Clinical trials: Pain, completed
Stroke
The Role of Peripheral Afferents in Modulating Post-stroke Central Pain
Central post-stroke pain (CPP) is extremely difficult to relieve and responds very poorly to analgesics targeting neuropathic pain, probably because the mechanisms underlying this pain remain poorly understood.
- Trial name
- APEDOC (NCT06446960)
- Testing
- Lidocaine 20mg/ml, Levobupivacaine Hydrochloride 1.25 MG/ML, Sodium Chloride 0.9% Inj
- Where
- 2 sites in France
- Volunteers
- 33 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
or Peripheral Nerve Injury (PNI), Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN)
Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch
The Summary of product characteristics (SmPC) for QUTENZA advises that topical anaesthetic is applied prior to the application of QUTENZA.
- Trial name
- LIFT (NCT01416116)
- Testing
- QUTENZA, Lidocaine, Tramadol
- Where
- 20 sites in Belgium, Czechia and 5 more
- Volunteers
- 122 people
- Sponsor
- Astellas Pharma Inc
Pilates Exercise, Mirror Therapy
Pilates Exercises Versus Mirror Therapy on Shoulder Dysfunction Post Neck Dissection Surgeries
The purpose of this study is to compare the therapeutic effects of pilates exercises and mirror therapy on shoulder dysfunction post-neck dissection surgeries.
- Conditions
- Pilates Exercise, Mirror Therapy, Shoulder Pain, Dissection
- Trial name
- NCT07297706
- Testing
- Pilates exercises, Mirror therapy, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Lumbosacral Radiculopathy
Effects of Multimodal Physical Therapy in Patients With Lumbosacral Radiculopathy
Purposes of the study To investigate the effect of Multimodal Physical Therapy on pain, daiablility H-reflex, and Diffusion Tensor Imaging (DTI) Parameters in Patients With Lumbosacral Radiculopathy.
- Trial name
- NCT06058806
- Testing
- Multimodal Physical Therapy
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Cairo University
Knee Osteoarthritis
Comparison of the Efficacy of Duloxetine and Pregabalin in Patients With Knee Osteoarthritis With Mix Type Pain
Osteoarthritis (OA) is a common degenerative joint disorder associated with chronic pain at older age.It is known that patients with osteoarthritis experience nociceptive and neuropathic pain to varying degrees.
- Trial name
- NCT04532684
- Testing
- Duloxetine, Pregabalin
- Volunteers
- 66 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Whiplash Injuries
Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study
The purpose of this pilot project is to determine the feasibility of a study design to investigate how many sessions of manual therapy and exercise produce the best results for people with whiplash injuries.
- Trial name
- NCT01957033
- Testing
- Exercise and education once/week for 6 weeks, Exercise and education twice/week for 6 weeks, Exercise and education 3 times/week for 6 weeks
- Where
- 3 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Jordan Miller, Graduate Student
Chronic Low Back Pain
Robot Coach of Chronic Low Back Pain Patient
The objective of KERAAL technological project is to create a new intelligent robot which allows a humanoid robot to record then to show and to follow the progress of rehabilitation sessions proposed by a physiotherapist to a…
- Trial name
- RCOOL (NCT03260738)
- Testing
- Rehabilitation program with Poppy robot, Usual rehabilitation program
- Where
- 2 sites in France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Brest
Postoperative Pain
Massage After Surgery To Help Treat Post-Operative Pain
Postoperative pain is often undertreated. Although studies have demonstrated that many patients experience a substantial degree of unrelieved pain following operative procedures and that this pain can increase the incidence of…
- Trial name
- NCT00057148
- Testing
- massage treatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- US Department of Veterans Affairs
SPINAL Fracture
Short Segment vs Long Segment Fixation in Traumatic Dorsolumbar Spine Fractures
A prospective study included 91 patients, who had single level thoracolumbar fracture with Cobb's angle ≤ 25⁰, underwent posterior fixation.
- Trial name
- NCT03272243
- Testing
- short segment posterior spine fixation, long segment posterior spine fixation
- Volunteers
- 91 people
- Sponsor
- Ain Shams University
Cervical Radiculopathy
Effects of Thoracic Screw Manipulation in Patients With Cervical Radiculopathy
Cervical radiculopathy is a pain and/or sensorimotor deficit syndrome that is defined as being caused by compression of a cervical nerve root.
