamine / Chondroitin
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- U.S. Nutraceuticals, LLC
Sacroiliac Joint Somatic Dysfunction
Comparative Effects of Stabilization Exercises and Muscle Energy Techniques in Sacroiliac Joint Pain
Sacroiliac joint is in pelvis. It links the iliac bone (pelvic) bone to the sacrum. This joint pain is due to hyper mobility or instability of the joint, it may also cause by damage to joint between the spine and hip.
- Trial name
- NCT05356390
- Testing
- Stabilization exercises, Muscle energy techniques
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Hypovolemia, Somatic Pain
Influence of Variations of Systemic Venous Return on Analgesia Nociception Index (ANI) During General Anaesthesia
The purpose of this study is to determine whether the value of analgesia nociception index (ANI) is influenced by variations of systemic venous return (cardiac preload) under general anaesthesia.
- Trial name
- NCT02193412
- Testing
- noxious stimulus, change in operating table slope: head-down tilt position, change in operating table slope: head-up tilt position
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
VEXAS Syndrome
A 52-Week Study Evaluating the Efficacy and Safety of Arumakimig (MAS825) in Participants With VEXAS Followed by Open-Label Extension (OLE) Period
The purpose of this study is to evaluate clinical efficacy and safety of arumakimig (MAS825) compared to placebo in patients with Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) syndrome.
- Trial name
- NCT07748624
- Testing
- Arumakimig, Oral glucocorticoids
- Where
- 4 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Novartis Pharmaceuticals
Healthy Volunteer
The Accuracy and Efficacy of AI-driven tVNS Algorithm
Pain, including somatic and visceral pain, is a common symptom. Persistent pain can lead to repetitive visits to hospitals and can limit patients' daily activities, which can result in tremendous medical cost and lower quality of…
- Trial name
- NCT05215756
- Testing
- transcutaneous vagal nerve stimulation
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Osteoarthritis, Rheumatoid Arthritis
Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216)
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- HZ-CA-304 (NCT00613106)
- Testing
- HZT-501, Ibuprofen
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Amgen
Soft Tissue Injuries
Treatment of Posttraumatic Swelling and Pain With Zhi Kang Capsule
Zhi Kang Capsule functions for hemostasis and detumescence and can be used for traumatic bleeding, uterine bleeding, hematemesis and hematochezia.This randomized controlled trial was conducted to confirm the efficacy and safety…
- Trial name
- NCT03363971
- Testing
- Zhi Kang Capsule, Simulant agent for Zhi Kang Capsule
- Where
- China
- Volunteers
- 2,200 people
- Sponsor
- Peking University People's Hospital
Back Pain, Back Pain Lower Back
Use of Ultrasound Imaging in Confirming Osteopathic Spinal Diagnosis
In the field of Osteopathic Medicine, diagnosis of potential areas of dysfunction are diagnosed by the physician using their hands and expertise in noticing subtle differences in symmetry, tone, swelling etc..
- Conditions
- Back Pain, Back Pain Lower Back, Back Pain Lower Back Chronic, Back Pain With Radiation
- Trial name
- NCT07858071
- Testing
- Spinal Ultrasound
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Soft Tissue Injuries
Clinical Efficacy and Safety of Compound Methyl Salicylate Liniment
This clinical trial program was established according to the ethical principles of the Helsinki declaration and the GCP guiding principle, and a randomized grouping method was used to evaluate the efficacy and safety of Compound…
- Trial name
- NCT03362216
- Testing
- Compound Methyl Salicylate Liniment, Diclofenac Sodium Liniment
- Volunteers
- 216 people
- Sponsor
- Peking University People's Hospital
Pain
From ACute To Chronic Postoperative Pain in Patients for Elective Cholecystectomy
Chronic Pain is a wellknown complication after cholecystectomy. Intensity of the pain in the first week after the operation is a predictive factor for the development of chronic pain, but it is unknown whether the risk is more…
- Trial name
- FACTS1 (NCT01553253)
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Pain
ADVANCE: Assessment for Defining Variability in Anesthesia Through Novel Clinical EEG
The present study is designed to compare prospectively whether sBIS, sEMG, or CVI variability (brain monitoring) can be used to predict unwanted intraoperative responses (high blood pressure, fast heart rate, tearing, etc.) to…
- Trial name
- CVI (NCT00689130)
- Where
- 4 sites in United States, Spain
- Volunteers
- 120 people
- Sponsor
- Medtronic - MITG
Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic)
Post Operative Pain and Vagal Stimulation
Anorectal surgery is a type of surgery that can cause anal pain, particularly in the context of hemorrhoid surgery or anal fissure surgery. Generally, the period of discomfort related to the pain lasts about two weeks.
- Conditions
- Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic), Vagal Nerve Stimulation
- Trial name
- VAGANAL (NCT07659314)
- Testing
- Experimental arm, Control arm
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Pain (Visceral, Somatic, or Neuropathic), Hip Arthroplasty Replacement
Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study
Despite high success rates of hip and knee arthroplasty, up to 20% of patients report moderate-to-severe pain (NRS > 3) persisting beyond the expected healing period.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Hip Arthroplasty Replacement, Knee Arthroplasty, Total, Survey and Questionnaire
- Trial name
- PAIN-COMPO (NCT07110324)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Elderly (People Aged 65 or More)
The Effects of Somatic-Based Chair Exercises in the Elderly
The primary aim of this study is to investigate the effects of easily applicable somatic-based chair exercises on balance and pain in the elderly.
- Trial name
- NCT07618143
- Testing
- Somatic-Based Chair Exercises, Conventional Exercise Group
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Gedik University