- Trial name
- NCT05749835
- Testing
- Thoracic Manipulation and Sustained Natural Apophyseal Glides and conventional therapy, Sustained Natural Apophyseal Glides and conventional therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Pain, Needle Stick
Testing the Effectiveness of a Parent and Child Mindfulness-Based Intervention for Child Venipuncture
This study investigates the impact of mindfulness-based intervention for children undergoing a blood-draw and their accompanying parent on (a) child ratings of pain and fear, (b) parent and child ratings of parent distress, and…
- Trial name
- NCT03941717
- Testing
- Mindfulness-Based Condition, Unfocused attention Condition
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Cancer Pain, Chronic Pain
Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain
This Registry study will prospectively evaluate the differences in treatment outcomes in terms of pain intensity, pain interference, concomitant medication use, health-related quality of life, opioid adverse effects, and…
- Conditions
- Cancer Pain, Chronic Pain, Cancer Associated Pain, Neuropathic Pain
- Trial name
- NCT05674240
- Testing
- Intrathecal Targeted Drug Delivery, Conservative medical management
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Pain, Video-Assisted Thoracoscopic Surgery
SPSIP Block vs SAP Block for Post-VATS Pain
Comparison of Superior Serratus Posterior Intercostal Plane Block and Serratus Anterior Plane Block for Pain Management Following Video-Assisted Thoracoscopic Surgery: A Prospective Observational Cohort Study Introduction…
- Trial name
- NCT07467291
- Testing
- Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Firat University
Rotator Cuff Tear
Clinical Research Study of the Benefits of BREG Polar Care Wave to Reduce Opioid Use by Patients Having Undergone Arthroscopic Rotator Cuff Repair Shoulder Surgery
The goal of this clinical trial is to compare effect of cold compression to standard of care in patients undergoing rotator cuff repair.
- Trial name
- CCROUT (NCT07455474)
- Testing
- Breg Polar Care Wave Cold Compression Device
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Nevada, Reno
Kinesiophobia
Impact of Kinesiophobia on Descending Corticospinal and Bulbospinal Projections
Fear of movement (kinesiophobia) is a phenomenon commonly observed in people suffering from chronic pain. The aims of this project are to better understand the neurophysiological basis of this phenomenon, in particular 1) the…
- Trial name
- EchoKinésio (NCT05161832)
- Testing
- Nocebo
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Cerebral Palsy, Muscle Hypertonia
Evaluation of the Effect of the Presence Of Clowns on Pain and Anxiety Seen During Injections Botulinum Toxin in Child
In children requiring botulinum toxin injections, improving supervisory procedures of injection sessions to reduce pain and improve the experience of this invasive procedure is needed.
- Trial name
- CLOWN-TOX (NCT03149263)
- Testing
- distraction
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Appendicitis
Ultrasound-guided Abdominal Wall Nerve Blockade in Laparoscopic Surgery for Acute Appendicitis.
Acute appendicitis is a common disease and usually occurs within the ages of 10-30 years old." Ten percent of the population will get this disease during a lifetime." At Bispebjerg hospital it is one of the most common acute…
- Trial name
- BD-TAP APP (NCT01825863)
- Testing
- Ropivacaine, Saline 9%
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Bispebjerg Hospital
Postoperative Pain
Protracted Mixture of Local Anesthetics for Major Foot and Ankle Surgery
To extend the duration of peripheral nerve blockade after major foot and ankle surgery the investigators randomize the postoperative treatment with either perineurial sciatic nerve blocks with 0.5% Bupivacaine-Epinephrine with or…
- Trial name
- NCT02526199
- Testing
- Bupivacaine, Epinephrine, Dexamethasone
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Rasmus Wulff Hauritz
Chronic Neck Pain
The Comparison of Pilates with Cognitive Functional Therapy in Adults with Chronic Neck Pain
The aim of this study is to compare the effectiveness of Pilates compared with Cognitive Functional Therapy in adults with chronic neck pain.
- Trial name
- NCT06225063
- Testing
- Pilates, Cognitive Functional Therapy
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- European University Cyprus
Postoperative Pain
Ultrasound Guided Bilateral Erector Spinae Plane Block in Retropubic Radical Prostatectomy
This study will define the postoperative analgesic effect of ESP block via amount of patient-controlled analgesia (PCA) and postoperative analgesic consumption (such as routinely and rescue analgesics) and compare the control…
- Trial name
- NCT03413163
- Testing
- Ultrasound guided erector spinae plane block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maltepe University
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